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DFI_05685 DFI_05685 DFI_04820 DFI_04820 lysK lysK DFI_03025 DFI_03025 DFI_02270 DFI_02270 DFI_13440 DFI_13440 argB argB DFI_11400 DFI_11400 DFI_11390 DFI_11390 asd asd DFI_09345 DFI_09345 leuC leuC leuD leuD leuB leuB lysJ lysJ leuA leuA ilvC ilvC DFI_08390 DFI_08390 DFI_08385 DFI_08385 DFI_08260 DFI_08260 DFI_07960 DFI_07960 lysY lysY lysZ lysZ ilvD ilvD argJ argJ DFI_07095 DFI_07095 leuC-2 leuC-2 DFI_07070 DFI_07070 DFI_07055 DFI_07055 DFI_06940 DFI_06940 argC argC DFI_16090 DFI_16090
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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DFI_05685Isocitrate dehydrogenase. (333 aa)
DFI_04820Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (904 aa)
lysK[LysW]-lysine hydrolase; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine. (376 aa)
DFI_03025Citrate synthase; Belongs to the citrate synthase family. (377 aa)
DFI_022702-aminoadipate aminotransferase. (382 aa)
DFI_13440GNAT family N-acetyltransferase. (177 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (249 aa)
DFI_11400Citrate synthase. (411 aa)
DFI_11390Pyruvate carboxyltransferase. (431 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (339 aa)
DFI_09345Homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (390 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (428 aa)
leuD3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (162 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (351 aa)
lysJ[LysW]-aminoadipate semialdehyde transaminase; Catalyzes the transfer of the amino group of L-glutamate to [LysW]-aminoadipate 6-semialdehyde, generating [LysW]-gamma-L-lysine. Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. (416 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (521 aa)
ilvCKetol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (336 aa)
DFI_08390Acetolactate synthase small subunit. (207 aa)
DFI_08385Acetolactate synthase. (574 aa)
DFI_08260Aminotransferase. (393 aa)
DFI_07960Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (354 aa)
lysY[LysW]-L-2-aminoadipate 6-phosphate reductase; Catalyzes the NADPH-dependent reduction of [LysW]- aminoadipate 6-phosphate to yield [LysW]-aminoadipate 6-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. (347 aa)
lysZ[LysW]-aminoadipate kinase; Catalyzes the phosphorylation of LysW-gamma-alpha- aminoadipate; Belongs to the acetylglutamate kinase family. LysZ subfamily. (267 aa)
ilvDDihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (576 aa)
argJArginine biosynthesis bifunctional protein ArgJ alpha chain; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (401 aa)
DFI_07095Isocitrate dehydrogenase [NADP]. (416 aa)
leuC-23-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (422 aa)
DFI_07070Homoaconitate hydratase; Belongs to the LeuD family. (167 aa)
DFI_07055Lysine biosynthesis enzyme LysX; Belongs to the RimK family. (288 aa)
DFI_06940Aspartokinase; Belongs to the aspartokinase family. (475 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (311 aa)
DFI_16090Acetylornithine deacetylase. (377 aa)
Your Current Organism:
Deinococcus ficus
NCBI taxonomy Id: 317577
Other names: CCUG 51391, CIP 108832, D. ficus, DSM 17424 [[Deinococcus mumbaiensis Shashidhar and Bandekar 2006]], DSM 19119, Deinococcus ficus Lai et al. 2006 emend. Kampfer 2009, Deinococcus mumbaiensis, Deinococcus mumbaiensis Shashidhar and Bandekar 2006, Deinococcus sp. 2009, Deinococcus sp. CC-FR2-10, Deinococcus sp. UK, MTCC 7297 [[Deinococcus mumbaiensis Shashidhar and Bandekar 2006]], strain CC-FR2-10, strain CON-1 [[Deinococcus mumbaiensis Shashidhar and Bandekar 2006]]
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