STRINGSTRING
RPE_0427 RPE_0427 RPE_0428 RPE_0428 RPE_0429 RPE_0429 RPE_0445 RPE_0445 RPE_0696 RPE_0696 RPE_0813 RPE_0813 RPE_0880 RPE_0880 lpxK lpxK RPE_1449 RPE_1449 RPE_1450 RPE_1450 RPE_1451 RPE_1451 hldD hldD hldE hldE RPE_2018 RPE_2018 lpxC lpxC lpxD lpxD RPE_2564 RPE_2564 RPE_2565 RPE_2565 lpxB lpxB lpxD-2 lpxD-2 kdsA kdsA RPE_2722 RPE_2722 RPE_2723 RPE_2723 RPE_2724 RPE_2724 RPE_2725 RPE_2725 RPE_2726 RPE_2726 RPE_2727 RPE_2727 RPE_3292 RPE_3292 RPE_3293 RPE_3293 lptD lptD kdsB kdsB RPE_4329 RPE_4329
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPE_0427KEGG: rpc:RPC_0418 hypothetical protein. (232 aa)
RPE_0428PFAM: OstA family protein; KEGG: rpc:RPC_0417 OstA-like protein. (229 aa)
RPE_0429PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rpd:RPD_0177 ABC transporter related. (314 aa)
RPE_0445PFAM: protein of unknown function DUF374; KEGG: rpc:RPC_0399 protein of unknown function DUF374. (223 aa)
RPE_0696KEGG: rpc:RPC_0769 KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. (337 aa)
RPE_0813PFAM: glycosyl transferase, group 1; KEGG: cvi:CV0817 probable glycosyltransferase. (397 aa)
RPE_0880Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (434 aa)
lpxKlipid-A-disaccharide synthase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (340 aa)
RPE_1449TIGRFAM: lipopolysaccharide heptosyltransferase I; PFAM: glycosyl transferase, family 9; KEGG: rpc:RPC_1428 lipopolysaccharide heptosyltransferase I. (314 aa)
RPE_1450D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase; TIGRFAM: histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; KEGG: rpc:RPC_1429 HAD-superfamily hydrolase subfamily IIIA. (177 aa)
RPE_1451TIGRFAM: lipopolysaccharide heptosyltransferase II; PFAM: glycosyl transferase, family 9; KEGG: rpc:RPC_1430 lipopolysaccharide heptosyltransferase II. (361 aa)
hldDADP-glyceromanno-heptose 6-epimerase precursor; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. (326 aa)
hldED-beta-D-heptose 1-phosphate adenylyltransferase; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family. (490 aa)
RPE_2018PFAM: lipid A biosynthesis acyltransferase; KEGG: rpc:RPC_2106 lipid A biosynthesis acyltransferase. (310 aa)
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (319 aa)
lpxDUDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (360 aa)
RPE_2564acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (277 aa)
RPE_2565PFAM: protein of unknown function DUF1009; KEGG: rpa:RPA2910 hypothetical protein. (284 aa)
lpxBlipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (391 aa)
lpxD-2UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (356 aa)
kdsATIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: rpc:RPC_2477 2-dehydro-3-deoxyphosphooctonate aldolase. (305 aa)
RPE_2722PFAM: alpha-2-macroglobulin domain protein; alpha-2-macroglobulin domain protein 2; KEGG: rpc:RPC_2542 alpha-2-macroglobulin-like. (1738 aa)
RPE_2723TIGRFAM: penicillin-binding protein 1C; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase; Penicillin-binding domain protein; KEGG: rpa:RPA2554 penicillin binding protein. (730 aa)
RPE_2724PFAM: glycosyl transferase, family 39; KEGG: rpc:RPC_2544 glycosyl transferase, family 39. (579 aa)
RPE_2725PFAM: phosphoesterase, PA-phosphatase related; KEGG: rpc:RPC_2545 phosphoesterase, PA-phosphatase related. (281 aa)
RPE_2726PFAM: glycosyl transferase, family 2; KEGG: rpc:RPC_2546 glycosyl transferase, family 2. (246 aa)
RPE_2727PFAM: lipid A biosynthesis domain protein; KEGG: rpb:RPB_2914 lipid A biosynthesis-like. (112 aa)
RPE_3292PFAM: permease YjgP/YjgQ family protein; KEGG: rpc:RPC_2313 permease YjgP/YjgQ. (388 aa)
RPE_3293PFAM: permease YjgP/YjgQ family protein; KEGG: rpc:RPC_2312 permease YjgP/YjgQ. (361 aa)
lptDOrganic solvent tolerance protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family. (827 aa)
kdsB3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (247 aa)
RPE_4329PFAM: glycosyl transferase, group 1; KEGG: rpc:RPC_1342 glycosyl transferase, group 1. (365 aa)
Your Current Organism:
Rhodopseudomonas palustris BisA53
NCBI taxonomy Id: 316055
Other names: R. palustris BisA53, Rhodopseudomonas palustris str. BisA53, Rhodopseudomonas palustris strain BisA53
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.