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| | gfa | Glutathione-dependent formaldehyde-activating, GFA; Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione; Belongs to the Gfa family. (194 aa) |
| | Pden_0016 | PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: rsp:RSP_2576 alcohol dehydrogenase class III; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (375 aa) |
| | fghA | Carboxylesterase; Serine hydrolase involved in the detoxification of formaldehyde. Hydrolyzes S-formylglutathione to glutathione and formate (Probable). (279 aa) |
| | Pden_0194 | KEGG: bxe:Bxe_C0656 hypothetical protein. (274 aa) |
| | Pden_0197 | KEGG: pen:PSEEN2793 3-hydroxyacyl-CoA dehydrogenase PhaC; TIGRFAM: 3-hydroxyacyl-CoA dehydrogenase PaaC; PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding. (509 aa) |
| | Pden_0201 | PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: jan:Jann_0676 3-hydroxyacyl-CoA dehydrogenase, NAD-binding. (690 aa) |
| | Pden_0221 | KEGG: bxe:Bxe_C0656 hypothetical protein. (287 aa) |
| | Pden_0285 | PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: ret:RHE_PF00182 probable threonine dehydratase protein. (318 aa) |
| | Pden_0323 | PFAM: biotin/lipoyl attachment domain-containing protein; phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: atc:AGR_L_1864 biotin carboxylase protein A2. (588 aa) |
| | ilvA | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (412 aa) |
| | Pden_0541 | Pyruvate phosphate dikinase; PFAM: PEP-utilizing enzyme; PEP-utilising enzyme, mobile region; KEGG: rsp:RSP_1859 pyruvate phosphate dikinase. (853 aa) |
| | Pden_0551 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; FAD dependent oxidoreductase; KEGG: sil:SPO0340 2-oxoglutarate dehydrogenase, E3 component, dihydrolipoamide dehydrogenase. (464 aa) |
| | Pden_0554 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (510 aa) |
| | Pden_0555 | KEGG: rsp:RSP_0965 2-oxoglutarate dehydrogenase E1 component (alpha-ketoglutarate dehydrogenase); TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase, E1 component; Transketolase, central region. (988 aa) |
| | sucD | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa) |
| | sucC | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (397 aa) |
| | mdh | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa) |
| | Pden_0563 | Citryl-CoA lyase; PFAM: HpcH/HpaI aldolase; KEGG: rsp:RSP_0970 putative citrate lyase beta chain; Belongs to the HpcH/HpaI aldolase family. (279 aa) |
| | Pden_0566 | PFAM: MaoC domain protein dehydratase; KEGG: sil:SPO0355 hypothetical protein. (344 aa) |
| | Pden_0567 | PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: rsp:RSP_0974 succinate dehydrogenase cytochrome b-556 subunit. (130 aa) |
| | Pden_0568 | KEGG: rsp:RSP_0975 putative succinate dehydrogenase, hydrophobic membrane anchor protein. (129 aa) |
| | Pden_0569 | KEGG: rsp:RSP_0976 succinate dehydrogenase; TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (600 aa) |
| | Pden_0572 | TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: rde:RD1_1630 succinate dehydrogenase, iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (259 aa) |
| | Pden_0611 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; KEGG: rsp:RSP_2968 dihydrolipoamide dehydrogenase. (463 aa) |
| | Pden_0729 | PFAM: aminotransferase, class V; KEGG: rsp:RSP_0245 serine-pyruvate aminotransferase/aspartate aminotransferase. (390 aa) |
| | Pden_0799 | Citrate (pro-3S)-lyase; PFAM: HpcH/HpaI aldolase; KEGG: rde:RD1_1001 citrate lyase, beta subunit, putative; Belongs to the HpcH/HpaI aldolase family. (341 aa) |
| | Pden_0812 | KEGG: sil:SPO3353 phosphoserine phosphatase; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. (291 aa) |
| | Pden_0813 | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (384 aa) |
| | Pden_0814 | TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: amino acid-binding ACT domain protein; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: rsp:RSP_1352 D-3-phosphoglycerate dehydrogenase. (529 aa) |
| | Pden_0848 | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: rsp:RSP_1217 phosphate acetyltransferase. (760 aa) |
| | Pden_0882 | 6-phosphofructokinase; PFAM: PfkB domain protein; KEGG: rsp:RSP_2334 carbohydrate kinase, PfkB; Belongs to the carbohydrate kinase PfkB family. (319 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (427 aa) |
