STRINGSTRING
fbp fbp gpmI gpmI Noc_0101 Noc_0101 Noc_0111 Noc_0111 Noc_0112 Noc_0112 Noc_0113 Noc_0113 Noc_0244 Noc_0244 Noc_0268 Noc_0268 tal tal Noc_0391 Noc_0391 Noc_0494 Noc_0494 gcvT gcvT prs prs Noc_0603 Noc_0603 sucC sucC sucD sucD ppc ppc zwf zwf Noc_0826 Noc_0826 Noc_0827 Noc_0827 eno eno Noc_0864 Noc_0864 acsA acsA acyP acyP pgi pgi gcvH gcvH gcvPA gcvPA Noc_0965 Noc_0965 Noc_0983 Noc_0983 Noc_0990 Noc_0990 Noc_1254 Noc_1254 Noc_1255 Noc_1255 Noc_1256 Noc_1256 Noc_1267 Noc_1267 pgl pgl Noc_1378 Noc_1378 gpmA gpmA Noc_1433 Noc_1433 Noc_1434 Noc_1434 pdhA pdhA Noc_1446 Noc_1446 Noc_1555 Noc_1555 Noc_1582 Noc_1582 Noc_1583 Noc_1583 Noc_1603 Noc_1603 Noc_1604 Noc_1604 Noc_1608 Noc_1608 fumC fumC Noc_1697 Noc_1697 Noc_1710 Noc_1710 Noc_1719 Noc_1719 Noc_1733 Noc_1733 Noc_1734 Noc_1734 Noc_1735 Noc_1735 Noc_1736 Noc_1736 Noc_1788 Noc_1788 Noc_1888 Noc_1888 Noc_1889 Noc_1889 Noc_1890 Noc_1890 Noc_1891 Noc_1891 Noc_1893 Noc_1893 Noc_2046 Noc_2046 Noc_2047 Noc_2047 Noc_2054 Noc_2054 tal-2 tal-2 Noc_2061 Noc_2061 zwf-2 zwf-2 Noc_2077 Noc_2077 Noc_2103 Noc_2103 Noc_2109 Noc_2109 Noc_2110 Noc_2110 pdhA-2 pdhA-2 Noc_2207 Noc_2207 Noc_2208 Noc_2208 prpB prpB Noc_2280 Noc_2280 Noc_2420 Noc_2420 Noc_2470 Noc_2470 Noc_2471 Noc_2471 Noc_2472 Noc_2472 Noc_2473 Noc_2473 Noc_2492 Noc_2492 Noc_2512 Noc_2512 gcvPB gcvPB tpiA tpiA Noc_2605 Noc_2605 Noc_2628 Noc_2628 Noc_2652 Noc_2652 rpiA rpiA Noc_2707 Noc_2707 ackA ackA Noc_2717 Noc_2717 mdh mdh Noc_2804 Noc_2804 Noc_2805 Noc_2805 pgk pgk Noc_2807 Noc_2807 Noc_2808 Noc_2808 pfp pfp Noc_2916 Noc_2916 Noc_2957 Noc_2957 Noc_2978 Noc_2978 Noc_2994 Noc_2994
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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gene neighborhood
gene fusions
gene co-occurrence
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textmining
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Your Input:
fbpD-fructose 1,6-bisphosphatase. (335 aa)
gpmIPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (517 aa)
Noc_0101Ferredoxin-dependent glutamate synthase; Belongs to the glutamate synthase family. (551 aa)
Noc_01112-oxoglutarate dehydrogenase E1 component. (940 aa)
Noc_01122-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (435 aa)
Noc_0113Dihydrolipoamide dehydrogenase. (480 aa)
Noc_0244Malate dehydrogenase (oxaloacetate decarboxylating) (NADP+). (401 aa)
Noc_0268Transketolase. (606 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (376 aa)
Noc_0391Aldehyde dehydrogenase. (454 aa)
Noc_0494Kinase-like protein. (371 aa)
gcvTGlycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (371 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (336 aa)
Noc_0603Thioredoxin domain-containing protein. (287 aa)
sucCsuccinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa)
sucDsuccinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (291 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (957 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (490 aa)
Noc_0826Short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (672 aa)
Noc_08273-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (434 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (426 aa)
Noc_0864Glutamate dehydrogenase (NADP); Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (448 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (657 aa)
acyPAcylphosphatase. (89 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (549 aa)
gcvHGlycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (130 aa)
gcvPAGlycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (452 aa)
Noc_0965Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) component-like enzyme. (467 aa)
Noc_0983Ribose-phosphate pyrophosphokinase. (332 aa)
Noc_0990Pyruvate kinase; Belongs to the pyruvate kinase family. (492 aa)
Noc_12542-oxo-acid dehydrogenase E1 component homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (891 aa)
Noc_1255Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) component-like enzyme. (447 aa)
Noc_1256Dihydrolipoamide dehydrogenase. (472 aa)
Noc_1267Hypothetical protein. (266 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (242 aa)
Noc_1378Isocitrate dehydrogenase (NADP). (422 aa)
gpmAPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (240 aa)
Noc_1433Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) component-like enzyme. (374 aa)
Noc_1434Transketolase. (326 aa)
