STRINGSTRING
Pden_0323 Pden_0323 Pden_0551 Pden_0551 sucD sucD sucC sucC Pden_0611 Pden_0611 Pden_1008 Pden_1008 Pden_1107 Pden_1107 Pden_1271 Pden_1271 Pden_1272 Pden_1272 Pden_1346 Pden_1346 Pden_1347 Pden_1347 Pden_1348 Pden_1348 Pden_1604 Pden_1604 Pden_1640 Pden_1640 Pden_1720 Pden_1720 accD accD Pden_2026 Pden_2026 Pden_2178 Pden_2178 Pden_2225 Pden_2225 Pden_2338 Pden_2338 accA accA Pden_2663 Pden_2663 Pden_2870 Pden_2870 Pden_2871 Pden_2871 Pden_2906 Pden_2906 Pden_2907 Pden_2907 Pden_2909 Pden_2909 Pden_2986 Pden_2986 Pden_3049 Pden_3049 Pden_3681 Pden_3681 Pden_3684 Pden_3684 Pden_3688 Pden_3688 ackA ackA Pden_4209 Pden_4209 acsA acsA Pden_4479 Pden_4479
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Pden_0323PFAM: biotin/lipoyl attachment domain-containing protein; phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: atc:AGR_L_1864 biotin carboxylase protein A2. (588 aa)
Pden_0551TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; FAD dependent oxidoreductase; KEGG: sil:SPO0340 2-oxoglutarate dehydrogenase, E3 component, dihydrolipoamide dehydrogenase. (464 aa)
sucDsuccinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa)
sucCsuccinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (397 aa)
Pden_0611TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; KEGG: rsp:RSP_2968 dihydrolipoamide dehydrogenase. (463 aa)
Pden_1008KEGG: rsp:RSP_4009 phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase. (318 aa)
Pden_1107PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: pol:Bpro_2634 alcohol dehydrogenase, zinc-binding. (331 aa)
Pden_1271acetyl-CoA carboxylase carboxyltransferase subunit alpha; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa)
Pden_1272Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (173 aa)
Pden_13462,3-dimethylmalate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. (304 aa)
Pden_1347KEGG: rme:Rmet_1586 2-methylcitrate synthase/citrate synthase II; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; Belongs to the citrate synthase family. (389 aa)
Pden_13482-methylcitrate dehydratase; PFAM: MmgE/PrpD family protein; KEGG: rpc:RPC_3512 2-methylcitrate dehydratase. (507 aa)
Pden_1604PFAM: dehydrogenase, E1 component; Transketolase, central region; Transketolase domain protein; KEGG: sme:SMb20020 putative pyruvate dehydrogenase E1 component,alpha and beta subunits protein. (693 aa)
Pden_1640Phosphotransacetylase; KEGG: rsp:RSP_4009 phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase. (318 aa)
Pden_1720PFAM: Malonyl-CoA decarboxylase; KEGG: rpb:RPB_0704 malonyl-CoA decarboxylase. (456 aa)
accDacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (313 aa)
Pden_2026KEGG: rsp:RSP_0745 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
Pden_2178methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sit:TM1040_0637 glyoxalase/bleomycin resistance protein/dioxygenase. (134 aa)
Pden_2225PFAM: AMP-dependent synthetase and ligase; KEGG: rsp:RSP_1592 possible acyl-CoA sythetase. (634 aa)
Pden_2338KEGG: sme:SMb21186 putative 4-aminobutyrate aminotransferase protein; TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (422 aa)
accAacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (318 aa)
Pden_2663KEGG: sil:SPO0142 beta-ketothiolase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
Pden_2870KEGG: sil:SPO2918 acetyl-CoA acyltransferase/thiolase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
Pden_2871PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: rsp:RSP_2196 enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxybutyryl-CoA epimerase. (727 aa)
Pden_2906PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: bms:BRA0447 acyl-CoA dehydrogenase. (375 aa)
Pden_2907KEGG: bms:BRA0448 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
Pden_2909PFAM: AMP-dependent synthetase and ligase; KEGG: bms:BRA0450 acetyl-CoA synthetase, putative. (563 aa)
Pden_2986PEP phosphonomutase and related enzymes-like protein; KEGG: rpa:RPA2395 putative carboxyphosphonoenolpyruvate phosphonomutase. (163 aa)
Pden_3049PFAM: dehydrogenase, E1 component; Transketolase, central region; Transketolase domain protein; KEGG: aeh:Mlg_2596 dehydrogenase, E1 component. (617 aa)
Pden_3681KEGG: rsp:RSP_2192 methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. (714 aa)
Pden_3684PFAM: biotin/lipoyl attachment domain-containing protein; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; RimK domain protein ATP-grasp; KEGG: sil:SPO1101 propionyl-CoA carboxylase, alpha subunit. (685 aa)
Pden_3688PFAM: carboxyl transferase; KEGG: rsp:RSP_2189 propionyl-CoA carboxylase beta chain. (510 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (367 aa)
Pden_4209PFAM: phosphate acetyl/butaryl transferase; KEGG: lpp:lpp2215 phosphate acetyltransferase. (308 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa)
Pden_4479TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: sit:TM1040_1106 methylmalonate-semialdehyde dehydrogenase. (499 aa)
Your Current Organism:
Paracoccus denitrificans
NCBI taxonomy Id: 318586
Other names: P. denitrificans PD1222, Paracoccus denitrificans PD1222
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