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| | ureC | Urease, alpha subunit; Identified by similarity to SP:P73061; match to protein family HMM PF00449; match to protein family HMM PF01979; match to protein family HMM TIGR01792; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. (572 aa) |
| | nirA | Ferredoxin-nitrite reductase; Identified by match to protein family HMM PF01077; match to protein family HMM PF03460; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (515 aa) |
| | narB | Nitrate reductase; Identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. (711 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (306 aa) |
| | folD | FolD bifunctional protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (293 aa) |
| | CYB_0092 | Pyridoxamine 5'-phosphate oxidase family protein; Identified by similarity to SP:Q51521; match to protein family HMM PF01243. (205 aa) |
| | sir | Sulfite reductase, ferredoxin dependent; Identified by similarity to SP:P30008; match to protein family HMM PF01077; match to protein family HMM PF03460; match to protein family HMM TIGR02042; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (593 aa) |
| | CYB_0217 | Aspartate kinase; Identified by similarity to SP:P41403; match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00657. (616 aa) |
| | ubiX | Decarboxylase, polyprenyl P-hydroxybenzoate/phenylacrylic acid family; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (215 aa) |
| | CYB_0241 | Aldehyde-alcohol dehydrogenase; Identified by similarity to SP:P17547; match to protein family HMM PF00171; match to protein family HMM PF00465; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (876 aa) |
| | pflB | Formate acetyltransferase; Identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255. (768 aa) |
| | comB | 2-phosphosulfolactate phosphatase; Identified by match to protein family HMM PF04029; match to protein family HMM TIGR00298; Belongs to the ComB family. (242 aa) |
| | pdhA | Dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (333 aa) |
| | fba | Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (359 aa) |
| | nifH | Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein. (292 aa) |
| | nifD | Nitrogenase molybdenum-iron protein alpha chain; Identified by similarity to SP:Q00239; match to protein family HMM PF00148; match to protein family HMM TIGR01282; match to protein family HMM TIGR01862. (487 aa) |
| | nifK | Nitrogenase molybdenum-iron protein beta chain; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation; Belongs to the NifD/NifK/NifE/NifN family. (511 aa) |
| | accB | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (157 aa) |
| | cysH | Phosophoadenylyl-sulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (248 aa) |
| | CYB_0441 | Identified by match to protein family HMM PF00485. (313 aa) |
| | cysQ | 3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (275 aa) |
| | CYB_0526 | Aspartate ammonia-lyase, putative; Identified by match to protein family HMM PF00206. (461 aa) |
| | CYB_0540 | Putative low specificity L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (346 aa) |
| | cobA/hemD | uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase; Identified by match to protein family HMM PF00590; match to protein family HMM PF02602; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family. (500 aa) |
| | acyP | Acylphosphatase; Identified by match to protein family HMM PF00708. (94 aa) |
| | lpdA | Dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF01266; match to protein family HMM PF02852; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01350. (460 aa) |
| | CYB_0796 | Identified by match to protein family HMM PF00857. (224 aa) |
| | CYB_0846 | Conserved domain protein. (172 aa) |
| | CYB_0923 | Identified by match to protein family HMM PF02219; Belongs to the methylenetetrahydrofolate reductase family. (305 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (286 aa) |
| | glk | Glucokinase; Identified by match to protein family HMM PF02685; match to protein family HMM TIGR00749; Belongs to the bacterial glucokinase family. (347 aa) |
| | hemL | Glutamate-1-semialdehyde-2,1-aminomutase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00713; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. (436 aa) |
| | CYB_1020 | Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family. (447 aa) |
| | cobA | uroporphyrin-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family. (260 aa) |
| | sat | Sulfate adenylyltransferase; Identified by match to protein family HMM PF01747; match to protein family HMM TIGR00339; Belongs to the sulfate adenylyltransferase family. (396 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 1 subfamily. (392 aa) |
| | ppsA | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (821 aa) |
| | CYB_1116 | 2-oxo acid dehydrogenase, acyltransferase, putative; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817. (424 aa) |
| | tkt | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (666 aa) |
| | CYB_1145 | D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase family protein; Identified by match to protein family HMM PF03894. (791 aa) |
| | gltS | Ferredoxin-dependent glutamate synthase; Identified by similarity to SP:P55038; match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. (1535 aa) |
| | CYB_1271 | Oxidoreductase, molybdopterin-binding subunit; Identified by match to protein family HMM PF00941. (268 aa) |
| | CYB_1348 | Succinate/fumarate oxidoreductase, putative; Identified by similarity to GB:CAA06782.1; match to protein family HMM PF02754. (297 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (285 aa) |
| | serA | D-3-phosphoglycerate dehydrogenase; Identified by match to protein family HMM PF00389; match to protein family HMM PF01842; match to protein family HMM PF02826; match to protein family HMM TIGR01327; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (526 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (403 aa) |
| | accC | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (451 aa) |
| | cysC | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. (175 aa) |
| | argD | Acetylornithine transaminase; Identified by similarity to SP:P54752; match to protein family HMM PF00202; match to protein family HMM TIGR00707; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (421 aa) |