| | Pden_1008 | KEGG: rsp:RSP_4009 phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase. (318 aa) |
| | Pden_1060 | KEGG: sil:SPO0875 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (331 aa) |
| | Pden_1161 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (401 aa) |
| | Pden_1186 | Glutathione-independent formaldehyde dehydrogenase; PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: atc:AGR_C_2885 hypothetical protein. (394 aa) |
| | Pden_1245 | KEGG: sil:SPO3031 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase. (212 aa) |
| | Pden_1271 | acetyl-CoA carboxylase carboxyltransferase subunit alpha; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa) |
| | Pden_1272 | Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (173 aa) |
| | Pden_1275 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (672 aa) |
| | Pden_1293 | KEGG: mca:MCA1436 serine acetyltransferase CysE, putative. (180 aa) |
| | fhs1 | PFAM: formate-tetrahydrofolate ligase, FTHFS; KEGG: rsp:RSP_0663 formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (555 aa) |
| | Pden_1363 | PFAM: isocitrate lyase and phosphorylmutase; KEGG: ccr:CC1764 isocitrate lyase. (535 aa) |
| | Pden_1364 | KEGG: hne:HNE_1238 malate synthase A; TIGRFAM: malate synthase A; PFAM: malate synthase; Belongs to the malate synthase family. (540 aa) |
| | Pden_1603 | Dihydrolipoyllysine-residue succinyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: sme:SMb20019 putative dihydrolipoamide succinyltransferase protein. (377 aa) |
| | Pden_1640 | Phosphotransacetylase; KEGG: rsp:RSP_4009 phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase. (318 aa) |
| | fbp | PFAM: Inositol phosphatase/fructose-1,6-bisphosphatase; KEGG: rsp:RSP_1285 fructose-1,6-bisphosphatase I. (330 aa) |
| | Pden_1696 | PFAM: phosphoribulokinase/uridine kinase; KEGG: rsp:RSP_1284 phosphoribulokinase. (290 aa) |
| | Pden_1697 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (668 aa) |
| | Pden_1698 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (359 aa) |
| | cbbL | Ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site; Belongs to the RuBisCO large chain family. Type I subfamily. (487 aa) |
| | Pden_1700 | PFAM: ribulose bisphosphate carboxylase, small chain; KEGG: rpa:RPA1560 ribulose-bisphosphate carboxylase small chain. (129 aa) |
| | Pden_1876 | TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; KEGG: rsp:RSP_0404 fructose - 1,6 - bisphosphatase, GlpX-like. (321 aa) |
| | fumC | Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa) |
| | pgk | PFAM: phosphoglycerate kinase; KEGG: rsp:RSP_4044 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (398 aa) |
| | Pden_1920 | PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: rsp:RSP_4045 fructose-bisphosphate aldolase. (309 aa) |
| | pgi | PFAM: phosphoglucose isomerase (PGI); KEGG: rsp:RSP_2736 glucose-6-phosphate isomerase; Belongs to the GPI family. (533 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (224 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (500 aa) |
| | edd | 6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (600 aa) |
| | accD | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (313 aa) |
| | Pden_2026 | KEGG: rsp:RSP_0745 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa) |
| | Pden_2027 | TIGRFAM: acetoacetyl-CoA reductase; PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: rsp:RSP_0747 short-chain dehydrogenase/reductase. (241 aa) |
| | Pden_2178 | methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sit:TM1040_0637 glyoxalase/bleomycin resistance protein/dioxygenase. (134 aa) |
| | Pden_2195 | Hydroxypyruvate reductase; PFAM: MOFRL domain protein; KEGG: sit:TM1040_3471 hydroxypyruvate reductase. (408 aa) |
| | Pden_2224 | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+))., Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: rsp:RSP_1593 phosphate acetyltransferase. (759 aa) |
| | Pden_2276 | PFAM: pyruvate kinase; KEGG: sil:SPO3600 pyruvate kinase; Belongs to the pyruvate kinase family. (481 aa) |
| | Pden_2319 | TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; KEGG: rsp:RSP_2172 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (287 aa) |
