| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Dgeo_1546 | fmt | Dgeo_1546 | Dgeo_2291 | PFAM: formyl transferase-like: (3.1e-40); KEGG: dra:DR2026 phosphoribosylglycinamide formyltransferase, ev=1e-78, 80% identity. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.940 |
| Dgeo_1546 | gcvT | Dgeo_1546 | Dgeo_1905 | PFAM: formyl transferase-like: (3.1e-40); KEGG: dra:DR2026 phosphoribosylglycinamide formyltransferase, ev=1e-78, 80% identity. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.932 |
| Dgeo_1546 | glyA | Dgeo_1546 | Dgeo_0221 | PFAM: formyl transferase-like: (3.1e-40); KEGG: dra:DR2026 phosphoribosylglycinamide formyltransferase, ev=1e-78, 80% identity. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.965 |
| Dgeo_1546 | purH | Dgeo_1546 | Dgeo_0513 | PFAM: formyl transferase-like: (3.1e-40); KEGG: dra:DR2026 phosphoribosylglycinamide formyltransferase, ev=1e-78, 80% identity. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; KEGG: dra:DR0868 phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.999 |
| Dgeo_1546 | purU | Dgeo_1546 | Dgeo_1488 | PFAM: formyl transferase-like: (3.1e-40); KEGG: dra:DR2026 phosphoribosylglycinamide formyltransferase, ev=1e-78, 80% identity. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.932 |
| fmt | Dgeo_1546 | Dgeo_2291 | Dgeo_1546 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | PFAM: formyl transferase-like: (3.1e-40); KEGG: dra:DR2026 phosphoribosylglycinamide formyltransferase, ev=1e-78, 80% identity. | 0.940 |
| fmt | gcvT | Dgeo_2291 | Dgeo_1905 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.931 |
| fmt | glyA | Dgeo_2291 | Dgeo_0221 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.927 |
| gcvT | Dgeo_1546 | Dgeo_1905 | Dgeo_1546 | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | PFAM: formyl transferase-like: (3.1e-40); KEGG: dra:DR2026 phosphoribosylglycinamide formyltransferase, ev=1e-78, 80% identity. | 0.932 |
| gcvT | fmt | Dgeo_1905 | Dgeo_2291 | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.931 |
| gcvT | glyA | Dgeo_1905 | Dgeo_0221 | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.996 |
| gcvT | purH | Dgeo_1905 | Dgeo_0513 | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; KEGG: dra:DR0868 phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.943 |
| gcvT | purU | Dgeo_1905 | Dgeo_1488 | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.924 |
| glyA | Dgeo_1546 | Dgeo_0221 | Dgeo_1546 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | PFAM: formyl transferase-like: (3.1e-40); KEGG: dra:DR2026 phosphoribosylglycinamide formyltransferase, ev=1e-78, 80% identity. | 0.965 |
| glyA | fmt | Dgeo_0221 | Dgeo_2291 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.927 |
| glyA | gcvT | Dgeo_0221 | Dgeo_1905 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.996 |
| glyA | purH | Dgeo_0221 | Dgeo_0513 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; KEGG: dra:DR0868 phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.990 |
| glyA | purU | Dgeo_0221 | Dgeo_1488 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.937 |
| purH | Dgeo_1546 | Dgeo_0513 | Dgeo_1546 | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; KEGG: dra:DR0868 phosphoribosylaminoimidazolecarboxamide formyltransferase. | PFAM: formyl transferase-like: (3.1e-40); KEGG: dra:DR2026 phosphoribosylglycinamide formyltransferase, ev=1e-78, 80% identity. | 0.999 |
| purH | gcvT | Dgeo_0513 | Dgeo_1905 | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; KEGG: dra:DR0868 phosphoribosylaminoimidazolecarboxamide formyltransferase. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.943 |