STRINGSTRING
RPB_3520 RPB_3520 dnaA dnaA recF recF rpmI rpmI RPB_0096 RPB_0096 rplU rplU rpmA rpmA priA priA RPB_0295 RPB_0295 RPB_0300 RPB_0300 rpsP rpsP RPB_0388 RPB_0388 dnaQ dnaQ nth nth RPB_0440 RPB_0440 rpmF rpmF RPB_0541 RPB_0541 RPB_0542 RPB_0542 rpmB rpmB infB infB rpsO rpsO ihfB ihfB RPB_0640 RPB_0640 hpf hpf recR recR RPB_0667 RPB_0667 rpmH rpmH RPB_0700 RPB_0700 RPB_0786 RPB_0786 RPB_0818 RPB_0818 cbbM cbbM ackA ackA smc smc RPB_1073 RPB_1073 RPB_1130 RPB_1130 RPB_1218 RPB_1218 RPB_1320 RPB_1320 rpmJ rpmJ rpsU rpsU RPB_1504 RPB_1504 RPB_1534 RPB_1534 RPB_1652 RPB_1652 RPB_1680 RPB_1680 RPB_1719 RPB_1719 RPB_1726 RPB_1726 RPB_1778 RPB_1778 RPB_1793 RPB_1793 RPB_1811 RPB_1811 RPB_1834 RPB_1834 RPB_1874 RPB_1874 RPB_2007 RPB_2007 RPB_2014 RPB_2014 RPB_2197 RPB_2197 RPB_2255 RPB_2255 rplJ rplJ rplL rplL rpsL rpsL rpsG rpsG rpsJ rpsJ rplC rplC rplD rplD rplW rplW rplB rplB rpsS rpsS rplV rplV rpsC rpsC rplP rplP rpmC rpmC rpsQ rpsQ rplN rplN rplX rplX rplE rplE rpsN rpsN rpsH rpsH rplF rplF rplR rplR rpsE rpsE rpmD rpmD rplO rplO rpsK rpsK rplQ rplQ RPB_2324 RPB_2324 RPB_2326 RPB_2326 RPB_2363 RPB_2363 rpmG rpmG RPB_2458 RPB_2458 rplI rplI rpsR rpsR rpsF rpsF RPB_2491 RPB_2491 RPB_2529 RPB_2529 RPB_2570 RPB_2570 recO recO RPB_2629 RPB_2629 ihfA ihfA rplM rplM rpsI rpsI RPB_2723 RPB_2723 RPB_2725 RPB_2725 RPB_2802 RPB_2802 rpsB rpsB cobB cobB RPB_2985 RPB_2985 RPB_2987 RPB_2987 RPB_3028 RPB_3028 RPB_3043 RPB_3043 RPB_3140 RPB_3140 guaB guaB RPB_3227 RPB_3227 RPB_3311 RPB_3311 RPB_3385 RPB_3385 RPB_3444 RPB_3444 RPB_3445 RPB_3445 RPB_3519 RPB_3519 RPB_3521 RPB_3521 RPB_3537 RPB_3537 rpsD rpsD RPB_3780 RPB_3780 RPB_3801 RPB_3801 RPB_3807 RPB_3807 RPB_3860 RPB_3860 RPB_3889 RPB_3889 RPB_3955 RPB_3955 RPB_3963 RPB_3963 cbbL cbbL RPB_4005 RPB_4005 RPB_4011 RPB_4011 dnaG dnaG RPB_4136 RPB_4136 rplY rplY rpmE rpmE RPB_4701 RPB_4701 rpsT rpsT
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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RPB_3520Conserved hypothetical protein. (313 aa)
dnaAChromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. (472 aa)
recFDNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (378 aa)
rpmILSU ribosomal protein L35P; Belongs to the bacterial ribosomal protein bL35 family. (66 aa)
RPB_0096FAD dependent oxidoreductase. (722 aa)
rplULSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (128 aa)
rpmALSU ribosomal protein L27P; Belongs to the bacterial ribosomal protein bL27 family. (89 aa)
priAReplication restart DNA helicase PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (735 aa)
RPB_0295Peptidase S16, lon-like. (224 aa)
RPB_0300Ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit; Belongs to the RuBisCO large chain family. (431 aa)
rpsPSSU ribosomal protein S16P; Belongs to the bacterial ribosomal protein bS16 family. (110 aa)
RPB_0388Chromosome segregation DNA-binding protein; Belongs to the ParB family. (296 aa)
dnaQDNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (231 aa)
nthEndonuclease III / DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (254 aa)
RPB_0440Peptidase S10, serine carboxypeptidase. (505 aa)
rpmFLSU ribosomal protein L32P; Belongs to the bacterial ribosomal protein bL32 family. (60 aa)
RPB_0541Hydrogenobyrinic acid a,c-diamide cobaltochelatase. (331 aa)
RPB_0542Protein of unknown function DUF29. (166 aa)
rpmBLSU ribosomal protein L28P; Belongs to the bacterial ribosomal protein bL28 family. (101 aa)
infBBacterial translation initiation factor 2 (bIF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (886 aa)
rpsOSSU ribosomal protein S15P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. (89 aa)
ihfBIntegration host factor, beta subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (101 aa)
RPB_0640SSU ribosomal protein S1P; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. (565 aa)
