(21 nodes) U2 snRNP, and U1 snRNA binding network (Parastagonospora nodorum)

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Your Input:
	SNOG_15992	RRM domain-containing protein. (386 aa)
	SNOG_15866	RRM domain-containing protein. (118 aa)
	SNOG_15022	SF3A2 domain-containing protein. (218 aa)
	SNOG_13779	Uncharacterized protein. (108 aa)
	SNOG_13667	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (97 aa)
	SNOG_11947	Small nuclear ribonucleoprotein Sm D1; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site; Belongs to the snRNP core protein family. (137 aa)
	SNOG_11761	Splicing factor subunit; Belongs to the SF3B5 family. (84 aa)
	SNOG_11135	Matrin-type domain-containing protein. (518 aa)
	SNOG_10452	Small nuclear ribonucleoprotein Sm D2. (133 aa)
	SNOG_10227	Small nuclear ribonucleoprotein Sm D3. (117 aa)
	SNOG_09247	Uncharacterized protein. (306 aa)
	SNOG_08932	Uncharacterized protein. (204 aa)
	PRP5	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily. (1184 aa)
	SNOG_06486	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (127 aa)
	SNOG_04440	Small nuclear ribonucleoprotein G. (84 aa)
	SNOG_04397	SF3b1 domain-containing protein. (1207 aa)
	SNOG_03555	Sm domain-containing protein. (214 aa)
	SNOG_03502	RRM domain-containing protein. (177 aa)
	SNOG_02443	CPSF_A domain-containing protein. (1246 aa)
	SNOG_01768	PSP domain-containing protein. (568 aa)
	SNOG_00186	Uncharacterized protein. (503 aa)

Your Current Organism:

Parastagonospora nodorum

NCBI taxonomy Id: 321614
Other names: P. nodorum SN15, Parastagonospora nodorum SN15, Phaeosphaeria nodorum SN15

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PRP5	SNOG_00186	Q0UN57	Q0V728	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.	Uncharacterized protein.	0.998
PRP5	SNOG_01768	Q0UN57	Q0V2J6	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.	PSP domain-containing protein.	0.986
PRP5	SNOG_02443	Q0UN57	Q0V0M1	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.	CPSF_A domain-containing protein.	0.995
PRP5	SNOG_03502	Q0UN57	Q0UXL2	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.	RRM domain-containing protein.	0.901
PRP5	SNOG_03555	Q0UN57	Q0UXF9	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.	Sm domain-containing protein.	0.969
PRP5	SNOG_04397	Q0UN57	Q0UV17	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.	SF3b1 domain-containing protein.	0.998
PRP5	SNOG_04440	Q0UN57	Q0UUX3	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.	Small nuclear ribonucleoprotein G.	0.967
PRP5	SNOG_06486	Q0UN57	Q0UP28	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.	0.866
PRP5	SNOG_08932	Q0UN57	Q0UH32	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.	Uncharacterized protein.	0.901
PRP5	SNOG_09247	Q0UN57	Q0UG67	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.	Uncharacterized protein.	0.976
PRP5	SNOG_10227	Q0UN57	Q0UDD6	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.	Small nuclear ribonucleoprotein Sm D3.	0.883
PRP5	SNOG_10452	Q0UN57	Q0UCR2	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.	Small nuclear ribonucleoprotein Sm D2.	0.971
PRP5	SNOG_11135	Q0UN57	Q0UAS9	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.	Matrin-type domain-containing protein.	0.997
PRP5	SNOG_11761	Q0UN57	Q0U903	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.	Splicing factor subunit; Belongs to the SF3B5 family.	0.995
PRP5	SNOG_11947	Q0UN57	Q0U8G7	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.	Small nuclear ribonucleoprotein Sm D1; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site; Belongs to the snRNP core protein family.	0.995
PRP5	SNOG_13667	Q0UN57	Q0U3J7	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.960
PRP5	SNOG_13779	Q0UN57	Q0U385	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.	Uncharacterized protein.	0.997
PRP5	SNOG_15022	Q0UN57	Q0TZL0	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.	SF3A2 domain-containing protein.	0.997
PRP5	SNOG_15866	Q0UN57	Q0TX45	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.	RRM domain-containing protein.	0.837
PRP5	SNOG_15992	Q0UN57	Q0TWS0	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.	RRM domain-containing protein.	0.800