STRINGSTRING
hisI hisI purQ purQ Nham_1623 Nham_1623 alaS alaS Nham_1620 Nham_1620 gcvH gcvH gcvP gcvP fabH fabH plsX plsX Nham_1579 Nham_1579 Nham_1520 Nham_1520 Nham_1506 Nham_1506 Nham_1505 Nham_1505 Nham_1504 Nham_1504 Nham_1503 Nham_1503 Nham_1500 Nham_1500 Nham_1490 Nham_1490 cysS cysS Nham_1483 Nham_1483 gph gph Nham_1334 Nham_1334 Nham_1314 Nham_1314 Nham_1291 Nham_1291 Nham_1256 Nham_1256 Nham_1240 Nham_1240 Nham_1218 Nham_1218 Nham_1142 Nham_1142 Nham_1138 Nham_1138 Nham_1137 Nham_1137 Nham_1119 Nham_1119 Nham_1118 Nham_1118 Nham_1112 Nham_1112 aroE aroE Nham_1103 Nham_1103 Nham_1097 Nham_1097 Nham_1088 Nham_1088 Nham_1087 Nham_1087 slyX slyX Nham_1057 Nham_1057 Nham_0996 Nham_0996 Nham_0984 Nham_0984 Nham_0938 Nham_0938 Nham_0937 Nham_0937 Nham_0936 Nham_0936 Nham_0934 Nham_0934 Nham_0933 Nham_0933 Nham_0931 Nham_0931 Nham_0930 Nham_0930 Nham_0929 Nham_0929 Nham_4023 Nham_4023 Nham_4010 Nham_4010 Nham_3973 Nham_3973 Nham_3748 Nham_3748 ispH-2 ispH-2 thrB thrB Nham_3734 Nham_3734 argB argB dapD dapD dapE dapE metE metE argG argG Nham_3600 Nham_3600 leuB leuB asd asd leuD leuD leuC leuC dapF dapF glcB glcB Nham_3548 Nham_3548 Nham_3534 Nham_3534 pgk pgk Nham_3531 Nham_3531 Nham_3505 Nham_3505 Nham_3486 Nham_3486 Nham_3480 Nham_3480 Nham_3479 Nham_3479 argH argH lysA lysA Nham_3398 Nham_3398 Nham_3270 Nham_3270 tal tal Nham_3254 Nham_3254 Nham_3238 Nham_3238 ispE ispE glyQ glyQ glyS glyS Nham_3204 Nham_3204 Nham_3203 Nham_3203 hisG hisG Nham_3187 Nham_3187 ileS ileS Nham_3157 Nham_3157 hisS hisS Nham_3139 Nham_3139 Nham_3126 Nham_3126 Nham_3111 Nham_3111 pdhA-2 pdhA-2 Nham_3108 Nham_3108 Nham_3107 Nham_3107 proC proC Nham_3099 Nham_3099 Nham_3098 Nham_3098 Nham_3038 Nham_3038 Nham_2981 Nham_2981 Nham_2951 Nham_2951 Nham_2916 Nham_2916 Nham_2891 Nham_2891 carB carB carA carA nadA nadA Nham_2816 Nham_2816 bioD bioD Nham_2814 Nham_2814 Nham_2804 Nham_2804 Nham_2803 Nham_2803 Nham_2755 Nham_2755 fumC fumC Nham_2729 Nham_2729 Nham_2724 Nham_2724 Nham_2721 Nham_2721 ilvC ilvC leuA leuA Nham_2706 Nham_2706 Nham_2702 Nham_2702 Nham_2698 Nham_2698 ppc ppc Nham_2680 Nham_2680 ispH ispH Nham_2676 Nham_2676 Nham_2664 Nham_2664 Nham_2663 Nham_2663 Nham_2646 Nham_2646 Nham_2635 Nham_2635 Nham_2634 Nham_2634 Nham_2633 Nham_2633 Nham_2592 Nham_2592 Nham_2579 Nham_2579 Nham_2556 Nham_2556 Nham_2555 Nham_2555 Nham_2554 Nham_2554 guaA guaA Nham_2458 Nham_2458 Nham_2432 Nham_2432 panC panC Nham_2354 Nham_2354 acpP acpP Nham_2351 Nham_2351 tyrS tyrS anmK anmK Nham_2329 Nham_2329 Nham_2325 Nham_2325 argC argC Nham_2310 Nham_2310 Nham_2309 Nham_2309 Nham_2301 Nham_2301 Nham_2300 Nham_2300 purF purF Nham_2290 Nham_2290 pyrB pyrB dapA dapA acpS acpS Nham_0866 Nham_0866 Nham_0849 Nham_0849 aroC aroC Nham_0769 Nham_0769 Nham_0759 Nham_0759 Nham_0754 Nham_0754 glmS glmS Nham_2067 Nham_2067 Nham_2072 Nham_2072 Nham_2054 Nham_2054 Nham_2051 Nham_2051 metG metG Nham_2005 Nham_2005 Nham_1875 Nham_1875 Nham_1840 Nham_1840 ispDF ispDF lipA lipA valS valS glyA glyA serS serS Nham_1773 Nham_1773 argS argS Nham_1751 Nham_1751 Nham_1750 Nham_1750 pdhA pdhA eno eno kdsA kdsA pyrG pyrG tpiA tpiA trpD trpD trpC trpC glnS glnS gltX gltX fabZ fabZ dxr dxr panB panB thrS thrS Nham_0684 Nham_0684 cysI cysI Nham_0682 Nham_0682 metXA metXA Nham_0675 Nham_0675 hisC hisC Nham_0673 Nham_0673 argF argF argD argD ispG ispG Nham_0613 Nham_0613 folD folD Nham_0563 Nham_0563 acsA acsA mdh mdh Nham_0542 Nham_0542 Nham_0541 Nham_0541 Nham_0539 Nham_0539 proA proA proB proB aroB aroB aroK aroK accA accA argJ argJ Nham_0472 Nham_0472 gloB gloB Nham_0447 Nham_0447 Nham_0422 Nham_0422 Nham_0408 Nham_0408 Nham_0365 Nham_0365 Nham_0364 Nham_0364 Nham_0363 Nham_0363 Nham_0357 Nham_0357 hisD hisD bioB bioB Nham_0262 Nham_0262 metZ metZ lysS lysS Nham_0186 Nham_0186 ilvD ilvD aroA aroA gpmA gpmA dapB dapB hisE hisE hisF hisF hisA hisA hisH hisH hisB hisB leuS leuS Nham_0089 Nham_0089 pheS pheS pheT pheT Nham_0071 Nham_0071 Nham_0068 Nham_0068 trpF trpF trpB trpB trpA trpA accD accD Nham_0060 Nham_0060 Nham_0051 Nham_0051 fabA fabA Nham_0041 Nham_0041 Nham_0040 Nham_0040 trpS trpS Nham_2234 Nham_2234 proS proS Nham_2189 Nham_2189 Nham_2188 Nham_2188 aroQ aroQ Nham_2183 Nham_2183 Nham_2180 Nham_2180 Nham_2145 Nham_2145 Nham_2125 Nham_2125 aspS aspS Nham_2110 Nham_2110 Nham_2108 Nham_2108 Nham_2101 Nham_2101 Nham_0928 Nham_0928 Nham_0926 Nham_0926 Nham_0924 Nham_0924 Nham_0922 Nham_0922 hmgA hmgA Nham_0920 Nham_0920 Nham_0914 Nham_0914 Nham_0911 Nham_0911
