(45 nodes) Ribonuclease H-like superfamily network (Parastagonospora nodorum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SNOG_08384	Exonuclease domain-containing protein. (473 aa)
	SNOG_08383	DNA polymerase. (1462 aa)
	SNOG_06565	Uncharacterized protein. (1004 aa)
	PAN2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1129 aa)
	SNOG_05779	Uncharacterized protein. (576 aa)
	SNOG_01231	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (345 aa)
	SNOG_00690	DNA polymerase. (1584 aa)
	SNOG_16572	Uncharacterized protein. (449 aa)
	SNOG_16556	RNase H domain-containing protein. (602 aa)
	SNOG_16530	Exonuclease domain-containing protein. (1150 aa)
	SNOG_00449	MPN domain-containing protein. (2308 aa)
	SNOG_16500	Exonuclease domain-containing protein. (356 aa)
	SNOG_16122	Piwi domain-containing protein. (398 aa)
	SNOG_15995	Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (319 aa)
	SNOG_15524	Uncharacterized protein. (606 aa)
	SNOG_14657	3'-5' exonuclease domain-containing protein. (279 aa)
	SNOG_14604	Uncharacterized protein. (668 aa)
	SNOG_13731	RNase H domain-containing protein. (225 aa)
	SNOG_12967	Uncharacterized protein. (606 aa)
	SNOG_05653	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1412 aa)
	SNOG_05578	RNase H domain-containing protein. (613 aa)
	SNOG_05333	Ydc2-catalyt domain-containing protein. (397 aa)
	SNOG_03678	3'-5' exonuclease domain-containing protein. (721 aa)
	SNOG_02376	RNase H domain-containing protein. (505 aa)
	SNOG_01745	Uncharacterized protein. (628 aa)
	SNOG_12738	Piwi domain-containing protein. (886 aa)
	SNOG_12458	Uncharacterized protein. (393 aa)
	SNOG_12417	Uncharacterized protein. (318 aa)
	SNOG_12415	Uncharacterized protein. (593 aa)
	SNOG_12414	Uncharacterized protein. (540 aa)
	SNOG_12309	Piwi domain-containing protein. (903 aa)
	SNOG_12281	Uncharacterized protein. (405 aa)
	SNOG_12157	Uncharacterized protein. (1003 aa)
	SNOG_11959	HRDC domain-containing protein. (805 aa)
	SNOG_11951	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2236 aa)
	SNOG_10950	HRDC domain-containing protein. (637 aa)
	SNOG_10753	DNA polymerase. (1115 aa)
	SNOG_10708	Exonuclease domain-containing protein. (663 aa)
	SNOG_10566	Piwi domain-containing protein. (981 aa)
	SNOG_10546	Piwi domain-containing protein. (802 aa)
	SNOG_10544	Piwi domain-containing protein. (1093 aa)
	SNOG_10489	POLAc domain-containing protein. (1130 aa)
	SNOG_10420	Piwi domain-containing protein. (1148 aa)
	SNOG_10169	Exonuclease domain-containing protein. (223 aa)
	SNOG_09149	Uncharacterized protein. (497 aa)

Your Current Organism:

Parastagonospora nodorum

NCBI taxonomy Id: 321614
Other names: P. nodorum SN15, Parastagonospora nodorum SN15, Phaeosphaeria nodorum SN15

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PAN2	SNOG_09149	Q0UPL5	Q0UGG5	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	Uncharacterized protein.	0.635
PAN2	SNOG_12967	Q0UPL5	Q0U5J7	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	Uncharacterized protein.	0.514
SNOG_00690	SNOG_01231	Q0V5M4	Q0V433	DNA polymerase.	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	0.483
SNOG_00690	SNOG_03678	Q0V5M4	Q0UX36	DNA polymerase.	3'-5' exonuclease domain-containing protein.	0.793
SNOG_00690	SNOG_08383	Q0V5M4	Q0UIN1	DNA polymerase.	DNA polymerase.	0.687
SNOG_00690	SNOG_10489	Q0V5M4	Q0UCM4	DNA polymerase.	POLAc domain-containing protein.	0.494
SNOG_00690	SNOG_10753	Q0V5M4	Q0UBW1	DNA polymerase.	DNA polymerase.	0.875
SNOG_00690	SNOG_10950	Q0V5M4	Q0UBB4	DNA polymerase.	HRDC domain-containing protein.	0.793
SNOG_00690	SNOG_11951	Q0V5M4	Q0U8G3	DNA polymerase.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.906
SNOG_01231	SNOG_00690	Q0V433	Q0V5M4	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	DNA polymerase.	0.483
SNOG_01231	SNOG_03678	Q0V433	Q0UX36	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	3'-5' exonuclease domain-containing protein.	0.551
SNOG_01231	SNOG_05578	Q0V433	Q0URN5	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	RNase H domain-containing protein.	0.790
SNOG_01231	SNOG_08383	Q0V433	Q0UIN1	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	DNA polymerase.	0.681
SNOG_01231	SNOG_10753	Q0V433	Q0UBW1	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	DNA polymerase.	0.668
SNOG_01231	SNOG_10950	Q0V433	Q0UBB4	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	HRDC domain-containing protein.	0.551
SNOG_01231	SNOG_11951	Q0V433	Q0U8G3	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.883
SNOG_01231	SNOG_13731	Q0V433	Q0U3D3	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	RNase H domain-containing protein.	0.790
SNOG_01231	SNOG_15995	Q0V433	Q0TWR7	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.742
SNOG_03678	SNOG_00690	Q0UX36	Q0V5M4	3'-5' exonuclease domain-containing protein.	DNA polymerase.	0.793
SNOG_03678	SNOG_01231	Q0UX36	Q0V433	3'-5' exonuclease domain-containing protein.	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	0.551