STRINGSTRING
rho rho ppk ppk Pden_1594 Pden_1594 Pden_1743 Pden_1743 Pden_1835 Pden_1835 Pden_2228 Pden_2228 dnaK dnaK rppH rppH Pden_2575 Pden_2575 Pden_2656 Pden_2656 pnp pnp rnr rnr rne rne groL1 groL1 Pden_3709 Pden_3709 eno eno hfq hfq Pden_4366 Pden_4366 Pden_4500 Pden_4500
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (434 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (721 aa)
Pden_1594PFAM: Polyphosphate kinase; KEGG: rde:RD1_2042 polyphosphate kinase. (433 aa)
Pden_1743PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: rsp:RSP_0819 DEAD/DEAH box helicase. (479 aa)
Pden_1835PFAM: protein of unknown function DUF344; KEGG: rsp:RSP_0766 hypothetical protein. (340 aa)
Pden_2228PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: rsp:RSP_2534 predicted hydrolase of the metallo-beta-lactamase superfamily. (558 aa)
dnaKChaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (638 aa)
rppHNUDIX hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. (163 aa)
Pden_2575PFAM: Polynucleotide adenylyltransferase region; KEGG: rsp:RSP_1205 poly A polymerase family protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (388 aa)
Pden_2656ATP-dependent DNA helicase RecQ; KEGG: rsp:RSP_1359 DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. (790 aa)
pnp3' exoribonuclease; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (736 aa)
rnrRNAse R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (754 aa)
rneRNAse E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (869 aa)
groL1Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (545 aa)
Pden_3709PFAM: protein of unknown function DUF344; KEGG: sme:SMa0172 hypothetical protein. (302 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (425 aa)
hfqRNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. (77 aa)
Pden_4366PFAM: helicase domain protein; DbpA, RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: rsp:RSP_1485 ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (687 aa)
Pden_4500PFAM: protein of unknown function DUF344; KEGG: rsp:RSP_0013 hypothetical protein. (307 aa)
Your Current Organism:
Paracoccus denitrificans
NCBI taxonomy Id: 318586
Other names: P. denitrificans PD1222, Paracoccus denitrificans PD1222
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