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| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (422 aa) |
| | Dgeo_0005 | PFAM: pyruvate kinase: (9.6e-166); KEGG: dra:DR2635 pyruvate kinase, ev=0.0, 86% identity; Belongs to the pyruvate kinase family. (482 aa) |
| | pta | Phosphate acetyltransferase; Involved in acetate metabolism; In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family. (703 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (395 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (309 aa) |
| | Dgeo_0139 | 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (425 aa) |
| | Dgeo_0140 | KEGG: dra:DR0287 2-oxoglutarate dehydrogenase, E1 component, ev=0.0, 78% identity; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component: (0); PFAM: dehydrogenase, E1 component: (3e-31) Transketolase, central region: (4.2e-68). (986 aa) |
| | Dgeo_0159 | 3-mercaptopyruvate sulfurtransferase; PFAM: Rhodanese-like: (4e-09); KEGG: dra:DR2531 thiosulfate sulfurtransferase, ev=1e-125, 76% identity. (292 aa) |
| | ubiX | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (198 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (412 aa) |
| | mgsA | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (137 aa) |
| | Dgeo_0242 | ROK domain protein; PFAM: ROK: (1.7e-54); KEGG: dra:DR2296 glucokinase, ev=1e-128, 76% identity. (320 aa) |
| | Dgeo_0348 | KEGG: syf:Synpcc7942_2420 serine O-acetyltransferase, ev=7e-29, 45% identity. (171 aa) |
| | Dgeo_0353 | TIGRFAM: Dihydrolipoamide dehydrogenase: (1.1e-231); PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase: (3e-29) glucose-inhibited division protein A: (0.00016) fumarate reductase/succinate dehydrogenase flavoprotein-like: (0.0029) pyridine nucleotide-disulphide oxidoreductase dimerisation region: (6.2e-64) HI0933-like protein: (0.001); KEGG: dra:DR2526 lipoamide dehydrogenase E3 component, ev=0.0, 83% identity. (468 aa) |
| | Dgeo_0428 | PFAM: acyl-CoA dehydrogenase-like: (2.9e-63) Acyl-CoA dehydrogenase, type 2-like: (8.1e-27); KEGG: dra:DR0922 acyl-CoA dehydrogenase, ev=0.0, 88% identity. (380 aa) |
| | pdxH | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (218 aa) |
| | Dgeo_0452 | KEGG: dra:DR1456 ribose-phosphate pyrophosphokinase, ev=1e-156, 88% identity; TIGRFAM: ribose-phosphate pyrophosphokinase: (1.3e-120); PFAM: phosphoribosyltransferase: (2e-23). (355 aa) |
| | Dgeo_0454 | PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase: (1.2e-06); KEGG: dra:DR1764 hypothetical protein, ev=3e-99, 65% identity. (282 aa) |
| | Dgeo_0455 | PFAM: Rieske [2Fe-2S] region: (2.4e-22); KEGG: dra:DR1950 ferredoxin, putative, ev=3e-36, 72% identity. (108 aa) |
| | Dgeo_0466 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (445 aa) |
| | Dgeo_0467 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (177 aa) |
| | Dgeo_0494 | PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal: (4.3e-121) Glu/Leu/Phe/Val dehydrogenase, dimerisation region: (2.9e-74); KEGG: bte:BTH_I1224 glutamate dehydrogenase, ev=0.0, 69% identity; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (440 aa) |
| | Dgeo_0495 | PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal: (2.3e-50) Glu/Leu/Phe/Val dehydrogenase, dimerisation region: (2e-55); KEGG: tth:TTC1212 glutamate dehydrogenase, ev=1e-100, 48% identity; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (414 aa) |
| | acyP | PFAM: acylphosphatase: (7e-08); KEGG: dra:DR0929 acylphosphatase, putative, ev=2e-32, 77% identity. (87 aa) |
| | folD1 | Methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (288 aa) |
| | Dgeo_0575 | ROK domain protein; PFAM: ROK: (5.5e-08); KEGG: dra:DR0823 ROK family protein, ev=1e-104, 77% identity. (270 aa) |
