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Caur_3544 Caur_3544 Caur_3546 Caur_3546 Caur_3547 Caur_3547 mnmA mnmA sat sat Caur_0440 Caur_0440 Caur_0691 Caur_0691 Caur_0714 Caur_0714 cysS cysS guaA guaA nadE nadE trpS trpS gltX gltX cysS-2 cysS-2 argS argS tilS tilS sat-2 sat-2 Caur_2177 Caur_2177 panC panC nadD nadD coaD coaD Caur_2527 Caur_2527 valS valS Caur_2690 Caur_2690 ileS ileS leuS leuS Caur_2922 Caur_2922 Caur_2955 Caur_2955 tyrS tyrS metG metG Caur_3505 Caur_3505
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
Caur_3544PFAM: argininosuccinate synthase; KEGG: bmn:BMA10247_2224 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (449 aa)
Caur_3546PFAM: Electron transfer flavoprotein alpha/beta-subunit; KEGG: rrs:RoseRS_2299 electron transfer flavoprotein beta-subunit. (259 aa)
Caur_3547PFAM: Electron transfer flavoprotein alpha/beta-subunit; Electron transfer flavoprotein alpha subunit; KEGG: rrs:RoseRS_2298 electron transfer flavoprotein, alpha subunit. (325 aa)
mnmAtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (359 aa)
satKEGG: dge:Dgeo_1410 sulfate adenylyltransferase; TIGRFAM: sulfate adenylyltransferase; PFAM: ATP-sulfurylase; Belongs to the sulfate adenylyltransferase family. (381 aa)
Caur_0440PFAM: deoxyribodipyrimidine photolyase-related protein; KEGG: rrs:RoseRS_0009 deoxyribodipyrimidine photolyase-related protein. (497 aa)
Caur_0691Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. (221 aa)
Caur_0714Deoxyribodipyrimidine photo-lyase; PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein; KEGG: sru:SRU_2330 deoxyribodipyrimidine photolyase, putative. (510 aa)
cysSKEGG: rrs:RoseRS_3331 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. (398 aa)
guaAGMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (513 aa)
nadENAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (697 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (336 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (503 aa)
cysS-2KEGG: rca:Rcas_2138 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. (472 aa)
argSKEGG: rca:Rcas_1644 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. (574 aa)
tilStRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (474 aa)
sat-2Sulfate adenylyltransferase; Catalyzes the synthesis of activated sulfate. Belongs to the sulfate adenylyltransferase family. (569 aa)
Caur_2177TIGRFAM: cytidyltransferase-related domain protein; PFAM: cytidylyltransferase; KEGG: plt:Plut_1901 RfaE bifunctional protein, domain II. (176 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (281 aa)
nadDNicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (205 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (161 aa)
Caur_2527PFAM: UspA domain protein; KEGG: rca:Rcas_3776 UspA domain protein. (290 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (923 aa)
Caur_2690PFAM: UspA domain protein; KEGG: deb:DehaBAV1_1111 UspA domain protein. (153 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1066 aa)
leuSTIGRFAM: leucyl-tRNA synthetase; KEGG: lme:LEUM_0635 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1000 aa)
Caur_2922KEGG: rca:Rcas_2072 hypothetical protein. (206 aa)
Caur_2955TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: cytidylyltransferase; FAD synthetase; Riboflavin kinase; KEGG: rca:Rcas_1127 riboflavin biosynthesis protein RibF; Belongs to the ribF family. (311 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (390 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (600 aa)
Caur_3505Deoxyribodipyrimidine photo-lyase; PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein; KEGG: rca:Rcas_4411 deoxyribodipyrimidine photo-lyase. (479 aa)
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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