hpfSSU ribosomal protein S30P / sigma 54 modulation protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. (202 aa)
recRDNA replication and repair protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (201 aa)
RPB_0667Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. (106 aa)
rpmHLSU ribosomal protein L34P; Belongs to the bacterial ribosomal protein bL34 family. (44 aa)
RPB_0700DNA repair protein RadC; Belongs to the UPF0758 family. (250 aa)
RPB_0786Hypothetical protein. (565 aa)
RPB_0818ATP:cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (190 aa)
cbbMRibulose-1,5-bisphosphate carboxylase/oxygenase large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site; Belongs to the RuBisCO large chain family. Type II subfamily. (461 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa)
smcCondensin subunit Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1154 aa)
RPB_1073DNA adenine methylase CcrM; Belongs to the N(4)/N(6)-methyltransferase family. (377 aa)
RPB_1130Protein of unknown function DUF159; Belongs to the SOS response-associated peptidase family. (259 aa)
RPB_1218Conserved hypothetical protein. (369 aa)
RPB_1320Conserved hypothetical protein. (345 aa)
rpmJLSU ribosomal protein L36P; Belongs to the bacterial ribosomal protein bL36 family. (41 aa)
rpsUSSU ribosomal protein S21P; Belongs to the bacterial ribosomal protein bS21 family. (101 aa)
RPB_1504Conserved hypothetical protein. (193 aa)
RPB_1534N-acetylneuraminate synthase. (332 aa)
RPB_1652Class II aldolase/adducin-like. (257 aa)
RPB_1680Conserved hypothetical protein. (281 aa)
RPB_1719Ethanolamine ammonia-lyase light chain; Belongs to the EutC family. (259 aa)
RPB_1726Squalene cyclase. (654 aa)
RPB_1778TPR repeat protein. (269 aa)
RPB_1793DEAD/DEAH box helicase; Belongs to the DEAD box helicase family. (491 aa)
RPB_1811Putative TolA. (320 aa)
RPB_1834FAD dependent oxidoreductase. (504 aa)
RPB_1874Conserved hypothetical protein. (118 aa)
RPB_2007DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (561 aa)
RPB_2014FAD dependent oxidoreductase. (552 aa)
RPB_2197TPR repeat protein. (178 aa)
RPB_2255Conserved hypothetical protein. (186 aa)
rplJLSU ribosomal protein L10P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (172 aa)
rplLLSU ribosomal protein L12P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (123 aa)
rpsLSSU ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. (123 aa)
rpsGSSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
rpsJSSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
rplCLSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (241 aa)
rplDLSU ribosomal protein L4P; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (206 aa)
rplWLSU ribosomal protein L23P; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (99 aa)
rplBLSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (278 aa)
rpsSSSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa)
rplVLSU ribosomal protein L22P; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). (128 aa)
rpsCSSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (232 aa)
rplPLSU ribosomal protein L16P; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (137 aa)
rpmCLSU ribosomal protein L29P; Belongs to the universal ribosomal protein uL29 family. (69 aa)
rpsQSSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (82 aa)
rplNLSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa)
rplXLSU ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (104 aa)
rplELSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (185 aa)
rpsNSSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa)
rpsHSSU ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa)
rplFLSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa)
rplRLSU ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (120 aa)
rpsESSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. (191 aa)
rpmDLSU ribosomal protein L30P. (64 aa)
rplOLSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (161 aa)
rpsKSSU ribosomal protein S11P; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (129 aa)
rplQLSU ribosomal protein L17P. (138 aa)
RPB_2324Recombination protein MgsA. (444 aa)
RPB_2326Conserved hypothetical protein. (245 aa)
RPB_2363Conserved hypothetical protein. (119 aa)
rpmGLSU ribosomal protein L33P; Belongs to the bacterial ribosomal protein bL33 family. (55 aa)
RPB_2458Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (498 aa)
rplILSU ribosomal protein L9P; Binds to the 23S rRNA. (196 aa)
rpsRSSU ribosomal protein S18P; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (79 aa)
rpsFSSU ribosomal protein S6P; Binds together with S18 to 16S ribosomal RNA. (159 aa)
RPB_2491Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. (225 aa)
RPB_2529Hypothetical protein. (403 aa)
RPB_2570Histone-like DNA-binding protein; Belongs to the bacterial histone-like protein family. (103 aa)
recODNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination. (249 aa)
RPB_2629Conserved hypothetical protein. (185 aa)
ihfAIntegration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (123 aa)
rplMLSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (154 aa)
rpsISSU ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (158 aa)
RPB_2723TPR repeat protein. (342 aa)
RPB_2725Conserved hypothetical protein. (127 aa)
RPB_2802Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. (167 aa)
rpsBSSU ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. (331 aa)
cobBSilent information regulator protein Sir2; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. (253 aa)
RPB_2985DEAD/DEAH box helicase; Belongs to the DEAD box helicase family. (516 aa)
RPB_2987TfoX-like. (133 aa)
RPB_3028Esterase/lipase/thioesterase. (314 aa)
RPB_3043ADP-ribosyl-(dinitrogen reductase) hydrolase. (298 aa)
RPB_3140Conserved hypothetical protein. (296 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (498 aa)
RPB_3227Ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit. (367 aa)
RPB_3311Hypothetical protein. (1082 aa)
RPB_3385Conserved hypothetical protein. (169 aa)
RPB_3444Ferredoxin. (301 aa)
RPB_3445Rubrerythrin. (162 aa)
RPB_3519Transcriptional regulator, MucR family. (139 aa)
RPB_3521Class II aldolase/adducin-like. (259 aa)
RPB_3537Glutathione-dependent formaldehyde-activating, GFA. (154 aa)
rpsDSSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (205 aa)
RPB_3780Conserved hypothetical protein. (1306 aa)
RPB_3801TPR repeat protein. (713 aa)
RPB_3807Acetoin dehydrogenase (TPP-dependent) beta chain. (350 aa)
RPB_3860Serine/threonine protein kinase. (486 aa)
RPB_3889Class II aldolase/adducin-like. (250 aa)
RPB_3955Protein of unknown function DUF477. (302 aa)
RPB_3963Ribulose 1,5-bisphosphate carboxylase small subunit. (140 aa)
cbbLRibulose-1,5-bisphosphate carboxylase/oxygenase large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site; Belongs to the RuBisCO large chain family. Type I subfamily. (485 aa)
RPB_4005FAD dependent oxidoreductase. (516 aa)
RPB_4011Amine oxidase. (511 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. (683 aa)
RPB_4136N-formylglutamate amidohydrolase. (249 aa)
rplYLSU ribosomal protein L25P; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (240 aa)
rpmELSU ribosomal protein L31P; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. (75 aa)
RPB_4701ATP-dependent DNA helicase RecQ. (618 aa)
rpsTSSU ribosomal protein S20P; Binds directly to 16S ribosomal RNA. (88 aa)
Your Current Organism:
Rhodopseudomonas palustris HaA2
NCBI taxonomy Id: 316058
Other names: R. palustris HaA2, Rhodopseudomonas palustris str. HaA2, Rhodopseudomonas palustris strain HaA2
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