STRINGSTRING
dtd dtd tdh tdh ABP77355.1 ABP77355.1 ABP77354.1 ABP77354.1 prpB prpB ABP77263.1 ABP77263.1 ABP77023.1 ABP77023.1 gcvT gcvT gcvH gcvH gcvP gcvP ABP76834.1 ABP76834.1 ABP76812.1 ABP76812.1 slyX slyX ABP76235.1 ABP76235.1 ABP76234.1 ABP76234.1 fadI fadI fadJ fadJ ABP76152.1 ABP76152.1 ABP75989.1 ABP75989.1 astB astB ABP75963.1 ABP75963.1 ABP75916.1 ABP75916.1 ABP75798.1 ABP75798.1 ABP75734.1 ABP75734.1 ABP75609.1 ABP75609.1 ABP75608.1 ABP75608.1 astE astE edd edd ABP75586.1 ABP75586.1 ABP75516.1 ABP75516.1 ABP75440.1 ABP75440.1 ABP75396.1 ABP75396.1 ABP75379.1 ABP75379.1 speA speA ABP75129.1 ABP75129.1 ABP75128.1 ABP75128.1 ABP75124.1 ABP75124.1 ABP75116.1 ABP75116.1 ABP75113.1 ABP75113.1 ABP75042.1 ABP75042.1 ABP75040.1 ABP75040.1 ABP74999.1 ABP74999.1 ABP74937.1 ABP74937.1 anmK anmK astD astD ABP74376.1 ABP74376.1 ABP74193.1 ABP74193.1 ABP74172.1 ABP74172.1 hutH hutH hutU hutU hutI hutI ABP73802.1 ABP73802.1 ABP73799.1 ABP73799.1 fadB fadB fadA fadA ABP73745.1 ABP73745.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (145 aa)
tdhL-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (341 aa)
ABP77355.1Methylitaconate delta2-delta3-isomerase; TIGRFAM: putative AcnD-accessory protein PrpF; PFAM: protein of unknown function DUF453; KEGG: shm:Shewmr7_0312 putative AcnD-accessory protein PrpF. (397 aa)
ABP77354.1Aconitase; TIGRFAM: 2-methylisocitrate dehydratase, Fe/S-dependent; PFAM: aconitate hydratase domain protein; KEGG: son:SO0343 aconitate hydratase 1. (871 aa)
prpB2,3-dimethylmalate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (292 aa)
ABP77263.1PFAM: Phytanoyl-CoA dioxygenase; KEGG: son:SO0180 hypothetical protein. (360 aa)
ABP77023.1KEGG: shm:Shewmr7_3464 hypothetical protein. (394 aa)
gcvTGlycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (364 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (962 aa)
ABP76834.1PFAM: alpha/beta hydrolase fold; KEGG: son:SO0880 hypothetical protein. (342 aa)
ABP76812.1Delta-1-pyrroline-5-carboxylate dehydrogenase / L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1064 aa)
slyXPFAM: SlyX family protein; KEGG: she:Shewmr4_3036 SlyX family protein; Belongs to the SlyX family. (70 aa)
ABP76235.1KEGG: son:SO3149 hypothetical protein. (438 aa)
ABP76234.1PFAM: amidohydrolase; KEGG: shm:Shewmr7_1415 amidohydrolase. (1029 aa)
fadI3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (436 aa)
fadJ3-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (706 aa)
ABP76152.1PFAM: phenylalanine/histidine ammonia-lyase; KEGG: son:SO3057 Pal/histidase family protein. (545 aa)
ABP75989.12-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (400 aa)
astBSuccinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2). (444 aa)
ABP75963.1PFAM: FAD linked oxidase domain protein; KEGG: she:Shewmr4_1593 FAD linked oxidase domain protein. (1013 aa)
ABP75916.1PFAM: NAD-glutamate dehydrogenase; KEGG: shm:Shewmr7_1755 NAD-glutamate dehydrogenase. (1614 aa)
ABP75798.1PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: she:Shewmr4_1910 NADH:flavin oxidoreductase/NADH oxidase. (672 aa)
ABP75734.1TIGRFAM: alanine dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Shikimate/quinate 5-dehydrogenase; alanine dehydrogenase/PNT domain protein; KEGG: shm:Shewmr7_2015 alanine dehydrogenase; Belongs to the AlaDH/PNT family. (371 aa)
ABP75609.1PFAM: Transketolase, central region; Transketolase domain protein; KEGG: shm:Shewmr7_1948 transketolase, central region. (325 aa)
ABP75608.1PFAM: dehydrogenase, E1 component; KEGG: shm:Shewmr7_1947 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring). (392 aa)
astESuccinylglutamate desuccinylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily. (344 aa)