| | accA | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (318 aa) |
| | gcvP | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (942 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (118 aa) |
| | Pden_2348 | TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel; KEGG: rsp:RSP_2193 predicted aminomethyltransferase, tetrahydrofolate dependent. (370 aa) |
| | Pden_2393 | 6-phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (466 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (217 aa) |
| | gpmI | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (507 aa) |
| | Pden_2552 | PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 6-phosphogluconate dehydrogenase, NAD-binding; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: rsp:RSP_1687 3-hydroxybutyryl-CoA dehydrogenase. (291 aa) |
| | Pden_2572 | PFAM: ribulose-phosphate 3-epimerase; KEGG: rsp:RSP_2864 pentose-5-phosphate-3-epimerase. (244 aa) |
| | folD1 | 5,10-methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (298 aa) |
| | Pden_2663 | KEGG: sil:SPO0142 beta-ketothiolase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa) |
| | Pden_2680 | PFAM: Glucokinase; KEGG: sil:SPO0864 glucokinase, putative; Belongs to the bacterial glucokinase family. (307 aa) |
| | Pden_2827 | TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: sme:SMa0007 probable FdoI formate dehydrogenase-O,gamma subunit. (228 aa) |
| | Pden_2828 | TIGRFAM: formate dehydrogenase, beta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: sme:SMa0005 probable FdoH formate dehydrogenase-O, beta subunit. (332 aa) |
| | Pden_2829 | KEGG: sme:SMa0002 probable FdoG formate dehydrogenase-O alpha subunit; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (820 aa) |
| | Pden_2830 | PFAM: molybdopterin oxidoreductase Fe4S4 region; KEGG: sme:SMa0002 probable FdoG formate dehydrogenase-O alpha subunit. (199 aa) |
| | Pden_2840 | PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: rsp:RSP_1679 acyl-CoA dehydrogenase. (551 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (532 aa) |
| | Pden_2854 | KEGG: sme:SMc03086 putative NAD-dependent formate dehydrogenase delta subunit protein. (73 aa) |
| | Pden_2856 | TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: rsp:RSP_1080 NAD-dependent formate dehydrogenase, alpha subunit. (959 aa) |
| | Pden_2857 | PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: rsp:RSP_1079 NAD dependent formate dehydrogenase, beta subunit (51 kDa). (513 aa) |
| | Pden_2858 | PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit; KEGG: gbe:GbCGDNIH1_1932 NAD-dependent formate dehydrogenase gamma subunit (FdsG). (159 aa) |
| | Pden_2870 | KEGG: sil:SPO2918 acetyl-CoA acyltransferase/thiolase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa) |
| | Pden_2871 | PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: rsp:RSP_2196 enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxybutyryl-CoA epimerase. (727 aa) |
| | Pden_2885 | KEGG: rsp:RSP_2481 serine acetyltransferase; TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; serine acetyltransferase domain protein. (279 aa) |
| | Pden_2906 | PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: bms:BRA0447 acyl-CoA dehydrogenase. (375 aa) |
| | Pden_2907 | KEGG: bms:BRA0448 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa) |
| | Pden_2909 | PFAM: AMP-dependent synthetase and ligase; KEGG: bms:BRA0450 acetyl-CoA synthetase, putative. (563 aa) |
| | Pden_2932 | Gluconate kinase, SKI family; KEGG: tfu:Tfu_2114 carbohydrate kinase, thermoresistant glucokinase; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: shikimate kinase. (167 aa) |
| | Pden_2961 | KEGG: rsp:RSP_1559 isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (404 aa) |
| | Pden_2993 | PFAM: Pyrrolo-quinoline quinone; KEGG: rpe:RPE_3139 pyrrolo-quinoline quinone. (632 aa) |
| | Pden_2996 | Methanol dehydrogenase, beta subunit; Catalyzes the oxidation of primary alcohols including methanol. (103 aa) |
| | Pden_3020 | PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: mca:MCA1549 succinate dehydrogenase, hydrophobic membrane anchor protein, putative. (127 aa) |
| | Pden_3021 | PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: aeh:Mlg_1332 succinate dehydrogenase, cytochrome b subunit. (125 aa) |