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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gene neighborhood
gene fusions
gene co-occurrence
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hisIphosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (147 aa)
purQPhosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (233 aa)
Nham_1623Isocitrate dehydrogenase (NADP); Belongs to the isocitrate and isopropylmalate dehydrogenases family. (405 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (897 aa)
Nham_1620Glycine cleavage system T protein. (387 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (121 aa)
gcvPGlycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (958 aa)
fabH3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (325 aa)
plsXPhosphate:acyl-[acyl carrier protein] acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (354 aa)
Nham_1579propionyl-CoA carboxylase carboxyltransferase subunit. (523 aa)
Nham_1520Transcription factor jumonji/aspartyl beta-hydroxylase. (313 aa)
Nham_1506Phosphopantetheine-binding protein. (93 aa)
Nham_1505Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ. (157 aa)
Nham_1504Beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (401 aa)
Nham_1503Beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (423 aa)
Nham_1500Aminotransferase. (384 aa)
Nham_14902-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (532 aa)
cysScysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (482 aa)
Nham_14833-deoxy-D-arabinoheptulosonate-7-phosphate synthase. (462 aa)
gphPhosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (231 aa)
Nham_1334Pyridoxal-dependent decarboxylase. (497 aa)
Nham_1314Mandelate racemase/muconate lactonizing enzyme. (336 aa)
Nham_1291Fumarylacetoacetate (FAA) hydrolase. (234 aa)
Nham_1256Conserved hypothetical protein. (258 aa)
Nham_1240FAD dependent oxidoreductase. (367 aa)
Nham_1218Pyruvate kinase; Belongs to the pyruvate kinase family. (478 aa)
Nham_1142N-formylglutamate amidohydrolase. (295 aa)
Nham_1138Glutamate synthase (NADH) large subunit. (1587 aa)
Nham_1137Glutamate synthase (NADH) small subunit. (484 aa)
Nham_1119D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (529 aa)
Nham_1118Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (390 aa)
Nham_1112L-lactate dehydrogenase (cytochrome). (381 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (285 aa)
Nham_1103Aminotransferase. (400 aa)
Nham_1097Isocitrate lyase. (435 aa)
Nham_1088Thioesterase superfamily. (154 aa)
Nham_10873-hydroxyacyl-CoA dehydrogenase. (696 aa)
slyXSlyX; Belongs to the SlyX family. (70 aa)
Nham_1057UDP-glucose 6-dehydrogenase. (433 aa)
Nham_0996Glutamate dehydrogenase (NADP); Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (451 aa)
Nham_09843-dehydroquinate synthase. (397 aa)
Nham_0938Short chain enoyl-CoA hydratase / Enoyl-CoA hydratase. (260 aa)
Nham_0937Phenylacetic acid degradation protein PaaD. (149 aa)
Nham_0936phenylacetate-CoA ligase. (105 aa)
Nham_0934Phenylacetic acid degradation protein paaN. (691 aa)
Nham_0933Phenylacetic acid catabolic. (250 aa)
Nham_0931Phenylacetate-CoA oxygenase, PaaJ subunit. (174 aa)
Nham_0930Phenylacetate-CoA oxygenase, PaaI subunit. (283 aa)
Nham_0929Phenylacetic acid degradation B. (94 aa)
Nham_4023Peptidase C26. (256 aa)
Nham_40104-phosphoerythronate dehydrogenase (FAD-dependent). (478 aa)
Nham_3973Amidohydrolase. (409 aa)
Nham_3748propionyl-CoA synthetase. (641 aa)
ispH-24-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (324 aa)
thrBHomoserine kinase; Belongs to the pseudomonas-type ThrB family. (326 aa)
Nham_3734AMP-dependent synthetase and ligase. (560 aa)
argBN-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (298 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (281 aa)
dapESuccinyldiaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (411 aa)
metEMethionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (778 aa)
argGArgininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (409 aa)
Nham_3600AMP-dependent synthetase and ligase. (505 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (370 aa)
asdAspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa)
leuD3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (201 aa)
leuC3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (468 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (290 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (727 aa)
Nham_3548Alcohol dehydrogenase, zinc-binding protein. (332 aa)
Nham_3534Fructose-bisphosphate aldolase. (343 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (398 aa)