pdhAPyruvate dehydrogenase (lipoamide); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (358 aa)
Noc_1446Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (794 aa)
Noc_1555Acyl-CoA dehydrogenase. (639 aa)
Noc_1582Allosteric NADP-dependent malic enzyme; Phosphate acetyltransferase. (783 aa)
Noc_1583Conserved hypothetical protein. (1170 aa)
Noc_1603Glutamate synthase (NADH) small subunit. (480 aa)
Noc_1604Glutamate synthase (NADH) large subunit. (1554 aa)
Noc_1608NADPH-glutathione reductase; Maintains high levels of reduced glutathione. (452 aa)
fumCFumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (468 aa)
Noc_1697Carbohydrate kinase, FGGY. (426 aa)
Noc_1710Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (513 aa)
Noc_1719Phosphoglucomutase/phosphomannomutase. (563 aa)
Noc_1733Short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (744 aa)
Noc_17343-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (430 aa)
Noc_1735Acyl-CoA dehydrogenase-like protein. (781 aa)
Noc_1736Conserved hypothetical protein. (728 aa)
Noc_1788Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (907 aa)
Noc_1888hydroxymethylglutaryl-CoA lyase. (306 aa)
Noc_1889Enoyl-CoA hydratase/isomerase. (261 aa)
Noc_1890Propionyl-CoA carboxylase. (535 aa)
Noc_1891Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
Noc_1893Methylmalonyl-CoA mutase-like protein. (1139 aa)
Noc_2046Zinc-containing alcohol dehydrogenase superfamily. (333 aa)
Noc_2047Acetoacetyl-CoA synthase. (651 aa)
Noc_2054Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (419 aa)
tal-2Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (376 aa)
Noc_20616-phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (481 aa)
zwf-2Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (507 aa)
Noc_20776-phosphogluconate dehydrogenase, NAD-binding protein. (285 aa)
Noc_2103Aconitase; Belongs to the aconitase/IPM isomerase family. (850 aa)
Noc_2109Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) component-like enzyme. (902 aa)
Noc_2110Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (326 aa)
pdhA-2Dehydrogenase, E1 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (339 aa)
Noc_22072-methylcitrate dehydratase. (483 aa)
Noc_22082-methylcitrate synthase; Belongs to the citrate synthase family. (374 aa)
prpBMethylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (294 aa)
Noc_2280UDP-glucose pyrophosphorylase. (297 aa)
Noc_2420NUDIX hydrolase. (184 aa)
Noc_2470Succinate dehydrogenase subunit B. (231 aa)
Noc_2471Succinate dehydrogenase subunit A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (587 aa)
Noc_2472Succinate dehydrogenase subunit D. (105 aa)
Noc_2473Succinate dehydrogenase subunit C. (140 aa)
Noc_2492Ribulose-5-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (223 aa)
Noc_2512NUDIX hydrolase; Belongs to the Nudix hydrolase family. (172 aa)
gcvPBGlycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (486 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa)
Noc_2605Aldehyde dehydrogenase (acceptor). (494 aa)
Noc_2628Citrate synthase; Belongs to the citrate synthase family. (387 aa)
Noc_2652L-glutamine synthetase. (469 aa)
rpiARibose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (220 aa)
Noc_2707Aconitase. (660 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (408 aa)
Noc_2717Fructose-6-phosphate phosphoketolase. (804 aa)
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (311 aa)
Noc_2804Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa)
Noc_2805Pyruvate kinase; Belongs to the pyruvate kinase family. (483 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (392 aa)
Noc_2807Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (337 aa)
Noc_2808Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (665 aa)
pfpPyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (421 aa)
Noc_2916Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (519 aa)
Noc_2957Ferredoxin-dependent glutamate synthase; Belongs to the glutamate synthase family. (510 aa)
Noc_2978Glutamate dehydrogenase (NAD). (1594 aa)
Noc_2994Phosphomannomutase. (468 aa)
Your Current Organism:
Nitrosococcus oceani
NCBI taxonomy Id: 323261
Other names: N. oceani ATCC 19707, Nitrosococcus oceani ATCC 19707, Nitrosococcus oceani C-107, Nitrosococcus oceani NCIMB 11848, Nitrosococcus oceani str. ATCC 19707, Nitrosococcus oceani strain ATCC 19707
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