(116 nodes) GTP hydrolysis and joining of the 60S ribosomal subunit network (Parastagonospora nodorum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SNOG_07635	Uncharacterized protein. (357 aa)
	SNOG_16548	Uncharacterized protein. (91 aa)
	SNOG_16074	Uncharacterized protein. (131 aa)
	SNOG_15733	60S ribosomal protein L29; Belongs to the eukaryotic ribosomal protein eL29 family. (65 aa)
	SNOG_15604	Uncharacterized protein. (342 aa)
	SNOG_15657	40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family. (202 aa)
	SNOG_15237	60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (316 aa)
	SNOG_14710	Uncharacterized protein. (202 aa)
	SNOG_14766	Uncharacterized protein. (58 aa)
	SNOG_14524	HET domain-containing protein. (816 aa)
	SNOG_14540	Fungal_trans domain-containing protein. (756 aa)
	SNOG_14064	Uncharacterized protein. (189 aa)
	SNOG_13735	40S ribosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family. (134 aa)
	SNOG_13626	Ribosomal_S17_N domain-containing protein; Belongs to the universal ribosomal protein uS17 family. (159 aa)
	SNOG_13569	Uncharacterized protein. (146 aa)
	SNOG_13327	Tr-type G domain-containing protein. (1084 aa)
	SNOG_13252	Tr-type G domain-containing protein. (800 aa)
	SNOG_12195	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family. (122 aa)
	SNOG_12140	Uncharacterized protein. (226 aa)
	SNOG_12114	Uncharacterized protein; Belongs to the universal ribosomal protein uL11 family. (165 aa)
	SNOG_12064	Ribosomal_S10 domain-containing protein. (116 aa)
	SNOG_12022	Uncharacterized protein. (142 aa)
	SNOG_11943	Uncharacterized protein. (217 aa)
	SNOG_11879	HABP4_PAI-RBP1 domain-containing protein. (369 aa)
	SNOG_11861	Ribos_L4_asso_C domain-containing protein. (372 aa)
	SNOG_11745	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (168 aa)
	SNOG_11663	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (460 aa)
	SNOG_11611	60S ribosomal protein L20; Belongs to the eukaryotic ribosomal protein eL20 family. (174 aa)
	SNOG_11071	Uncharacterized protein. (191 aa)
	SNOG_10560	Uncharacterized protein. (285 aa)
	SNOG_10409	Ribosomal_L18_c domain-containing protein. (255 aa)
	SNOG_10263	Uncharacterized protein. (128 aa)
	RPS1	40S ribosomal protein S1; Belongs to the eukaryotic ribosomal protein eS1 family. (255 aa)
	SNOG_09417	Uncharacterized protein. (108 aa)
	SNOG_09286	Uncharacterized protein. (95 aa)
	SNOG_09245	Ribosomal_L28e domain-containing protein. (146 aa)
	SNOG_09234	Uncharacterized protein. (264 aa)
	SNOG_09012	Ribosomal_L23eN domain-containing protein. (152 aa)
	SNOG_08584	Uncharacterized protein. (167 aa)
	COX16	Cytochrome c oxidase assembly protein COX16, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines. Belongs to the COX16 family. (116 aa)
	SNOG_08214	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family. (193 aa)
	SNOG_08190	Uncharacterized protein. (68 aa)
	SNOG_08180	60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. (215 aa)
	SNOG_07837	Uncharacterized protein. (92 aa)
	EGD2	Nascent polypeptide-associated complex subunit alpha; Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of th [...] (211 aa)
	SNOG_07798	Ribosomal_L14e domain-containing protein. (146 aa)
	SNOG_07796	Uncharacterized protein. (344 aa)
	SNOG_07635-2	Uncharacterized protein. (373 aa)
	SNOG_07535	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (239 aa)
	EGD1	Nascent polypeptide-associated complex subunit beta; Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the [...] (160 aa)
	SNOG_07382	Uncharacterized protein. (161 aa)
	SNOG_07046	Uncharacterized protein; Belongs to the EF-1-beta/EF-1-delta family. (231 aa)
	SNOG_07040	HET domain-containing protein. (604 aa)
	SNOG_06942	Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. (217 aa)
	SNOG_06484	WD_REPEATS_REGION domain-containing protein. (221 aa)
	SNOG_06413	Uncharacterized protein. (251 aa)
	SNOG_06402	Uncharacterized protein. (114 aa)
	SNOG_06349	Uncharacterized protein. (165 aa)
	SNOG_06318	Uncharacterized protein. (222 aa)
	SNOG_06213	Ribosomal_L7Ae domain-containing protein. (263 aa)
	SNOG_06038	Tr-type G domain-containing protein. (843 aa)
	SNOG_06036	Uncharacterized protein. (244 aa)
	SNOG_05869	Uncharacterized protein. (523 aa)
