STRINGSTRING
BPUM_1212 BPUM_1212 BPUM_1227 BPUM_1227 BPUM_1233 BPUM_1233 BPUM_1248 BPUM_1248 BPUM_1258 BPUM_1258 BPUM_1310 BPUM_1310 BPUM_1334 BPUM_1334 BPUM_1426 BPUM_1426 fapR fapR BPUM_1495 BPUM_1495 codY codY BPUM_1585 BPUM_1585 BPUM_1586 BPUM_1586 BPUM_1590 BPUM_1590 BPUM_1643 BPUM_1643 BPUM_1670 BPUM_1670 lexA lexA BPUM_1717 BPUM_1717 BPUM_1722 BPUM_1722 BPUM_1729 BPUM_1729 BPUM_1746 BPUM_1746 BPUM_1758 BPUM_1758 BPUM_0031 BPUM_0031 BPUM_0083 BPUM_0083 BPUM_0157 BPUM_0157 BPUM_0160 BPUM_0160 BPUM_0174 BPUM_0174 BPUM_0200 BPUM_0200 BPUM_0214 BPUM_0214 BPUM_0226 BPUM_0226 BPUM_0238 BPUM_0238 BPUM_0295 BPUM_0295 BPUM_0308 BPUM_0308 BPUM_0326 BPUM_0326 BPUM_0353 BPUM_0353 BPUM_0360 BPUM_0360 BPUM_0361 BPUM_0361 BPUM_0384 BPUM_0384 BPUM_0388 BPUM_0388 BPUM_0397 BPUM_0397 ALS35544.1 ALS35544.1 BPUM_0418 BPUM_0418 BPUM_0446 BPUM_0446 BPUM_0472 BPUM_0472 BPUM_0486 BPUM_0486 BPUM_0494 BPUM_0494 BPUM_0506 BPUM_0506 rex rex BPUM_0588 BPUM_0588 BPUM_0591 BPUM_0591 BPUM_0659 BPUM_0659 BPUM_0663 BPUM_0663 BPUM_0668 BPUM_0668 BPUM_0672 BPUM_0672 BPUM_0713 BPUM_0713 BPUM_0730 BPUM_0730 BPUM_0766 BPUM_0766 BPUM_0780 BPUM_0780 BPUM_0786 BPUM_0786 recX recX BPUM_0827 BPUM_0827 BPUM_0829 BPUM_0829 BPUM_0893 BPUM_0893 BPUM_0902 BPUM_0902 hpr hpr BPUM_0981 BPUM_0981 BPUM_1029 BPUM_1029 BPUM_1122 BPUM_1122 BPUM_1126 BPUM_1126 BPUM_1135 BPUM_1135 BPUM_1138 BPUM_1138 BPUM_1195 BPUM_1195 hrcA hrcA BPUM_2309 BPUM_2309 BPUM_2330 BPUM_2330 BPUM_2334 BPUM_2334 BPUM_2352 BPUM_2352 BPUM_2393 BPUM_2393 ruvB ruvB BPUM_2429 BPUM_2429 BPUM_2494 BPUM_2494 BPUM_2495 BPUM_2495 BPUM_2497 BPUM_2497 BPUM_2553 BPUM_2553 BPUM_2572 BPUM_2572 BPUM_2592 BPUM_2592 BPUM_2598 BPUM_2598 BPUM_2647 BPUM_2647 BPUM_2662 BPUM_2662 BPUM_2677 BPUM_2677 BPUM_2736 BPUM_2736 BPUM_2772 BPUM_2772 BPUM_2808 BPUM_2808 BPUM_2916 BPUM_2916 BPUM_2921 BPUM_2921 BPUM_2953 BPUM_2953 BPUM_2989 BPUM_2989 BPUM_2998 BPUM_2998 BPUM_3039 BPUM_3039 BPUM_3044 BPUM_3044 BPUM_3058 BPUM_3058 BPUM_3062 BPUM_3062 BPUM_3132 BPUM_3132 BPUM_3140 BPUM_3140 BPUM_3155 BPUM_3155 BPUM_3162 BPUM_3162 BPUM_3270 BPUM_3270 BPUM_3273 BPUM_3273 BPUM_3292 BPUM_3292 BPUM_3414 BPUM_3414 BPUM_3418 BPUM_3418 BPUM_3485 BPUM_3485 BPUM_3507 BPUM_3507 BPUM_3514 BPUM_3514 BPUM_3529 BPUM_3529 BPUM_3541 BPUM_3541 BPUM_3558 BPUM_3558 BPUM_3583 BPUM_3583 BPUM_3594 BPUM_3594 BPUM_3603 BPUM_3603 BPUM_3611 BPUM_3611 BPUM_3647 BPUM_3647 BPUM_3663 BPUM_3663 BPUM_3667 BPUM_3667 BPUM_3689 BPUM_3689 BPUM_3710 BPUM_3710 BPUM_2257 BPUM_2257 argR argR BPUM_2154 BPUM_2154 BPUM_2117 BPUM_2117 BPUM_2084 BPUM_2084 BPUM_2076 BPUM_2076 scpB scpB BPUM_2045 BPUM_2045 BPUM_2042 BPUM_2042 birA birA BPUM_1967 BPUM_1967 BPUM_1902 BPUM_1902 BPUM_1875 BPUM_1875 BPUM_1852 BPUM_1852 BPUM_1843 BPUM_1843 BPUM_1841 BPUM_1841 BPUM_1830 BPUM_1830 BPUM_1815 BPUM_1815 BPUM_1789 BPUM_1789 BPUM_1771 BPUM_1771 BPUM_1765 BPUM_1765 sigA sigA BPUM_2241 BPUM_2241 mntR mntR BPUM_1200 BPUM_1200 BPUM_1219 BPUM_1219
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BPUM_1212MarR family transcriptional regulator. (148 aa)
BPUM_1227Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (287 aa)
BPUM_1233MarR family transcriptional regulator. (153 aa)
BPUM_1248Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (163 aa)
BPUM_1258Transcriptional regulator. (151 aa)
BPUM_1310LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (293 aa)
BPUM_1334DeoR family transcriptional regulator. (251 aa)
