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ANN14324.1 ANN14324.1 ANN14511.1 ANN14511.1 ANN14565.1 ANN14565.1 ANN14618.1 ANN14618.1 ANN14654.1 ANN14654.1 ANN15253.1 ANN15253.1 ANN15422.1 ANN15422.1 ANN15428.1 ANN15428.1 ANN15429.1 ANN15429.1 ANN15434.1 ANN15434.1 ANN15440.1 ANN15440.1 ANN15441.1 ANN15441.1 ANN15442.1 ANN15442.1 ANN15445.1 ANN15445.1 ANN15567.1 ANN15567.1 ANN15677.1 ANN15677.1 ANN15704.1 ANN15704.1 ANN21637.1 ANN21637.1 ANN15795.1 ANN15795.1 ANN15796.1 ANN15796.1 ANN15847.1 ANN15847.1 ANN15848.1 ANN15848.1 ANN15915.1 ANN15915.1 ANN16057.1 ANN16057.1 maiA maiA ANN16121.1 ANN16121.1 ANN16295.1 ANN16295.1 ANN16429.1 ANN16429.1 ANN16430.1 ANN16430.1 gabD2 gabD2 ANN16530.1 ANN16530.1 ANN16579.1 ANN16579.1 ANN16584.1 ANN16584.1 ANN16601.1 ANN16601.1 ANN16602.1 ANN16602.1 ANN21745.1 ANN21745.1 ANN16610.1 ANN16610.1 ANN21746.1 ANN21746.1 ANN16682.1 ANN16682.1 ANN17175.1 ANN17175.1 gabD2-2 gabD2-2 ANN17344.1 ANN17344.1 ANN17424.1 ANN17424.1 ANN17514.1 ANN17514.1 ANN17541.1 ANN17541.1 ANN18247.1 ANN18247.1 ANN18616.1 ANN18616.1 ANN18755.1 ANN18755.1 ANN19327.1 ANN19327.1 ANN19350.1 ANN19350.1 ANN19351.1 ANN19351.1 ANN19849.1 ANN19849.1 ANN20330.1 ANN20330.1 ANN20541.1 ANN20541.1 ANN20633.1 ANN20633.1 ANN20634.1 ANN20634.1 ANN20635.1 ANN20635.1 ANN20636.1 ANN20636.1 ANN20896.1 ANN20896.1 ANN20897.1 ANN20897.1 ANN20898.1 ANN20898.1 ANN21056.1 ANN21056.1 ANN21220.1 ANN21220.1 ANN21304.1 ANN21304.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANN14324.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (429 aa)
ANN14511.13-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
ANN14565.13-hydroxyacyl-CoA dehydrogenase; Converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation; Derived by automated computational analysis using gene prediction method: Protein Homology. (506 aa)
ANN14618.1Glutamate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
ANN14654.13-hydroxybutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
ANN15253.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
ANN15422.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)
ANN15428.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
ANN15429.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (723 aa)
ANN15434.1Decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (517 aa)
ANN15440.14-aminobutyrate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (416 aa)
ANN15441.1NAD-dependent succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (487 aa)
ANN15442.1Tartrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
ANN15445.1Asp/Glu/hydantoin racemase; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
ANN15567.13-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (591 aa)
ANN15677.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
ANN15704.1crotonyl-CoA carboxylase/reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (446 aa)
ANN21637.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
ANN15795.1Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (624 aa)
ANN15796.1Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (168 aa)
ANN15847.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (706 aa)
ANN15848.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (409 aa)
ANN15915.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (335 aa)
ANN16057.13-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
maiAMaleate cis-trans isomerase; Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate. (249 aa)
ANN16121.12-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa)
ANN16295.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (255 aa)
ANN16429.1Fumarate reductase/succinate dehydrogenase flavoprotein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (638 aa)
ANN16430.1Succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
gabD2NADP-dependent semialdehyde dehydrogenase; part of alternative pathway from alpha-ketoglutarate to succinate; Derived by automated computational analysis using gene prediction method: Protein Homology. (537 aa)
ANN16530.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (261 aa)
ANN16579.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
ANN16584.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (383 aa)
ANN16601.1CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
ANN16602.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
ANN21745.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (387 aa)
ANN16610.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa)
ANN21746.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
ANN16682.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (551 aa)
ANN17175.1succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
gabD2-2NADP-dependent semialdehyde dehydrogenase; part of alternative pathway from alpha-ketoglutarate to succinate; Derived by automated computational analysis using gene prediction method: Protein Homology. (524 aa)
ANN17344.13-hydroxyisobutyryl-CoA hydrolase; Catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
ANN17424.13-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)
ANN17514.1Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (300 aa)
ANN17541.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
ANN18247.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (389 aa)
ANN18616.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
ANN18755.1Tartrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)
ANN19327.1Arylmalonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
ANN19350.13-oxoadipate--succinyl-CoA transferase subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
ANN19351.13-oxoadipate--succinyl-CoA transferase subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)
ANN19849.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (407 aa)
ANN20330.14-aminobutyrate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (443 aa)
ANN20541.1hydroxymethylglutaryl-CoA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
ANN20633.1Succinate dehydrogenase, cytochrome b556 subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (115 aa)
ANN20634.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)
ANN20635.1Succinate dehydrogenase flavoprotein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (584 aa)
ANN20636.1Succinate dehydrogenase iron-sulfur subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
ANN20896.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
ANN20897.12-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (635 aa)
ANN20898.12-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa)
ANN21056.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (540 aa)
ANN21220.1acetoacetate-CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (658 aa)
ANN21304.1Aminotransferase class III; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (427 aa)
Your Current Organism:
Amycolatopsis orientalis
NCBI taxonomy Id: 31958
Other names: A. orientalis, ATCC 19795, Actinoplanes sp. ATCC 53771, Amycolatopsis orientalis orientalis, Amycolatopsis orientalis subsp. orientalis, CIP 107113, DSM 40040, IFO 12806, IMSNU 20058, ISP 5040, JCM 4235, JCM 4600, KCTC 9412, NBRC 12806, NRRL 2450, Nocardia orientalis, Streptomyces orientalis, UNIQEM 181, VKM Ac-866
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