	SNOG_05861	Uncharacterized protein. (1064 aa)
	SNOG_05785	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (202 aa)
	RPS0	40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. (301 aa)
	SNOG_05621	WW domain-containing protein. (293 aa)
	SNOG_05397	Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family. (199 aa)
	SNOG_05379	Uncharacterized protein. (267 aa)
	SNOG_05336	Uncharacterized protein. (128 aa)
	SNOG_04945	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family. (145 aa)
	SNOG_04728	Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family. (112 aa)
	SNOG_04399	Ribosomal_S13_N domain-containing protein; Belongs to the universal ribosomal protein uS15 family. (151 aa)
	SNOG_03960	Uncharacterized protein. (163 aa)
	SNOG_03785	60S ribosomal protein L36; Belongs to the eukaryotic ribosomal protein eL36 family. (106 aa)
	SNOG_03650	Uncharacterized protein; Belongs to the eukaryotic ribosomal protein eL38 family. (82 aa)
	SNOG_03556	Uncharacterized protein; Belongs to the universal ribosomal protein uL5 family. (173 aa)
	SNOG_03277	Ribosomal_L18e/L15P domain-containing protein; Belongs to the universal ribosomal protein uL15 family. (148 aa)
	SNOG_03154	Ribosomal_L7Ae domain-containing protein. (109 aa)
	SNOG_03153	Ribosomal_L16 domain-containing protein. (135 aa)
	SNOG_03139	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family. (189 aa)
	SNOG_02602	Uncharacterized protein; Belongs to the eukaryotic ribosomal protein eL42 family. (106 aa)
	SNOG_02568	KOW domain-containing protein. (135 aa)
	SNOG_02412	Uncharacterized protein. (414 aa)
	SNOG_02310	Uncharacterized protein; Belongs to the universal ribosomal protein uL22 family. (274 aa)
	SNOG_02092	Uncharacterized protein. (250 aa)
	SNOG_02088	Uncharacterized protein; Belongs to the universal ribosomal protein uS11 family. (151 aa)
	SNOG_02063	Ribosomal_S7 domain-containing protein; Belongs to the universal ribosomal protein uS7 family. (259 aa)
	SNOG_02050	Uncharacterized protein; Belongs to the universal ribosomal protein uS13 family. (155 aa)
	SNOG_02030	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (97 aa)
	SNOG_02003	Uncharacterized protein; Belongs to the universal ribosomal protein uS8 family. (130 aa)
	SNOG_01985	TCTP domain-containing protein; Belongs to the TCTP family. (169 aa)
	SNOG_01941	Uncharacterized protein. (366 aa)
	SNOG_01936	Ribosomal_L2_C domain-containing protein. (237 aa)
	SNOG_01596	HTH cro/C1-type domain-containing protein. (160 aa)
	SNOG_01334	Ubiquitin-like domain-containing protein. (421 aa)
	SNOG_00986	Uncharacterized protein. (160 aa)
	SNOG_00985	S4 RNA-binding domain-containing protein; Belongs to the universal ribosomal protein uS4 family. (192 aa)
	SNOG_00983	40S ribosomal protein S27. (82 aa)
	SNOG_00903	Uncharacterized protein. (311 aa)
	SNOG_00672	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (261 aa)
	SNOG_00647	Uncharacterized protein. (285 aa)
	SNOG_00646	Uncharacterized protein. (410 aa)
	SNOG_00626	Tr-type G domain-containing protein. (133 aa)
	MEF1	Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. (654 aa)
	cnxG	Molybdopterin synthase sulfur carrier subunit; Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by UBA4. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin. (96 aa)
	SNOG_00586	HET domain-containing protein. (563 aa)
	SNOG_00560	Protein DOM34 homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (407 aa)
	SNOG_00552	Uncharacterized protein. (89 aa)
	SNOG_00472	Uncharacterized protein; Belongs to the universal ribosomal protein uL14 family. (141 aa)
	SNOG_00451	Uncharacterized protein. (114 aa)
	SNOG_00335	Uncharacterized protein. (576 aa)
	SNOG_00241	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family. (262 aa)
	SNOG_00234	Ribosomal protein L37; Binds to the 23S rRNA. (95 aa)
	SNOG_00180	Uncharacterized protein. (332 aa)
	SNOG_00101	Uncharacterized protein. (206 aa)

Your Current Organism:

Parastagonospora nodorum

NCBI taxonomy Id: 321614
Other names: P. nodorum SN15, Parastagonospora nodorum SN15, Phaeosphaeria nodorum SN15

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COX16	EGD1	Q0UIR3	Q0ULD0	Cytochrome c oxidase assembly protein COX16, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines. Belongs to the COX16 family.	Nascent polypeptide-associated complex subunit beta; Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the [...]	0.623
