STRINGSTRING
Dgeo_0054 Dgeo_0054 Dgeo_0055 Dgeo_0055 Dgeo_0056 Dgeo_0056 menG menG Dgeo_0059 Dgeo_0059 Dgeo_0060 Dgeo_0060 Dgeo_0061 Dgeo_0061 Dgeo_0279 Dgeo_0279 Dgeo_0475 Dgeo_0475 Dgeo_0537 Dgeo_0537 Dgeo_0538 Dgeo_0538 Dgeo_0539 Dgeo_0539 Dgeo_0540 Dgeo_0540 Dgeo_0541 Dgeo_0541 Dgeo_0542 Dgeo_0542 Dgeo_0544 Dgeo_0544 Dgeo_0572 Dgeo_0572 Dgeo_0589 Dgeo_0589 Dgeo_0590 Dgeo_0590 Dgeo_0591 Dgeo_0591 Dgeo_0611 Dgeo_0611 Dgeo_0658 Dgeo_0658 Dgeo_0659 Dgeo_0659 Dgeo_0660 Dgeo_0660 Dgeo_0662 Dgeo_0662 Dgeo_0666 Dgeo_0666 Dgeo_0667 Dgeo_0667 greA greA Dgeo_0669 Dgeo_0669 Dgeo_0671 Dgeo_0671 Dgeo_0672 Dgeo_0672 Dgeo_0686 Dgeo_0686 Dgeo_0687 Dgeo_0687 Dgeo_0725 Dgeo_0725 Dgeo_0747 Dgeo_0747 Dgeo_0748 Dgeo_0748 Dgeo_0749 Dgeo_0749 Dgeo_0750 Dgeo_0750 Dgeo_0751 Dgeo_0751 Dgeo_0752 Dgeo_0752 Dgeo_0753 Dgeo_0753 glgC glgC Dgeo_0904 Dgeo_0904 Dgeo_0905 Dgeo_0905 Dgeo_0906 Dgeo_0906 Dgeo_0907 Dgeo_0907 Dgeo_0941 Dgeo_0941 glgB glgB Dgeo_1059 Dgeo_1059 Dgeo_1065 Dgeo_1065 Dgeo_1079 Dgeo_1079 Dgeo_1167 Dgeo_1167 Dgeo_1168 Dgeo_1168 Dgeo_1169 Dgeo_1169 Dgeo_1170 Dgeo_1170 Dgeo_1171 Dgeo_1171 Dgeo_1172 Dgeo_1172 Dgeo_1173 Dgeo_1173 Dgeo_1175 Dgeo_1175 Dgeo_1176 Dgeo_1176 Dgeo_1177 Dgeo_1177 Dgeo_1198 Dgeo_1198 Dgeo_1500 Dgeo_1500 Dgeo_1501 Dgeo_1501 Dgeo_1502 Dgeo_1502 Dgeo_1578 Dgeo_1578 Dgeo_1875 Dgeo_1875 Dgeo_1878 Dgeo_1878 glgA glgA Dgeo_2104 Dgeo_2104 Dgeo_2242 Dgeo_2242 Dgeo_2243 Dgeo_2243 Dgeo_2244 Dgeo_2244
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Dgeo_0054KEGG: dra:DR2350 hypothetical protein, ev=3e-98, 52% identity. (644 aa)
Dgeo_0055KEGG: dra:DR2348 hypothetical protein, ev=1e-118, 47% identity. (529 aa)
Dgeo_0056PFAM: Roadblock/LC7: (3.3e-05); KEGG: dra:DR2347 hypothetical protein, ev=3e-61, 50% identity. (236 aa)
menGUbiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (239 aa)
Dgeo_0059Trehalose 6-phosphate synthase; PFAM: glycosyl transferase, family 20: (1.8e-186); KEGG: sru:SRU_0569 trehalose-6-phosphate synthase domain, putative, ev=1e-117, 47% identity. (457 aa)
Dgeo_0060Trehalose 6-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose. (238 aa)
Dgeo_0061Predicted membrane protein; KEGG: dra:DR2559 hypothetical protein, ev=3e-18, 54% identity. (80 aa)
Dgeo_0279KEGG: dra:DR2265 hypothetical protein, ev=0.0, 69% identity. (736 aa)
Dgeo_0475PFAM: alpha amylase, catalytic region: (5.5e-72); SMART: Alpha amylase, catalytic subdomain: (2e-92); KEGG: dra:DR0723 glycosyl hydrolase, family 13, ev=0.0, 63% identity. (608 aa)
Dgeo_0537KEGG: dra:DR2036 trehalose synthase, putative, ev=0.0, 84% identity; TIGRFAM: Trehalose synthase-like: (0); PFAM: alpha amylase, catalytic region: (1.5e-59); SMART: Alpha amylase, catalytic subdomain: (4e-106). (556 aa)
Dgeo_0538PFAM: protein of unknown function UPF0005: (6.1e-19); KEGG: dra:DR0893 conserved hypothetical protein, ev=6e-88, 77% identity; Belongs to the BI1 family. (228 aa)
Dgeo_0539KEGG: dra:DR0463 maltooligosyltrehalose synthase, ev=0.0, 69% identity; TIGRFAM: Malto-oligosyltrehalose synthase: (0); PFAM: alpha amylase, catalytic region: (3.4e-05); SMART: Alpha amylase, catalytic subdomain: (2.8e-09). (944 aa)
