STRINGSTRING
metE metE LSEI_0600 LSEI_0600 LSEI_0480 LSEI_0480 LSEI_0479 LSEI_0479 asd asd LSEI_0099 LSEI_0099 rsmA rsmA ldh-2 ldh-2 LSEI_2747 LSEI_2747 LSEI_2607 LSEI_2607 LSEI_2152 LSEI_2152 LSEI_2151 LSEI_2151 LSEI_2041 LSEI_2041 scpB scpB LSEI_1310 LSEI_1310 LSEI_1288 LSEI_1288 LSEI_1245 LSEI_1245 LSEI_1200 LSEI_1200 LSEI_1199 LSEI_1199 LSEI_1029 LSEI_1029 LSEI_0894 LSEI_0894 metK metK LSEI_0802 LSEI_0802 luxS luxS LSEI_0764 LSEI_0764 ldh ldh
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
metEMethionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (761 aa)
LSEI_0600Cystathionine gamma-synthase. (378 aa)
LSEI_0480Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (309 aa)
LSEI_0479Homoserine trans-succinylase; Transfers an acetyl group from acetyl-CoA to L-serine, forming acetyl-L-serine; Belongs to the MetA family. (271 aa)
asdAspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (352 aa)
LSEI_0099Aspartate kinase; Belongs to the aspartokinase family. (459 aa)
rsmADimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (298 aa)
ldh-2L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (326 aa)
LSEI_2747Aminotransferase. (527 aa)
LSEI_2607Malate dehydrogenase (NAD); Belongs to the LDH/MDH superfamily. (301 aa)
LSEI_2152Aspartate kinase; Belongs to the aspartokinase family. (448 aa)
LSEI_2151Homoserine dehydrogenase. (399 aa)
LSEI_2041Branched chain amino acid aminotransferase apoenzyme. (343 aa)
scpBCondensin subunit ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (206 aa)
LSEI_1310Malate/lactate dehydrogenase. (296 aa)
LSEI_1288Methylthioadenosine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (236 aa)
LSEI_1245GAF domain-containing protein. (160 aa)
LSEI_1200L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (288 aa)
LSEI_1199L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (221 aa)
LSEI_1029Adenine-specific DNA methylase. (336 aa)
LSEI_0894Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities. (401 aa)
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (394 aa)
LSEI_0802CBS domain containing protein. (161 aa)
luxSAutoinducer AI2 synthesis LuxS-like protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (157 aa)
LSEI_0764Methionine synthase II (cobalamin-independent). (377 aa)
ldhMalate dehydrogenase (NAD); Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (312 aa)
Your Current Organism:
Lactobacillus paracasei
NCBI taxonomy Id: 321967
Other names: L. paracasei ATCC 334, Lactobacillus casei ATCC 334, Lactobacillus casei str. ATCC 334, Lactobacillus casei strain ATCC 334, Lactobacillus paracasei ATCC 334
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