Nham_3531Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (678 aa)
Nham_3505Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (937 aa)
Nham_3486glutamyl-tRNA synthetase, class Ic; Belongs to the class-I aminoacyl-tRNA synthetase family. (290 aa)
Nham_3480Electron transfer flavoprotein, alpha subunit. (314 aa)
Nham_34793-hydroxyacyl-CoA dehydrogenase. (293 aa)
argHArgininosuccinate lyase. (465 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (421 aa)
Nham_3398L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1017 aa)
Nham_32706-phosphogluconate dehydrogenase (decarboxylating). (337 aa)
talTransaldolase / glucose-6-phosphate isomerase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family. (950 aa)
Nham_3254Conserved hypothetical protein. (687 aa)
Nham_3238Anthranilate synthase, component I. (730 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (303 aa)
glyQglycyl-tRNA synthetase alpha chain. (314 aa)
glySglycyl-tRNA synthetase beta chain. (764 aa)
Nham_3204FAD linked oxidase-like protein. (497 aa)
Nham_3203FAD linked oxidase-like protein. (452 aa)
hisGATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (325 aa)
Nham_3187ATP phosphoribosyltransferase regulatory subunit. (395 aa)
ileSIsoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). (999 aa)
Nham_3157Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (445 aa)
hisShistidyl-tRNA synthetase. (526 aa)
Nham_3139Branched chain amino acid aminotransferase apoenzyme. (370 aa)
Nham_3126Twin-arginine translocation pathway signal; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (983 aa)
Nham_3111Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (405 aa)
pdhA-2Pyruvate dehydrogenase (lipoamide); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (363 aa)
Nham_3108Transketolase, central region. (326 aa)
Nham_3107Catalytic domain of components of various dehydrogenase complexes. (366 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (278 aa)
Nham_3099MaoC-like dehydratase. (153 aa)
Nham_3098MaoC-like dehydratase. (160 aa)
Nham_3038Transferase hexapeptide repeat. (169 aa)
Nham_2981NapD-like protein. (340 aa)
Nham_2951Hypothetical protein. (172 aa)
Nham_29163-mercaptopyruvate sulfurtransferase. (286 aa)
Nham_2891Glycine oxidase. (338 aa)
carBCarbamoyl-phosphate synthase large subunit; Belongs to the CarB family. (1154 aa)
carACarbamoyl-phosphate synthase small subunit; Belongs to the CarA family. (396 aa)
nadAQuinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (327 aa)
Nham_28168-amino-7-oxononanoate synthase. (377 aa)
bioDDethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (212 aa)
Nham_2814Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (419 aa)
Nham_2804Serine--glyoxylate transaminase. (399 aa)
Nham_2803Hypothetical protein; Belongs to the CoA-transferase III family. (181 aa)
Nham_2755UDP-glucose 6-dehydrogenase. (436 aa)
fumCFumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (471 aa)
Nham_2729Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (178 aa)
Nham_2724Phosphoserine phosphatase. (241 aa)
Nham_2721Acetolactate synthase, small subunit. (180 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (520 aa)
Nham_2706MaoC-like dehydratase. (150 aa)
Nham_2702Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (419 aa)
Nham_2698D-amino-acid dehydrogenase. (433 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (929 aa)
Nham_2680Radical SAM. (389 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (314 aa)
Nham_2676Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (463 aa)
Nham_2664L-threonine ammonia-lyase. (415 aa)
Nham_2663Conserved hypothetical protein. (620 aa)
Nham_2646Nitrous oxidase accessory protein. (455 aa)
Nham_26352-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (163 aa)
Nham_2634Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (121 aa)
Nham_2633Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (294 aa)
Nham_2592Conserved hypothetical protein. (99 aa)
Nham_2579Serine O-acetyltransferase. (273 aa)
Nham_25563-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (299 aa)
Nham_2555AMP-dependent synthetase and ligase. (577 aa)
Nham_2554MaoC-like dehydratase. (159 aa)
guaAGMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (540 aa)
Nham_2458O-acetylhomoserine sulfhydrolase. (425 aa)
Nham_24322,5-didehydrogluconate reductase. (272 aa)
panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (283 aa)
Nham_2354[Acyl-carrier-protein] S-malonyltransferase. (319 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (79 aa)
