STRINGSTRING
Pden_0567 Pden_0567 Pden_0568 Pden_0568 Pden_0569 Pden_0569 Pden_0572 Pden_0572 ppk ppk Pden_1594 Pden_1594 Pden_1835 Pden_1835 ccoP ccoP Pden_1846 Pden_1846 Pden_1847 Pden_1847 Pden_1848 Pden_1848 Pden_1938 Pden_1938 nuoN nuoN Pden_2232 Pden_2232 Pden_2233 Pden_2233 nuoK nuoK Pden_2235 Pden_2235 nuoI nuoI nuoH nuoH Pden_2241 Pden_2241 Pden_2243 Pden_2243 Pden_2246 Pden_2246 nuoD nuoD nuoC nuoC nuoB nuoB nuoA nuoA Pden_2305 Pden_2305 Pden_2306 Pden_2306 Pden_2307 Pden_2307 atpF atpF atpF-2 atpF-2 atpE atpE atpB atpB Pden_3020 Pden_3020 Pden_3021 Pden_3021 Pden_3022 Pden_3022 Pden_3028 Pden_3028 Pden_3659 Pden_3659 ctaA ctaA Pden_3709 Pden_3709 atpH atpH atpA atpA atpG atpG atpD atpD atpC atpC Pden_4010 Pden_4010 Pden_4011 Pden_4011 Pden_4317 Pden_4317 ctaG ctaG ctaB ctaB Pden_4321 Pden_4321 Pden_4500 Pden_4500
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Pden_0567PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: rsp:RSP_0974 succinate dehydrogenase cytochrome b-556 subunit. (130 aa)
Pden_0568KEGG: rsp:RSP_0975 putative succinate dehydrogenase, hydrophobic membrane anchor protein. (129 aa)
Pden_0569KEGG: rsp:RSP_0976 succinate dehydrogenase; TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (600 aa)
Pden_0572TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: rde:RD1_1630 succinate dehydrogenase, iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (259 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (721 aa)
Pden_1594PFAM: Polyphosphate kinase; KEGG: rde:RD1_2042 polyphosphate kinase. (433 aa)
Pden_1835PFAM: protein of unknown function DUF344; KEGG: rsp:RSP_0766 hypothetical protein. (340 aa)
ccoPCytochrome c oxidase, cbb3-type, subunit III; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex. CcoP subunit is required for transferring electrons from donor cytochrome c via its heme groups to CcoO subunit. From there, electrons are shuttled to the catalytic binuclear center of CcoN subunit where oxygen reduction takes place. The complex also functions as a proton pump. (349 aa)
Pden_1846PFAM: Cbb3-type cytochrome oxidase component; KEGG: sit:TM1040_2543 Cbb3-type cytochrome oxidase component. (62 aa)
Pden_1847TIGRFAM: cytochrome c oxidase, cbb3-type, subunit II; PFAM: cytochrome C oxidase, mono-heme subunit/FixO; KEGG: rde:RD1_1271 cytochrome c oxidase, cbb3-type, subunit II. (241 aa)
Pden_1848TIGRFAM: cytochrome c oxidase, cbb3-type, subunit I; PFAM: cytochrome c oxidase, subunit I; KEGG: rsp:RSP_0696 Cbb3-type cytochrome oxidase CcoN subunit; Belongs to the heme-copper respiratory oxidase family. (539 aa)
Pden_1938Cytochrome-c oxidase; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (558 aa)
nuoNNADH dehydrogenase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (499 aa)
Pden_2232KEGG: rsp:RSP_2529 NADH dehydrogenase I chain M (NADH-ubiquinone oxidoreductase chain 13); TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I). (513 aa)
Pden_2233KEGG: rsp:RSP_2527 NADH dehydrogenase I chain L; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH-Ubiquinone oxidoreductase (complex I), chain 5/L domain protein; NADH/Ubiquinone/plastoquinone (complex I). (703 aa)
nuoKNADH dehydrogenase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (101 aa)
Pden_2235NADH dehydrogenase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (199 aa)
nuoINADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (163 aa)
nuoHNADH dehydrogenase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. (345 aa)
Pden_2241NADH dehydrogenase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (674 aa)
Pden_2243NADH dehydrogenase subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (431 aa)
Pden_2246KEGG: rsp:RSP_2516 NADH dehydrogenase-ubiquinone oxidoreductase, chain E; TIGRFAM: NADH-quinone oxidoreductase, E subunit; PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit. (239 aa)
nuoDNADH dehydrogenase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family. (412 aa)
nuoCNADH dehydrogenase subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family. (208 aa)
nuoBNADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (175 aa)
nuoANADH dehydrogenase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (121 aa)
Pden_2305Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (195 aa)
Pden_2306Cytochrome b/b6, N-terminal domain; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (440 aa)
Pden_2307PFAM: cytochrome c1; KEGG: rde:RD1_0565 cytochrome c1. (450 aa)
atpFH+-transporting two-sector ATPase, B/B' subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (184 aa)
atpF-2H+-transporting two-sector ATPase, B/B' subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (215 aa)
atpEATP synthase F0 subcomplex C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (77 aa)
atpBATP synthase F0 subcomplex A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (248 aa)
Pden_3020PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: mca:MCA1549 succinate dehydrogenase, hydrophobic membrane anchor protein, putative. (127 aa)
Pden_3021PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: aeh:Mlg_1332 succinate dehydrogenase, cytochrome b subunit. (125 aa)
Pden_3022KEGG: rru:Rru_A1205 succinate dehydrogenase/fumarate reductase iron-sulfur protein. (122 aa)
Pden_3028PFAM: cytochrome c oxidase, subunit I; KEGG: rsp:RSP_1877 cytochrome c oxidase, aa3 type, subunit I; Belongs to the heme-copper respiratory oxidase family. (556 aa)
Pden_3659Inorganic diphosphatase; PFAM: DHHA2 domain protein; KEGG: rsp:RSP_2307 putative manganese-dependent inorganic pyrophosphatase. (306 aa)
ctaACytochrome oxidase assembly; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily. (391 aa)
Pden_3709PFAM: protein of unknown function DUF344; KEGG: sme:SMa0172 hypothetical protein. (302 aa)
atpHATP synthase F1 subcomplex delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (211 aa)
atpAATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (511 aa)
atpGATP synthase F1 subcomplex gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (290 aa)
atpDATP synthase F1 subcomplex beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (474 aa)
atpCATP synthase F1 subcomplex epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (148 aa)
Pden_4010PFAM: cytochrome bd ubiquinol oxidase, subunit I; KEGG: nar:Saro_1025 cytochrome bd ubiquinol oxidase, subunit I. (467 aa)
Pden_4011TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase, subunit II; KEGG: nar:Saro_1026 cytochrome d ubiquinol oxidase, subunit II. (334 aa)
Pden_4317PFAM: cytochrome c oxidase, subunit III; KEGG: rsp:RSP_1829 cytochrome c oxidase, aa3-type, subunit III. (274 aa)
ctaGCytochrome c oxidase assembly protein CtaG/Cox11; Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I; Belongs to the COX11/CtaG family. (195 aa)
ctaBProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily. (305 aa)
Pden_4321Cytochrome-c oxidase; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). (298 aa)
Pden_4500PFAM: protein of unknown function DUF344; KEGG: rsp:RSP_0013 hypothetical protein. (307 aa)
Your Current Organism:
Paracoccus denitrificans
NCBI taxonomy Id: 318586
Other names: P. denitrificans PD1222, Paracoccus denitrificans PD1222
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.