(38 nodes) Organic acid catabolic process network (Nitrobacter hamburgensis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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experimentally determined

Predicted Interactions

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Your Input:
	Nham_1256	Conserved hypothetical protein. (258 aa)
	Nham_1291	Fumarylacetoacetate (FAA) hydrolase. (234 aa)
	Nham_1470	3-hydroxyisobutyrate dehydrogenase. (289 aa)
	gcvP	Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (958 aa)
	gcvH	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (121 aa)
	Nham_1620	Glycine cleavage system T protein. (387 aa)
	Nham_2300	L-lysine 2,3-aminomutase. (366 aa)
	anmK	Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (366 aa)
	Nham_2556	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (299 aa)
	Nham_2664	L-threonine ammonia-lyase. (415 aa)
	Nham_2698	D-amino-acid dehydrogenase. (433 aa)
	Nham_2706	MaoC-like dehydratase. (150 aa)
	Nham_2803	Hypothetical protein; Belongs to the CoA-transferase III family. (181 aa)
	Nham_2804	Serine--glyoxylate transaminase. (399 aa)
	Nham_2891	Glycine oxidase. (338 aa)
	Nham_3270	6-phosphogluconate dehydrogenase (decarboxylating). (337 aa)
	Nham_3398	L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1017 aa)
	Nham_3480	Electron transfer flavoprotein, alpha subunit. (314 aa)
	Nham_3973	Amidohydrolase. (409 aa)
	Nham_0051	Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (479 aa)
	Nham_0071	Twin-arginine translocation pathway signal. (504 aa)
	Nham_0357	3-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (707 aa)
	Nham_0613	Amine oxidase. (419 aa)
	hmgA	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (448 aa)
	Nham_0924	Monooxygenase, FAD-binding protein. (541 aa)
	Nham_0926	Fumarylacetoacetate hydrolase. (433 aa)
	Nham_0928	Phenylacetate-CoA oxygenase, PaaG subunit. (329 aa)
	Nham_0929	Phenylacetic acid degradation B. (94 aa)
	Nham_0930	Phenylacetate-CoA oxygenase, PaaI subunit. (283 aa)
	Nham_0931	Phenylacetate-CoA oxygenase, PaaJ subunit. (174 aa)
	Nham_0933	Phenylacetic acid catabolic. (250 aa)
	Nham_0934	Phenylacetic acid degradation protein paaN. (691 aa)
	Nham_0936	phenylacetate-CoA ligase. (105 aa)
	Nham_0937	Phenylacetic acid degradation protein PaaD. (149 aa)
	slyX	SlyX; Belongs to the SlyX family. (70 aa)
	Nham_1087	3-hydroxyacyl-CoA dehydrogenase. (696 aa)
	Nham_1142	N-formylglutamate amidohydrolase. (295 aa)
	Nham_1240	FAD dependent oxidoreductase. (367 aa)

Your Current Organism:

Nitrobacter hamburgensis

NCBI taxonomy Id: 323097
Other names: N. hamburgensis X14, Nitrobacter hamburgensis X14, Nitrobacter hamburgensis str. X14, Nitrobacter hamburgensis strain X14

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Nham_0357	Nham_0926	Nham_0357	Nham_0926	3-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Fumarylacetoacetate hydrolase.	0.459
Nham_0357	Nham_0929	Nham_0357	Nham_0929	3-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Phenylacetic acid degradation B.	0.473
Nham_0357	Nham_0934	Nham_0357	Nham_0934	3-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Phenylacetic acid degradation protein paaN.	0.801
Nham_0357	Nham_0936	Nham_0357	Nham_0936	3-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	phenylacetate-CoA ligase.	0.510
Nham_0357	Nham_0937	Nham_0357	Nham_0937	3-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Phenylacetic acid degradation protein PaaD.	0.480
Nham_0357	Nham_1087	Nham_0357	Nham_1087	3-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxyacyl-CoA dehydrogenase.	0.969
Nham_0357	Nham_2706	Nham_0357	Nham_2706	3-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	MaoC-like dehydratase.	0.499
Nham_0357	Nham_2803	Nham_0357	Nham_2803	3-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Hypothetical protein; Belongs to the CoA-transferase III family.	0.520
Nham_0357	Nham_3480	Nham_0357	Nham_3480	3-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Electron transfer flavoprotein, alpha subunit.	0.818
Nham_0357	gcvP	Nham_0357	Nham_1618	3-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	0.467
Nham_0924	Nham_0926	Nham_0924	Nham_0926	Monooxygenase, FAD-binding protein.	Fumarylacetoacetate hydrolase.	0.640
Nham_0924	Nham_0937	Nham_0924	Nham_0937	Monooxygenase, FAD-binding protein.	Phenylacetic acid degradation protein PaaD.	0.425
Nham_0924	hmgA	Nham_0924	Nham_0921	Monooxygenase, FAD-binding protein.	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	0.930
Nham_0926	Nham_0357	Nham_0926	Nham_0357	Fumarylacetoacetate hydrolase.	3-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.459
Nham_0926	Nham_0924	Nham_0926	Nham_0924	Fumarylacetoacetate hydrolase.	Monooxygenase, FAD-binding protein.	0.640
Nham_0926	Nham_0928	Nham_0926	Nham_0928	Fumarylacetoacetate hydrolase.	Phenylacetate-CoA oxygenase, PaaG subunit.	0.400
Nham_0926	Nham_0934	Nham_0926	Nham_0934	Fumarylacetoacetate hydrolase.	Phenylacetic acid degradation protein paaN.	0.574
Nham_0926	Nham_1291	Nham_0926	Nham_1291	Fumarylacetoacetate hydrolase.	Fumarylacetoacetate (FAA) hydrolase.	0.900
Nham_0926	hmgA	Nham_0926	Nham_0921	Fumarylacetoacetate hydrolase.	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	0.984
Nham_0928	Nham_0926	Nham_0928	Nham_0926	Phenylacetate-CoA oxygenase, PaaG subunit.	Fumarylacetoacetate hydrolase.	0.400