BPUM_1426Sporulation sigma factor SigE; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (239 aa)
fapRFatty acid biosynthesis transcriptional regulator; Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism. (188 aa)
BPUM_1495Hypothetical protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. (110 aa)
codYTranscriptional repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. (259 aa)
BPUM_1585Cell division protein FtsK; Belongs to the FtsK/SpoIIIE/SftA family. (790 aa)
BPUM_1586GntR family transcriptional regulator. (241 aa)
BPUM_1590MarR family transcriptional regulator. (158 aa)
BPUM_1643Hypothetical protein. (49 aa)
BPUM_1670Rrf2 family transcriptional regulator. (137 aa)
lexAXRE family transcriptional regulator; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (206 aa)
BPUM_1717MarR family transcriptional regulator. (143 aa)
BPUM_1722HxlR family transcriptional regulator. (114 aa)
BPUM_1729MarR family transcriptional regulator. (141 aa)
BPUM_1746Transcriptional regulator. (235 aa)
BPUM_1758PTS N-acetylgalactosamine transporter subunit IID. (678 aa)
BPUM_0031Transcriptional regulator. (277 aa)
BPUM_0083DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; Belongs to the sigma-70 factor family. (218 aa)
BPUM_0157RpiR family transcriptional regulator. (289 aa)
BPUM_0160RNA polymerase subunit sigma; Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription: this protein is involved in detoxification and protection against antimicrobial; Belongs to the sigma-70 factor family. ECF subfamily. (187 aa)
BPUM_0174GntR family transcriptional regulator. (123 aa)
BPUM_0200MarR family transcriptional regulator. (152 aa)
BPUM_0214Transcription antiterminator. (639 aa)
BPUM_0226PadR family transcriptional regulator. (105 aa)
BPUM_0238MarR family transcriptional regulator. (145 aa)
BPUM_0295LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (301 aa)
BPUM_0308Transcriptional regulator. (138 aa)
BPUM_0326GntR family transcriptional regulator. (445 aa)
BPUM_0353LuxR family transcriptional regulator. (227 aa)
BPUM_0360ArsR family transcriptional regulator. (103 aa)
BPUM_0361GntR family transcriptional regulator. (474 aa)
BPUM_0384IclR family transcriptional regulator. (253 aa)
BPUM_0388PTS sugar transporter subunit IIA. (695 aa)
BPUM_0397GntR family transcriptional regulator. (224 aa)
ALS35544.1Transcriptional regulator. (140 aa)
BPUM_0418Chemotaxis protein CheY. (227 aa)
BPUM_0446RNA polymerase sigma-B factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma B is not essential for sporulation; rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation; induced by heat shock, salt stress, oxidative stress, glucose limitation, oxygen limitation and entry into stationary phase. (262 aa)
BPUM_0472MarR family transcriptional regulator. (150 aa)
BPUM_0486Transcriptional regulator. (157 aa)
BPUM_0494LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (297 aa)
BPUM_0506GntR family transcriptional regulator. (492 aa)
rexRedox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. (217 aa)
BPUM_0588RNA polymerase; Belongs to the sigma-70 factor family. ECF subfamily. (181 aa)
BPUM_0591LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (298 aa)
BPUM_0659RpiR family transcriptional regulator. (254 aa)
BPUM_0663Rrf2 family transcriptional regulator. (145 aa)
BPUM_0668RpiR family transcriptional regulator. (243 aa)
