STRINGSTRING
ABS21754.1 ABS21754.1 ABS21806.1 ABS21806.1 ABS21920.1 ABS21920.1 ABS21922.1 ABS21922.1 argS argS amj amj ABS21950.1 ABS21950.1 ABS21974.1 ABS21974.1 ABS21975.1 ABS21975.1 ABS22005.1 ABS22005.1 ABS22014.1 ABS22014.1 ABS22016.1 ABS22016.1 thrS thrS ABS22109.1 ABS22109.1 ABS22111.1 ABS22111.1 ABS22155.1 ABS22155.1 ABS22156.1 ABS22156.1 ABS22198.1 ABS22198.1 ABS22208.1 ABS22208.1 ABS22285.1 ABS22285.1 ABS22286.1 ABS22286.1 ABS22322.1 ABS22322.1 ABS22340.1 ABS22340.1 ABS22381.1 ABS22381.1 ABS22412.1 ABS22412.1 ABS22433.1 ABS22433.1 ABS22454.1 ABS22454.1 ABS22602.1 ABS22602.1 ABS22613.1 ABS22613.1 rpsO rpsO infB infB nusA nusA polC polC proS-2 proS-2 frr frr tsf tsf rpsB rpsB ABS22726.1 ABS22726.1 rplS rplS ABS22731.1 ABS22731.1 rpsP rpsP rpmB rpmB fmt fmt def def priA priA rpoZ rpoZ ABS22763.1 ABS22763.1 pyrR pyrR ileS ileS ABS22786.1 ABS22786.1 ABS22787.1 ABS22787.1 murB murB murG murG ABS22795.1 ABS22795.1 murD murD mraY mraY rpoA rpoA rplQ rplQ rplM rplM rpsI rpsI ABS20546.1 ABS20546.1 ddl ddl murF murF ABS20613.1 ABS20613.1 gatC gatC gatA gatA gatB gatB proS proS ABS20773.1 ABS20773.1 UGlcNAcDH UGlcNAcDH ugtP ugtP ABS20833.1 ABS20833.1 uppP uppP ABS20980.1 ABS20980.1 ABS21061.1 ABS21061.1 ABS21062.1 ABS21062.1 ABS21063.1 ABS21063.1 rplD rplD rplC rplC rpsJ rpsJ tuf tuf fusA fusA rpsG rpsG rpsL rpsL ABS20472.1 ABS20472.1 rpoC rpoC rplL rplL rplJ rplJ rplA rplA rplK rplK nusG nusG ABS20463.1 ABS20463.1 cysS cysS gltX gltX lysS lysS ABS20431.1 ABS20431.1 pth pth glmU glmU metG metG ABS20401.1 ABS20401.1 dnaX dnaX serS serS ABS20385.1 ABS20385.1 ABS20378.1 ABS20378.1 ABS21072.1 ABS21072.1 rplI rplI ABS24189.1 ABS24189.1 ABS24152.1 ABS24152.1 ABS24135.1 ABS24135.1 ABS24134.1 ABS24134.1 ABS24132.1 ABS24132.1 ABS24131.1 ABS24131.1 ABS24130.1 ABS24130.1 ABS24128.1 ABS24128.1 ABS24126.1 ABS24126.1 ABS24123.1 ABS24123.1 ABS24118.1 ABS24118.1 ABS24094.1 ABS24094.1 argS-2 argS-2 rpoE rpoE murA-2 murA-2 rho rho rpmE2 rpmE2 tdk tdk prfA prfA murA murA ABS23973.1 ABS23973.1 ABS23957.1 ABS23957.1 ABS23938.1 ABS23938.1 ABS23937.1 ABS23937.1 rpsR rpsR rpsF rpsF rpmH rpmH prfB prfB lgt lgt ABS23897.1 ABS23897.1 ABS23882.1 ABS23882.1 smpB smpB murB-2 murB-2 ABS23799.1 ABS23799.1 glyQS glyQS ABS23716.1 ABS23716.1 glgB glgB glgC glgC ABS23707.1 ABS23707.1 glgA glgA ABS23662.1 ABS23662.1 ABS23661.1 ABS23661.1 leuS leuS ABS23592.1 ABS23592.1 ABS23585.1 ABS23585.1 ABS23568.1 ABS23568.1 murC murC tyrS tyrS rpsD rpsD ABS23507.1 ABS23507.1 polA polA ABS23484.1 ABS23484.1 ABS23483.1 ABS23483.1 thrS-2 thrS-2 infC infC rpmI rpmI rplT rplT pheS pheS pheT pheT asnS asnS ABS23460.1 ABS23460.1 murI murI ABS23418.1 ABS23418.1 valS valS ABS23392.1 ABS23392.1 rplU rplU rpmA rpmA hisS hisS aspS aspS alaS alaS mltG mltG ABS23314.1 ABS23314.1 rpmG2 rpmG2 ABS23291.1 ABS23291.1 ABS23276.1 ABS23276.1 rpsK rpsK rpsT rpsT lepA lepA rpsU rpsU dnaG dnaG sigA sigA ABS23228.1 ABS23228.1 rpmG1 rpmG1 efp efp nusB nusB ABS23086.1 ABS23086.1 ABS23078.1 ABS23078.1 dinB dinB ABS23007.1 ABS23007.1 ABS23004.1 ABS23004.1 ABS22912.1 ABS22912.1 def-2 def-2 ABS22884.1 ABS22884.1 ABS22841.1 ABS22841.1 rpmF rpmF ABS22799.1 ABS22799.1 murE murE trpS trpS ABS21253.1 ABS21253.1 ABS21262.1 ABS21262.1 ABS21267.1 ABS21267.1 ABS21268.1 ABS21268.1 ABS21269.1 ABS21269.1 ABS21270.1 ABS21270.1 ABS21324.1 ABS21324.1 ABS21357.1 ABS21357.1 ABS21415.1 ABS21415.1 dltC dltC ABS21417.1 ABS21417.1 dltA dltA ABS21426.1 ABS21426.1 uppP-2 uppP-2 ABS21464.1 ABS21464.1 ABS21515.1 ABS21515.1 ABS21543.1 ABS21543.1 dinG dinG ABS21591.1 ABS21591.1 ABS21693.1 ABS21693.1 rplW rplW rplB rplB rpsS rpsS rplV rplV rpsC rpsC rplP rplP rpmC rpmC rpsQ rpsQ rplN rplN rplX rplX rplE rplE rpsZ rpsZ rpsH rpsH rplF rplF rplR rplR rpsE rpsE rpmD rpmD rplO rplO infA infA rpmJ rpmJ rpsM rpsM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ABS21754.1ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: oih:OB0449 ABC transporter ATP-binding protein. (522 aa)
ABS21806.1Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: btl:BALH_1727 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (339 aa)
ABS21920.1KEGG: btl:BALH_1925 hypothetical protein. (217 aa)
