STRINGSTRING
accA accA ARN70988.1 ARN70988.1 BST91_04795 BST91_04795 gshB gshB ARN71059.1 ARN71059.1 purA purA sucD sucD ARN71233.1 ARN71233.1 ARN71399.1 ARN71399.1 ligA ligA ARN71415.1 ARN71415.1 ARN71419.1 ARN71419.1 ARN71489.1 ARN71489.1 purL purL pheT pheT lysS lysS ARN71630.1 ARN71630.1 ARN71638.1 ARN71638.1 ARN71646.1 ARN71646.1 ARN71734.1 ARN71734.1 proS proS cysS cysS murF murF ARN71903.1 ARN71903.1 ARN71977.1 ARN71977.1 ARN71979.1 ARN71979.1 pheS pheS ARN72076.1 ARN72076.1 ARN72092.1 ARN72092.1 ARN72094.1 ARN72094.1 leuS leuS ARN72120.1 ARN72120.1 ARN72121.1 ARN72121.1 ARN72172.1 ARN72172.1 ARN72174.1 ARN72174.1 gltX gltX ARN72200.1 ARN72200.1 ARN72227.1 ARN72227.1 atpE atpE atpF atpF atpH atpH atpA atpA atpG atpG ARN72261.1 ARN72261.1 bioD bioD ARN72294.1 ARN72294.1 ARN72305.1 ARN72305.1 atpD atpD panC panC ARN72335.1 ARN72335.1 ARN72336.1 ARN72336.1 ARN72358.1 ARN72358.1 aspS aspS ARN72628.1 ARN72628.1 ARN72388.1 ARN72388.1 ARN72389.1 ARN72389.1 ileS ileS metG metG ARN72439.1 ARN72439.1 tyrS tyrS ARN72466.1 ARN72466.1 asnS asnS ARN70178.1 ARN70178.1 purK purK accD accD ARN70301.1 ARN70301.1 ARN70320.1 ARN70320.1 murE murE murD murD murC murC ARN70337.1 ARN70337.1 ARN70417.1 ARN70417.1 asnB asnB ARN70446.1 ARN70446.1 ARN70452.1 ARN70452.1 ddl ddl carA carA ARN70528.1 ARN70528.1 ARN70529.1 ARN70529.1 ARN70565.1 ARN70565.1 argS argS bshC bshC ARN70609.1 ARN70609.1 pyrG pyrG ARN70622.1 ARN70622.1 ARN70659.1 ARN70659.1 tilS tilS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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accAacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa)
ARN70988.1Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
BST91_04795Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (592 aa)
gshBGlutathione synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic GSH synthase family. (343 aa)
ARN71059.1histidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (456 aa)
purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (423 aa)
sucDsuccinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (291 aa)
ARN71233.1succinate--CoA ligase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
ARN71399.1Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (402 aa)
ligADNA ligase (NAD(+)) LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (684 aa)
ARN71415.1alanine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (873 aa)
ARN71419.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)
ARN71489.1Magnesium chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (487 aa)
purLPhosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1224 aa)
pheTphenylalanine--tRNA ligase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (808 aa)
lysSlysine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (563 aa)
ARN71630.1methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (542 aa)
ARN71638.1threonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (648 aa)
ARN71646.1Amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (532 aa)
ARN71734.1tRNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (111 aa)
proSproline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (492 aa)
cysScysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (494 aa)
murFUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (421 aa)
ARN71903.1Peptidoglycan synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (451 aa)
ARN71977.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (506 aa)
ARN71979.1DNA/RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1799 aa)
pheSphenylalanine--tRNA ligase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (339 aa)
ARN72076.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (498 aa)
ARN72092.1tryptophan--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (322 aa)
ARN72094.1glycine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (515 aa)
leuSleucine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (951 aa)
ARN72120.1Aerotolerance regulator BatA; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
ARN72121.1BatB protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
ARN72172.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (439 aa)
ARN72174.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
gltXglutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (505 aa)
ARN72200.1glutamine--tRNA ligase; Catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (558 aa)
ARN72227.1ATP synthase F0 subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (401 aa)
atpEATP synthase F0 subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (62 aa)
atpFATP synthase F0 subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (165 aa)
atpHATP synthase F1 subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (177 aa)
atpAATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (524 aa)
atpGATP synthase F1 subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (291 aa)
ARN72261.1AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
bioDDethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (205 aa)
ARN72294.1Phosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa)
ARN72305.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (91 aa)
atpDF0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (503 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (284 aa)
ARN72335.1acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (163 aa)
ARN72336.1acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (446 aa)
ARN72358.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
aspSaspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (583 aa)
ARN72628.1Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)
ARN72388.1alpha-L-glutamate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
ARN72389.15-formyltetrahydrofolate cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (191 aa)
ileSisoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1134 aa)
metGmethionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (683 aa)
ARN72439.1ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (542 aa)
tyrStyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (443 aa)
ARN72466.1Acyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
asnSasparagine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (478 aa)
ARN70178.1serine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (423 aa)
purK5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (381 aa)
accDFeS-binding protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (285 aa)
ARN70301.1Tetrahydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
ARN70320.1NAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (263 aa)
murEUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (488 aa)
murDUDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (452 aa)
murCUDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (450 aa)
ARN70337.1glutamyl-tRNA amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa)
ARN70417.1acetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (636 aa)
asnBFunctions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; Derived by automated computational analysis using gene prediction method: Protein Homology. (553 aa)
ARN70446.1valine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (876 aa)
ARN70452.1biotin--[acetyl-CoA-carboxylase] ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
ddlD-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (323 aa)
carACarbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (372 aa)
ARN70528.1Phosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
ARN70529.1Glutamine synthetase type III; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (728 aa)
ARN70565.1O-succinylbenzoic acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
argSarginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (594 aa)
bshCBacillithiol biosynthesis cysteine-adding enzyme BshC; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BshC family. (535 aa)
ARN70609.1Glutamine-hydrolyzing GMP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (511 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (539 aa)
ARN70622.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (108 aa)
ARN70659.1Carbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family. (950 aa)
tilSAminodeoxychorismate synthase component I; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (444 aa)
Your Current Organism:
Nonlabens sediminis
NCBI taxonomy Id: 319236
Other names: Flavobacteriaceae bacterium JCM 19294, LMG 23247, LMG:23247, N. sediminis, NBRC 100970, Nonlabens sediminis (Khan et al. 2006) Yi and Chun 2012, Sandarakinotalea sediminis, Sandarakinotalea sediminis Khan et al. 2006, strain CKA-5
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