edd6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (613 aa)
ABP75586.1PFAM: acyl-CoA dehydrogenase domain protein; KEGG: son:SO2492 oxidoreductase, acyl-CoA dehydrogenase family. (759 aa)
ABP75516.1PFAM: acyl-CoA dehydrogenase domain protein; KEGG: shm:Shewmr7_2223 acyl-CoA dehydrogenase domain protein. (815 aa)
ABP75440.1hydroxymethylglutaryl-CoA lyase; PFAM: pyruvate carboxyltransferase; KEGG: shm:Shewmr7_2398 pyruvate carboxyltransferase. (315 aa)
ABP75396.1PFAM: homogentisate 1,2-dioxygenase; KEGG: shm:Shewmr7_2363 homogentisate 1,2-dioxygenase. (386 aa)
ABP75379.1PFAM: histidine triad (HIT) protein; KEGG: shm:Shewmr7_2384 histidine triad (HIT) protein. (118 aa)
speAArginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. (637 aa)
ABP75129.1KEGG: shm:Shewmr7_2659 3-hydroxyisobutyrate dehydrogenase; TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; Belongs to the HIBADH-related family. (300 aa)
ABP75128.1PFAM: Enoyl-CoA hydratase/isomerase; KEGG: shm:Shewmr7_2660 enoyl-CoA hydratase/isomerase. (389 aa)
ABP75124.1KEGG: shm:Shewmr7_2664 acetyl-CoA acetyltransferases; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
ABP75116.1PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: son:SO1670 fumarylacetoacetate hydrolase family protein. (328 aa)
ABP75113.1KEGG: shm:Shewmr7_2674 phenylalanine-4-hydroxylase; TIGRFAM: phenylalanine-4-hydroxylase; PFAM: aromatic amino acid hydroxylase. (266 aa)
ABP75042.1PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: son:SO1585 fumarylacetoacetate hydrolase family protein. (208 aa)
ABP75040.1PFAM: Succinylglutamate desuccinylase/aspartoacylase; KEGG: son:SO1583 hypothetical protein. (337 aa)
ABP74999.1PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; FAD linked oxidase domain protein; KEGG: son:SO1521 iron-sulfur cluster-binding protein. (934 aa)
ABP74937.1PFAM: protein of unknown function DUF1063; KEGG: shm:Shewmr7_2876 protein of unknown function DUF1063; Belongs to the UPF0597 family. (424 aa)
anmKProtein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (369 aa)
astDSuccinylglutamic semialdehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate. (486 aa)
ABP74376.1PFAM: arginine N-succinyltransferase beta subunit; KEGG: shm:Shewmr7_3418 arginine N-succinyltransferase. (339 aa)
ABP74193.1Phosphopantothenoylcysteine decarboxylase / Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (406 aa)
ABP74172.1PFAM: phenylalanine/histidine ammonia-lyase; KEGG: she:Shewmr4_0344 histidine ammonia-lyase. (524 aa)
hutHKEGG: shm:Shewmr7_0095 histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase. (513 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (555 aa)
hutIImidazolonepropionase; KEGG: shm:Shewmr7_0092 imidazolonepropionase; TIGRFAM: imidazolonepropionase; PFAM: amidohydrolase; Amidohydrolase 3; Belongs to the metallo-dependent hydrolases superfamily. HutI family. (408 aa)
ABP73802.1PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_0081 thioesterase superfamily protein. (146 aa)
ABP73799.1PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_0078 thioesterase superfamily protein. (136 aa)
fadB3-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (716 aa)
fadA3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (387 aa)
ABP73745.1Amidohydrolase; PFAM: peptidase S9B, dipeptidylpeptidase IV domain protein; amidohydrolase; WD40 domain protein beta Propeller; KEGG: she:Shewmr4_0011 amidohydrolase. (1062 aa)
Your Current Organism:
Shewanella putrefaciens
NCBI taxonomy Id: 319224
Other names: S. putrefaciens CN-32, Shewanella putrefaciens CN-32, Shewanella putrefaciens str. CN-32, Shewanella putrefaciens strain CN-32
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