Dgeo_0540KEGG: dra:DR0464 maltooligosyltrehalose trehalohydrolase, putative, ev=0.0, 68% identity; TIGRFAM: Malto-oligosyltrehalose trehalohydrolase: (2.9e-289); PFAM: glycoside hydrolase, family 13-like: (1.8e-12) alpha amylase, catalytic region: (4e-09); SMART: Alpha amylase, catalytic subdomain: (9.6e-12). (603 aa)
Dgeo_0541Isoamylase; KEGG: dra:DR0264 glycogen operon protein GlgX, ev=0.0, 84% identity; TIGRFAM: Glycogen debranching enzyme GlgX: (0); PFAM: glycoside hydrolase, family 13-like: (1.1e-35) alpha amylase, catalytic region: (1.9e-15); SMART: Alpha amylase, catalytic subdomain: (1.2e-11); Belongs to the glycosyl hydrolase 13 family. (727 aa)
Dgeo_0542KEGG: dra:DR1693 hypothetical protein, ev=4e-58, 69% identity. (184 aa)
Dgeo_0544Predicted periplasmic protein; KEGG: dra:DR1818 hypothetical protein, ev=2e-19, 44% identity. (154 aa)
Dgeo_0572Amylosucrase; PFAM: alpha amylase, catalytic region: (2.5e-20); SMART: Alpha amylase, catalytic subdomain: (2.7e-36); KEGG: dra:DR0933 alpha-amlyase, ev=0.0, 74% identity. (650 aa)
Dgeo_0589PFAM: binding-protein-dependent transport systems inner membrane component: (1.1e-22); KEGG: dra:DR1436 putative multiple sugar transport system permease protein, ev=1e-129, 82% identity. (283 aa)
Dgeo_0590PFAM: binding-protein-dependent transport systems inner membrane component: (2.2e-09); KEGG: dra:DR1437 putative multiple sugar transport system permease protein, ev=1e-153, 84% identity. (315 aa)
Dgeo_0591Trehalose/maltose transport system substrate-binding protein; PFAM: extracellular solute-binding protein, family 1: (3.2e-45); KEGG: dra:DR1438 putative multiple sugar transport system substrate-binding protein, ev=0.0, 82% identity. (421 aa)
Dgeo_0611Isoamylase / pullulanase; PFAM: alpha amylase, catalytic region: (3.5e-93); SMART: Alpha amylase, catalytic subdomain: (1.1e-106); KEGG: dra:DR1141 glycosyl hydrolase, family 13, ev=0.0, 72% identity. (496 aa)
Dgeo_0658Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR: (2.5e-13); KEGG: betI; regulatory protein BetI, ev=4e-14, 35% identity. (195 aa)
Dgeo_0659Chloride channel protein, EriC; PFAM: Cl- channel, voltage gated: (2.3e-07) TrkA-C: (6.9e-09); KEGG: dra:DR1752 hypothetical protein, ev=0.0, 63% identity. (543 aa)
Dgeo_0660PFAM: alpha amylase, catalytic region: (4.8e-71); SMART: Alpha amylase, catalytic subdomain: (3.1e-89); KEGG: dra:DR1472 glycosyl hydrolase, family 13, ev=0.0, 71% identity. (484 aa)
Dgeo_0662PFAM: metallophosphoesterase: (1.1e-10); KEGG: dra:DR1281 hypothetical protein, ev=1e-106, 71% identity. (263 aa)
Dgeo_0666TIGRFAM: ATP: (4.1e-106); PFAM: cobalamin adenosyltransferase: (8.8e-91); KEGG: dra:DR1638 hypothetical protein, ev=1e-78, 77% identity; Belongs to the Cob(I)alamin adenosyltransferase family. (190 aa)
Dgeo_0667KEGG: ttj:TTHA1261 4-alpha-glucanotransferase (amylomaltase) (disproportionating enzyme) (D-enzyme), ev=1e-159, 55% identity; TIGRFAM: 4-alpha-glucanotransferase: (4.9e-109); PFAM: glycoside hydrolase, family 77: (7.7e-217). (503 aa)
greATranscription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. (156 aa)
