(54 nodes) Small-subunit processome, and Maturation of SSU-rRNA network (Parastagonospora nodorum)

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	SNOG_16443	Uncharacterized protein. (300 aa)
	SNOG_15842	S4 RNA-binding domain-containing protein. (189 aa)
	SNOG_15860	Uncharacterized protein. (2576 aa)
	SNOG_15750	U3 small nucleolar RNA-associated protein 22. (1206 aa)
	SNOG_15768	Uncharacterized protein. (791 aa)
	SNOG_15587	Utp12 domain-containing protein. (455 aa)
	SNOG_14489	Uncharacterized protein. (446 aa)
	NOP9	Nucleolar protein 9; RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity); Belongs to the NOP9 family. (726 aa)
	SNOG_14454	Uncharacterized protein. (985 aa)
	SNOG_14182	Helicase C-terminal domain-containing protein. (303 aa)
	SNOG_14181	Uncharacterized protein. (312 aa)
	SNOG_13093	Uncharacterized protein. (491 aa)
	SNOG_12497	NUC153 domain-containing protein. (705 aa)
	SNOG_12263	Uncharacterized protein. (274 aa)
	DBP8	ATP-dependent RNA helicase DBP8; ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites. Required for vegetative growth (By similarity); Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily. (508 aa)
	SNOG_11643	WD_REPEATS_REGION domain-containing protein. (544 aa)
	SNOG_11615	Uncharacterized protein. (410 aa)
	SNOG_11538	Uncharacterized protein. (830 aa)
	SNOG_11245	WD_REPEATS_REGION domain-containing protein. (889 aa)
	SNOG_10745	Uncharacterized protein. (491 aa)
	SNOG_10338	WD_REPEATS_REGION domain-containing protein. (489 aa)
	SNOG_10281	Uncharacterized protein. (1794 aa)
	SNOG_09025	Fcf2 domain-containing protein. (235 aa)
	DBP7	ATP-dependent RNA helicase DBP7; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs; Belongs to the DEAD box helicase family. DDX31/DBP7 subfamily. (831 aa)
	SNOG_08452	Uncharacterized protein. (1053 aa)
	SNOG_08340	WD_REPEATS_REGION domain-containing protein. (1046 aa)
	RRP3	ATP-dependent rRNA helicase RRP3; ATP-dependent rRNA helicase required for pre-ribosomal RNA processing. Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA. (546 aa)
	SNOG_07810	WD_REPEATS_REGION domain-containing protein. (553 aa)
	SNOG_07726	Uncharacterized protein. (1113 aa)
	SNOG_07244	Brix domain-containing protein. (295 aa)
	SNOG_07029	KH_8 domain-containing protein. (509 aa)
	SNOG_06761	Sas10 domain-containing protein. (661 aa)
	SNOG_05864	Bms1-type G domain-containing protein. (1172 aa)
	SNOG_05162	U3 small nucleolar ribonucleoprotein protein MPP10; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the MPP10 family. (733 aa)
	UTP25	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2. (687 aa)
	SNOG_04672	Uncharacterized protein. (890 aa)
	SNOG_04633	WD_REPEATS_REGION domain-containing protein. (937 aa)
	SNOG_04419	Uncharacterized protein. (407 aa)
	NAT10	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1068 aa)
	SNOG_04312	CBF domain-containing protein. (546 aa)
	SNOG_03884	PINc domain-containing protein. (282 aa)
	SNOG_03577	WD_REPEATS_REGION domain-containing protein. (773 aa)
	SNOG_03348	WD_REPEATS_REGION domain-containing protein. (594 aa)
	DBP3	ATP-dependent RNA helicase DBP3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity); Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily. (592 aa)
	SNOG_03110	Uncharacterized protein. (358 aa)
	DBP9	ATP-dependent RNA helicase DBP9; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs; Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily. (597 aa)
	SNOG_02949	RTC domain-containing protein. (397 aa)
	SNOG_02652	Uncharacterized protein. (597 aa)
	SNOG_02569	WD_REPEATS_REGION domain-containing protein. (437 aa)
	UTP10	U3 small nucleolar RNA-associated protein 10; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity). (1712 aa)
	SNOG_01577	BHLH domain-containing protein. (172 aa)
	RRP36	rRNA biogenesis protein RRP36; Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity). (331 aa)
	SNOG_01142	Uncharacterized protein. (1240 aa)
	SNOG_00764	Uncharacterized protein. (725 aa)