| | Pden_3022 | KEGG: rru:Rru_A1205 succinate dehydrogenase/fumarate reductase iron-sulfur protein. (122 aa) |
| | Pden_3071 | Aconitase; PFAM: aconitate hydratase domain protein; KEGG: pol:Bpro_3871 aconitate hydratase-like. (854 aa) |
| | Pden_3225 | PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: rru:Rru_A1309 acetoacetyl-CoA reductase. (765 aa) |
| | Pden_3433 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: rsp:RSP_3447 putative dehydrogenase. (316 aa) |
| | Pden_3569 | Formamidase; PFAM: Acetamidase/Formamidase; KEGG: bbr:BB1405 formamidase. (408 aa) |
| | Pden_3661 | PFAM: MaoC domain protein dehydratase; KEGG: rsp:RSP_2305 MaoC family protein. (148 aa) |
| | rpiA | Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (241 aa) |
| | Pden_3681 | KEGG: rsp:RSP_2192 methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. (714 aa) |
| | Pden_3684 | PFAM: biotin/lipoyl attachment domain-containing protein; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; RimK domain protein ATP-grasp; KEGG: sil:SPO1101 propionyl-CoA carboxylase, alpha subunit. (685 aa) |
| | Pden_3688 | PFAM: carboxyl transferase; KEGG: rsp:RSP_2189 propionyl-CoA carboxylase beta chain. (510 aa) |
| | Pden_3716 | KEGG: sit:TM1040_1132 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. (430 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (339 aa) |
| | Pden_3861 | PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: rsp:RSP_2147 O-acetylserine (thiol)-lyase, cysteine synthase. (343 aa) |
| | Pden_3873 | TIGRFAM: crotonyl-CoA reductase; PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: rsp:RSP_0960 alcohol dehydrogenase. (429 aa) |
| | Pden_3875 | KEGG: sil:SPO0368 methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. (688 aa) |
| | Pden_3890 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (434 aa) |
| | Pden_3891 | Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (456 aa) |
| | pdhA | Pyruvate dehydrogenase (acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (343 aa) |
| | bhcB | Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; Catalyzes the dehydration of (2R,3S)-beta-hydroxyaspartate ((3S)-3-hydroxy-D-aspartate) into iminosuccinate. Is essential for the growth of P.denitrificans in the presence of glycolate and glyoxylate since it functions in glyoxylate assimilation via the beta- hydroxyaspartate cycle (BHAC). (315 aa) |
| | bhcA | Serine-glyoxylate aminotransferase apoenzyme; Catalyzes the transamination of glyoxylate into glycine using L-aspartate as the preferred amino group donor. Is essential for the growth of P.denitrificans in the presence of glycolate and glyoxylate since it functions in glyoxylate assimilation via the beta- hydroxyaspartate cycle (BHAC). Can catalyze the reverse reaction in vitro, and also use L-serine and L-glutamate as amino group donor, but with much less efficiency than L-aspartate. (396 aa) |
| | glcB | Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (715 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (425 aa) |
| | Pden_4111 | KEGG: bmb:BruAb2_0162 hypothetical protein. (277 aa) |
| | Pden_4119 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (501 aa) |
| | Pden_4132 | KEGG: rsp:RSP_0361 probable L-serine dehydratase protein; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. (460 aa) |
| | Pden_4144 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1144 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (367 aa) |
| | Pden_4209 | PFAM: phosphate acetyl/butaryl transferase; KEGG: lpp:lpp2215 phosphate acetyltransferase. (308 aa) |
| | acsA | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa) |
| | Pden_4301 | Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (919 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (247 aa) |
| | Pden_4309 | PFAM: acetyl-CoA hydrolase/transferase; KEGG: rsp:RSP_0029 acetyl-CoA hydrolase/transferase family protein. (500 aa) |
| | Pden_4465 | KEGG: rsp:RSP_2959 glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa) |
| | Pden_4479 | TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: sit:TM1040_1106 methylmalonate-semialdehyde dehydrogenase. (499 aa) |
| | Pden_4513 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: rsp:RSP_1340 enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa) |
