STRINGSTRING
Pden_0323 Pden_0323 Pden_0541 Pden_0541 Pden_0551 Pden_0551 mdh mdh Pden_0611 Pden_0611 Pden_0848 Pden_0848 Pden_0935 Pden_0935 Pden_1008 Pden_1008 Pden_1254 Pden_1254 Pden_1271 Pden_1271 Pden_1272 Pden_1272 Pden_1364 Pden_1364 Pden_1640 Pden_1640 fumC fumC accD accD Pden_2026 Pden_2026 Pden_2187 Pden_2187 Pden_2224 Pden_2224 Pden_2276 Pden_2276 accA accA adh adh Pden_2663 Pden_2663 Pden_2755 Pden_2755 pckA pckA Pden_2870 Pden_2870 Pden_2907 Pden_2907 Pden_2909 Pden_2909 dld dld Pden_3211 Pden_3211 Pden_3228 Pden_3228 Pden_3260 Pden_3260 gloB gloB Pden_3890 Pden_3890 Pden_3891 Pden_3891 pdhA pdhA Pden_3898 Pden_3898 leuA leuA Pden_4037 Pden_4037 glcB glcB Pden_4062 Pden_4062 Pden_4075 Pden_4075 Pden_4119 Pden_4119 Pden_4144 Pden_4144 ackA ackA Pden_4209 Pden_4209 acsA acsA Pden_4309 Pden_4309
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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Pden_0323PFAM: biotin/lipoyl attachment domain-containing protein; phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: atc:AGR_L_1864 biotin carboxylase protein A2. (588 aa)
Pden_0541Pyruvate phosphate dikinase; PFAM: PEP-utilizing enzyme; PEP-utilising enzyme, mobile region; KEGG: rsp:RSP_1859 pyruvate phosphate dikinase. (853 aa)
Pden_0551TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; FAD dependent oxidoreductase; KEGG: sil:SPO0340 2-oxoglutarate dehydrogenase, E3 component, dihydrolipoamide dehydrogenase. (464 aa)
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa)
Pden_0611TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; KEGG: rsp:RSP_2968 dihydrolipoamide dehydrogenase. (463 aa)
Pden_0848Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: rsp:RSP_1217 phosphate acetyltransferase. (760 aa)
Pden_0935PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: rde:RD1_1872 lactoylglutathione lyase. (142 aa)
Pden_1008KEGG: rsp:RSP_4009 phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase. (318 aa)
Pden_1254PFAM: aldehyde dehydrogenase; KEGG: bxe:Bxe_A3401 betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (481 aa)
Pden_1271acetyl-CoA carboxylase carboxyltransferase subunit alpha; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa)
Pden_1272Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (173 aa)
Pden_1364KEGG: hne:HNE_1238 malate synthase A; TIGRFAM: malate synthase A; PFAM: malate synthase; Belongs to the malate synthase family. (540 aa)
Pden_1640Phosphotransacetylase; KEGG: rsp:RSP_4009 phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase. (318 aa)
fumCFumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa)
accDacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (313 aa)
Pden_2026KEGG: rsp:RSP_0745 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
Pden_2187D-lactate dehydrogenase (cytochrome); PFAM: FAD linked oxidase domain protein; KEGG: rsp:RSP_2120 putative D-lactate dehydrogenase (cytochrome), FAD/FMN-containing oxidoreductase. (459 aa)
Pden_2224Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+))., Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: rsp:RSP_1593 phosphate acetyltransferase. (759 aa)
Pden_2276PFAM: pyruvate kinase; KEGG: sil:SPO3600 pyruvate kinase; Belongs to the pyruvate kinase family. (481 aa)
accAacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (318 aa)
adhAldehyde dehydrogenase (NAD(+)); Catalyzes the NAD(+)-dependent oxidation of acetaldehyde to acetate. (508 aa)
Pden_2663KEGG: sil:SPO0142 beta-ketothiolase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
Pden_2755PFAM: aldehyde dehydrogenase; KEGG: rsp:RSP_1507 aldehyde dehydrogenase. (483 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (532 aa)
Pden_2870KEGG: sil:SPO2918 acetyl-CoA acyltransferase/thiolase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
Pden_2907KEGG: bms:BRA0448 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
Pden_2909PFAM: AMP-dependent synthetase and ligase; KEGG: bms:BRA0450 acetyl-CoA synthetase, putative. (563 aa)
dldD-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. (569 aa)
Pden_3211PFAM: aldehyde dehydrogenase; KEGG: rme:Rmet_1577 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (477 aa)
Pden_3228PFAM: aldehyde dehydrogenase; KEGG: bur:Bcep18194_C7342 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (499 aa)
Pden_3260PFAM: aldehyde dehydrogenase; KEGG: dra:DRA0126 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (470 aa)
gloBHydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (248 aa)
Pden_3890Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (434 aa)
Pden_3891Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (456 aa)
pdhAPyruvate dehydrogenase (acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (343 aa)
Pden_3898PFAM: aldehyde dehydrogenase; KEGG: mes:Meso_0313 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (776 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (520 aa)
Pden_4037PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: jan:Jann_3650 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (306 aa)
glcBMalate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (715 aa)
Pden_4062TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; KEGG: jan:Jann_1959 2-isopropylmalate synthase/homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (540 aa)
Pden_4075L-lactate dehydrogenase (cytochrome); PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: rsp:RSP_0829 lactate dehydrogenase. (387 aa)
Pden_4119Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (501 aa)
Pden_4144Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1144 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (367 aa)
Pden_4209PFAM: phosphate acetyl/butaryl transferase; KEGG: lpp:lpp2215 phosphate acetyltransferase. (308 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa)
Pden_4309PFAM: acetyl-CoA hydrolase/transferase; KEGG: rsp:RSP_0029 acetyl-CoA hydrolase/transferase family protein. (500 aa)
Your Current Organism:
Paracoccus denitrificans
NCBI taxonomy Id: 318586
Other names: P. denitrificans PD1222, Paracoccus denitrificans PD1222
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