ABS21922.1ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: btk:BT9727_1982 ABC transporter, ATP-binding protein. (630 aa)
argSTIGRFAM: arginyl-tRNA synthetase; KEGG: bat:BAS2021 arginyl-tRNA synthetase. (562 aa)
amjConserved hypothetical protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (265 aa)
ABS21950.1Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; NTF2 domain protein transpeptidase; KEGG: bat:BAS2084 penicillin-binding protein 3. (661 aa)
ABS21974.1PFAM: glycosyl transferase family 2; KEGG: btl:BALH_2035 glycosyltransferase. (404 aa)
ABS21975.1KEGG: bce:BC2228 hypothetical protein. (373 aa)
ABS22005.1PFAM: phosphoesterase PA-phosphatase related; KEGG: btk:BT9727_2092 phosphatidylglycerophosphatase B. (211 aa)
ABS22014.1PFAM: Monogalactosyldiacylglycerol synthase; KEGG: bcz:pE33L466_0393 possible UDP-glucuronosyltransferase. (382 aa)
ABS22016.1PFAM: phosphoesterase PA-phosphatase related; KEGG: bcz:pE33L466_0399 phosphatase. (176 aa)
thrSthreonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (640 aa)
ABS22109.1PFAM: glycosyl transferase family 2; KEGG: bcz:pE33L466_0435 glycosyltransferase. (513 aa)
ABS22111.1Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: bar:GBAA2559 D-alanyl-D-alanine carboxypeptidase family protein; Belongs to the peptidase S11 family. (337 aa)
ABS22155.1PFAM: glycosyl transferase family 2; KEGG: bce:BC3001 glycosyltransferase involved in cell wall biogenesis. (507 aa)
ABS22156.1PFAM: glycosyl transferase family 2; KEGG: bcz:BCZK2744 glycosyl transferase, group 2 family protein. (503 aa)
ABS22198.1RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: bcz:BCZK2519 RNA polymerase sigma-70 factor; Belongs to the sigma-70 factor family. ECF subfamily. (227 aa)
ABS22208.1KEGG: btk:BT9727_2581 hypothetical protein. (150 aa)
ABS22285.1PFAM: sulfatase; KEGG: bca:BCE_2987 sulfatase; Belongs to the LTA synthase family. (657 aa)
ABS22286.1ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: btl:BALH_2636 ABC transporter, ATP-binding protein. (541 aa)
ABS22322.1PFAM: phosphoesterase PA-phosphatase related; KEGG: btk:BT9727_2497 bacitracin transport permease. (199 aa)
ABS22340.1PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: gka:GK0840 NDP-sugar dehydrogenase. (428 aa)
ABS22381.1TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: sth:STH1634 transcriptional regulator. (157 aa)
ABS22412.1PFAM: UDP-glucose/GDP-mannose dehydrogenase; KEGG: cpe:CPE0494 UDPglucose 6-dehydrogenase. (300 aa)
ABS22433.1KEGG: gka:GK1455 recombinase of Bh.Int-like element. (93 aa)
ABS22454.1PFAM: acyltransferase 3; KEGG: cpe:CPE0208 hypothetical protein. (352 aa)
ABS22602.1PFAM: beta-lactamase; KEGG: bsu:BG10390 penicillin-binding protein 4*. (381 aa)
ABS22613.1TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib; KEGG: bcz:BCZK3053 tryptophanyl-tRNA synthetase. (331 aa)
rpsORibosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. (89 aa)
infBTranslation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (689 aa)
nusANusA antitermination factor; Participates in both transcription termination and antitermination. (366 aa)
polCDNA polymerase III, alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1433 aa)
proS-2prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (566 aa)
frrRibosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (185 aa)
tsfTranslation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (295 aa)
rpsBPFAM: ribosomal protein S2; KEGG: bat:BAS3678 ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (233 aa)
ABS22726.1GTP-binding protein HSR1-related; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (287 aa)
rplSRibosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (114 aa)
ABS22731.1KEGG: btl:BALH_3474 KH domain family; Belongs to the UPF0109 family. (75 aa)
rpsPPFAM: ribosomal protein S16; KEGG: bat:BAS3695 ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. (90 aa)
rpmBPFAM: ribosomal protein L28; KEGG: btl:BALH_3489 ribosomal protein L28 (50S ribosomal protein L28); Belongs to the bacterial ribosomal protein bL28 family. (62 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (314 aa)
defPeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (158 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (801 aa)
rpoZDNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (70 aa)
ABS22763.1PFAM: protein of unknown function DUF814; Fibronectin-binding A domain protein; KEGG: bce:BC3873 fibronectin-binding protein / fibrinogen-binding protein. (569 aa)
pyrRUracil phosphoribosyltransferase; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. (180 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (921 aa)
ABS22786.1RNA polymerase, sigma 28 subunit, FliA/WhiG family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (259 aa)
ABS22787.1RNA polymerase, sigma 28 subunit, FliA/WhiG family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (239 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (306 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (364 aa)
ABS22795.1TIGRFAM: cell division protein FtsW; stage V sporulation protein E; PFAM: cell cycle protein; KEGG: bat:BAS3762 stage V sporulation protein E; Belongs to the SEDS family. (363 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (451 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (324 aa)
rpoADNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (314 aa)
rplQPFAM: ribosomal protein L17; KEGG: btl:BALH_0135 50S ribosomal protein L17. (120 aa)
rplMRibosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (145 aa)
rpsIPFAM: ribosomal protein S9; KEGG: btl:BALH_0142 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (130 aa)
ABS20546.1PFAM: tRNA synthetase class II (G H P and S); KEGG: ret:RHE_CH04045 putative serine--tRNA ligase protein. (352 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation. (362 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (458 aa)
ABS20613.1ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: btk:BT9727_0234 ABC transporter, ATP-binding protein. (659 aa)
gatCglutamyl-tRNA(Gln) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (96 aa)
gatAglutamyl-tRNA(Gln) amidotransferase, A subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (485 aa)
gatBglutamyl-tRNA(Gln) amidotransferase, B subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (476 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (476 aa)
ABS20773.1RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: Sigma-70 region 4 type 2; KEGG: lmo:lmo1099 hypothetical protein. (143 aa)
UGlcNAcDHPFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: bcz:BCZK0417 UDP-N-acetyl-D-mannosamine 6-dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (423 aa)
ugtPMonogalactosyldiacylglycerol synthase; Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta- monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl-sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D- glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta-triglucosyl-DAG (3-O- (beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl-beta-(1->6)-D- glucopyranosyl)-1,2-diac [...] (388 aa)
ABS20833.1PFAM: Threonyl/alanyl tRNA synthetase SAD; KEGG: bha:BH2934 hypothetical protein. (238 aa)
uppPUndecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (270 aa)
ABS20980.1PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: btk:BT9727_0664 conserved hypothetical protein, ErfK/YbiS/YcfS/YnhG family protein. (253 aa)
ABS21061.1KEGG: bat:BAS0843 hypothetical protein. (396 aa)
ABS21062.1PFAM: membrane bound O-acyl transferase MBOAT family protein; KEGG: btl:BALH_0803 alginate O-acetyltransferase; Belongs to the membrane-bound acyltransferase family. (470 aa)
ABS21063.1PFAM: membrane bound O-acyl transferase MBOAT family protein; KEGG: bca:BCE_0976 alginate O-acetyltransferase, putative; Belongs to the membrane-bound acyltransferase family. (485 aa)
rplDRibosomal protein L4/L1e; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (207 aa)
rplCRibosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (210 aa)
rpsJRibosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
tufTranslation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (395 aa)
fusATranslation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] (692 aa)
rpsGRibosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
rpsLRibosomal protein S12; With S4 and S5 plays an important role in translational accuracy. (140 aa)