COX16	EGD2	Q0UIR3	Q0UKB5	Cytochrome c oxidase assembly protein COX16, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines. Belongs to the COX16 family.	Nascent polypeptide-associated complex subunit alpha; Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of th [...]	0.648
COX16	MEF1	Q0UIR3	Q0V5T9	Cytochrome c oxidase assembly protein COX16, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines. Belongs to the COX16 family.	Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.	0.440
COX16	RPS0	Q0UIR3	Q0UR95	Cytochrome c oxidase assembly protein COX16, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines. Belongs to the COX16 family.	40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.	0.892
COX16	RPS1	Q0UIR3	Q0UFP1	Cytochrome c oxidase assembly protein COX16, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines. Belongs to the COX16 family.	40S ribosomal protein S1; Belongs to the eukaryotic ribosomal protein eS1 family.	0.922
COX16	SNOG_00101	Q0UIR3	Q0V7B3	Cytochrome c oxidase assembly protein COX16, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines. Belongs to the COX16 family.	Uncharacterized protein.	0.769
COX16	SNOG_00180	Q0UIR3	Q0V734	Cytochrome c oxidase assembly protein COX16, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines. Belongs to the COX16 family.	Uncharacterized protein.	0.699
COX16	SNOG_00234	Q0UIR3	Q0V6Y0	Cytochrome c oxidase assembly protein COX16, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines. Belongs to the COX16 family.	Ribosomal protein L37; Binds to the 23S rRNA.	0.856
COX16	SNOG_00241	Q0UIR3	Q0V6X3	Cytochrome c oxidase assembly protein COX16, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines. Belongs to the COX16 family.	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family.	0.919
COX16	SNOG_00335	Q0UIR3	Q0V6M9	Cytochrome c oxidase assembly protein COX16, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines. Belongs to the COX16 family.	Uncharacterized protein.	0.794
COX16	SNOG_00451	Q0UIR3	Q0V6B3	Cytochrome c oxidase assembly protein COX16, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines. Belongs to the COX16 family.	Uncharacterized protein.	0.920
COX16	SNOG_00472	Q0UIR3	Q0V692	Cytochrome c oxidase assembly protein COX16, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines. Belongs to the COX16 family.	Uncharacterized protein; Belongs to the universal ribosomal protein uL14 family.	0.912
COX16	SNOG_00552	Q0UIR3	Q0V611	Cytochrome c oxidase assembly protein COX16, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines. Belongs to the COX16 family.	Uncharacterized protein.	0.916
COX16	SNOG_00560	Q0UIR3	Q0V604	Cytochrome c oxidase assembly protein COX16, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines. Belongs to the COX16 family.	Protein DOM34 homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs.	0.480
COX16	SNOG_00586	Q0UIR3	Q0V5X8	Cytochrome c oxidase assembly protein COX16, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines. Belongs to the COX16 family.	HET domain-containing protein.	0.526
COX16	SNOG_00626	Q0UIR3	Q0V5T8	Cytochrome c oxidase assembly protein COX16, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines. Belongs to the COX16 family.	Tr-type G domain-containing protein.	0.440
COX16	SNOG_00646	Q0UIR3	Q0V5R8	Cytochrome c oxidase assembly protein COX16, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines. Belongs to the COX16 family.	Uncharacterized protein.	0.856
COX16	SNOG_00647	Q0UIR3	Q0V5R7	Cytochrome c oxidase assembly protein COX16, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines. Belongs to the COX16 family.	Uncharacterized protein.	0.770
COX16	SNOG_00672	Q0UIR3	Q0V5P2	Cytochrome c oxidase assembly protein COX16, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines. Belongs to the COX16 family.	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	0.919
COX16	SNOG_00903	Q0UIR3	Q0V511	Cytochrome c oxidase assembly protein COX16, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines. Belongs to the COX16 family.	Uncharacterized protein.	0.810