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| | ACO76607.1 | 4Fe-4S ferredoxin. (83 aa) |
| | nifB | Nitrogenase cofactor biosynthesis protein. (503 aa) |
| | rnfB1 | Electron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. (174 aa) |
| | rnfC1 | Electron transport complex, RnfABCDGE type, C subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. (496 aa) |
| | hoxK | Uptake hydrogenase small subunit (Precursor), HoxK. (358 aa) |
| | ACO81022.1 | L-arabonate dehydratase; Belongs to the IlvD/Edd family. (578 aa) |
| | anfU | NifU C-terminal domain-containing protein, AnfU. (96 aa) |
| | anfH | Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family. (275 aa) |
| | anfD | Nitrogenase iron-iron protein, alpha chain. (518 aa) |
| | anfK | Fe-only nitrogenase, beta subunit; Belongs to the NifD/NifK/NifE/NifN family. (462 aa) |
| | ACO80844.1 | Oxidoreductase protein. (322 aa) |
| | erpA | Essential respiratory protein A, ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. (116 aa) |
| | ACO80678.1 | Conserved hypothetical protein. (134 aa) |
| | gltB | Glutamate synthase large subunit protein. (1480 aa) |
| | gltD | Glutamate synthase small subunit 2. (473 aa) |
| | thiC | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (628 aa) |
| | glcF | Glycolate oxidase iron-sulfur subunit, glcF. (405 aa) |
| | ACO80432.1 | Fe-S/FAD domain protein. (938 aa) |
| | ACO80430.1 | Iron-sulfur cluster binding protein-like protein. (482 aa) |
| | ACO80429.1 | Conserved hypothetical protein. (274 aa) |
| | ACO80384.1 | Conserved hypothetical protein. (105 aa) |
| | ACO80347.1 | Rieske type ferredoxin. (122 aa) |
| | ACO80346.1 | Aromatic ring hydroxylating dioxygenase, alpha subunit. (448 aa) |
| | ACO80337.1 | Ferredoxin:Oxidoreductase FAD/NAD(P)-binding. (333 aa) |
| | ACO80311.1 | Lysine 2,3-aminomutase. (433 aa) |
| | pqqE | Coenzyme PQQ biosynthesis E; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ). (383 aa) |
| | iscS | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. (404 aa) |
| | iscU | Iron-sulfur cluster assembly scaffold protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. (128 aa) |
| | iscA | Iron-sulfur biogenesis protein; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. (107 aa) |
| | fdx | Isc ferredoxin. (113 aa) |
| | rlmN | Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (381 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (370 aa) |
| | ACO80126.1 | Oxidoreductase/nitrogenase, component 1; Belongs to the NifD/NifK/NifE/NifN family. (464 aa) |
| | ACO80109.1 | Ferredoxin. (122 aa) |
| | fdxA | Ferredoxin I; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (107 aa) |
| | fumB | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (503 aa) |
| | rimO | Ribosomal protein S12 methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (440 aa) |
| | rumA | 23S rRNA (uracil-5-)-methyltransferase RumA; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. (454 aa) |
| | queE | Radical SAM protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (193 aa) |
| | ACO79703.1 | Iron-sulfur binding oxidoreductase. (148 aa) |
| | ACO79701.1 | Molybdenum cofactor biosynthesis protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (287 aa) |
| | nadA | Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. (352 aa) |
| | dmpP | Phenol hydroxylase, Ferredoxin subunit. (353 aa) |
| | xylT | Ferredoxin, XylT. (104 aa) |
| | benC | Benzoate 1,2-Dioxygenase Reductase. (336 aa) |
| | benA | Benzoate-1,2-dioxygenase oxygenase component, alpha subunit. (453 aa) |
| | lipA | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (325 aa) |
| | xdhA | Xanthine dehydrogenase, small subunit. (496 aa) |
| | cysH | Phosphoadenosine phosphosulfate reductase CysH-type; Reduction of activated sulfate into sulfite. (244 aa) |
| | acnD | 2-methylisocitrate dehydratase, Fe/S-dependent; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (867 aa) |
| | nasB | Assimilatory nitrate reductase, NasB; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. (901 aa) |
| | ACO77016.1 | Elongator protein 3, MiaB/NifB, Radical SAM superfamily protein. (757 aa) |
| | queG | Iron-sulfur cluster binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (354 aa) |
| | bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (351 aa) |
| | mutY | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. (362 aa) |
| | cooF | Iron-sulfur cluster-binding protein CooF. (185 aa) |
| | cooS | Carbon-monoxide dehydrogenase, catalytic subunit. (632 aa) |
| | hoxY | Soluble hydrogenase delta subunit, HoxY. (256 aa) |
| | ACO76694.1 | Soluble hydrogenase gamma subunit. (276 aa) |
| | ACO76692.1 | Soluble hydrogenase, alpha or beta chain. (382 aa) |
| | moaA | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (335 aa) |
| | fdhH | Formate dehydrogenase, beta subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (297 aa) |
| | fdhA | Formate dehydrogenase, alpha subunit. (1018 aa) |
| | ACO78524.1 | Assimilatory nitrite reductase, small subunit. (108 aa) |
| | nasA | Assimilatory Nitrite reductase,large subunit; NasA; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (816 aa) |
| | acnB | Aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. (869 aa) |
| | ACO78764.1 | Ferredoxin:(2Fe-2S)-binding protein. (156 aa) |
| | sdaA | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa) |
| | ACO78783.1 | Oxidoreductase iron sulphur binding subunit. (152 aa) |
| | edd-2 | 6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (608 aa) |
| | cysI | Sulfite reductase, beta subunit (hemoprotein). (552 aa) |