| | hom | Homoserine dehydrogenase; Identified by similarity to SP:P08499; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447. (436 aa) |
| | gap-1 | Glyceraldehyde-3-phosphate dehydrogenase, type I; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (338 aa) |
| | CYB_1488 | Identified by match to protein family HMM PF01522. (290 aa) |
| | pyk | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF00391; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. (619 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (335 aa) |
| | acnB | Aconitate hydratase 2; Identified by match to protein family HMM PF00330; match to protein family HMM PF06434; match to protein family HMM TIGR00117; Belongs to the aconitase/IPM isomerase family. (874 aa) |
| | CYB_1607 | Glycerate kinase; Identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045; Belongs to the glycerate kinase type-1 family. (379 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (459 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (332 aa) |
| | CYB_1678 | Identified by match to protein family HMM PF00180. (356 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (479 aa) |
| | pgk | Phosphoglycerate kinase; Identified by match to protein family HMM PF00162; Belongs to the phosphoglycerate kinase family. (412 aa) |
| | gap-2 | Glyceraldehyde-3-phosphate dehydrogenase, type I; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (339 aa) |
| | CYB_1765 | Dehydrogenase, E1 component, beta subunit, putative; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (326 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (310 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (978 aa) |
| | CYB_1893 | Identified by match to protein family HMM PF00171. (461 aa) |
| | eda | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Identified by match to protein family HMM PF01081; match to protein family HMM TIGR01182. (237 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (308 aa) |
| | CYB_1908 | 2-methylcitrate synthase/citrate synthase II; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01800; Belongs to the citrate synthase family. (378 aa) |
| | cysK | Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; Belongs to the cysteine synthase/cystathionine beta- synthase family. (318 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (517 aa) |
| | fbp | Fructose-1,6-bisphosphatase; Identified by match to protein family HMM PF00316. (332 aa) |
| | rpiA | Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (238 aa) |
| | rpe | Ribulose-phosphate 3-epimerase; Identified by match to protein family HMM PF00834; match to protein family HMM TIGR01163; Belongs to the ribulose-phosphate 3-epimerase family. (236 aa) |
| | CYB_2127 | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Identified by match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910; match to protein family HMM PF07992; match to protein family HMM TIGR01812. (571 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa) |
| | ldh | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (306 aa) |
| | CYB_2175 | Glycolate oxidase, iron-sulfur subunit, putative; Identified by match to protein family HMM PF00037; match to protein family HMM PF02754. (436 aa) |
| | pfkA | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (370 aa) |
| | glpX | Fructose-1,6-bisphosphatase, class II; Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6- phosphate and sedoheptulose 7-phosphate, respectively; Belongs to the FBPase class 2 family. (347 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (431 aa) |
| | thrC-1 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (352 aa) |
| | CYB_2304 | Identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880. (543 aa) |
| | gap-3 | Glyceraldehyde-3-phosphate dehydrogenase, type I; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa) |
| | ureA | Urease, gamma subunit; Identified by similarity to SP:P73796; match to protein family HMM PF00547; match to protein family HMM TIGR00193; Belongs to the urease gamma subunit family. (100 aa) |
| | CYB_2384 | Pyruvate kinase barrel domain protein; Identified by match to protein family HMM PF00224; Belongs to the pyruvate kinase family. (476 aa) |
| | hemB | Delta-aminolevulinic acid dehydratase; Identified by match to protein family HMM PF00490; Belongs to the ALAD family. (328 aa) |
| | gnd | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (472 aa) |
| | CYB_2507 | Succinate dehydrogenase/fumarate reductase, iron-sulfur protein; Identified by match to protein family HMM TIGR00384. (343 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa) |
| | cbbS | Ribulose bisphosphate carboxylase, small subunit; Identified by match to protein family HMM PF00101. (110 aa) |
| | cbbL | Ribulose bisphosphate carboxylase, large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site. (474 aa) |
| | CYB_2659 | Amidohydrolase, AtzE family; Identified by match to protein family HMM PF01425; match to protein family HMM TIGR02715. (466 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (314 aa) |
| | gpmI | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (530 aa) |
| | CYB_2695 | Identified by match to protein family HMM PF01565. (384 aa) |
| | rhdA | Thiosulfate sulfurtransferase; Identified by similarity to SP:P52197; match to protein family HMM PF00581. (275 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (325 aa) |
| | glnA-2 | Glutamine synthetase, type I; Identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653. (474 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (427 aa) |
| | thrC-2 | Threonine synthase; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR00260. (446 aa) |
| | glcD | Glycolate oxidase, subunit GlcD; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913; match to protein family HMM TIGR00387. (501 aa) |
| | cysE | Serine O-acetyltransferase; Identified by similarity to SP:Q06750; match to protein family HMM PF00132; match to protein family HMM TIGR01172. (259 aa) |
| | prk | Phosphoribulokinase; Identified by match to protein family HMM PF00485. (335 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (243 aa) |
| | pgi | Glucose-6-phosphate isomerase; Identified by match to protein family HMM PF00342. (532 aa) |