Dgeo_0669Pilus retraction ATPase PilT; KEGG: dra:DR1163 twitching motility protein, ev=1e-152, 74% identity; TIGRFAM: twitching motility protein: (4.5e-227); PFAM: type II secretion system protein E: (4.1e-20); SMART: ATPase: (7.8e-06). (358 aa)
Dgeo_0671PFAM: membrane protein of unknown function: (1.7e-50); KEGG: dra:DR1165 hypothetical protein, ev=2e-48, 79% identity. (122 aa)
Dgeo_0672PFAM: alpha amylase, catalytic region: (4.5e-114); SMART: Alpha amylase, catalytic subdomain: (4.1e-148); KEGG: dra:DR1375 alpha-glucosidase, ev=0.0, 77% identity. (533 aa)
Dgeo_0686PFAM: glycoside hydrolase, family 20: (2.6e-09); KEGG: blo:BL0056 possible beta-hexosaminidase A, ev=1e-15, 23% identity. (673 aa)
Dgeo_0687PFAM: extracellular solute-binding protein, family 1: (2e-30); KEGG: cvi:CV2897 probable sugar ABC transporter periplasmic sugar-binding protein, ev=2e-69, 37% identity; TC 3.A.1.1.-. (407 aa)
Dgeo_0725Glucan 1,4-alpha-glucosidase; PFAM: glycoside hydrolase 15-related: (1.9e-32); KEGG: mlo:mlr4205 glucoamylase, (glucan 1,4-alpha-glucosidase), ev=1e-150, 42% identity. (798 aa)
Dgeo_0747PFAM: DSBA oxidoreductase: (9e-08); KEGG: dra:DR2019 hypothetical protein, ev=2e-78, 49% identity. (335 aa)
Dgeo_0748PFAM: Amylo-alpha-1,6-glucosidase: (7.4e-06); KEGG: reu:Reut_A0692 amylo-alpha-1,6-glucosidase, ev=1e-99, 40% identity. (628 aa)
Dgeo_0749Carbohydrate ABC transporter membrane protein 2, CUT1 family; PFAM: binding-protein-dependent transport systems inner membrane component: (8.2e-13); KEGG: sme:SMa1362 putative inner-membrane permease, ev=2e-80, 37% identity; TC 3.A.1.1.-. (514 aa)
Dgeo_0750Carbohydrate ABC transporter membrane protein 1, CUT1 family; PFAM: binding-protein-dependent transport systems inner membrane component: (0.0033); KEGG: sme:SMa1363 putative ABC transporter, permease protein, ev=7e-78, 45% identity; TC 3.A.1.1.-. (366 aa)
Dgeo_0751PFAM: extracellular solute-binding protein, family 1: (1.1e-28); KEGG: sme:SMa1364 putative ABC transporter, periplasmic solute-binding protein, ev=9e-93, 44% identity; TC 3.A.1.1.-. (411 aa)
Dgeo_0752Transcriptional regulator, LacI family; PFAM: regulatory protein, LacI: (7.6e-11) periplasmic binding protein/LacI transcriptional regulator: (6e-05); KEGG: sma:SAV554 putative LacI-family transcriptional regulator, ev=3e-33, 35% identity. (331 aa)
Dgeo_0753PFAM: Alcohol dehydrogenase, zinc-binding: (6.9e-35) Alcohol dehydrogenase GroES-like: (3.1e-27); KEGG: dra:DR1061 NADPH quinone oxidoreductase, putative, ev=1e-134, 73% identity. (329 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (413 aa)
Dgeo_0904ROK domain protein; PFAM: ROK: (2e-32); KEGG: sma:SAV2248 putative ROK-family transcriptional regulator, ev=6e-60, 39% identity. (408 aa)
Dgeo_0905Glucose-binding protein / mannose-binding protein; PFAM: extracellular solute-binding protein, family 1: (2.6e-16); KEGG: ttj:TTHA0688 sugar ABC transporter, substrate-binding protein, ev=1e-176, 68% identity. (412 aa)
Dgeo_0906Glucose ABC transporter membrane protein / mannose ABC transporter membrane protein; PFAM: binding-protein-dependent transport systems inner membrane component: (2.2e-11); KEGG: tth:TTC0327 glucose transport system permease protein, ev=1e-127, 60% identity. (383 aa)