ABS20472.1PFAM: ribosomal protein L7Ae/L30e/S12e/Gadd45; KEGG: btl:BALH_0102 LSU ribosomal protein L7AE. (82 aa)
rpoCDNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1204 aa)
rplLRibosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (119 aa)
rplJRibosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (166 aa)
rplARibosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (230 aa)
rplKRibosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (141 aa)
nusGNusG antitermination factor; Participates in transcription elongation, termination and antitermination. (177 aa)
ABS20463.1RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-H type; RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: bca:BCE_0093 RNA polymerase sigma-30 factor. (220 aa)
cysSTIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; KEGG: bce:BC0110 cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (465 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (485 aa)
lysSTIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; KEGG: bca:BCE_0075 lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (499 aa)
ABS20431.1PFAM: RNA binding S1 domain protein; KEGG: btl:BALH_0058 S1-type RNA-binding domain protein. (152 aa)
pthAminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. (186 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (459 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. (659 aa)
ABS20401.1TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: bce:BC0037 DNA polymerase III, delta' subunit. (327 aa)
dnaXDNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (562 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (424 aa)
ABS20385.1Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: beta-lactamase; peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: bat:BAS0012 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (439 aa)
ABS20378.1DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (381 aa)
ABS21072.1PFAM: cell cycle protein; KEGG: bce:BC3948 cell division protein ftsW; Belongs to the SEDS family. (381 aa)
rplIRibosomal protein L9; Binds to the 23S rRNA. (148 aa)
ABS24189.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (453 aa)
ABS24152.1RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: bca:BCE_5322 RNA polymerase sigma-70 factor; Belongs to the sigma-70 factor family. ECF subfamily. (183 aa)
ABS24135.1ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bca:BCE_5564 ABC transporter, ATP-binding protein. (517 aa)
ABS24134.1PFAM: glycosyl transferase family 2; KEGG: bce:BC5432 bactoprenol glucosyl transferase. (312 aa)
ABS24132.1PFAM: polysaccharide biosynthesis protein; KEGG: bce:BC5430 oligosaccharide translocase (flippase). (473 aa)
ABS24131.1PFAM: glycosyl transferase family 2; KEGG: bce:BC5429 beta-1,3-N-acetylglucosaminyltransferase. (326 aa)
ABS24130.1KEGG: bce:BC5428 hypothetical protein. (430 aa)
ABS24128.1PFAM: glycosyl transferase family 2; KEGG: bce:BC5427 glycosyltransferase involved in cell wall biogenesis. (242 aa)
ABS24126.1KEGG: btk:BT9727_5104 conserved hypothetical protein, possible permease. (437 aa)
ABS24123.1RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: btl:BALH_2454 RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (176 aa)
ABS24118.1Glycosyl transferase, WecB/TagA/CpsF family; Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid. (246 aa)
ABS24094.1Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: bca:BCE_5518 D-alanyl-D-alanine carboxypeptidase, putative; Belongs to the peptidase S11 family. (425 aa)
argS-2TIGRFAM: arginyl-tRNA synthetase; KEGG: bcz:BCZK5061 arginyl-tRNA synthetase. (556 aa)
rpoEDNA-directed RNA polymerase delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. (169 aa)
murA-2UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (429 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (423 aa)
rpmE2PFAM: ribosomal protein L31; KEGG: bce:BC5331 LSU ribosomal protein L31P. (84 aa)
tdkPFAM: thymidine kinase; KEGG: bat:BAS5179 thymidine kinase. (194 aa)
prfAPeptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (355 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (434 aa)
ABS23973.1RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: bcz:BCZK4947 RNA polymerase sigma-70 factor. (156 aa)