| | Dgeo_0610 | PFAM: homoserine dehydrogenase: (1.5e-46) homoserine dehydrogenase, NAD-binding: (2.2e-15); KEGG: dra:DR1278 homoserine dehydrogenase, ev=1e-138, 76% identity. (320 aa) |
| | Dgeo_0617 | 3-hydroxyacyl-CoA dehydrogenase, NAD-binding protein; PFAM: Enoyl-CoA hydratase/isomerase: (8.7e-07) 3-hydroxyacyl-CoA dehydrogenase-like: (3.5e-10) 3-hydroxyacyl-CoA dehydrogenase, NAD-binding: (9.8e-57); KEGG: dra:DR2477 3-hydroxyacyl-CoA dehydrogenase, ev=0.0, 81% identity. (782 aa) |
| | Dgeo_0618 | Acetyl-CoA C-acyltransferase; PFAM: Thiolase: (4.5e-110) 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal: (0.0025); KEGG: dra:DR2480 acetyl-CoA acetyltransferase, ev=0.0, 87% identity; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa) |
| | Dgeo_0621 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (793 aa) |
| | Dgeo_0623 | Glycolate oxidase, Fe-S subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding: (4.1e-05) protein of unknown function DUF224, cysteine-rich region: (2.3e-20); KEGG: dra:DR1730 glycolate oxidase, iron-sulfur subunit, ev=0.0, 85% identity. (425 aa) |
| | Dgeo_0624 | Glycolate oxidase subunit, GlcD; PFAM: FAD linked oxidase-like: (2.4e-89); KEGG: dra:DR1731 glycolate oxidase subunit GlcD, ev=0.0, 80% identity. (482 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (831 aa) |
| | folD2 | Methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (289 aa) |
| | Dgeo_0710 | TIGRFAM: D-3-phosphoglycerate dehydrogenase: (4.8e-212); PFAM: amino acid-binding ACT: (6.3e-07) D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region: (9.6e-40) D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding: (8.5e-87); KEGG: dra:DR1291 D-3-phosphoglycerate dehydrogenase, ev=0.0, 86% identity. (542 aa) |
| | Dgeo_0717 | PFAM: Carboxymuconolactone decarboxylase: (8.3e-26); KEGG: dra:DR0973 gamma-carboxymuconolactone decarboxylase, ev=3e-51, 83% identity. (147 aa) |
| | Dgeo_0754 | 3-hydroxyacyl-CoA dehydrogenase; PFAM: Enoyl-CoA hydratase/isomerase: (2.2e-60) 3-hydroxyacyl-CoA dehydrogenase-like: (0.00023) 3-hydroxyacyl-CoA dehydrogenase, NAD-binding: (5.1e-93); KEGG: dra:DR1487 enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxybutyryl-CoA epimerase, ev=0.0, 80% identity. (695 aa) |
| | Dgeo_0755 | PFAM: Thiolase: (8.4e-92); KEGG: dra:DR1428 acetyl-CoA acetyltransferase, ev=0.0, 85% identity; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (385 aa) |
| | Dgeo_0862 | KEGG: dra:DR1189 methylmalonyl-CoA mutase, alpha subunit, chain A, ev=0.0, 91% identity; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain: (8.1e-224); PFAM: methylmalonyl-CoA mutase: (1.8e-235). (548 aa) |
| | Dgeo_0882 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase: (2.8e-187); KEGG: dra:DR2160 delta-aminolevulinic acid dehydratase, ev=1e-137, 75% identity; Belongs to the ALAD family. (327 aa) |
| | Dgeo_0886 | KEGG: dra:DR0951 succinate dehydrogenase iron-sulfur protein, ev=1e-117, 79% identity; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein: (6e-82); PFAM: ferredoxin: (0.037). (253 aa) |
| | Dgeo_0887 | KEGG: dra:DR0952 succinate dehydrogenase flavoprotein subunit, ev=0.0, 85% identity; TIGRFAM: succinate dehydrogenase, flavoprotein subunit: (0) succinate dehydrogenase or fumarate reductase, flavoprotein subunit: (0); PFAM: fumarate reductase/succinate dehydrogenase flavoprotein-like: (4e-145) FAD dependent oxidoreductase: (1.1e-05) FAD-dependent pyridine nucleotide-disulphide oxidoreductase: (0.00053). (583 aa) |
| | Dgeo_0888 | PFAM: succinate dehydrogenase, cytochrome b subunit: (1e-05); KEGG: dra:DR0953 succinate dehydrogenase hydrophobic membrane anchor protein, ev=2e-57, 82% identity. (125 aa) |
