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pta pta ackA ackA mgsA mgsA Dgeo_0353 Dgeo_0353 Dgeo_0466 Dgeo_0466 Dgeo_0467 Dgeo_0467 Dgeo_0755 Dgeo_0755 Dgeo_0862 Dgeo_0862 argD argD sucC sucC sucD sucD Dgeo_1229 Dgeo_1229 Dgeo_1320 Dgeo_1320 Dgeo_1441 Dgeo_1441 Dgeo_1541 Dgeo_1541 Dgeo_1750 Dgeo_1750 acsA acsA Dgeo_1790 Dgeo_1790 Dgeo_1883 Dgeo_1883 Dgeo_2162 Dgeo_2162 accA accA accD accD Dgeo_2323 Dgeo_2323 Dgeo_2338 Dgeo_2338 Dgeo_2339 Dgeo_2339
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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ptaPhosphate acetyltransferase; Involved in acetate metabolism; In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family. (703 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (395 aa)
mgsAMethylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (137 aa)
Dgeo_0353TIGRFAM: Dihydrolipoamide dehydrogenase: (1.1e-231); PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase: (3e-29) glucose-inhibited division protein A: (0.00016) fumarate reductase/succinate dehydrogenase flavoprotein-like: (0.0029) pyridine nucleotide-disulphide oxidoreductase dimerisation region: (6.2e-64) HI0933-like protein: (0.001); KEGG: dra:DR2526 lipoamide dehydrogenase E3 component, ev=0.0, 83% identity. (468 aa)
Dgeo_0466acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (445 aa)
Dgeo_0467acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (177 aa)
Dgeo_0755PFAM: Thiolase: (8.4e-92); KEGG: dra:DR1428 acetyl-CoA acetyltransferase, ev=0.0, 85% identity; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
Dgeo_0862KEGG: dra:DR1189 methylmalonyl-CoA mutase, alpha subunit, chain A, ev=0.0, 91% identity; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain: (8.1e-224); PFAM: methylmalonyl-CoA mutase: (1.8e-235). (548 aa)
argDPFAM: aminotransferase class-III: (6.4e-141); KEGG: dra:DRA0029 4-aminobutyrate aminotransferase, ev=0.0, 82% identity; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (458 aa)
sucCsuccinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (385 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (303 aa)
Dgeo_1229PFAM: Alcohol dehydrogenase, zinc-binding: (2.8e-16) Alcohol dehydrogenase GroES-like: (3.8e-16); KEGG: rpa:RPA4658 zinc-binding dehydrogenase (related to alcohol dehydrogenase, NADPH quinone oxidoreductase), ev=4e-96, 56% identity. (342 aa)
Dgeo_1320KEGG: dra:DR1084 methylmalonyl-CoA mutase, beta subunit, ev=0.0, 85% identity; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain: (5.2e-273) methylmalonyl-CoA mutase C-terminal domain: (6.1e-60); PFAM: methylmalonyl-CoA mutase: (0) cobalamin B12-binding: (7.7e-28). (722 aa)
Dgeo_1441PFAM: Thiolase: (6.2e-154); KEGG: dra:DR1072 acetyl-CoA acetyltransferase, ev=0.0, 82% identity; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
Dgeo_1541methylmalonyl-CoA mutase, alpha subunit; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain: (5.3e-45); PFAM: cobalamin B12-binding: (1.7e-41); KEGG: dra:DR2032 methylmalonyl-CoA mutase, alpha subunit, chain B, ev=1e-60, 85% identity. (151 aa)
Dgeo_1750PFAM: AMP-dependent synthetase and ligase: (5.5e-117); KEGG: dra:DR0460 acetyl-CoA synthase, ev=0.0, 78% identity. (636 aa)
acsAAcetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (655 aa)
Dgeo_1790PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase: (2.8e-11); KEGG: dra:DR2022 hypothetical protein, ev=3e-59, 77% identity. (158 aa)
Dgeo_1883PFAM: Thiolase: (7e-144); KEGG: dra:DR1960 acetyl-CoA acetyltransferase, ev=1e-163, 73% identity; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
Dgeo_2162PFAM: Enoyl-CoA hydratase/isomerase: (8.7e-23); KEGG: dra:DR0184 enoyl-CoA hydratase, putative, ev=1e-132, 84% identity; Belongs to the enoyl-CoA hydratase/isomerase family. (273 aa)
accAacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (306 aa)
accDacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (284 aa)
Dgeo_2323TIGRFAM: Dihydrolipoamide dehydrogenase: (3.5e-224); PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase: (4.7e-29) pyridine nucleotide-disulphide oxidoreductase dimerisation region: (2.7e-62); KEGG: dra:DR2370 pyruvate dehydrogenase complex, dihydrolipoamide dehydrogenase E3 component, putative, ev=0.0, 82% identity. (467 aa)
Dgeo_23382-oxoisovalerate dehydrogenase, OdbA; PFAM: dehydrogenase, E1 component: (4.7e-84); KEGG: dra:DR0029 2-oxoisovalerate dehydrogenase alpha subunit, ev=1e-166, 75% identity. (369 aa)
Dgeo_23392-oxoisovalerate dehydrogenase, ODBB; PFAM: Transketolase, central region: (1.4e-85) Transketolase-like: (9.6e-47); KEGG: dra:DR0030 2-oxoisovalerate dehydrogenase beta subunit, ev=1e-155, 79% identity. (340 aa)
Your Current Organism:
Deinococcus geothermalis
NCBI taxonomy Id: 319795
Other names: D. geothermalis DSM 11300, Deinococcus geothermalis AG-3a, Deinococcus geothermalis CIP 105573, Deinococcus geothermalis DSM 11300, Deinococcus geothermalis str. DSM 11300, Deinococcus geothermalis strain DSM 11300
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