Dgeo_0907PFAM: binding-protein-dependent transport systems inner membrane component: (5.7e-19); KEGG: ttj:TTHA0685 sugar ABC transporter, permease protein, ev=1e-108, 71% identity. (287 aa)
Dgeo_0941Lactoylglutathione lyase and esterase family domains; PFAM: dienelactone hydrolase: (0.0002) phospholipase/Carboxylesterase: (6.8e-16) Glyoxalase/bleomycin resistance protein/dioxygenase: (2.2e-08); KEGG: bja:bll3247 dioxygenase, ev=2e-81, 52% identity. (552 aa)
glgB1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (652 aa)
Dgeo_1059Carbohydrate ABC transporter ATP-binding protein, CUT1 family; PFAM: ABC transporter related: (2.4e-57) TOBE: (6.6e-15) Transport-associated OB: (9.6e-13); SMART: ATPase: (1.1e-16); KEGG: dra:DR2153 putative polar amino acid transport system ATP-binding protein, ev=0.0, 82% identity; TC 3.A.1.1.-. (402 aa)
Dgeo_1065PFAM: major facilitator superfamily MFS_1: (2e-07); KEGG: ttj:TTHA0314 hypothetical protein, ev=1e-66, 40% identity. (419 aa)
Dgeo_1079Beta-N-acetylhexosaminidase; PFAM: glycoside hydrolase, family 3-like: (4.6e-42); KEGG: dra:DR1333 glycosyl hyrolase, family 3, ev=1e-136, 75% identity. (478 aa)
Dgeo_1167KEGG: dra:DR1539 hypothetical protein, ev=3e-18, 55% identity. (89 aa)
Dgeo_1168Carbohydrate ABC transporter membrane protein 1, CUT1 family; PFAM: binding-protein-dependent transport systems inner membrane component: (3.2e-11); KEGG: cvi:CV2898 probable sugar ABC transporter permease protein, ev=9e-84, 53% identity; TC 3.A.1.1.-. (310 aa)
Dgeo_1169Carbohydrate ABC transporter membrane protein 2, CUT1 family; PFAM: binding-protein-dependent transport systems inner membrane component: (3.5e-13); KEGG: cvi:CV0260 probable ABC transporter sugar permease, ev=5e-63, 45% identity; TC 3.A.1.1.-. (306 aa)
Dgeo_11702-oxoacid dehydrogenase; KEGG: bcl:ABC3582 hypothetical protein, ev=2e-59, 35% identity. (457 aa)
Dgeo_1171Hydrolase of the alpha/beta superfamily; KEGG: dra:DR1064 hypothetical protein, ev=6e-50, 69% identity. (258 aa)
Dgeo_1172KEGG: tte:TTE2409 hypothetical protein, ev=9e-57, 30% identity. (497 aa)
Dgeo_1173ROK domain protein; PFAM: ROK: (3e-27); KEGG: stt:t3253 putative N-acetylmannosamine kinase, ev=6e-42, 40% identity. (298 aa)
Dgeo_1175Yfit/DinB family predicted metal-dependent hydrolase; KEGG: dra:DR1641 hypothetical protein, ev=8e-75, 79% identity. (168 aa)
Dgeo_1176Aminoglycoside phosphotransferase family protein; KEGG: dra:DR1644 hypothetical protein, ev=2e-54, 55% identity. (294 aa)
Dgeo_1177PFAM: aminotransferase class-III: (1.6e-89); KEGG: dra:DRA0121 aminotransferase, class III, ev=1e-179, 74% identity; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (444 aa)
Dgeo_1198KEGG: dra:DR2195 alpha-glucan phosphorylase, putative, ev=0.0, 77% identity; TIGRFAM: Alpha-glucan phosphorylase: (0); PFAM: glycosyl transferase, family 35: (0.00028). (842 aa)
Dgeo_1500Carbohydrate ABC transporter substrate-binding protein, CUT1 family; PFAM: extracellular solute-binding protein, family 1: (1.3e-32); KEGG: dra:DR0561 maltose transport system substrate-binding protein, ev=1e-166, 70% identity; TC 3.A.1.1.-. (393 aa)
