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| | RPC_0038 | Amine oxidase. (413 aa) |
| | acsA | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (647 aa) |
| | RPC_0068 | Succinate dehydrogenase subunit B; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (260 aa) |
| | RPC_0070 | Succinate dehydrogenase subunit A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (607 aa) |
| | RPC_0071 | Succinate dehydrogenase subunit D. (140 aa) |
| | RPC_0072 | Succinate dehydrogenase subunit C. (132 aa) |
| | RPC_0099 | Carboxylesterase; Serine hydrolase involved in the detoxification of formaldehyde. (281 aa) |
| | gfa | Glutathione-dependent formaldehyde-activating, GFA; Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione; Belongs to the Gfa family. (189 aa) |
| | RPC_0101 | Alcohol dehydrogenase, zinc-binding; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (369 aa) |
| | RPC_0104 | Succinate semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (491 aa) |
| | RPC_0132 | Branched chain amino acid: 2-keto-4-methylthiobutyrate aminotransferase. (301 aa) |
| | RPC_0183 | Dihydrolipoamide dehydrogenase. (467 aa) |
| | RPC_0190 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (434 aa) |
| | RPC_0191 | 2-oxoglutarate dehydrogenase E1 component. (991 aa) |
| | sucD | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa) |
| | sucC | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (399 aa) |
| | mdh1 | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (322 aa) |
| | RPC_0204 | Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (906 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (473 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (201 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. (378 aa) |
| | RPC_0254 | Acetyl-CoA hydrolase. (499 aa) |
| | gpmA | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (207 aa) |
| | accD | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (332 aa) |
| | RPC_0454 | Succinate semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (497 aa) |
| | accA | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (323 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (537 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (449 aa) |
| | RPC_0643 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (687 aa) |
| | RPC_0693 | Thiamine pyrophosphate enzyme-like TPP-binding; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (606 aa) |
| | RPC_0694 | Pyruvate ferredoxin/flavodoxin oxidoreductase. (307 aa) |
| | RPC_0695 | 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit. (386 aa) |
| | RPC_0696 | 2-oxoglutarate ferredoxin oxidoreductase, beta subunit. (280 aa) |
| | RPC_0697 | Pyruvate ferredoxin/flavodoxin oxidoreductase. (186 aa) |
| | RPC_0704 | Pyruvate flavodoxin/ferredoxin oxidoreductase-like. (1690 aa) |
| | RPC_0832 | Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa) |
| | ackA-2 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (414 aa) |
| | RPC_0834 | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (715 aa) |
| | RPC_0894 | Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (447 aa) |
| | RPC_1046 | 6-phosphogluconate dehydrogenase, NAD-binding. (292 aa) |
| | RPC_1055 | Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; Beta subunit of the biotin-dependent malonate decarboxylase multienzyme complex (EC 7.2.4.4). Acts as an integral membrane-bound carboxybiotin protein decarboxylase by releasing the carboxyl group of the carboxylated biotin carrier MADF. The free energy of the decarboxylation reaction is used to pump Na(+) out of the cell. (404 aa) |
| | ackA-3 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (414 aa) |
| | RPC_1079 | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (716 aa) |
| | RPC_1080 | Formate acetyltransferase. (759 aa) |
| | RPC_1081 | Pyruvate formate-lyase activating; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (267 aa) |
| | RPC_1163 | Pyruvate formate-lyase. (847 aa) |
| | RPC_1176 | Glycyl-radical enzyme activating. (306 aa) |
| | ackA-4 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (414 aa) |
| | RPC_1191 | Thiamine pyrophosphate enzyme-like TPP binding region; Belongs to the TPP enzyme family. (545 aa) |
| | RPC_1388 | Branched chain amino acid aminotransferase. (370 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (317 aa) |
| | RPC_1447 | L-threonine ammonia-lyase. (330 aa) |
| | RPC_1533 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (551 aa) |
| | gcvP | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (957 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (121 aa) |
| | RPC_1570 | Glycine cleavage system T protein. (384 aa) |
| | RPC_1576 | Isocitrate dehydrogenase (NADP); Belongs to the isocitrate and isopropylmalate dehydrogenases family. (407 aa) |
| | RPC_1602 | Aromatic amino acid beta-eliminating lyase/threonine aldolase. (371 aa) |
| | RPC_1614 | Ribulose-5-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (231 aa) |
| | RPC_1657 | Hypothetical protein. (125 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (929 aa) |
| | RPC_1693 | Acetolactate synthase, large subunit; Belongs to the TPP enzyme family. (541 aa) |
| | RPC_1892 | Citrate utilization protein B. (372 aa) |
| | RPC_1893 | Precorrin 3B synthase CobZ. (457 aa) |
| | RPC_1964 | Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (506 aa) |
| | RPC_1965 | Iron-containing alcohol dehydrogenase. (383 aa) |
| | ackA-5 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (414 aa) |