| | Dgeo_0889 | PFAM: succinate dehydrogenase, cytochrome b subunit: (3.2e-06); KEGG: dra:DR0954 succinate dehydrogenase cytochrome b-556 subunit, ev=8e-48, 76% identity. (118 aa) |
| | argD | PFAM: aminotransferase class-III: (6.4e-141); KEGG: dra:DRA0029 4-aminobutyrate aminotransferase, ev=0.0, 82% identity; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (458 aa) |
| | gluQ | glutamyl-tRNA synthetase, class Ic; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (303 aa) |
| | sucC | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (385 aa) |
| | sucD | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (303 aa) |
| | tal | Transaldolase, putative; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (246 aa) |
| | Dgeo_1114 | Serine--pyruvate transaminase; PFAM: aminotransferase, class V: (2.4e-14); KEGG: dra:DR1350 putative aminotransferase, ev=1e-170, 78% identity. (384 aa) |
| | Dgeo_1120 | PFAM: aldehyde dehydrogenase: (3.5e-170); KEGG: dra:DRA0343 succinic-semialdehyde dehydrogenase, putative, ev=0.0, 70% identity. (485 aa) |
| | Dgeo_1127 | KEGG: dra:DR1365 aspartate kinase, ev=0.0, 82% identity; TIGRFAM: aspartate kinase: (1.1e-148) aspartate kinase, monofunctional class: (1.6e-127); PFAM: aspartate/glutamate/uridylate kinase: (5.7e-67) amino acid-binding ACT: (1.9e-12); Belongs to the aspartokinase family. (470 aa) |
| | Dgeo_1133 | KEGG: dra:DR1343 glyceraldehyde 3-phosphate dehydrogenase, ev=1e-158, 83% identity; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I: (1.8e-183); PFAM: glyceraldehyde 3-phosphate dehydrogenase: (1.3e-98); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (331 aa) |
| | pgk | PFAM: phosphoglycerate kinase: (1.8e-194); KEGG: dra:DR1342 phosphoglycerate kinase, ev=1e-172, 77% identity; Belongs to the phosphoglycerate kinase family. (389 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (244 aa) |
| | Dgeo_1149 | Glucose dehydrogenase, Gcd and cytochrome c-like domain; PFAM: Pyrrolo-quinoline quinone: (1.4e-06) cytochrome c, class I: (0.0084); KEGG: bja:blr6207 probable quinoprotein ethanol dehydrogenase precursor, ev=8e-85, 37% identity. (678 aa) |
| | leuD-2 | Lysine biosynthesis protein, homoaconitate hydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (169 aa) |
| | leuC-2 | Lysine biosynthesis protein, homoaconitate hydratase family protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (419 aa) |
| | Dgeo_1166 | PFAM: isocitrate/isopropylmalate dehydrogenase: (1.9e-155); KEGG: dra:DR1540 isocitrate dehydrogenase, ev=0.0, 85% identity. (420 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (529 aa) |
| | Dgeo_1203 | PFAM: glutamine synthetase, catalytic region: (1.2e-16); KEGG: dra:DR2033 glutamine synthase, ev=0.0, 77% identity. (718 aa) |
| | Dgeo_1204 | KEGG: dra:DR0451 glutamine synthase, ev=0.0, 80% identity; TIGRFAM: glutamine synthetase, type I: (4.1e-212); PFAM: glutamine synthetase, catalytic region: (4.7e-146) glutamine synthetase, beta-Grasp: (3.9e-07). (452 aa) |
| | Dgeo_1221 | PFAM: acyl-CoA dehydrogenase-like: (1.1e-37) Acyl-CoA dehydrogenase, type 2-like: (6.6e-05); KEGG: dra:DR0551 glutaryl-CoA dehydrogenase, putative, ev=1e-173, 73% identity. (466 aa) |
| | Dgeo_1257 | TIGRFAM: Homocitrate synthase, fungi and archaea: (7.9e-185); PFAM: pyruvate carboxyltransferase: (1.9e-70); KEGG: dra:DR1238 homocitrate synthase, ev=0.0, 90% identity; Belongs to the alpha-IPM synthase/homocitrate synthase family. (389 aa) |
| | rpiA | Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (228 aa) |
| | Dgeo_1287 | TIGRFAM: isocitrate lyase: (6.6e-185); PFAM: isocitrate lyase and phosphorylmutase: (1.6e-236); KEGG: dra:DR0828 isocitrate lyase, ev=0.0, 89% identity. (443 aa) |
| | Dgeo_1290 | PFAM: phosphoesterase, RecJ-like: (2.2e-16) phosphoesterase, DHHA1: (3.4e-08); KEGG: dra:DR0826 hypothetical protein, ev=1e-139, 75% identity. (335 aa) |
