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RPB_0274 RPB_0274 sucD sucD sucC sucC acsA acsA RPB_0509 RPB_0509 accA accA RPB_0579 RPB_0579 accD accD RPB_0701 RPB_0701 RPB_0704 RPB_0704 RPB_1026 RPB_1026 ackA ackA RPB_1108 RPB_1108 RPB_1184 RPB_1184 RPB_1240 RPB_1240 RPB_1682 RPB_1682 RPB_1748 RPB_1748 RPB_2101 RPB_2101 RPB_2107 RPB_2107 RPB_2117 RPB_2117 RPB_2121 RPB_2121 RPB_2123 RPB_2123 RPB_2342 RPB_2342 RPB_2350 RPB_2350 RPB_2367 RPB_2367 RPB_2590 RPB_2590 RPB_2766 RPB_2766 RPB_3019 RPB_3019 RPB_3020 RPB_3020 RPB_3137 RPB_3137 RPB_3536 RPB_3536 RPB_3538 RPB_3538 RPB_3557 RPB_3557 RPB_3607 RPB_3607 RPB_4151 RPB_4151 RPB_4326 RPB_4326 RPB_4604 RPB_4604 RPB_4605 RPB_4605
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
RPB_0274Dihydrolipoamide dehydrogenase. (467 aa)
sucDsuccinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa)
sucCsuccinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (398 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (652 aa)
RPB_0509acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
accAAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (320 aa)
RPB_0579Beta-lactamase. (395 aa)
accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (322 aa)
RPB_0701Enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (261 aa)
RPB_0704Malonyl-CoA decarboxylase. (473 aa)
RPB_1026Phosphate butyryltransferase. (472 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa)
RPB_1108Alcohol dehydrogenase superfamily, zinc-containing. (328 aa)
RPB_1184Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (448 aa)
RPB_1240Enoyl-CoA hydratase. (282 aa)
RPB_1682Acetyl-CoA C-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
RPB_1748Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
RPB_2101Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa)
RPB_2107CoA-binding. (702 aa)
RPB_2117Methylmalonate-semialdehyde dehydrogenase (acylating). (498 aa)
RPB_2121Enoyl-CoA hydratase/isomerase. (357 aa)
RPB_2123AMP-dependent synthetase and ligase. (572 aa)
RPB_2342Carboxyl transferase. (510 aa)
RPB_2350Thiolase. (382 aa)
RPB_2367Carbamoyl-phosphate synthase L chain, ATP-binding. (671 aa)
RPB_2590methylmalonyl-CoA epimerase. (134 aa)
RPB_2766Dihydrolipoamide dehydrogenase. (473 aa)
RPB_3019Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (170 aa)
RPB_3020Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha / biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (451 aa)
RPB_31374-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (424 aa)
RPB_3536Methylmalonyl-CoA mutase. (623 aa)
RPB_3538methylmalonyl-CoA mutase. (736 aa)
RPB_3557Short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (259 aa)
RPB_3607acetyl-CoA acetyltransferase. (503 aa)
RPB_4151Acetyl-CoA C-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (417 aa)
RPB_4326AMP-dependent synthetase and ligase. (636 aa)
RPB_46043-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (738 aa)
RPB_4605Acetyl-CoA C-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
Your Current Organism:
Rhodopseudomonas palustris HaA2
NCBI taxonomy Id: 316058
Other names: R. palustris HaA2, Rhodopseudomonas palustris str. HaA2, Rhodopseudomonas palustris strain HaA2
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