STRINGSTRING
CAK27295.1 CAK27295.1 CAK27296.1 CAK27296.1 CAK27297.1 CAK27297.1 CAK27298.1 CAK27298.1 CAK27345.1 CAK27345.1 CAK27350.1 CAK27350.1 masA masA mtnB mtnB mutM mutM mtnD mtnD CAK27364.1 CAK27364.1 mtnP mtnP CAK28911.1 CAK28911.1 fucA fucA CAK28914.1 CAK28914.1 mtnA mtnA gltS gltS CAK28996.1 CAK28996.1 speH speH coaE coaE speE speE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CAK27295.1Peroxiredoxin; Posttranslational modification, protein turnover, chaperones. (156 aa)
CAK27296.14'-phosphopantetheinyl transferase related protein. (219 aa)
CAK27297.1Conserved hypothetical protein. (173 aa)
CAK27298.1Uncharacterized conserved secreted protein. (215 aa)
CAK27345.1Hydrolase, haloacid dehalogenase-like. (219 aa)
CAK27350.1Neutral invertase-like protein; Carbohydrate transport and metabolism. (517 aa)
masAPutative enolase-phosphatase E-1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. (249 aa)
mtnBSugar aldolase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. (226 aa)
mutMFormamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (282 aa)
mtnDARD/ARD' family protein (methionine salvage pathway); Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. (185 aa)
CAK27364.1Conserved hypothetical protein. (106 aa)
mtnP5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (313 aa)
CAK28911.1Conserved hypothetical protein. (123 aa)
fucAPossible L-fuculose phosphate aldolase; Carbohydrate transport and metabolism. (224 aa)
CAK28914.1Conserved hypothetical protein. (158 aa)
mtnAPredicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (363 aa)
gltSPutative Na+/glutamate symporter; Amino acid transport and metabolism. (492 aa)
CAK28996.1Uncharacterized membrane protein. (65 aa)
speHS-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. (130 aa)
coaEDephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (213 aa)
speESpermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (282 aa)
Your Current Organism:
Synechococcus sp. RCC307
NCBI taxonomy Id: 316278
Other names: S. sp. RCC307, Synechococcus sp. MINSyn016-15m-01 substr. AC6A1
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.