Dgeo_1501Carbohydrate ABC transporter membrane protein 1, CUT1 family; PFAM: binding-protein-dependent transport systems inner membrane component: (2.1e-13); KEGG: dra:DR0562 maltose transport system permease protein, ev=0.0, 72% identity; TC 3.A.1.1.-. (474 aa)
Dgeo_1502Carbohydrate ABC transporter membrane protein 2, CUT1 family; PFAM: binding-protein-dependent transport systems inner membrane component: (1.1e-19); KEGG: dra:DR0563 maltose transport system permease protein, ev=0.0, 76% identity; TC 3.A.1.1.-. (458 aa)
Dgeo_1578PFAM: oxidoreductase-like: (5e-36) Oxidoreductase-like: (2.5e-06); KEGG: bcl:ABC2696 oxidoreductase, ev=1e-43, 36% identity. (327 aa)
Dgeo_1875TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific: (0); PFAM: phosphoglucomutase/phosphomannomutase C terminal: (2.9e-12) phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I: (1.1e-35) phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II: (2.5e-17) phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III: (1.9e-32); KEGG: pca:Pcar_1989 phosphoglucomutase, alpha-D-glucose phosphate-specific, ev=0.0, 61% identity. (547 aa)
Dgeo_1878Flavodoxin/nitric oxide synthase; PFAM: NADPH-dependent FMN reductase: (0.00068) flavodoxin/nitric oxide synthase: (1.2e-09); KEGG: dra:DRA0214 trp repressor binding protein WrbA, putative, ev=1e-82, 76% identity; Belongs to the WrbA family. (202 aa)
glgAGlycogen synthase (ADP-glucose); Synthesizes alpha-1,4-glucan chains using ADP-glucose. (447 aa)
Dgeo_2104PFAM: glycoside hydrolase family 2, immunoglobulin-like beta-sandwich: (0.0013) glycoside hydrolase family 2, TIM barrel: (1.4e-06) glycoside hydrolase family 2, sugar binding: (2.2e-27); KEGG: nmu:Nmul_A1940 glycoside hydrolase family 2, sugar binding, ev=1e-161, 47% identity; Belongs to the glycosyl hydrolase 2 family. (627 aa)
Dgeo_2242TIGRFAM: UDP-glucose 4-epimerase: (1.3e-209); PFAM: NAD-dependent epimerase/dehydratase: (7.7e-77) 3-beta hydroxysteroid dehydrogenase/isomerase: (1.1e-09) polysaccharide biosynthesis protein CapD: (0.00025) dTDP-4-dehydrorhamnose reductase: (1.5e-07) Male sterility-like: (1.4e-06); KEGG: dra:DR2202 UDP-glucose 4-epimerase, ev=1e-155, 80% identity; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (334 aa)
Dgeo_2243Transcriptional regulator, LacI family; PFAM: regulatory protein, LacI: (1.4e-05) periplasmic binding protein/LacI transcriptional regulator: (3.1e-09); KEGG: dra:DR2501 transcriptional regulator, sugar-binding, putative, ev=1e-96, 59% identity. (339 aa)
Dgeo_2244PFAM: major facilitator superfamily MFS_1: (1.4e-20); KEGG: dra:DR2502 transport protein, putative, ev=1e-146, 71% identity. (400 aa)
Your Current Organism:
Deinococcus geothermalis
NCBI taxonomy Id: 319795
Other names: D. geothermalis DSM 11300, Deinococcus geothermalis AG-3a, Deinococcus geothermalis CIP 105573, Deinococcus geothermalis DSM 11300, Deinococcus geothermalis str. DSM 11300, Deinococcus geothermalis strain DSM 11300
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