Nham_23513-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (421 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (418 aa)
anmKProtein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (366 aa)
Nham_2329Aminotransferase, class V. (399 aa)
Nham_2325Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (414 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (332 aa)
Nham_2310Aminotransferase. (405 aa)
Nham_2309Homoserine dehydrogenase. (440 aa)
Nham_2301Lysine--tRNA ligase. (345 aa)
Nham_2300L-lysine 2,3-aminomutase. (366 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (504 aa)
Nham_2290Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (398 aa)
pyrBAspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (317 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (296 aa)
acpSHolo-(acyl-carrier-protein) synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (139 aa)
Nham_0866Enoyl-[acyl-carrier-protein] reductase (NADH). (262 aa)
Nham_0849MaoC-like dehydratase. (153 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (366 aa)
Nham_0769Phosphoglycerate mutase. (197 aa)
Nham_0759AMP-dependent synthetase and ligase. (542 aa)
Nham_0754Beta-lactamase-like protein. (315 aa)
glmSGlutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (608 aa)
Nham_2067Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (346 aa)
Nham_2072Cystathionine beta-lyase. (398 aa)
Nham_2054Protein of unknown function DUF339. (96 aa)
Nham_2051AMP-dependent synthetase and ligase. (501 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. (659 aa)
Nham_2005AMP-dependent synthetase and ligase. (547 aa)
Nham_1875Cys/Met metabolism pyridoxal-phosphate-dependent enzyme. (375 aa)
Nham_1840Branched chain amino acid: 2-keto-4-methylthiobutyrate aminotransferase. (285 aa)
ispDF2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. (419 aa)
lipALipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (319 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (954 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (434 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (470 aa)
Nham_1773Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (325 aa)
argSarginyl-tRNA synthetase. (597 aa)
Nham_1751Dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (454 aa)
Nham_1750Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (474 aa)
pdhAPyruvate dehydrogenase (lipoamide); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (340 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
kdsA2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. (287 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (545 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (337 aa)
trpCIndole-3-glycerol phosphate synthase; Belongs to the TrpC family. (281 aa)
glnSglutaminyl-tRNA synthetase. (558 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (491 aa)
fabZ3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (151 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (407 aa)
panBKetopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (275 aa)
thrSSer-tRNA(Thr) hydrolase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (681 aa)
Nham_0684Cystathionine gamma-synthase. (422 aa)
cysISulfite reductase (NADPH) beta subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (576 aa)
Nham_0682Sulfite reductase (NADPH) alpha subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. (613 aa)
metXAHomoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (399 aa)
Nham_0675Chorismate mutase. (297 aa)
hisCHistidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (365 aa)
Nham_0673Prephenate dehydrogenase. (313 aa)
argFOrnithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (308 aa)
argDAcetylornithine aminotransferase apoenzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (403 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (431 aa)
Nham_0613Amine oxidase. (419 aa)
folD5,10-methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (294 aa)
Nham_0563Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (248 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (652 aa)
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (322 aa)
Nham_05422-oxoglutarate dehydrogenase E1 component. (989 aa)
Nham_05412-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (413 aa)
Nham_0539Hypothetical protein. (53 aa)
proAGlutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (430 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (379 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (383 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (224 aa)
accAacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (320 aa)
argJN-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (426 aa)
Nham_0472Aspartate kinase; Belongs to the aspartokinase family. (417 aa)
gloBHydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (255 aa)
Nham_0447Arginase; Belongs to the arginase family. (325 aa)
Nham_0422Ferredoxin-dependent glutamate synthase; Belongs to the glutamate synthase family. (541 aa)
Nham_0408Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (905 aa)
Nham_0365Prephenate dehydratase. (286 aa)
Nham_03645,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (304 aa)
Nham_0363Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1261 aa)
Nham_03573-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (707 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (431 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (340 aa)
Nham_0262L-threonine synthase. (472 aa)
metZO-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (422 aa)
lysSlysyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (543 aa)
Nham_0186Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (306 aa)
ilvDDihydroxyacid dehydratase; Belongs to the IlvD/Edd family. (613 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (449 aa)
gpmAPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (207 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (289 aa)
hisEphosphoribosyl-ATP pyrophosphatase. (107 aa)
hisFImidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (258 aa)
hisA1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (246 aa)
hisHImidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (216 aa)
hisBImidazoleglycerol-phosphate dehydratase. (197 aa)
leuSleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (878 aa)
Nham_0089Aminotransferase. (423 aa)
pheSphenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (368 aa)
pheTphenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (817 aa)
Nham_0071Twin-arginine translocation pathway signal. (504 aa)
Nham_0068Protein of unknown function DUF540. (246 aa)
trpFPhosphoribosylanthranilate isomerase; Belongs to the TrpF family. (225 aa)
trpBTryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (414 aa)
trpATryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (278 aa)
accDacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (314 aa)
Nham_0060FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. (442 aa)
Nham_0051Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (479 aa)
fabA3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (174 aa)
Nham_00413-oxoacyl-[acyl-carrier-protein] synthase I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (407 aa)
Nham_0040Enoyl-[acyl-carrier-protein] reductase (NADH). (282 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (347 aa)
Nham_2234L-glutamine synthetase. (469 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro); Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily. (439 aa)
Nham_2189acetyl-CoA carboxylase carboxyltransferase subunit alpha; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (451 aa)
Nham_2188Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (162 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (156 aa)
Nham_2183Aminotransferase. (395 aa)
Nham_2180Conserved hypothetical protein. (271 aa)
Nham_2145Glyoxalase/bleomycin resistance protein/dioxygenase. (149 aa)
Nham_2125Propionyl-CoA carboxylase. (547 aa)
aspSaspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (590 aa)
Nham_2110Malate dehydrogenase (oxaloacetate decarboxylating) (NADP+)., Phosphate acetyltransferase. (765 aa)
Nham_2108Conserved hypothetical protein. (183 aa)
Nham_21013-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (180 aa)
Nham_0928Phenylacetate-CoA oxygenase, PaaG subunit. (329 aa)
Nham_0926Fumarylacetoacetate hydrolase. (433 aa)
Nham_0924Monooxygenase, FAD-binding protein. (541 aa)
Nham_0922Beta-lactamase-like protein. (318 aa)
hmgAHomogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (448 aa)
Nham_0920Maleylacetoacetate isomerase. (214 aa)
Nham_0914Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (984 aa)
Nham_0911Pyrophosphate-dependent phosphofructokinase. (407 aa)
Your Current Organism:
Nitrobacter hamburgensis
NCBI taxonomy Id: 323097
Other names: N. hamburgensis X14, Nitrobacter hamburgensis X14, Nitrobacter hamburgensis str. X14, Nitrobacter hamburgensis strain X14
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