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polA polA Shew_0050 Shew_0050 orn orn Shew_1143 Shew_1143 rnt rnt Shew_1611 Shew_1611 Shew_1682 Shew_1682 Shew_1871 Shew_1871 ruvC ruvC dnaQ dnaQ rnhA rnhA rnd rnd Shew_2368 Shew_2368 Shew_2482 Shew_2482 rnhB rnhB Shew_3634 Shew_3634 Shew_3827 Shew_3827 Shew_3830 Shew_3830
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (930 aa)
Shew_0050PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: ppr:PBPRA2517 putative DNA polymerase III, epsilon subunit. (239 aa)
ornExonuclease, RNase T and DNA polymerase III; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family. (181 aa)
Shew_1143Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (139 aa)
rntRNAse T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. (257 aa)
Shew_1611PFAM: Exonuclease, RNase T and DNA polymerase III; Exonuclease C-terminal domain protein; KEGG: son:SO2790 exodeoxyribonuclease I. (482 aa)
Shew_1682Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (254 aa)
Shew_1871KEGG: vfi:VFA0016 DNA polymerase III epsilon subunit (3'-5' exonuclease); TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease. (204 aa)
ruvCCrossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (173 aa)
dnaQDNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (242 aa)
rnhARibonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (158 aa)
rndRibonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. (368 aa)
Shew_2368PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: she:Shewmr4_1516 exonuclease, RNase T and DNA polymerase III. (226 aa)
Shew_2482PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: she:Shewmr4_2469 DNA polymerase B region. (795 aa)
rnhBRNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (208 aa)
Shew_3634PFAM: RNA binding S1 domain protein; SMART: Resolvase, RNase H domain protein fold; KEGG: son:SO4629 hypothetical protein. (787 aa)
Shew_3827KEGG: ilo:IL2612 transposon Tn7 transposition protein TnsB. (696 aa)
Shew_3830PFAM: Integrase, catalytic region; KEGG: vch:VCA0791 transposase OrfAB, subunit B. (244 aa)
Your Current Organism:
Shewanella loihica
NCBI taxonomy Id: 323850
Other names: S. loihica PV-4, Shewanella loihica PV-4, Shewanella loihica str. PV-4, Shewanella loihica strain PV-4, Shewanella sp. PV-4
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