(92 nodes) Cytoskeletal protein binding, and Microtubule associated complex network (Pseudocercospora eumusae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AC578_10637	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (132 aa)
	AC578_3847	WD_REPEATS_REGION domain-containing protein. (438 aa)
	AC578_996	Uncharacterized protein. (327 aa)
	AC578_9942	Uncharacterized protein. (643 aa)
	AC578_9338	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (192 aa)
	AC578_4505	Uncharacterized protein; Belongs to the actin family. (379 aa)
	AC578_11169	Protein kinase domain-containing protein. (468 aa)
	AC578_4050	Uncharacterized protein. (868 aa)
	AC578_1500	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1208 aa)
	AC578_5848	Uncharacterized protein. (201 aa)
	AC578_5284	Adenylyl cyclase-associated protein; Belongs to the CAP family. (552 aa)
	AC578_2639	Uncharacterized protein. (787 aa)
	AC578_9375	ADF-H domain-containing protein. (170 aa)
	AC578_3076	Uncharacterized protein. (644 aa)
	AC578_3219	Uncharacterized protein. (1082 aa)
	AC578_5829	CAP-Gly domain-containing protein. (1319 aa)
	AC578_6314	Uncharacterized protein; Belongs to the actin family. (520 aa)
	AC578_10445	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (730 aa)
	AC578_9426	Csm1 domain-containing protein. (504 aa)
	AC578_7393	Uncharacterized protein. (135 aa)
	AC578_859	DUF2013 domain-containing protein. (515 aa)
	AC578_9622	Uncharacterized protein. (665 aa)
	AC578_10736	Uncharacterized protein. (129 aa)
	AC578_5756	Uncharacterized protein. (209 aa)
	AC578_8747	Uncharacterized protein. (202 aa)
	AC578_4653	Structural maintenance of chromosomes protein. (1491 aa)
	AC578_8051	Uncharacterized protein. (752 aa)
	AC578_10079	Uncharacterized protein. (170 aa)
	AC578_1266	Uncharacterized protein. (89 aa)
	AC578_9035	NUDE_C domain-containing protein. (611 aa)
	AC578_2038	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1072 aa)
	AC578_4992	Structural maintenance of chromosomes protein. (1180 aa)
	AC578_6885	ECM11 domain-containing protein. (569 aa)
	AC578_8999	Uncharacterized protein. (232 aa)
	AC578_9849	Uncharacterized protein. (116 aa)
	AC578_4493	Uncharacterized protein. (485 aa)
	AC578_5810	Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (814 aa)
	AC578_3287	Uncharacterized protein. (340 aa)
	AC578_6457	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1080 aa)
	AC578_3347	Uncharacterized protein. (559 aa)
	AC578_4065	Protein kinase domain-containing protein. (683 aa)
	AC578_3172	Cupin type-1 domain-containing protein. (142 aa)
	AC578_8269	Protein kinase domain-containing protein. (903 aa)
	AC578_8230	Robl_LC7 domain-containing protein. (138 aa)
	AC578_2948	Uncharacterized protein. (298 aa)
	AC578_967	WD_REPEATS_REGION domain-containing protein. (616 aa)
	AC578_5707	Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. (100 aa)
	AC578_8197	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1107 aa)
	AC578_610	Protein kinase domain-containing protein. (905 aa)
	AC578_2702	Uncharacterized protein. (207 aa)
	AC578_4520	Uncharacterized protein. (604 aa)
	AC578_4540	Uncharacterized protein. (262 aa)
	AC578_4547	Uncharacterized protein. (605 aa)
	AC578_2808	Uncharacterized protein. (514 aa)
	AC578_185	Uncharacterized protein. (672 aa)
	AC578_7849	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (772 aa)
	AC578_5446	Uncharacterized protein; Belongs to the actin family. (849 aa)
	AC578_1848	Uncharacterized protein. (207 aa)
	AC578_4806	Uncharacterized protein. (524 aa)
	AC578_7689	Uncharacterized protein. (428 aa)
	AC578_4798	DHR10 domain-containing protein. (467 aa)
	AC578_4802	Uncharacterized protein; Belongs to the actin family. (441 aa)
	AC578_4737	Uncharacterized protein. (5132 aa)
	AC578_1627	Cnd3 domain-containing protein. (1067 aa)
	AC578_8926	Uncharacterized protein. (829 aa)
	AC578_9309	Uncharacterized protein. (2189 aa)
	AC578_9305	CUE domain-containing protein. (509 aa)
	AC578_9270	Uncharacterized protein. (736 aa)
	AC578_4907	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1217 aa)
	AC578_9285	Uncharacterized protein. (809 aa)
	AC578_101	Uncharacterized protein. (2753 aa)
	AC578_7903	WD_REPEATS_REGION domain-containing protein. (743 aa)
	AC578_8730	Uncharacterized protein. (403 aa)
	AC578_3620	Uncharacterized protein. (582 aa)
	AC578_8732	Uncharacterized protein. (507 aa)
	AC578_2103	SH3 domain-containing protein. (395 aa)
	AC578_8398	Ysc84 domain-containing protein. (631 aa)
	AC578_11020	Uncharacterized protein. (738 aa)
	AC578_3706	Uncharacterized protein. (651 aa)
	AC578_5587	Calponin-homology (CH) domain-containing protein. (691 aa)
	AC578_294	Uncharacterized protein. (198 aa)
	AC578_1331	Spc7 domain-containing protein. (1250 aa)
	AC578_6099	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)
	AC578_8547	Uncharacterized protein. (803 aa)
	AC578_8537	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
	AC578_7206	PH domain-containing protein. (1647 aa)
	AC578_2425	Uncharacterized protein. (609 aa)
	AC578_497	Uncharacterized protein. (880 aa)
	AC578_558	Uncharacterized protein. (189 aa)
	AC578_10206	CAP-Gly domain-containing protein. (741 aa)
	AC578_10237	Uncharacterized protein. (420 aa)
	AC578_10222	Uncharacterized protein. (1829 aa)