ABS23957.1PFAM: sulfatase; KEGG: bca:BCE_5348 sulfatase; Belongs to the LTA synthase family. (642 aa)
ABS23938.1PFAM: glycosyl transferase family 4; KEGG: bce:BC5203 undecaprenyl-phosphate alpha-N-acetylglucosaminephosphotransferase. (357 aa)
ABS23937.1PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: btl:BALH_4693 UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (371 aa)
rpsRRibosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (77 aa)
rpsFRibosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (95 aa)
rpmHPFAM: ribosomal protein L34; KEGG: bcz:BCZK5185 ribosomal protein L34 (50S ribosomal protein L34); Belongs to the bacterial ribosomal protein bL34 family. (44 aa)
prfBPeptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (327 aa)
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (270 aa)
ABS23897.1PFAM: protein of unknown function DUF368; KEGG: btl:BALH_4649 hypothetical protein. (268 aa)
ABS23882.1TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: sigma-54 factor; sigma-54 factor core-binding region; sigma-54 DNA-binding domain protein; KEGG: btl:BALH_4634 RNA polymerase sigma-54 factor. (435 aa)
smpBSsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] (155 aa)
murB-2UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (304 aa)
ABS23799.1Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: penicillin-binding protein transpeptidase; peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: bca:BCE_5147 D-alanyl-D-alanine carboxypeptidase family protein; Belongs to the peptidase S11 family. (279 aa)
glyQSglycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (458 aa)
ABS23716.1PFAM: RNA binding S1 domain protein; KEGG: btl:BALH_4441 general stress protein 13. (133 aa)
glgB1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (645 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (376 aa)
ABS23707.1TIGRFAM: glucose-1-phosphate adenylyltransferase, GlgD subunit; PFAM: Nucleotidyl transferase; KEGG: btl:BALH_4430 glucose-1-phosphate adenylyltransferase. (340 aa)
glgAGlycogen/starch synthase, ADP-glucose type; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (478 aa)
ABS23662.1KEGG: bca:BCE_4932 hypothetical protein. (417 aa)
ABS23661.1PFAM: sulfatase; KEGG: bce:BC4775 phosphoglycerol transferase. (689 aa)
leuSTIGRFAM: leucyl-tRNA synthetase; KEGG: bca:BCE_4882 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (802 aa)
ABS23592.1Hypothetical protein; KEGG: bsu:BG13586 similar to glycosyltransferase. (327 aa)
ABS23585.1PFAM: polysaccharide biosynthesis protein; virulence factor MVIN family protein; KEGG: bat:BAS4603 polysaccharide biosynthesis family protein. (550 aa)
ABS23568.1PFAM: t-RNA-binding domain protein; KEGG: btk:BT9727_4424 tRNA binding-domain protein; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (201 aa)
murCUDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (436 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (418 aa)
rpsDRibosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (200 aa)
ABS23507.1KEGG: bcz:BCZK4345 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein. (1109 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. (877 aa)
ABS23484.1PFAM: replication initiation and membrane attachment family protein; KEGG: bcz:BCZK4321 DNA replication protein. (466 aa)
ABS23483.1PFAM: Primosomal DnaI domain protein; KEGG: bat:BAS4474 primosomal protein DnaI; Belongs to the DnaA family. (311 aa)
thrS-2threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (643 aa)
infCTranslation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (195 aa)
rpmIPFAM: ribosomal protein L35; KEGG: btl:BALH_4158 50S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family. (66 aa)
rplTRibosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (118 aa)
pheSTIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; KEGG: bat:BAS4456 phenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (344 aa)
pheTTIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: bat:BAS4455 phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (806 aa)
asnSTIGRFAM: asparaginyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; KEGG: bat:BAS4454 asparaginyl-tRNA synthetase. (463 aa)