| | pgi | PFAM: phosphoglucose isomerase (PGI): (7.5e-272); KEGG: dra:DR1742 glucose-6-phosphate isomerase, ev=0.0, 77% identity. (649 aa) |
| | comB | PFAM: 2-phosphosulfolactate phosphatase: (1.9e-79); KEGG: dra:DR1400 putative 2-phosphosulfolactate phosphatase, ev=6e-81, 67% identity; Belongs to the ComB family. (241 aa) |
| | Dgeo_1319 | PFAM: ribulose-phosphate 3-epimerase: (4.4e-103); KEGG: dra:DR1401 ribulose-phosphate 3-epimerase, ev=7e-95, 77% identity; Belongs to the ribulose-phosphate 3-epimerase family. (229 aa) |
| | Dgeo_1320 | KEGG: dra:DR1084 methylmalonyl-CoA mutase, beta subunit, ev=0.0, 85% identity; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain: (5.2e-273) methylmalonyl-CoA mutase C-terminal domain: (6.1e-60); PFAM: methylmalonyl-CoA mutase: (0) cobalamin B12-binding: (7.7e-28). (722 aa) |
| | Dgeo_1333 | PFAM: Amidase: (1.7e-97); KEGG: dra:DR1625 amidase, putative, ev=1e-176, 68% identity. (468 aa) |
| | Dgeo_1407 | PFAM: nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin-like: (1.1e-18) nitrite and sulphite reductase 4Fe-4S region: (2e-13); KEGG: dra:DRA0013 ferredoxin-nitrite reductase, ev=0.0, 78% identity. (521 aa) |
| | cysC | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. (181 aa) |
| | Dgeo_1409 | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (239 aa) |
| | sat | KEGG: dra:DRA0016 sulfate adenylyltransferase, ev=0.0, 82% identity; TIGRFAM: sulfate adenylyltransferase: (2.7e-165); PFAM: ATP-sulfurylase: (1.4e-156); Belongs to the sulfate adenylyltransferase family. (389 aa) |
| | Dgeo_1441 | PFAM: Thiolase: (6.2e-154); KEGG: dra:DR1072 acetyl-CoA acetyltransferase, ev=0.0, 82% identity; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa) |
| | Dgeo_1444 | PFAM: 3-hydroxyacyl-CoA dehydrogenase-like: (3e-55) 3-hydroxyacyl-CoA dehydrogenase, NAD-binding: (3.6e-93); KEGG: dra:DR1068 3-hydroxybutyryl-CoA dehydrogenase, ev=1e-133, 85% identity. (278 aa) |
| | Dgeo_1451 | Threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase: (3.9e-148) aminotransferase, class I and II: (9.3e-06); KEGG: dra:DR1313 L-allo-threonine aldolase, ev=1e-150, 80% identity. (345 aa) |
| | Dgeo_1458 | PFAM: isocitrate/isopropylmalate dehydrogenase: (4.2e-127); KEGG: dra:DR1674 isocitrate dehydrogenase, ev=1e-164, 86% identity. (333 aa) |
| | Dgeo_1526 | KEGG: dra:DR0757 citrate synthase, ev=0.0, 84% identity; TIGRFAM: 2-methylcitrate synthase/citrate synthase II: (1.1e-247); PFAM: Citrate synthase: (4.7e-142); Belongs to the citrate synthase family. (390 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (480 aa) |
| | Dgeo_1541 | methylmalonyl-CoA mutase, alpha subunit; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain: (5.3e-45); PFAM: cobalamin B12-binding: (1.7e-41); KEGG: dra:DR2032 methylmalonyl-CoA mutase, alpha subunit, chain B, ev=1e-60, 85% identity. (151 aa) |
| | pdhA | 2-oxoisovalerate dehydrogenase, OdbA; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (361 aa) |
| | Dgeo_1562 | 2-oxoisovalerate dehydrogenase, OdbB; PFAM: Transketolase, central region: (3.3e-66) Transketolase-like: (6.9e-47); KEGG: ttj:TTHA0938 pyruvate dehydrogenase E1 component, beta subunit, ev=1e-125, 67% identity. (334 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (336 aa) |
| | Dgeo_1657 | TIGRFAM: cysteine synthases: (8.1e-200) cysteine synthase A: (4.6e-208); PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit: (2.9e-117); KEGG: dra:DR0789 O-acetylserine (thiol)-lyase, ev=1e-153, 83% identity; Belongs to the cysteine synthase/cystathionine beta- synthase family. (322 aa) |
| | Dgeo_1682 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (906 aa) |
