Your Input: | |
| | RPC_4089 | Pyrimidine nucleoside phosphorylase-like. (513 aa) |
| | purH | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. (530 aa) |
| | RPC_0024 | Heparinase II/III-like. (592 aa) |
| | RPC_0034 | Metal dependent phosphohydrolase. (199 aa) |
| | acsA | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (647 aa) |
| | gpsA | Glycerol-3-phosphate dehydrogenase (NAD(P)+); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (329 aa) |
| | RPC_0060 | ErfK/YbiS/YcfS/YnhG. (171 aa) |
| | RPC_0135 | Hypothetical protein. (368 aa) |
| | rppH | NUDIX hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. (175 aa) |
| | RPC_0170 | NUDIX hydrolase. (178 aa) |
| | atpC | ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (135 aa) |
| | atpD | ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (476 aa) |
| | atpG | ATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (292 aa) |
| | atpA | ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (510 aa) |
| | atpH | ATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (203 aa) |
| | rlpA | Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (159 aa) |
| | RPC_0190 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (434 aa) |
| | RPC_0191 | 2-oxoglutarate dehydrogenase E1 component. (991 aa) |
| | RPC_0233 | Citryl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. (292 aa) |
| | RPC_0254 | Acetyl-CoA hydrolase. (499 aa) |
| | RPC_0268 | acyl-CoA thioesterase II. (291 aa) |
| | RPC_0281 | Conserved hypothetical protein. (199 aa) |
| | coaE | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (199 aa) |
| | RPC_0300 | MltA. (542 aa) |
| | coaA | Pantothenate kinase. (317 aa) |
| | pyrF | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (235 aa) |
| | gpmA | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (207 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (305 aa) |
| | RPC_0380 | Phosphopantothenoylcysteine decarboxylase / Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (475 aa) |
| | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (152 aa) |
| | RPC_0389 | FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. (447 aa) |
| | accD | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (332 aa) |
| | RPC_0394 | Conserved hypothetical protein. (130 aa) |
| | uppP | Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (268 aa) |
| | queG | 4Fe-4S ferredoxin, iron-sulfur binding; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (388 aa) |
| | RPC_0453 | Penicillin-binding protein 1A. (757 aa) |
| | murJ | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (537 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (429 aa) |
| | mtgA | Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (225 aa) |
| | RPC_0527 | Protein of unknown function DUF949. (477 aa) |
| | accA | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (323 aa) |
| | RPC_0592 | Conserved hypothetical protein. (516 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (449 aa) |
| | RPC_0662 | Conserved hypothetical protein. (115 aa) |
| | RPC_0664 | Protein involved in cellulose biosynthesis (CelD)-like. (326 aa) |
| | RPC_0665 | O-antigen polymerase. (436 aa) |
| | RPC_0667 | Polysaccharide biosynthesis protein. (476 aa) |
| | RPC_0672 | Conserved hypothetical protein. (408 aa) |
| | RPC_0675 | Glycosyl transferase, WecB/TagA/CpsF family; Belongs to the glycosyltransferase 26 family. (304 aa) |
| | RPC_0712 | Conserved hypothetical protein. (265 aa) |
| | RPC_0718 | Conserved hypothetical protein. (127 aa) |
| | RPC_0728 | Putative glycosyl transferases. (320 aa) |
| | RPC_0755 | Dihydroorotate oxidase A; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (364 aa) |
| | RPC_0765 | UDP-glucose pyrophosphorylase. (291 aa) |
| | RPC_0769 | KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. (337 aa) |
| | RPC_0788 | Protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. (213 aa) |
| | RPC_0793 | MltA-interacting MipA. (277 aa) |
| | ackA-2 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (414 aa) |
| | RPC_0848 | Xanthine dehydrogenase, molybdenum binding subunit apoprotein. (997 aa) |
| | queE | Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (210 aa) |
| | carA | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. (396 aa) |
| | RPC_1014 | 4-hydroxybenzoyl-CoA reductase alpha subunit. (778 aa) |
| | RPC_1016 | benzoate-CoA ligase. (521 aa) |
| | RPC_1025 | benzoate-CoA ligase. (524 aa) |
| | RPC_1043 | Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase. (295 aa) |
| | ackA-3 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (414 aa) |
| | RPC_1086 | ATPase FliI/YscN. (443 aa) |
| | RPC_1110 | Lytic transglycosylase, catalytic. (175 aa) |
| | RPC_1131 | Xanthine dehydrogenase, molybdenum binding subunit apoprotein. (750 aa) |
| | RPC_1141 | Phosphoglycerate mutase. (197 aa) |