BPUM_0672LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (302 aa)
BPUM_0713PadR family transcriptional regulator. (185 aa)
BPUM_0730Transcriptional regulator. (242 aa)
BPUM_0766Transcriptional regulator. (502 aa)
BPUM_0780RNA polymerase subunit sigma-70; Belongs to the sigma-70 factor family. ECF subfamily. (188 aa)
BPUM_0786MarR family transcriptional regulator. (159 aa)
recXRecombinase RecX; Modulates RecA activity; Belongs to the RecX family. (263 aa)
BPUM_0827Fur family transcriptional regulator; Belongs to the Fur family. (145 aa)
BPUM_0829Hypothetical protein. (292 aa)
BPUM_0893Rrf2 family transcriptional regulator. (143 aa)
BPUM_0902RNA polymerase subunit sigma; Belongs to the sigma-70 factor family. ECF subfamily. (163 aa)
hprTranscriptional regulator Hpr; Negative regulator of protease production and sporulation. (206 aa)
BPUM_0981GntR family transcriptional regulator. (479 aa)
BPUM_1029Hypothetical protein; Belongs to the CvfB family. (282 aa)
BPUM_1122HxlR family transcriptional regulator. (112 aa)
BPUM_1126MarR family transcriptional regulator. (148 aa)
BPUM_1135LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (291 aa)
BPUM_1138LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (298 aa)
BPUM_1195PadR family transcriptional regulator. (108 aa)
hrcAHrcA family transcriptional regulator; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. (343 aa)
BPUM_2309RNA polymerase subunit sigma-70; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (247 aa)
BPUM_2330GntR family transcriptional regulator. (366 aa)
BPUM_2334HxlR family transcriptional regulator. (118 aa)
BPUM_2352LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (297 aa)
BPUM_2393Rrf2 family transcriptional regulator. (139 aa)
ruvBATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (334 aa)
BPUM_2429Transcriptional regulator. (180 aa)
BPUM_2494MarR family transcriptional regulator. (146 aa)
BPUM_2495LuxR family transcriptional regulator. (74 aa)
BPUM_2497LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (286 aa)
BPUM_2553Chemotaxis protein CheY. (242 aa)
BPUM_2572Hypothetical protein. (440 aa)
BPUM_2592PhoB family transcriptional regulator. (258 aa)
BPUM_2598Transcriptional regulator. (148 aa)
BPUM_2647Alkaline phosphatase. (73 aa)
BPUM_2662HxlR family transcriptional regulator. (123 aa)
BPUM_2677GntR family transcriptional regulator. (130 aa)
BPUM_2736Transcriptional regulator; Belongs to the GbsR family. (185 aa)
BPUM_2772Fis family transcriptional regulator; Positive regulatory protein that acts at the late promoter PL. (172 aa)
BPUM_2808AsnC family transcriptional regulator. (166 aa)
BPUM_2916DNA-binding response regulator. (231 aa)
BPUM_2921Transcriptional regulator. (310 aa)
BPUM_2953Transcriptional regulator. (225 aa)
BPUM_2989Transcriptional regulator. (240 aa)
BPUM_2998MarR family transcriptional regulator. (142 aa)
BPUM_3039MarR family transcriptional regulator. (106 aa)
BPUM_3044MarR family transcriptional regulator; Belongs to the GbsR family. (178 aa)
BPUM_3058Hypothetical protein. (345 aa)
BPUM_3062GntR family transcriptional regulator. (245 aa)
BPUM_3132Rrf2 family transcriptional regulator. (142 aa)
BPUM_3140Phosphonate metabolism transcriptional regulator PhnF. (241 aa)
BPUM_3155Transcriptional regulator. (228 aa)
BPUM_3162HxlR family transcriptional regulator. (121 aa)