| | Dgeo_1685 | PFAM: aldo/keto reductase: (1.3e-42); KEGG: dra:DR1890 oxidoreductase, putative, ev=1e-138, 83% identity. (300 aa) |
| | Dgeo_1750 | PFAM: AMP-dependent synthetase and ligase: (5.5e-117); KEGG: dra:DR0460 acetyl-CoA synthase, ev=0.0, 78% identity. (636 aa) |
| | acsA | Acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (655 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase, USG-1 related protein; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (339 aa) |
| | Dgeo_1790 | PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase: (2.8e-11); KEGG: dra:DR2022 hypothetical protein, ev=3e-59, 77% identity. (158 aa) |
| | Dgeo_1797 | PFAM: Enoyl-CoA hydratase/isomerase: (5.2e-38); KEGG: dra:DR2510 enoyl-CoA hydratase, putative, ev=1e-115, 81% identity. (261 aa) |
| | Dgeo_1875 | TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific: (0); PFAM: phosphoglucomutase/phosphomannomutase C terminal: (2.9e-12) phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I: (1.1e-35) phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II: (2.5e-17) phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III: (1.9e-32); KEGG: pca:Pcar_1989 phosphoglucomutase, alpha-D-glucose phosphate-specific, ev=0.0, 61% identity. (547 aa) |
| | Dgeo_1876 | TIGRFAM: fructose-1,6-bisphosphatase, class II: (2.5e-108); PFAM: GlpX: (5.6e-158); KEGG: ttj:TTHA1446 fructose-1,6-bisphosphatase, class II, ev=1e-127, 71% identity. (334 aa) |
| | Dgeo_1883 | PFAM: Thiolase: (7e-144); KEGG: dra:DR1960 acetyl-CoA acetyltransferase, ev=1e-163, 73% identity; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa) |
| | Dgeo_1886 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (594 aa) |
| | Dgeo_1887 | 2-oxo-acid dehydrogenase E1 component, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (902 aa) |
| | Dgeo_1913 | TIGRFAM: Phenylacetic acid degradation protein paaN: (0); PFAM: aldehyde dehydrogenase: (1.2e-18) MaoC-like dehydratase: (8.9e-32); KEGG: dra:DR2381 aldehyde dehydrogenase, ev=0.0, 82% identity. (695 aa) |
| | Dgeo_1915 | TIGRFAM: Phenylacetate-CoA oxygenase, PaaJ subunit: (3.9e-97); PFAM: protein of unknown function DUF59: (2.3e-33); KEGG: dra:DR2383 phenylacetic acid degradation protein PaaD, ev=3e-68, 77% identity. (171 aa) |
| | Dgeo_1916 | TIGRFAM: Phenylacetate-CoA oxygenase, PaaI subunit: (3.2e-132); PFAM: phenylacetic acid catabolic: (5.3e-110); KEGG: dra:DR2384 phenylacetic acid degradation protein PaaC, ev=2e-98, 72% identity. (268 aa) |
| | Dgeo_1917 | Phenylacetate-CoA oxygenase, PaaB subunit; PFAM: phenylacetic acid degradation B: (8.2e-06); KEGG: dra:DR2385 phenylacetic acid degradation protein PaaB, putative, ev=2e-81, 75% identity. (192 aa) |
| | Dgeo_1918 | TIGRFAM: Phenylacetate-CoA oxygenase, PaaG subunit: (4e-237); PFAM: phenylacetic acid catabolic: (2.1e-189); KEGG: dra:DR2386 phenylacetic acid degradation protein PaaA, ev=1e-169, 87% identity. (320 aa) |
| | hemL | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase: (4.9e-217); PFAM: aminotransferase class-III: (3.9e-73); KEGG: dra:DR0555 glutamate-1-semialdehyde 2,1-aminomutase, ev=0.0, 74% identity. (457 aa) |
| | Dgeo_1973 | TIGRFAM: 6-phosphogluconate dehydrogenase related protein: (1.5e-133); PFAM: 6-phosphogluconate dehydrogenase-like: (3.9e-10) 6-phosphogluconate dehydrogenase, NAD-binding: (9.9e-51); KEGG: dra:DR1595 6-phosphogluconate dehydrogenase, ev=1e-159, 76% identity. (360 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (560 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (225 aa) |
| | Dgeo_2023 | PFAM: Aldose 1-epimerase: (1.2e-31); KEGG: dra:DR0747 aldose epimerase family protein, ev=1e-120, 70% identity. (298 aa) |
