STRINGSTRING
eno eno Dgeo_0005 Dgeo_0005 Dgeo_0242 Dgeo_0242 Dgeo_0321 Dgeo_0321 Dgeo_0452 Dgeo_0452 Dgeo_0575 Dgeo_0575 deoB deoB Dgeo_0710 Dgeo_0710 rbsK rbsK tal tal Dgeo_1133 Dgeo_1133 pgk pgk tpiA tpiA Dgeo_1142 Dgeo_1142 rpiA rpiA deoC deoC pgi pgi Dgeo_1421 Dgeo_1421 pfkA pfkA Dgeo_1876 Dgeo_1876 Dgeo_2023 Dgeo_2023 Dgeo_2083 Dgeo_2083 Dgeo_2172 Dgeo_2172 Dgeo_2173 Dgeo_2173 Dgeo_2174 Dgeo_2174 Dgeo_2175 Dgeo_2175 Dgeo_2228 Dgeo_2228 apgM apgM Dgeo_2283 Dgeo_2283
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (422 aa)
Dgeo_0005PFAM: pyruvate kinase: (9.6e-166); KEGG: dra:DR2635 pyruvate kinase, ev=0.0, 86% identity; Belongs to the pyruvate kinase family. (482 aa)
Dgeo_0242ROK domain protein; PFAM: ROK: (1.7e-54); KEGG: dra:DR2296 glucokinase, ev=1e-128, 76% identity. (320 aa)
Dgeo_0321PFAM: mannose-6-phosphate isomerase, type I: (1.3e-09); KEGG: dra:DRA0048 mannose-6-phosphate isomerase, putative, ev=7e-94, 58% identity. (316 aa)
Dgeo_0452KEGG: dra:DR1456 ribose-phosphate pyrophosphokinase, ev=1e-156, 88% identity; TIGRFAM: ribose-phosphate pyrophosphokinase: (1.3e-120); PFAM: phosphoribosyltransferase: (2e-23). (355 aa)
Dgeo_0575ROK domain protein; PFAM: ROK: (5.5e-08); KEGG: dra:DR0823 ROK family protein, ev=1e-104, 77% identity. (270 aa)
deoBPhosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (392 aa)
Dgeo_0710TIGRFAM: D-3-phosphoglycerate dehydrogenase: (4.8e-212); PFAM: amino acid-binding ACT: (6.3e-07) D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region: (9.6e-40) D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding: (8.5e-87); KEGG: dra:DR1291 D-3-phosphoglycerate dehydrogenase, ev=0.0, 86% identity. (542 aa)
rbsKSugar kinase, ribokinase family; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (295 aa)
talTransaldolase, putative; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (246 aa)
Dgeo_1133KEGG: dra:DR1343 glyceraldehyde 3-phosphate dehydrogenase, ev=1e-158, 83% identity; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I: (1.8e-183); PFAM: glyceraldehyde 3-phosphate dehydrogenase: (1.3e-98); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (331 aa)
pgkPFAM: phosphoglycerate kinase: (1.8e-194); KEGG: dra:DR1342 phosphoglycerate kinase, ev=1e-172, 77% identity; Belongs to the phosphoglycerate kinase family. (389 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (244 aa)
Dgeo_1142Fructokinase RbsK; PFAM: PfkB: (2.1e-52); KEGG: dra:DR1525 carbohydrate kinase, PfkB family, ev=1e-133, 78% identity; Belongs to the carbohydrate kinase PfkB family. (310 aa)
rpiARibose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (228 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (409 aa)
pgiPFAM: phosphoglucose isomerase (PGI): (7.5e-272); KEGG: dra:DR1742 glucose-6-phosphate isomerase, ev=0.0, 77% identity. (649 aa)
Dgeo_1421Fructokinase, ScrK; PFAM: PfkB: (1.4e-47); KEGG: dra:DR0728 fructokinase, ev=1e-134, 78% identity. (284 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (336 aa)
Dgeo_1876TIGRFAM: fructose-1,6-bisphosphatase, class II: (2.5e-108); PFAM: GlpX: (5.6e-158); KEGG: ttj:TTHA1446 fructose-1,6-bisphosphatase, class II, ev=1e-127, 71% identity. (334 aa)
Dgeo_2023PFAM: Aldose 1-epimerase: (1.2e-31); KEGG: dra:DR0747 aldose epimerase family protein, ev=1e-120, 70% identity. (298 aa)
Dgeo_2083Fructose-1,6-bisphosphate aldolase, class II; KEGG: dra:DR1589 fructose-bisphosphate aldolase, ev=1e-152, 88% identity; TIGRFAM: ketose-bisphosphate aldolases: (5.7e-100) fructose-1,6-bisphosphate aldolase, class II: (6.8e-209); PFAM: ketose-bisphosphate aldolase, class-II: (1.9e-127). (308 aa)
Dgeo_2172Transcriptional regulator, DeoR family; PFAM: regulatory protein, DeoR: (1.6e-38) iron dependent repressor: (0.0018) Helix-turn-helix, type 11: (0.00086); KEGG: dra:DRB0076 glycerol-3-phosphate regulon repressor, ev=4e-95, 69% identity. (270 aa)
Dgeo_2173Phosphocarrier protein HPr / PTS system D-fructose-specific IIA component (F1P-forming), Frc family; TIGRFAM: Phosphoenolpyruvate-protein phosphotransferase: (4.6e-148); PFAM: phosphocarrier HPr protein: (1.8e-09) PEP-utilizing enzyme: (2e-132) phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2: (1.2e-60) PEP-utilising enzyme, mobile region: (5.7e-24) PEP-utilising enzyme-like: (1.5e-23); KEGG: dra:DRB0075 PTS system, multiphosphoryl transfer protein, domains EI, HPr, and fructose, ev=0.0, 74% identity; TC 4.A.2.1.1. (835 aa)
Dgeo_2174Fructose-1-phosphate kinase; PFAM: PfkB: (1.1e-53); KEGG: dra:DRB0074 1-phosphofructokinase, ev=1e-118, 71% identity; Belongs to the carbohydrate kinase PfkB family. (326 aa)
Dgeo_2175TIGRFAM: PTS system, fructose-specific, IIB component: (8.1e-56) Phosphotransferase system, fructose IIC component: (2.9e-130); PFAM: phosphotransferase system, EIIC: (1.5e-23) phosphotransferase system PTS, fructose-specific IIB subunit: (2e-58); KEGG: dra:DRB0073 PTS system, fructose-specific IIBC component, ev=0.0, 79% identity; TC 4.A.2.1.1; TC 4.A.2.1.1. (607 aa)
Dgeo_2228PFAM: Phosphoglycerate mutase: (1.1e-37); KEGG: dra:DR0602 phosphoglycerate mutase-related protein, ev=1e-70, 67% identity. (227 aa)
apgMPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (408 aa)
Dgeo_2283Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (667 aa)
Your Current Organism:
Deinococcus geothermalis
NCBI taxonomy Id: 319795
Other names: D. geothermalis DSM 11300, Deinococcus geothermalis AG-3a, Deinococcus geothermalis CIP 105573, Deinococcus geothermalis DSM 11300, Deinococcus geothermalis str. DSM 11300, Deinococcus geothermalis strain DSM 11300
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