Your Current Organism:

Parastagonospora nodorum

NCBI taxonomy Id: 321614
Other names: P. nodorum SN15, Parastagonospora nodorum SN15, Phaeosphaeria nodorum SN15

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DBP3	DBP7	Q0UY62	Q0UHM7	ATP-dependent RNA helicase DBP3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity); Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.	ATP-dependent RNA helicase DBP7; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs; Belongs to the DEAD box helicase family. DDX31/DBP7 subfamily.	0.858
DBP3	DBP8	Q0UY62	Q0U8V9	ATP-dependent RNA helicase DBP3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity); Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.	ATP-dependent RNA helicase DBP8; ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites. Required for vegetative growth (By similarity); Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.	0.563
DBP3	DBP9	Q0UY62	Q0UZ59	ATP-dependent RNA helicase DBP3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity); Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.	ATP-dependent RNA helicase DBP9; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs; Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily.	0.882
DBP3	NAT10	Q0UY62	Q0UV38	ATP-dependent RNA helicase DBP3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity); Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	0.692
DBP3	NOP9	Q0UY62	Q0U154	ATP-dependent RNA helicase DBP3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity); Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.	Nucleolar protein 9; RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity); Belongs to the NOP9 family.	0.681
DBP3	RRP3	Q0UY62	Q0UK12	ATP-dependent RNA helicase DBP3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity); Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.	ATP-dependent rRNA helicase RRP3; ATP-dependent rRNA helicase required for pre-ribosomal RNA processing. Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA.	0.711
DBP3	RRP36	Q0UY62	Q0V389	ATP-dependent RNA helicase DBP3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity); Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.	rRNA biogenesis protein RRP36; Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).	0.422
DBP3	SNOG_00764	Q0UY62	Q0V5F0	ATP-dependent RNA helicase DBP3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity); Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.	Uncharacterized protein.	0.671
DBP3	SNOG_01142	Q0UY62	Q0V4C2	ATP-dependent RNA helicase DBP3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity); Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.	Uncharacterized protein.	0.647
DBP3	SNOG_01577	Q0UY62	Q0V337	ATP-dependent RNA helicase DBP3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity); Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.	BHLH domain-containing protein.	0.407
DBP3	SNOG_02569	Q0UY62	Q0V095	ATP-dependent RNA helicase DBP3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity); Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.	WD_REPEATS_REGION domain-containing protein.	0.574
DBP3	SNOG_02652	Q0UY62	Q0V012	ATP-dependent RNA helicase DBP3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity); Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.	Uncharacterized protein.	0.594
DBP3	SNOG_03110	Q0UY62	Q0UYQ4	ATP-dependent RNA helicase DBP3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity); Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.	Uncharacterized protein.	0.572
DBP3	SNOG_03348	Q0UY62	Q0UY16	ATP-dependent RNA helicase DBP3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity); Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.	WD_REPEATS_REGION domain-containing protein.	0.503
DBP3	SNOG_03577	Q0UY62	Q0UXD7	ATP-dependent RNA helicase DBP3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity); Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.	WD_REPEATS_REGION domain-containing protein.	0.492
DBP3	SNOG_03884	Q0UY62	Q0UWI0	ATP-dependent RNA helicase DBP3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity); Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.	PINc domain-containing protein.	0.479
DBP3	SNOG_04312	Q0UY62	Q0UVA2	ATP-dependent RNA helicase DBP3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity); Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.	CBF domain-containing protein.	0.547
DBP3	SNOG_04419	Q0UY62	Q0UUZ5	ATP-dependent RNA helicase DBP3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity); Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.	Uncharacterized protein.	0.544
DBP3	SNOG_04633	Q0UY62	Q0UUD1	ATP-dependent RNA helicase DBP3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity); Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.	WD_REPEATS_REGION domain-containing protein.	0.652
DBP3	SNOG_04672	Q0UY62	Q0UU92	ATP-dependent RNA helicase DBP3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity); Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.	Uncharacterized protein.	0.770