STRINGSTRING
RPB_0573 RPB_0573 RPB_0018 RPB_0018 RPB_0218 RPB_0218 mdh mdh gpsA gpsA RPB_0330 RPB_0330 leuB leuB RPB_3732 RPB_3732 RPB_1746 RPB_1746 RPB_1733 RPB_1733 RPB_1615 RPB_1615 RPB_1585 RPB_1585 RPB_1564 RPB_1564 RPB_1553 RPB_1553 RPB_1451 RPB_1451 RPB_3806 RPB_3806 RPB_3847 RPB_3847 RPB_3888 RPB_3888 RPB_4002 RPB_4002 RPB_4062 RPB_4062 RPB_4217 RPB_4217 RPB_4226 RPB_4226 hisD hisD RPB_4382 RPB_4382 RPB_4604 RPB_4604 RPB_4699 RPB_4699 RPB_3626 RPB_3626 RPB_3624 RPB_3624 RPB_3567 RPB_3567 RPB_3431 RPB_3431 RPB_3418 RPB_3418 RPB_3394 RPB_3394 ilvC ilvC RPB_3211 RPB_3211 guaB guaB RPB_3005 RPB_3005 RPB_2966 RPB_2966 dxr dxr RPB_2636 RPB_2636 RPB_2550 RPB_2550 RPB_2497 RPB_2497 pdxA pdxA RPB_2474 RPB_2474 RPB_2381 RPB_2381 RPB_2355 RPB_2355 RPB_2352 RPB_2352 RPB_2279 RPB_2279 RPB_2257 RPB_2257 RPB_2122 RPB_2122 RPB_2100 RPB_2100 murB murB RPB_1891 RPB_1891 zwf zwf RPB_1871 RPB_1871 RPB_1329 RPB_1329 RPB_1315 RPB_1315 RPB_1305 RPB_1305 aroE aroE RPB_1294 RPB_1294 RPB_0946 RPB_0946 RPB_0821 RPB_0821 RPB_0616 RPB_0616 RPB_0445 RPB_0445
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPB_0573D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (328 aa)
RPB_00182-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (306 aa)
RPB_02182-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (300 aa)
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (322 aa)
gpsAGlycerol-3-phosphate dehydrogenase (NAD(P)+); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (329 aa)
RPB_0330Short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (249 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. (370 aa)
RPB_3732Isocitrate dehydrogenase (NADP); Belongs to the isocitrate and isopropylmalate dehydrogenases family. (408 aa)
RPB_1746Short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (699 aa)
RPB_1733Glucose-methanol-choline oxidoreductase. (549 aa)
RPB_1615Cytochrome c, class I. (305 aa)
RPB_1585UDP-glucose 6-dehydrogenase. (435 aa)
RPB_1564dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (298 aa)
RPB_1553UDP-glucose/GDP-mannose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (423 aa)
RPB_1451FAD dependent oxidoreductase. (380 aa)
RPB_3806Alcohol dehydrogenase superfamily, zinc-containing. (351 aa)
RPB_3847Glucose-methanol-choline oxidoreductase. (534 aa)
RPB_38882-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (324 aa)
RPB_4002Chlorophyll synthesis pathway, bchC. (312 aa)
RPB_4062Glucose-methanol-choline oxidoreductase. (531 aa)
RPB_4217FAD dependent oxidoreductase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (513 aa)
RPB_4226D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (331 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (447 aa)
RPB_4382Glucose-methanol-choline oxidoreductase. (546 aa)
RPB_46043-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (738 aa)
RPB_4699Iron-containing alcohol dehydrogenase. (380 aa)
RPB_3626Tartrate dehydrogenase. (361 aa)
RPB_3624D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (304 aa)
RPB_3567Hydroxypyruvate reductase. (426 aa)
RPB_34312-dehydropantoate 2-reductase. (324 aa)
RPB_3418Alcohol dehydrogenase superfamily, zinc-containing; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (369 aa)
RPB_33943-hydroxyisobutyrate dehydrogenase. (289 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa)
RPB_3211Quinoprotein glucose dehydrogenase. (837 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (498 aa)
RPB_30053-hydroxyisobutyrate dehydrogenase. (295 aa)
RPB_2966Homoserine dehydrogenase. (440 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (407 aa)
RPB_2636Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (389 aa)
RPB_2550D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (329 aa)
RPB_2497Bifunctional oxaloacetate decarboxylating malate dehydrogenase (NADP+)/phosphate acetyltransferase. (769 aa)
pdxA4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (334 aa)
RPB_2474Alcohol dehydrogenase, zinc-containing. (352 aa)
RPB_2381Aldo/keto reductase. (272 aa)
RPB_2355Pyrrolo-quinoline quinone. (730 aa)
RPB_2352MaoC-like dehydratase. (286 aa)
RPB_2279D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (315 aa)
RPB_2257D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (336 aa)
RPB_21223-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (295 aa)
RPB_2100NAD-dependent epimerase/dehydratase. (328 aa)
murBUDP-N-acetylmuramate dehydrogenase; Cell wall formation. (309 aa)
RPB_18916-phosphogluconate dehydrogenase (decarboxylating). (345 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (504 aa)
RPB_1871Alcohol dehydrogenase superfamily, zinc-containing. (350 aa)
RPB_1329Aldo/keto reductase. (274 aa)
RPB_1315D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (529 aa)
RPB_1305L-lactate dehydrogenase (cytochrome). (379 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (280 aa)
RPB_1294Glucose sorbosone dehydrogenase. (391 aa)
RPB_0946Iron-containing alcohol dehydrogenase. (395 aa)
RPB_08213-hydroxyacyl-CoA dehydrogenase. (293 aa)
RPB_0616Glycolate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (333 aa)
RPB_0445Glycoside hydrolase, family 4. (426 aa)
Your Current Organism:
Rhodopseudomonas palustris HaA2
NCBI taxonomy Id: 316058
Other names: R. palustris HaA2, Rhodopseudomonas palustris str. HaA2, Rhodopseudomonas palustris strain HaA2
Server load: low (24%) [HD]