BPUM_3270LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (298 aa)
BPUM_3273AsnC family transcriptional regulator. (158 aa)
BPUM_3292MarR family transcriptional regulator. (137 aa)
BPUM_3414Transcriptional regulator. (283 aa)
BPUM_3418AsnC family transcriptional regulator. (159 aa)
BPUM_3485LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (295 aa)
BPUM_3507PTS fructose transporter subunit IIA. (648 aa)
BPUM_3514RNA polymerase subunit sigma; Belongs to the sigma-70 factor family. ECF subfamily. (176 aa)
BPUM_3529HxlR family transcriptional regulator. (110 aa)
BPUM_3541Transcriptional regulator. (652 aa)
BPUM_3558RpiR family transcriptional regulator. (286 aa)
BPUM_3583MarR family transcriptional regulator. (147 aa)
BPUM_3594LuxR family transcriptional regulator. (335 aa)
BPUM_3603RpiR family transcriptional regulator. (285 aa)
BPUM_3611LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (299 aa)
BPUM_3647Transcriptional regulator. (183 aa)
BPUM_3663GntR family transcriptional regulator. (236 aa)
BPUM_3667LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (290 aa)
BPUM_3689PhoP family transcriptional regulator. (235 aa)
BPUM_3710RNA polymerase subunit sigma-70; Belongs to the sigma-70 factor family. ECF subfamily. (164 aa)
BPUM_2257Transcriptional repressor CcpN. (232 aa)
argRArginine repressor; Regulates arginine biosynthesis genes. (149 aa)
BPUM_2154Chemotaxis protein CheY; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. (267 aa)
BPUM_2117GntR family transcriptional regulator. (240 aa)
BPUM_2084Fur family transcriptional regulator; Belongs to the Fur family. (150 aa)
BPUM_2076RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (255 aa)
scpBSegregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (197 aa)
BPUM_2045Transcriptional regulator. (240 aa)
BPUM_2042RNA polymerase subunit sigma; Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in B. subtilis has been shown to regulate cell envelope modification and may effect antibiotic resistance; Belongs to the sigma-70 factor family. ECF subfamily. (202 aa)
birAbiotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. (327 aa)
BPUM_1967DNA replication protein DnaD. (234 aa)
BPUM_1902MarR family transcriptional regulator. (143 aa)
BPUM_1875HxlR family transcriptional regulator. (110 aa)
BPUM_1852ATP-dependent DNA helicase RecQ. (593 aa)
BPUM_1843ArsR family transcriptional regulator. (109 aa)
BPUM_1841Transcriptional regulator. (310 aa)
BPUM_1830XylR family transcriptional regulator. (386 aa)
BPUM_1815LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (300 aa)
BPUM_1789DNA-binding protein. (254 aa)
BPUM_1771RpiR family transcriptional regulator. (258 aa)
BPUM_1765MarR family transcriptional regulator. (139 aa)
sigARNA polymerase subunit sigma; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (373 aa)
BPUM_2241Fur family transcriptional regulator; Belongs to the Fur family. (142 aa)
mntRManganese transport transcriptional regulator; Central regulator of manganese homeostasis. Belongs to the DtxR/MntR family. (144 aa)
BPUM_1200Cysteine methyltransferase. (347 aa)
BPUM_1219PhoB family transcriptional regulator. (228 aa)
Your Current Organism:
Bacillus pumilus
NCBI taxonomy Id: 315750
Other names: B. pumilus SAFR-032, Bacillus pumilus SAFR-032, Bacillus pumilus str. SAFR-032, Bacillus pumilus strain SAFR-032
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