STRINGSTRING
glmS glmS Dgeo_0242 Dgeo_0242 Dgeo_0321 Dgeo_0321 Dgeo_0341 Dgeo_0341 Dgeo_0575 Dgeo_0575 Dgeo_0686 Dgeo_0686 glgC glgC Dgeo_1079 Dgeo_1079 Dgeo_1173 Dgeo_1173 Dgeo_1294 Dgeo_1294 pgi pgi murA murA Dgeo_1421 Dgeo_1421 murB murB glmM glmM Dgeo_1875 Dgeo_1875 glmU glmU Dgeo_2242 Dgeo_2242
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
glmSGlutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (606 aa)
Dgeo_0242ROK domain protein; PFAM: ROK: (1.7e-54); KEGG: dra:DR2296 glucokinase, ev=1e-128, 76% identity. (320 aa)
Dgeo_0321PFAM: mannose-6-phosphate isomerase, type I: (1.3e-09); KEGG: dra:DRA0048 mannose-6-phosphate isomerase, putative, ev=7e-94, 58% identity. (316 aa)
Dgeo_0341Mannose-6-phosphate isomerase, type 2; PFAM: Nucleotidyl transferase: (3.2e-70); KEGG: dra:DRA0032 mannose-1-phosphate guanylyltransferase, ev=1e-157, 76% identity. (359 aa)
Dgeo_0575ROK domain protein; PFAM: ROK: (5.5e-08); KEGG: dra:DR0823 ROK family protein, ev=1e-104, 77% identity. (270 aa)
Dgeo_0686PFAM: glycoside hydrolase, family 20: (2.6e-09); KEGG: blo:BL0056 possible beta-hexosaminidase A, ev=1e-15, 23% identity. (673 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (413 aa)
Dgeo_1079Beta-N-acetylhexosaminidase; PFAM: glycoside hydrolase, family 3-like: (4.6e-42); KEGG: dra:DR1333 glycosyl hyrolase, family 3, ev=1e-136, 75% identity. (478 aa)
Dgeo_1173ROK domain protein; PFAM: ROK: (3e-27); KEGG: stt:t3253 putative N-acetylmannosamine kinase, ev=6e-42, 40% identity. (298 aa)
Dgeo_1294PFAM: UDP-N-acetylglucosamine 2-epimerase: (4e-100); KEGG: dra:DR1561 UDP-N-acetylglucosamine 2-epimerase, ev=1e-177, 84% identity; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (385 aa)
pgiPFAM: phosphoglucose isomerase (PGI): (7.5e-272); KEGG: dra:DR1742 glucose-6-phosphate isomerase, ev=0.0, 77% identity. (649 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (427 aa)
Dgeo_1421Fructokinase, ScrK; PFAM: PfkB: (1.4e-47); KEGG: dra:DR0728 fructokinase, ev=1e-134, 78% identity. (284 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (295 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (444 aa)
Dgeo_1875TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific: (0); PFAM: phosphoglucomutase/phosphomannomutase C terminal: (2.9e-12) phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I: (1.1e-35) phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II: (2.5e-17) phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III: (1.9e-32); KEGG: pca:Pcar_1989 phosphoglucomutase, alpha-D-glucose phosphate-specific, ev=0.0, 61% identity. (547 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (481 aa)
Dgeo_2242TIGRFAM: UDP-glucose 4-epimerase: (1.3e-209); PFAM: NAD-dependent epimerase/dehydratase: (7.7e-77) 3-beta hydroxysteroid dehydrogenase/isomerase: (1.1e-09) polysaccharide biosynthesis protein CapD: (0.00025) dTDP-4-dehydrorhamnose reductase: (1.5e-07) Male sterility-like: (1.4e-06); KEGG: dra:DR2202 UDP-glucose 4-epimerase, ev=1e-155, 80% identity; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (334 aa)
Your Current Organism:
Deinococcus geothermalis
NCBI taxonomy Id: 319795
Other names: D. geothermalis DSM 11300, Deinococcus geothermalis AG-3a, Deinococcus geothermalis CIP 105573, Deinococcus geothermalis DSM 11300, Deinococcus geothermalis str. DSM 11300, Deinococcus geothermalis strain DSM 11300
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