ABS23460.1PFAM: PHP domain protein; SMART: DNA polymerase X; phosphoesterase PHP domain protein; Helix-hairpin-helix DNA-binding class 1; KEGG: btk:BT9727_4286 DNA polymerase X family. (572 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (267 aa)
ABS23418.1TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ava:Ava_3984 amino acid adenylation; Belongs to the ATP-dependent AMP-binding enzyme family. (2031 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (881 aa)
ABS23392.1PFAM: intron maturase type II; RNA-directed DNA polymerase (Reverse transcriptase); KEGG: dsy:DSY4652 hypothetical protein. (543 aa)
rplURibosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (102 aa)
rpmAPFAM: ribosomal protein L27; KEGG: bca:BCE_4534 ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. (96 aa)
hisSTIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; KEGG: bca:BCE_4486 histidyl-tRNA synthetase. (423 aa)
aspSaspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (589 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (880 aa)
mltGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (355 aa)
ABS23314.1PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: btl:BALH_3963 penicillin-binding protein. (584 aa)
rpmG2PFAM: ribosomal protein L33; KEGG: bat:BAS4240 ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (49 aa)
ABS23291.1RNA polymerase, sigma 28 subunit, FliA/WhiG family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (237 aa)
ABS23276.1TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; KEGG: bca:BCE_4404 DNA polymerase III delta subunit. (336 aa)
rpsKRibosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (129 aa)
rpsTRibosomal protein S20; Binds directly to 16S ribosomal RNA. (85 aa)
lepAGTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (608 aa)
rpsUPFAM: ribosomal protein S21; KEGG: btl:BALH_3899 30S ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family. (57 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (598 aa)
sigARNA polymerase, sigma 70 subunit, RpoD family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (373 aa)
ABS23228.1PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: bce:BC4270 penicillin-binding protein. (705 aa)
rpmG1PFAM: ribosomal protein L33; KEGG: bca:BCE_4346 ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (49 aa)
efpTranslation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (185 aa)
nusBNusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (130 aa)
ABS23086.1PFAM: cell cycle protein; KEGG: bcz:BCZK3911 cell division protein, FtsW/RodA/SpoVE family; Belongs to the SEDS family. (392 aa)
ABS23078.1PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: btk:BT9727_3894 conserved hypothetical protein, possible ErfK/SrfK protein. (169 aa)
dinBDNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (412 aa)
ABS23007.1Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: btl:BALH_3693 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (392 aa)
ABS23004.1RNA polymerase, sigma 28 subunit, FliA/WhiG family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (252 aa)
ABS22912.1PFAM: protein of unknown function DUF1447; KEGG: bce:BC3976 putative transcriptional regulator; Belongs to the UPF0356 family. (70 aa)
def-2Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (208 aa)
ABS22884.1PFAM: cell cycle protein; KEGG: bce:BC3948 cell division protein ftsW; Belongs to the SEDS family. (391 aa)
ABS22841.1RNA polymerase, sigma 28 subunit, FliA/WhiG family; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; KEGG: bat:BAS3823 prophage LambdaBa02, RNA polymerase sigma-F factor, putative. (242 aa)
rpmFTIGRFAM: ribosomal protein L32; PFAM: ribosomal L32p protein; KEGG: bat:BAS3774 ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. (57 aa)
ABS22799.1TIGRFAM: stage V sporulation protein D; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: bce:BC3915 stage V sporulation protein D / sporulation specific D,D-transpeptidase. (638 aa)
murEUDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (491 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (329 aa)
ABS21253.1PFAM: cell cycle protein; KEGG: bce:BC1203 cell division protein FtsW; Belongs to the SEDS family. (386 aa)
