STRINGSTRING
aroE aroE leuB leuB Noc_1078 Noc_1078 Noc_1079 Noc_1079 Noc_1378 Noc_1378 Noc_1394 Noc_1394 Noc_1582 Noc_1582 pdxA pdxA Noc_1733 Noc_1733 Noc_2015 Noc_2015 Noc_1927 Noc_1927 Noc_2025 Noc_2025 Noc_2032 Noc_2032 Noc_2061 Noc_2061 zwf-2 zwf-2 Noc_2131 Noc_2131 Noc_2454 Noc_2454 ilvC ilvC gpsA gpsA Noc_0173 Noc_0173 Noc_0244 Noc_0244 zwf zwf Noc_0776 Noc_0776 dxr dxr Noc_0826 Noc_0826 murB murB mdh mdh hisD hisD Noc_2637 Noc_2637
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (282 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. (362 aa)
Noc_1078Putative dehydrogenase. (343 aa)
Noc_1079Bifunctional deaminase-reductase-like protein. (364 aa)
Noc_1378Isocitrate dehydrogenase (NADP). (422 aa)
Noc_1394Zinc-containing alcohol dehydrogenase superfamily; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (370 aa)
Noc_1582Allosteric NADP-dependent malic enzyme; Phosphate acetyltransferase. (783 aa)
pdxA4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (331 aa)
Noc_1733Short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (744 aa)
Noc_2015UDP-glucose 6-dehydrogenase. (463 aa)
Noc_1927Conserved hypothetical protein. (253 aa)
Noc_20255-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (365 aa)
Noc_2032D-isomer specific 2-hydroxyacid dehydrogenase. (318 aa)
Noc_20616-phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (481 aa)
zwf-2Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (507 aa)
Noc_2131Pyrimidine reductase, riboflavin biosynthesis, RibD. (291 aa)
Noc_2454Homoserine dehydrogenase. (436 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa)
gpsAGlycerol 3-phosphate dehydrogenase (NAD(P)+); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (344 aa)
Noc_0173D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (387 aa)
Noc_0244Malate dehydrogenase (oxaloacetate decarboxylating) (NADP+). (401 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (490 aa)
Noc_0776dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (295 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (393 aa)
Noc_0826Short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (672 aa)
murBUDP-N-acetylmuramate dehydrogenase; Cell wall formation. (298 aa)
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (311 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (433 aa)
Noc_2637UDP-glucose/GDP-mannose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (425 aa)
Your Current Organism:
Nitrosococcus oceani
NCBI taxonomy Id: 323261
Other names: N. oceani ATCC 19707, Nitrosococcus oceani ATCC 19707, Nitrosococcus oceani C-107, Nitrosococcus oceani NCIMB 11848, Nitrosococcus oceani str. ATCC 19707, Nitrosococcus oceani strain ATCC 19707
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