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Dgeo_0203 Dgeo_0203 Dgeo_0353 Dgeo_0353 Dgeo_0618 Dgeo_0618 Dgeo_0736 Dgeo_0736 Dgeo_0755 Dgeo_0755 Dgeo_0808 Dgeo_0808 Dgeo_0809 Dgeo_0809 Dgeo_0862 Dgeo_0862 Dgeo_1081 Dgeo_1081 Dgeo_1306 Dgeo_1306 Dgeo_1320 Dgeo_1320 Dgeo_1441 Dgeo_1441 Dgeo_1541 Dgeo_1541 Dgeo_1790 Dgeo_1790 Dgeo_1883 Dgeo_1883 Dgeo_2162 Dgeo_2162 Dgeo_2323 Dgeo_2323 Dgeo_2338 Dgeo_2338 Dgeo_2339 Dgeo_2339
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Dgeo_0203PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal: (5.6e-13) Glu/Leu/Phe/Val dehydrogenase, dimerisation region: (3.7e-10); KEGG: dra:DR0158 leucine dehydrogenase, ev=1e-151, 78% identity; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (344 aa)
Dgeo_0353TIGRFAM: Dihydrolipoamide dehydrogenase: (1.1e-231); PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase: (3e-29) glucose-inhibited division protein A: (0.00016) fumarate reductase/succinate dehydrogenase flavoprotein-like: (0.0029) pyridine nucleotide-disulphide oxidoreductase dimerisation region: (6.2e-64) HI0933-like protein: (0.001); KEGG: dra:DR2526 lipoamide dehydrogenase E3 component, ev=0.0, 83% identity. (468 aa)
Dgeo_0618Acetyl-CoA C-acyltransferase; PFAM: Thiolase: (4.5e-110) 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal: (0.0025); KEGG: dra:DR2480 acetyl-CoA acetyltransferase, ev=0.0, 87% identity; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
Dgeo_0736PFAM: acyl-CoA dehydrogenase-like: (3.1e-75) Acyl-CoA dehydrogenase, type 2-like: (1.9e-25); KEGG: dra:DR1318 acyl-CoA dehydrogenase, ev=0.0, 89% identity. (379 aa)
Dgeo_0755PFAM: Thiolase: (8.4e-92); KEGG: dra:DR1428 acetyl-CoA acetyltransferase, ev=0.0, 85% identity; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
Dgeo_0808KEGG: dra:DRA0068 3-oxoacid CoA-transferase subunit A, ev=1e-116, 89% identity; TIGRFAM: 3-oxoacid CoA-transferase, subunit A: (6.8e-97); PFAM: coenzyme A transferase: (4.1e-108). (244 aa)
Dgeo_0809KEGG: dra:DRA0067 3-oxoacid CoA-transferase subunit B, ev=1e-106, 93% identity; TIGRFAM: 3-oxoacid CoA-transferase, subunit B: (5e-162); PFAM: coenzyme A transferase: (2.1e-63). (209 aa)
Dgeo_0862KEGG: dra:DR1189 methylmalonyl-CoA mutase, alpha subunit, chain A, ev=0.0, 91% identity; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain: (8.1e-224); PFAM: methylmalonyl-CoA mutase: (1.8e-235). (548 aa)
Dgeo_1081PFAM: NADP oxidoreductase, coenzyme F420-dependent: (0.0017) 6-phosphogluconate dehydrogenase, NAD-binding: (1.2e-49); KEGG: dra:DR0499 3-hydroxyisobutyrate dehydrogenase, ev=1e-104, 68% identity. (295 aa)
Dgeo_1306KEGG: dra:DRA0054 3-oxoacid CoA-transferase, ev=0.0, 82% identity; TIGRFAM: 3-oxoacid CoA-transferase, subunit B: (6.2e-137) 3-oxoacid CoA-transferase, subunit A: (4.9e-69); PFAM: coenzyme A transferase: (7.4e-43); Belongs to the 3-oxoacid CoA-transferase family. (453 aa)
Dgeo_1320KEGG: dra:DR1084 methylmalonyl-CoA mutase, beta subunit, ev=0.0, 85% identity; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain: (5.2e-273) methylmalonyl-CoA mutase C-terminal domain: (6.1e-60); PFAM: methylmalonyl-CoA mutase: (0) cobalamin B12-binding: (7.7e-28). (722 aa)
Dgeo_1441PFAM: Thiolase: (6.2e-154); KEGG: dra:DR1072 acetyl-CoA acetyltransferase, ev=0.0, 82% identity; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
Dgeo_1541methylmalonyl-CoA mutase, alpha subunit; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain: (5.3e-45); PFAM: cobalamin B12-binding: (1.7e-41); KEGG: dra:DR2032 methylmalonyl-CoA mutase, alpha subunit, chain B, ev=1e-60, 85% identity. (151 aa)
Dgeo_1790PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase: (2.8e-11); KEGG: dra:DR2022 hypothetical protein, ev=3e-59, 77% identity. (158 aa)
Dgeo_1883PFAM: Thiolase: (7e-144); KEGG: dra:DR1960 acetyl-CoA acetyltransferase, ev=1e-163, 73% identity; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
Dgeo_2162PFAM: Enoyl-CoA hydratase/isomerase: (8.7e-23); KEGG: dra:DR0184 enoyl-CoA hydratase, putative, ev=1e-132, 84% identity; Belongs to the enoyl-CoA hydratase/isomerase family. (273 aa)
Dgeo_2323TIGRFAM: Dihydrolipoamide dehydrogenase: (3.5e-224); PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase: (4.7e-29) pyridine nucleotide-disulphide oxidoreductase dimerisation region: (2.7e-62); KEGG: dra:DR2370 pyruvate dehydrogenase complex, dihydrolipoamide dehydrogenase E3 component, putative, ev=0.0, 82% identity. (467 aa)
Dgeo_23382-oxoisovalerate dehydrogenase, OdbA; PFAM: dehydrogenase, E1 component: (4.7e-84); KEGG: dra:DR0029 2-oxoisovalerate dehydrogenase alpha subunit, ev=1e-166, 75% identity. (369 aa)
Dgeo_23392-oxoisovalerate dehydrogenase, ODBB; PFAM: Transketolase, central region: (1.4e-85) Transketolase-like: (9.6e-47); KEGG: dra:DR0030 2-oxoisovalerate dehydrogenase beta subunit, ev=1e-155, 79% identity. (340 aa)
Your Current Organism:
Deinococcus geothermalis
NCBI taxonomy Id: 319795
Other names: D. geothermalis DSM 11300, Deinococcus geothermalis AG-3a, Deinococcus geothermalis CIP 105573, Deinococcus geothermalis DSM 11300, Deinococcus geothermalis str. DSM 11300, Deinococcus geothermalis strain DSM 11300
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