| | Dgeo_2069 | Succinyldiaminopimelate aminotransferase apoenzyme; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase: (0.00056) aminotransferase, class I and II: (1.4e-66); KEGG: dra:DR0671 aminotransferase, class I, ev=1e-134, 65% identity. (375 aa) |
| | Dgeo_2083 | Fructose-1,6-bisphosphate aldolase, class II; KEGG: dra:DR1589 fructose-bisphosphate aldolase, ev=1e-152, 88% identity; TIGRFAM: ketose-bisphosphate aldolases: (5.7e-100) fructose-1,6-bisphosphate aldolase, class II: (6.8e-209); PFAM: ketose-bisphosphate aldolase, class-II: (1.9e-127). (308 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (365 aa) |
| | Dgeo_2129 | Precorrin-2 dehydrogenase; TIGRFAM: siroheme synthase, N-terminal domain: (1.4e-19); KEGG: cvi:CV0813 uroporphyrin-III C-methyltransferase, ev=2e-23, 46% identity. (188 aa) |
| | Dgeo_2131 | TIGRFAM: uroporphyrin-III C-methyltransferase: (9e-132); PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase: (6.1e-80) Uroporphyrinogen III synthase HEM4: (1e-26); KEGG: dra:DRA0011 uroporphyrin-III synthase / uroporphyrin-III C-methyltransferase, ev=1e-147, 60% identity. (507 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (334 aa) |
| | Dgeo_2162 | PFAM: Enoyl-CoA hydratase/isomerase: (8.7e-23); KEGG: dra:DR0184 enoyl-CoA hydratase, putative, ev=1e-132, 84% identity; Belongs to the enoyl-CoA hydratase/isomerase family. (273 aa) |
| | Dgeo_2175 | TIGRFAM: PTS system, fructose-specific, IIB component: (8.1e-56) Phosphotransferase system, fructose IIC component: (2.9e-130); PFAM: phosphotransferase system, EIIC: (1.5e-23) phosphotransferase system PTS, fructose-specific IIB subunit: (2e-58); KEGG: dra:DRB0073 PTS system, fructose-specific IIBC component, ev=0.0, 79% identity; TC 4.A.2.1.1; TC 4.A.2.1.1. (607 aa) |
| | accA | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (306 aa) |
| | accD | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (284 aa) |
| | Dgeo_2206 | Thiosulfate sulfurtransferase; PFAM: Rhodanese-like: (2.5e-28); KEGG: dra:DR0217 thiosulfate sulfurtransferase, ev=1e-146, 83% identity. (286 aa) |
| | Dgeo_2228 | PFAM: Phosphoglycerate mutase: (1.1e-37); KEGG: dra:DR0602 phosphoglycerate mutase-related protein, ev=1e-70, 67% identity. (227 aa) |
| | apgM | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (408 aa) |
| | Dgeo_2245 | Citrate synthase; PFAM: regulatory protein, MerR: (5.2e-07) Citrate synthase: (3.6e-14); KEGG: mlo:mlr3843 citrate synthase II, ev=9e-72, 43% identity. (402 aa) |
| | Dgeo_2246 | HMGL-like domain protein; PFAM: pyruvate carboxyltransferase: (2.7e-11); KEGG: cac:CAC0970 isopropylmalate synthase, ev=4e-71, 38% identity. (436 aa) |
| | Dgeo_2252 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (345 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (317 aa) |
| | Dgeo_2283 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (667 aa) |
| | Dgeo_2296 | PFAM: Alcohol dehydrogenase, zinc-binding: (2.3e-28) Alcohol dehydrogenase GroES-like: (5.3e-36); KEGG: pst:PSPTO2676 glutathione-independent formaldehyde dehydrogenase, ev=1e-161, 70% identity. (379 aa) |
| | Dgeo_2323 | TIGRFAM: Dihydrolipoamide dehydrogenase: (3.5e-224); PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase: (4.7e-29) pyridine nucleotide-disulphide oxidoreductase dimerisation region: (2.7e-62); KEGG: dra:DR2370 pyruvate dehydrogenase complex, dihydrolipoamide dehydrogenase E3 component, putative, ev=0.0, 82% identity. (467 aa) |
| | fumC | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (479 aa) |
| | Dgeo_2341 | Dihydrolipoamide acyltransferase, (E2) component; PFAM: biotin/lipoyl attachment: (4e-24) catalytic domain of components of various dehydrogenase complexes: (6.2e-128) E3 binding: (4.3e-18); KEGG: dra:DR0032 pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase), ev=0.0, 69% identity. (516 aa) |
