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Noc_0101 Noc_0101 Noc_0111 Noc_0111 Noc_0112 Noc_0112 Noc_0113 Noc_0113 Noc_0244 Noc_0244 Noc_0391 Noc_0391 gcvT gcvT Noc_0603 Noc_0603 sucC sucC sucD sucD Noc_0826 Noc_0826 Noc_0827 Noc_0827 Noc_0864 Noc_0864 acsA acsA acyP acyP gcvH gcvH gcvPA gcvPA Noc_0965 Noc_0965 Noc_1254 Noc_1254 Noc_1255 Noc_1255 Noc_1256 Noc_1256 Noc_1267 Noc_1267 Noc_1378 Noc_1378 Noc_1433 Noc_1433 Noc_1434 Noc_1434 pdhA pdhA Noc_1555 Noc_1555 Noc_1582 Noc_1582 Noc_1583 Noc_1583 Noc_1603 Noc_1603 Noc_1604 Noc_1604 Noc_1608 Noc_1608 fumC fumC Noc_1710 Noc_1710 Noc_1733 Noc_1733 Noc_1734 Noc_1734 Noc_1735 Noc_1735 Noc_1736 Noc_1736 Noc_1788 Noc_1788 Noc_1888 Noc_1888 Noc_1889 Noc_1889 Noc_1890 Noc_1890 Noc_1891 Noc_1891 Noc_1893 Noc_1893 Noc_2046 Noc_2046 Noc_2047 Noc_2047 Noc_2054 Noc_2054 Noc_2077 Noc_2077 Noc_2103 Noc_2103 Noc_2109 Noc_2109 Noc_2110 Noc_2110 pdhA-2 pdhA-2 Noc_2207 Noc_2207 Noc_2208 Noc_2208 prpB prpB Noc_2470 Noc_2470 Noc_2471 Noc_2471 Noc_2472 Noc_2472 Noc_2473 Noc_2473 gcvPB gcvPB Noc_2605 Noc_2605 Noc_2628 Noc_2628 Noc_2652 Noc_2652 Noc_2707 Noc_2707 mdh mdh Noc_2916 Noc_2916 Noc_2957 Noc_2957 Noc_2978 Noc_2978
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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gene neighborhood
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Noc_0101Ferredoxin-dependent glutamate synthase; Belongs to the glutamate synthase family. (551 aa)
Noc_01112-oxoglutarate dehydrogenase E1 component. (940 aa)
Noc_01122-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (435 aa)
Noc_0113Dihydrolipoamide dehydrogenase. (480 aa)
Noc_0244Malate dehydrogenase (oxaloacetate decarboxylating) (NADP+). (401 aa)
Noc_0391Aldehyde dehydrogenase. (454 aa)
gcvTGlycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (371 aa)
Noc_0603Thioredoxin domain-containing protein. (287 aa)
sucCsuccinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa)
sucDsuccinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (291 aa)
Noc_0826Short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (672 aa)
Noc_08273-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (434 aa)
Noc_0864Glutamate dehydrogenase (NADP); Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (448 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (657 aa)
acyPAcylphosphatase. (89 aa)
gcvHGlycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (130 aa)
gcvPAGlycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (452 aa)
Noc_0965Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) component-like enzyme. (467 aa)
Noc_12542-oxo-acid dehydrogenase E1 component homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (891 aa)
Noc_1255Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) component-like enzyme. (447 aa)
Noc_1256Dihydrolipoamide dehydrogenase. (472 aa)
Noc_1267Hypothetical protein. (266 aa)
Noc_1378Isocitrate dehydrogenase (NADP). (422 aa)
Noc_1433Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) component-like enzyme. (374 aa)
Noc_1434Transketolase. (326 aa)
pdhAPyruvate dehydrogenase (lipoamide); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (358 aa)
Noc_1555Acyl-CoA dehydrogenase. (639 aa)
Noc_1582Allosteric NADP-dependent malic enzyme; Phosphate acetyltransferase. (783 aa)
Noc_1583Conserved hypothetical protein. (1170 aa)
Noc_1603Glutamate synthase (NADH) small subunit. (480 aa)
Noc_1604Glutamate synthase (NADH) large subunit. (1554 aa)
Noc_1608NADPH-glutathione reductase; Maintains high levels of reduced glutathione. (452 aa)
fumCFumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (468 aa)
Noc_1710Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (513 aa)
Noc_1733Short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (744 aa)
Noc_17343-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (430 aa)
Noc_1735Acyl-CoA dehydrogenase-like protein. (781 aa)
Noc_1736Conserved hypothetical protein. (728 aa)
Noc_1788Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (907 aa)
Noc_1888hydroxymethylglutaryl-CoA lyase. (306 aa)
Noc_1889Enoyl-CoA hydratase/isomerase. (261 aa)
Noc_1890Propionyl-CoA carboxylase. (535 aa)
Noc_1891Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
Noc_1893Methylmalonyl-CoA mutase-like protein. (1139 aa)
Noc_2046Zinc-containing alcohol dehydrogenase superfamily. (333 aa)
Noc_2047Acetoacetyl-CoA synthase. (651 aa)
Noc_2054Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (419 aa)
Noc_20776-phosphogluconate dehydrogenase, NAD-binding protein. (285 aa)
Noc_2103Aconitase; Belongs to the aconitase/IPM isomerase family. (850 aa)
Noc_2109Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) component-like enzyme. (902 aa)
Noc_2110Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (326 aa)
pdhA-2Dehydrogenase, E1 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (339 aa)
Noc_22072-methylcitrate dehydratase. (483 aa)
Noc_22082-methylcitrate synthase; Belongs to the citrate synthase family. (374 aa)
prpBMethylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (294 aa)
Noc_2470Succinate dehydrogenase subunit B. (231 aa)
Noc_2471Succinate dehydrogenase subunit A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (587 aa)
Noc_2472Succinate dehydrogenase subunit D. (105 aa)
Noc_2473Succinate dehydrogenase subunit C. (140 aa)
gcvPBGlycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (486 aa)
Noc_2605Aldehyde dehydrogenase (acceptor). (494 aa)
Noc_2628Citrate synthase; Belongs to the citrate synthase family. (387 aa)
Noc_2652L-glutamine synthetase. (469 aa)
Noc_2707Aconitase. (660 aa)
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (311 aa)
Noc_2916Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (519 aa)
Noc_2957Ferredoxin-dependent glutamate synthase; Belongs to the glutamate synthase family. (510 aa)
Noc_2978Glutamate dehydrogenase (NAD). (1594 aa)
Your Current Organism:
Nitrosococcus oceani
NCBI taxonomy Id: 323261
Other names: N. oceani ATCC 19707, Nitrosococcus oceani ATCC 19707, Nitrosococcus oceani C-107, Nitrosococcus oceani NCIMB 11848, Nitrosococcus oceani str. ATCC 19707, Nitrosococcus oceani strain ATCC 19707
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