| | RPC_2007 | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (711 aa) |
| | RPC_2065 | 3-hydroxyisobutyrate dehydrogenase. (289 aa) |
| | rpiA | Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (232 aa) |
| | RPC_2089 | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (532 aa) |
| | RPC_2107 | Alcohol dehydrogenase, zinc-binding. (340 aa) |
| | RPC_2194 | Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa) |
| | RPC_2307 | Alcohol dehydrogenase, zinc-binding. (351 aa) |
| | RPC_2337 | Malate dehydrogenase (oxaloacetate decarboxylating) (NADP+)., Phosphate acetyltransferase. (769 aa) |
| | RPC_2420 | methylmalonyl-CoA epimerase. (134 aa) |
| | RPC_2450 | Citrate synthase; Belongs to the citrate synthase family. (434 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (257 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa) |
| | pdhA | Pyruvate dehydrogenase (lipoamide); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (347 aa) |
| | RPC_2490 | Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (465 aa) |
| | RPC_2492 | Dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (455 aa) |
| | RPC_2493 | Dihydrolipoamide dehydrogenase. (472 aa) |
| | ilvD | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. (574 aa) |
| | lipA | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (319 aa) |
| | RPC_2815 | Fructose-1,6-bisphosphatase, class II. (333 aa) |
| | RPC_2868 | Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (159 aa) |
| | RPC_2869 | Biotin carboxylase / acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (451 aa) |
| | RPC_2896 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (361 aa) |
| | RPC_2897 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (673 aa) |
| | fbp | D-fructose 1,6-bisphosphatase. (344 aa) |
| | RPC_2956 | Pyruvate kinase; Belongs to the pyruvate kinase family. (502 aa) |
| | RPC_2974 | Alcohol dehydrogenase, zinc-binding. (337 aa) |
| | RPC_2980 | Formate acetyltransferase. (758 aa) |
| | RPC_2981 | Pyruvate formate-lyase activating; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (267 aa) |
| | RPC_3090 | AMP-dependent synthetase and ligase. (576 aa) |
| | RPC_3095 | Methylmalonate-semialdehyde dehydrogenase (acylating). (498 aa) |
| | RPC_3100 | Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (388 aa) |
| | RPC_3191 | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. (566 aa) |
| | RPC_3193 | Aldehyde dehydrogenase. (476 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (521 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa) |
| | RPC_3253 | Acetolactate synthase, small subunit. (180 aa) |
| | RPC_3254 | Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (330 aa) |
| | RPC_3255 | Acetolactate synthase, large subunit. (593 aa) |
| | fumC | Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (472 aa) |
| | RPC_3276 | FAD linked oxidase-like. (472 aa) |
| | lipB | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (247 aa) |
| | RPC_3351 | 2,3-dimethylmalate lyase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family. (288 aa) |
| | RPC_3352 | Carbamoyl-phosphate synthase L chain, ATP-binding. (671 aa) |
| | RPC_3387 | Pyruvate ferredoxin/flavodoxin oxidoreductase. (1163 aa) |
| | RPC_3397 | Carboxyl transferase. (510 aa) |
| | RPC_3411 | Alcohol dehydrogenase GroES-like. (341 aa) |
| | RPC_3491 | Thiamine pyrophosphate enzyme-like TPP-binding. (529 aa) |
| | RPC_3493 | Succinate semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (483 aa) |
| | RPC_3494 | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (424 aa) |
| | RPC_3648 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (599 aa) |
| | tal | Glucose-6-phosphate isomerase / transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family. (950 aa) |
| | RPC_3671 | 6-phosphogluconate dehydrogenase (decarboxylating). (345 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (504 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (242 aa) |
| | RPC_3674 | Gluconate kinase. (180 aa) |
| | RPC_3675 | Cof protein. (270 aa) |
| | ackA-6 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (394 aa) |
| | RPC_3807 | Fructose-6-phosphate phosphoketolase. (784 aa) |
| | RPC_3878 | Transketolase subunit B. (342 aa) |
| | RPC_3879 | Transketolase subunit A. (279 aa) |
| | RPC_3982 | Pyruvate kinase; Belongs to the pyruvate kinase family. (475 aa) |
| | RPC_4115 | L-lactate dehydrogenase (cytochrome). (379 aa) |
| | purU | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (287 aa) |
| | RPC_4260 | Thiamine pyrophosphate enzyme-like TPP-binding. (512 aa) |
| | ilvD-2 | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. (612 aa) |
| | RPC_4337 | Alcohol dehydrogenase GroES-like. (329 aa) |
| | RPC_4343 | Pyruvate phosphate dikinase. (991 aa) |
| | RPC_4380 | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. (573 aa) |
| | RPC_4396 | AMP-dependent synthetase and ligase. (636 aa) |
| | RPC_4450 | Pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (402 aa) |
| | RPC_4481 | Iron-containing alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (884 aa) |
| | mdh2 | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa) |
| | RPC_4630 | Tartrate dehydrogenase. (357 aa) |
| | RPC_4689 | Aminotransferase, class V. (393 aa) |
| | RPC_4766 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (686 aa) |
| | RPC_4767 | Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (398 aa) |
| | RPC_4773 | Fructose-bisphosphate aldolase. (347 aa) |
| | RPC_4795 | L-threonine synthase. (492 aa) |
| | RPC_4893 | Alcohol dehydrogenase GroES-like. (351 aa) |