| | dxs | 1-Deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (641 aa) |
| | RPC_1171 | Conserved hypothetical protein. (267 aa) |
| | ackA-4 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (414 aa) |
| | RPC_1246 | Conserved hypothetical protein. (168 aa) |
| | RPC_1255 | ErfK/YbiS/YcfS/YnhG. (329 aa) |
| | phnN | Phosphonate metabolism, 1,5-bisphosphokinase (PRPP-forming) PhnN; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). (192 aa) |
| | RPC_1341 | O-antigen polymerase. (466 aa) |
| | RPC_1361 | FAD dependent oxidoreductase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (516 aa) |
| | RPC_1399 | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. (323 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (317 aa) |
| | RPC_1428 | Lipopolysaccharide heptosyltransferase I. (327 aa) |
| | RPC_1429 | D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase. (176 aa) |
| | RPC_1430 | Lipopolysaccharide heptosyltransferase II. (359 aa) |
| | hldD | ADP-glyceromanno-heptose 6-epimerase precursor; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. (326 aa) |
| | hldE | D-alpha,beta-D-heptose 7-phosphate 1-kinase / D-beta-D-heptose 1-phosphate adenylyltransferase; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family. (490 aa) |
| | RPC_1433 | NAD-dependent epimerase/dehydratase. (327 aa) |
| | RPC_1435 | DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (382 aa) |
| | murJ-2 | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (509 aa) |
| | RPC_1439 | Xanthine dehydrogenase, molybdenum binding subunit apoprotein. (768 aa) |
| | RPC_1445 | Metallophosphoesterase. (266 aa) |
| | RPC_1525 | dCTP deaminase. (185 aa) |
| | purC-2 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (265 aa) |
| | purS | Phosphoribosylformylglycinamidine synthetase PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to ass [...] (82 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (233 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (736 aa) |
| | RPC_1600 | Appr-1-p processing. (180 aa) |
| | RPC_1604 | Conserved hypothetical protein. (258 aa) |
| | murI | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (265 aa) |
| | RPC_1610 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (435 aa) |
| | RPC_1614 | Ribulose-5-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (231 aa) |
| | RPC_1627 | 4Fe-4S ferredoxin, iron-sulfur binding. (233 aa) |
| | RPC_1646 | Glycosyl transferase, family 39. (496 aa) |
| | RPC_1657 | Hypothetical protein. (125 aa) |
| | RPC_1703 | Conserved hypothetical protein. (541 aa) |
| | RPC_1721 | Conserved hypothetical protein. (243 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (314 aa) |
| | RPC_1772 | Conserved hypothetical protein. (549 aa) |
| | RPC_1787 | Penicillin-binding protein 1A. (757 aa) |
| | RPC_1828 | Putative glycohydrolase. (269 aa) |
| | RPC_1895 | Phosphoglycerate mutase. (186 aa) |
| | RPC_1998 | MaoC-like dehydratase. (184 aa) |
| | ackA-5 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (414 aa) |
| | RPC_2032 | Lauroyl/myristoyl acyltransferase-like. (306 aa) |
| | rpiA | Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (232 aa) |
| | RPC_2106 | Lipid A biosynthesis acyltransferase. (310 aa) |
| | RPC_2110 | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ. (157 aa) |
| | RPC_2111 | Phosphopantetheine-binding. (94 aa) |
| | RPC_2129 | ErfK/YbiS/YcfS/YnhG. (408 aa) |
| | RPC_2171 | ErfK/YbiS/YcfS/YnhG. (236 aa) |
| | RPC_2185 | Negative regulator of AmpC, AmpD. (289 aa) |
| | murE | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (511 aa) |
| | murF | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (479 aa) |
| | mraY | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (361 aa) |
| | murD | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (466 aa) |
| | glpK | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (529 aa) |
| | pyrB | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (317 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (503 aa) |
| | mltG | Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (422 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (219 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (218 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase. (357 aa) |
| | RPC_2344 | ErfK/YbiS/YcfS/YnhG. (520 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (238 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (407 aa) |
| | lpxD1 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (358 aa) |
| | fabZ | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (151 aa) |
| | RPC_2447 | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (273 aa) |
| | RPC_2448 | Protein of unknown function DUF1009. (284 aa) |
| | lpxB | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (396 aa) |
| | lpxD2 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (373 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (257 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (543 aa) |