ABS21262.1PFAM: glycosyl transferase family 2; KEGG: bce:BC1204 glycosyltransferase. (311 aa)
ABS21267.1KEGG: bce:BC1210 hypothetical protein. (225 aa)
ABS21268.1KEGG: btk:BT9727_1114 possible streptomycin biosynthesis StrF domain protein. (226 aa)
ABS21269.1PFAM: Nucleotidyl transferase; KEGG: btl:BALH_1075 glucose-1-phosphate thymidylyltransferase. (257 aa)
ABS21270.1dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (182 aa)
ABS21324.1Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: bcz:BCZK1171 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (423 aa)
ABS21357.1PFAM: beta-lactamase; KEGG: bld:BLi01294 PbpE; Belongs to the class-A beta-lactamase family. (358 aa)
ABS21415.1PFAM: DltD domain protein; DltD central domain protein; KEGG: bce:BC1369 protein dltD precursor. (391 aa)
dltCD-alanyl carrier protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. (79 aa)
ABS21417.1Membrane bound O-acyl transferase MBOAT family protein; Could be involved in the transport of activated D-alanine through the membrane. (388 aa)
dltAD-alanine-activating enzyme; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-dependent AMP [...] (504 aa)
ABS21426.1PFAM: sulfatase; KEGG: lin:lin0647 hypothetical protein; Belongs to the LTA synthase family. (609 aa)
uppP-2Putative undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (263 aa)
ABS21464.1PFAM: sulfatase; KEGG: bca:BCE_1538 sulfatase; Belongs to the LTA synthase family. (628 aa)
ABS21515.1Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: bca:BCE_1594 D-alanyl-D-alanine carboxypeptidase family protein; Belongs to the peptidase S11 family. (373 aa)
ABS21543.1PFAM: RNA binding S1 domain protein; KEGG: bce:BC1498 30S ribosomal protein S1. (382 aa)
dinGDnaQ family exonuclease/DinG family helicase, putative; 3'-5' exonuclease. (929 aa)
ABS21591.1TIGRFAM: primosome, DnaD subunit; PFAM: DnaD and phage-associated region; KEGG: btl:BALH_1398 DNA replication protein. (235 aa)
ABS21693.1PFAM: glycosyl transferase family 2; TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: lwe:lwe0657 glycosyl transferase, group 2 family protein. (633 aa)
rplWRibosomal protein L25/L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (96 aa)
rplBRibosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (276 aa)
rpsSRibosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa)
rplVRibosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). (113 aa)
rpsCRibosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (219 aa)
rplPRibosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (144 aa)
rpmCPFAM: ribosomal protein L29; KEGG: btl:BALH_0116 50S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (66 aa)
rpsQRibosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (87 aa)
rplNRibosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa)
rplXRibosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (103 aa)
rplERibosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (179 aa)
rpsZRibosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. (61 aa)
rpsHRibosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa)
rplFRibosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (179 aa)
rplRRibosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (120 aa)
rpsERibosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. (166 aa)
rpmDPFAM: ribosomal protein L30; KEGG: btl:BALH_0126 50S ribosomal protein L30. (60 aa)
rplORibosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (146 aa)
infATranslation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (72 aa)
rpmJPFAM: ribosomal protein L36; KEGG: bca:BCE_0134 ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. (37 aa)
rpsMRibosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (121 aa)
Your Current Organism:
Bacillus cytotoxicus
NCBI taxonomy Id: 315749
Other names: B. cytotoxicus NVH 391-98, Bacillus cereus NVH 391-98, Bacillus cereus subsp. cytotoxicus NVH 391-98, Bacillus cereus subsp. cytotoxis NVH 391-98, Bacillus cytotoxicus NVH 391-98, Bacillus cytotoxicus str. NVH 391-98, Bacillus cytotoxicus strain NVH 391-98, Bacillus cytotoxis NVH 391-98
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