| | nuoB | NADH-ubiquinone oxidoreductase, chain beta; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (224 aa) |
| | nuoE | NADH-ubiquinone oxidoreductase, chain E. (164 aa) |
| | nuoF | NADH-quinone oxidoreductase, F subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (449 aa) |
| | nuoG | NADH-quinone oxidoreductase, chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (903 aa) |
| | nuoI | NADH-quinone oxidoreductase, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (182 aa) |
| | nfuA | NfuA protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. (194 aa) |
| | ACO79104.1 | Fe-S cluster redox enzyme, radical SAM family; Belongs to the radical SAM superfamily. RlmN family. (344 aa) |
| | sdhB | Succinate dehydrogenase iron-sulfur subunit. (233 aa) |
| | moaA-2 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (331 aa) |
| | lapQ | Ferredoxin. (121 aa) |
| | lapP | Multi-component phenol hydoxylase, reductase subunit; LapP. (353 aa) |
| | ACO79243.1 | uracil-DNA glycosylase-like protein. (188 aa) |
| | ttdA | L-tartrate dehydratase alpha subunit. (286 aa) |
| | cas4 | CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (199 aa) |
| | ttcA | PP-loop ATPase protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (274 aa) |
| | leuC | 3-isopropylmalate dehydratase large subunit LeuC; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (474 aa) |
| | ACO79610.1 | Hypothetical protein. (263 aa) |
| | ACO79667.1 | Conserved hypothetical protein. (120 aa) |
| | ACO81193.1 | Glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily. (109 aa) |
| | ACO81189.1 | Ferredoxin protein. (92 aa) |
| | ACO78266.1 | MoaA, NifB, PqqE, radical SAM superfamily protein. (377 aa) |
| | acnA | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (895 aa) |
| | ccoG | Cytochrome c oxidase accessory protein CcoG. (470 aa) |
| | hemN | Oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (458 aa) |
| | dinG | ATP-dependent helicase; DNA-dependent ATPase and 5'-3' DNA helicase. (714 aa) |
| | apbC | Small P-loop ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (364 aa) |
| | rnfB | Electron transport complex, subunit B; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. (187 aa) |
| | rnfC | Electron transport complex, subunit C; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. (688 aa) |
| | nth | Endonuclease III/Nth; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (212 aa) |
| | ACO77953.1 | Electron-transferring-flavoprotein ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (549 aa) |
| | ACO77858.1 | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (549 aa) |
| | edd-1 | 6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (608 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (612 aa) |
| | ACO76560.1 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (373 aa) |
| | vnfU | NifU C-terminal domain-containing protein, VnfU. (96 aa) |
| | vnfH | Vanadium nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family. (290 aa) |
| | vnfF | Vanadium nitrogenase ferredoxin, vnfF. (65 aa) |
| | vnfD | Vanadium nitrogenase, alpha subunit, vnfD. (474 aa) |
| | vnfK | Vanadium nitrogenase beta subunit, vnfK; Belongs to the NifD/NifK/NifE/NifN family. (475 aa) |
| | ACO76605.1 | Conserved hypothetical protein. (451 aa) |
| | nifS | Nitrogen fixation cysteine desulfurase, nifS; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. (402 aa) |
| | nifU | Nitrogen fixation Fe-S cluster scaffold protein; Involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins. (312 aa) |
| | iscAnif | Nitrogen fixation Fe-S cluster assembly protein IscAnif; Belongs to the HesB/IscA family. (107 aa) |
| | fesII | Nitrogen fixation (2Fe-2S) ferredoxin (Shethna protein), FeSII; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. Might be involved in nitrogen fixation; Belongs to the 2Fe2S Shethna-type ferredoxin family. (107 aa) |
| | ACO76415.1 | Nitrogen fixation (4Fe-4S) ferredoxin-like protein. (51 aa) |
| | nifK | Nitrogenase molybdenum-iron protein beta chain; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation; Belongs to the NifD/NifK/NifE/NifN family. (523 aa) |
| | nifD | Nitrogenase molybdenum-iron protein alpha chain:Nitrogenase component I, alpha chain. (492 aa) |
| | nifH | Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family. (290 aa) |
| | ACO78269.1 | MoaA, NifB, PqqE, radical SAM superfamily protein. (470 aa) |
| | asfB | 4Fe-4S ferredoxin protein. (130 aa) |
| | ACO77772.1 | Conserved hypothetical protein. (105 aa) |
| | ACO77731.1 | Electron-transferring-flavoprotein ubiquinone oxido-reductase; Accepts electrons from ETF and reduces ubiquinone. (550 aa) |
| | nqrF | NADH:ubiquinone oxidoreductase, Na(+)-translocating protein, subunit F; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway. (407 aa) |
| | ACO77621.1 | Glutaredoxin4 protein; Belongs to the glutaredoxin family. Monothiol subfamily. (108 aa) |
| | petA | Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (134 aa) |
| | ACO77516.1 | BolA-like protein; Belongs to the BolA/IbaG family. (79 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (315 aa) |
| | fixX | FixX ferredoxin-like protein; Could be a 3Fe-4S cluster-containing protein. (94 aa) |
| | ACO77282.1 | 4Fe-4S ferredoxin, iron-sulfur binding domain protein. (72 aa) |
| | leuC2 | 3-isopropylmalate dehydratase large subunit, LeuC2; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (473 aa) |
| | miaB | tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (442 aa) |