| | RPC_2476 | Conserved hypothetical protein. (291 aa) |
| | kdsA | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. (296 aa) |
| | queF | GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (158 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa) |
| | RPC_2490 | Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (465 aa) |
| | RPC_2492 | Dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (455 aa) |
| | RPC_2505 | Phosphoglycerate mutase. (191 aa) |
| | RPC_2507 | Deoxyguanosinetriphosphate triphosphohydrolase; Belongs to the dGTPase family. Type 2 subfamily. (404 aa) |
| | surE | 3'-nucleotidase / 5'-nucleotidase / exopolyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (255 aa) |
| | RPC_2543 | Penicillin-binding protein 1C. (696 aa) |
| | RPC_2544 | Glycosyl transferase, family 39. (581 aa) |
| | RPC_2547 | Lipid A biosynthesis-like. (112 aa) |
| | ispDF | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. (398 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (165 aa) |
| | queA | Queuosine biosynthesis protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (379 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (377 aa) |
| | glmU | UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the t [...] (458 aa) |
| | glmS | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (608 aa) |
| | RPC_2635 | (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (761 aa) |
| | RPC_2667 | Hypothetical protein. (333 aa) |
| | RPC_2684 | Lipopolysaccharide biosynthesis. (742 aa) |
| | RPC_2685 | Conserved hypothetical protein. (399 aa) |
| | rlpA-2 | Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (312 aa) |
| | RPC_2702 | Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. (418 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (230 aa) |
| | RPC_2737 | Protein of unknown function UPF0157. (187 aa) |
| | queC | ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (240 aa) |
| | RPC_2752 | MazG family protein. (274 aa) |
| | RPC_2832 | Conserved hypothetical protein. (155 aa) |
| | anmK | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (365 aa) |
| | RPC_2852 | Penicillin-binding protein 1A. (830 aa) |
| | RPC_2853 | N-acetylmuramoyl-L-alanine amidase. (431 aa) |
| | RPC_2869 | Biotin carboxylase / acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (451 aa) |
| | RPC_2890 | Lytic transglycosylase, catalytic. (747 aa) |
| | RPC_2897 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (673 aa) |
| | rlpA-3 | Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (162 aa) |
| | RPC_2909 | Lytic transglycosylase, catalytic. (262 aa) |
| | RPC_2956 | Pyruvate kinase; Belongs to the pyruvate kinase family. (502 aa) |
| | RPC_2976 | Conserved hypothetical protein. (286 aa) |
| | RPC_2995 | Lytic transglycosylase, catalytic. (287 aa) |
| | guaA | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (535 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (497 aa) |
| | RPC_3083 | Xanthine dehydrogenase, molybdenum binding subunit apoprotein. (792 aa) |
| | RPC_3090 | AMP-dependent synthetase and ligase. (576 aa) |
| | RPC_3120 | TPR repeat. (767 aa) |
| | RPC_3128 | Putative signal-transduction protein with CBS domains. (142 aa) |
| | gpt | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (174 aa) |
| | RPC_3238 | Polyphosphate:AMP phosphotransferase. (328 aa) |
| | RPC_3246 | Sulfatase. (568 aa) |
| | thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa) |
| | RPC_3286 | ErfK/YbiS/YcfS/YnhG. (251 aa) |
| | lpxC | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (319 aa) |
| | ddl | D-alanine--D-alanine ligase; Cell wall formation. (308 aa) |
| | murB | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. (308 aa) |
| | murC | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (467 aa) |
| | murG | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (375 aa) |
| | RPC_3321 | Lytic transglycosylase, catalytic. (341 aa) |
| | RPC_3323 | Conserved hypothetical protein. (597 aa) |
| | RPC_3328 | Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. (588 aa) |
| | RPC_3338 | Protein of unknown function DUF218. (264 aa) |
| | RPC_3408 | ErfK/YbiS/YcfS/YnhG. (496 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (335 aa) |
| | RPC_3454 | Conserved hypothetical protein. (379 aa) |
| | RPC_3479 | Phosphoglycerate mutase. (262 aa) |
| | queH | Protein of unknown function DUF208; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (206 aa) |
| | RPC_3513 | Thioesterase superfamily. (143 aa) |
| | RPC_3518 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (386 aa) |
| | RPC_3521 | Thioesterase superfamily. (139 aa) |
| | RPC_3545 | RelA/SpoT. (328 aa) |
| | tal | Glucose-6-phosphate isomerase / transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family. (950 aa) |