Your Current Organism:

Pseudocercospora eumusae

NCBI taxonomy Id: 321146
Other names: Mycosphaerella eumusae, Mycosphaerella eumusae Crous & Mour., 2002, P. eumusae, PREM 57315, Pseudocercospora eumusae Crous & Mour., 2002, Septoria eumusae, Septoria eumusae Carlier, M.-F. Zapater, Lapeyre, D.R. Jones & Mour., 2000

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AC578_10079	AC578_2425	A0A139H868	A0A139HXR2	Uncharacterized protein.	Uncharacterized protein.	0.407
AC578_10079	AC578_4540	A0A139H868	A0A139HGF8	Uncharacterized protein.	Uncharacterized protein.	0.656
AC578_10079	AC578_4798	A0A139H868	A0A139HLD1	Uncharacterized protein.	DHR10 domain-containing protein.	0.644
AC578_10079	AC578_8051	A0A139H868	A0A139H7J8	Uncharacterized protein.	Uncharacterized protein.	0.621
AC578_101	AC578_10637	A0A139HP34	A0A139GTM0	Uncharacterized protein.	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	0.691
AC578_101	AC578_11020	A0A139HP34	A0A139HSJ7	Uncharacterized protein.	Uncharacterized protein.	0.464
AC578_101	AC578_2702	A0A139HP34	A0A139HFU8	Uncharacterized protein.	Uncharacterized protein.	0.464
AC578_101	AC578_4505	A0A139HP34	A0A139GWE8	Uncharacterized protein.	Uncharacterized protein; Belongs to the actin family.	0.464
AC578_101	AC578_4802	A0A139HP34	A0A139HLH9	Uncharacterized protein.	Uncharacterized protein; Belongs to the actin family.	0.455
AC578_101	AC578_5446	A0A139HP34	A0A139HK20	Uncharacterized protein.	Uncharacterized protein; Belongs to the actin family.	0.474
AC578_101	AC578_6314	A0A139HP34	A0A139H263	Uncharacterized protein.	Uncharacterized protein; Belongs to the actin family.	0.464
AC578_101	AC578_9309	A0A139HP34	A0A139HN89	Uncharacterized protein.	Uncharacterized protein.	0.464
AC578_10206	AC578_10222	A0A139HYY4	A0A139HZ71	CAP-Gly domain-containing protein.	Uncharacterized protein.	0.423
AC578_10206	AC578_10237	A0A139HYY4	A0A139HYY5	CAP-Gly domain-containing protein.	Uncharacterized protein.	0.800
AC578_10206	AC578_10445	A0A139HYY4	A0A139H2D3	CAP-Gly domain-containing protein.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.418
AC578_10206	AC578_1500	A0A139HYY4	A0A139GXI3	CAP-Gly domain-containing protein.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.488
AC578_10206	AC578_2038	A0A139HYY4	A0A139H8Z3	CAP-Gly domain-containing protein.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.565
AC578_10206	AC578_3347	A0A139HYY4	A0A139HD64	CAP-Gly domain-containing protein.	Uncharacterized protein.	0.849
AC578_10206	AC578_4050	A0A139HYY4	A0A139GX81	CAP-Gly domain-containing protein.	Uncharacterized protein.	0.836
AC578_10206	AC578_4505	A0A139HYY4	A0A139GWE8	CAP-Gly domain-containing protein.	Uncharacterized protein; Belongs to the actin family.	0.594

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