(19 nodes) Peptidoglycan biosynthesis network (Rhodopseudomonas palustris HaA2)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Predicted Interactions

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protein homology

Your Input:
	RPB_0041	Penicillin-binding protein 1A. (735 aa)
	mtgA	Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (227 aa)
	uppP	Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (268 aa)
	RPB_1988	Peptidoglycan glycosyltransferase. (584 aa)
	murE	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (485 aa)
	murF	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (479 aa)
	mraY	Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (361 aa)
	murD	UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (466 aa)
	murG	Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (366 aa)
	murC	UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (468 aa)
	murB	UDP-N-acetylmuramate dehydrogenase; Cell wall formation. (309 aa)
	RPB_2001	D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (329 aa)
	RPB_2678	Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. (419 aa)
	RPB_2688	Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (239 aa)
	RPB_2824	Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (252 aa)
	RPB_2918	Penicillin-binding protein 1C. (731 aa)
	RPB_3007	Penicillin-binding protein 1A. (830 aa)
	RPB_3506	Penicillin-binding protein 1A. (769 aa)
	murA	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (429 aa)

Your Current Organism:

Rhodopseudomonas palustris HaA2

NCBI taxonomy Id: 316058
Other names: R. palustris HaA2, Rhodopseudomonas palustris str. HaA2, Rhodopseudomonas palustris strain HaA2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RPB_0041	RPB_1988	RPB_0041	RPB_1988	Penicillin-binding protein 1A.	Peptidoglycan glycosyltransferase.	0.856
RPB_0041	RPB_2001	RPB_0041	RPB_2001	Penicillin-binding protein 1A.	D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.	0.581
RPB_0041	RPB_2678	RPB_0041	RPB_2678	Penicillin-binding protein 1A.	Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family.	0.912
RPB_0041	RPB_3007	RPB_0041	RPB_3007	Penicillin-binding protein 1A.	Penicillin-binding protein 1A.	0.945
RPB_0041	RPB_3506	RPB_0041	RPB_3506	Penicillin-binding protein 1A.	Penicillin-binding protein 1A.	0.913
RPB_0041	mraY	RPB_0041	RPB_1991	Penicillin-binding protein 1A.	Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.	0.471
RPB_0041	murA	RPB_0041	RPB_4352	Penicillin-binding protein 1A.	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.	0.604
RPB_0041	murC	RPB_0041	RPB_1996	Penicillin-binding protein 1A.	UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.	0.632
RPB_0041	murD	RPB_0041	RPB_1992	Penicillin-binding protein 1A.	UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.	0.486
RPB_0041	murE	RPB_0041	RPB_1989	Penicillin-binding protein 1A.	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.	0.511
RPB_0041	murF	RPB_0041	RPB_1990	Penicillin-binding protein 1A.	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.	0.520
RPB_0041	murG	RPB_0041	RPB_1994	Penicillin-binding protein 1A.	Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.	0.691
RPB_1988	RPB_0041	RPB_1988	RPB_0041	Peptidoglycan glycosyltransferase.	Penicillin-binding protein 1A.	0.856
RPB_1988	RPB_2001	RPB_1988	RPB_2001	Peptidoglycan glycosyltransferase.	D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.	0.772
RPB_1988	RPB_2678	RPB_1988	RPB_2678	Peptidoglycan glycosyltransferase.	Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family.	0.745
RPB_1988	RPB_3007	RPB_1988	RPB_3007	Peptidoglycan glycosyltransferase.	Penicillin-binding protein 1A.	0.802
RPB_1988	RPB_3506	RPB_1988	RPB_3506	Peptidoglycan glycosyltransferase.	Penicillin-binding protein 1A.	0.867
RPB_1988	mraY	RPB_1988	RPB_1991	Peptidoglycan glycosyltransferase.	Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.	0.815
RPB_1988	mtgA	RPB_1988	RPB_0515	Peptidoglycan glycosyltransferase.	Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.	0.608
RPB_1988	murA	RPB_1988	RPB_4352	Peptidoglycan glycosyltransferase.	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.	0.670