| | RPC_3671 | 6-phosphogluconate dehydrogenase (decarboxylating). (345 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (504 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (242 aa) |
| | RPC_3722 | Nucleoside diphosphate pyrophosphatase. (214 aa) |
| | kdsB | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (245 aa) |
| | RPC_3742 | Glycosyl transferase, family 39. (513 aa) |
| | ackA-6 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (394 aa) |
| | RPC_3820 | 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. (122 aa) |
| | carB | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. (1154 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (162 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (366 aa) |
| | RPC_3977 | Peptidoglycan-binding domain 1. (730 aa) |
| | RPC_3978 | Protein of unknown function DUF882. (541 aa) |
| | RPC_3982 | Pyruvate kinase; Belongs to the pyruvate kinase family. (475 aa) |
| | RPC_3984 | NAD-dependent epimerase/dehydratase. (293 aa) |
| | RPC_4025 | ErfK/YbiS/YcfS/YnhG. (253 aa) |
| | RPC_4073 | Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. (476 aa) |
| | ispH-2 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (320 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (430 aa) |
| | RPC_4156 | UDP-glucose 6-dehydrogenase. (438 aa) |
| | RPC_4162 | Glycosyl transferase, family 4. (352 aa) |
| | RPC_4163 | Polysaccharide biosynthesis protein CapD. (643 aa) |
| | purU | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (287 aa) |
| | RPC_4166 | NAD-dependent epimerase/dehydratase. (315 aa) |
| | RPC_4187 | dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (344 aa) |
| | RPC_4188 | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (291 aa) |
| | RPC_4195 | Glycosyl transferase, group 1. (873 aa) |
| | RPC_4198 | NAD-dependent epimerase/dehydratase. (345 aa) |
| | RPC_4199 | Glycosyl transferase, group 1. (368 aa) |
| | RPC_4203 | UDP-N-Acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (377 aa) |
| | RPC_4204 | Glycosyl transferase, group 1. (398 aa) |
| | RPC_4207 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (184 aa) |
| | RPC_4217 | NAD-dependent epimerase/dehydratase. (348 aa) |
| | RPC_4220 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (184 aa) |
| | RPC_4221 | NAD-dependent epimerase/dehydratase. (311 aa) |
| | RPC_4232 | ATPase FliI/YscN. (441 aa) |
| | RPC_4238 | Glycosyl transferase, family 2. (332 aa) |
| | RPC_4261 | ErfK/YbiS/YcfS/YnhG. (191 aa) |
| | RPC_4278 | Conserved hypothetical protein. (227 aa) |
| | RPC_4287 | 3-beta hydroxysteroid dehydrogenase/isomerase. (297 aa) |
| | RPC_4291 | ErfK/YbiS/YcfS/YnhG. (225 aa) |
| | RPC_4333 | Metal dependent phosphohydrolase. (205 aa) |
| | ispE | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (306 aa) |
| | RPC_4360 | Conserved hypothetical protein. (503 aa) |
| | RPC_4382 | Dihydrodipicolinate synthetase; Belongs to the DapA family. (303 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (199 aa) |
| | RPC_4396 | AMP-dependent synthetase and ligase. (636 aa) |
| | murA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (429 aa) |
| | RPC_4438 | Conserved hypothetical protein. (414 aa) |
| | RPC_4529 | Xanthine dehydrogenase, molybdenum binding subunit apoprotein. (786 aa) |
| | RPC_4590 | Malonate decarboxylase, beta subunit. (290 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. (427 aa) |
| | glk | Glucokinase; Belongs to the bacterial glucokinase family. (326 aa) |
| | RPC_4640 | Xanthine dehydrogenase, molybdenum binding subunit apoprotein. (756 aa) |
| | lpxK | lipid-A-disaccharide synthase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (343 aa) |
| | RPC_4705 | Three-deoxy-D-manno-octulosonic-acid transferase-like; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (434 aa) |
| | RPC_4722 | ErfK/YbiS/YcfS/YnhG. (265 aa) |
| | RPC_4766 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (686 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (398 aa) |
| | RPC_4773 | Fructose-bisphosphate aldolase. (347 aa) |
| | RPC_4804 | Cytidine deaminase. (141 aa) |
| | atpF1 | H+-transporting two-sector ATPase, B/B' subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (164 aa) |
| | atpF2 | H+-transporting two-sector ATPase, B/B' subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). (188 aa) |
| | atpE | H+-transporting two-sector ATPase, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (75 aa) |
| | atpB | ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (249 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (187 aa) |
| | RPC_4865 | Protein of unknown function DUF218. (240 aa) |
| | RPC_4888 | Glycosyl transferase, family 9. (331 aa) |
| | RPC_4903 | 2-deoxycytidine 5-triphosphate deaminase. (377 aa) |
| | RPC_4909 | ErfK/YbiS/YcfS/YnhG. (226 aa) |
| | mtnP | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (291 aa) |
