(22 nodes) Mixed, incl. DOCK N-terminus, and ELMO, armadillo-like helical domain network (Xiphophorus couchianus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSXCOP00000000336	Uncharacterized protein; Belongs to the DOCK family. (1835 aa)
	ENSXCOP00000001260	Uncharacterized protein. (301 aa)
	ENSXCOP00000001764	Rap guanine nucleotide exchange factor (GEF) 1b. (1048 aa)
	DOCK2	Dedicator of cytokinesis 2; Belongs to the DOCK family. (1768 aa)
	Abl1	Protein kinase domain-containing protein. (223 aa)
	CRK	CRK proto-oncogene, adaptor protein. (315 aa)
	crkl	V-crk avian sarcoma virus CT10 oncogene homolog-like. (299 aa)
	ENSXCOP00000007202	BCAR1 scaffold protein, Cas family member. (897 aa)
	ENSXCOP00000007261	DHR-1 domain-containing protein; Belongs to the DOCK family. (441 aa)
	ENSXCOP00000007274	Dedicator of cytokinesis 1; Belongs to the DOCK family. (1047 aa)
	ENSXCOP00000007578	Engulfment and cell motility 3. (442 aa)
	ENSXCOP00000008173	Uncharacterized protein. (89 aa)
	Rhoq	Ras homolog family member Q. (148 aa)
	ENSXCOP00000011492	Uncharacterized protein. (111 aa)
	ENSXCOP00000011828	Ras homolog gene family, member Gd. (101 aa)
	Abl2	Tyrosine-protein kinase. (1177 aa)
	ENSXCOP00000018512	Uncharacterized protein; Belongs to the DOCK family. (1914 aa)
	Dock5	Dedicator of cytokinesis 5; Belongs to the DOCK family. (1836 aa)
	ENSXCOP00000021701	Uncharacterized protein. (3061 aa)
	ENSXCOP00000024722	Engulfment and cell motility 2. (667 aa)
	ENSXCOP00000024803	Ras homolog family member Gb. (207 aa)
	elmo1	Engulfment and cell motility 1. (726 aa)

Your Current Organism:

Xiphophorus couchianus

NCBI taxonomy Id: 32473
Other names: Limia couchiana, Monterrey platyfish, X. couchianus

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Abl1	Abl2	ENSXCOP00000003743	ENSXCOP00000014316	Protein kinase domain-containing protein.	Tyrosine-protein kinase.	0.912
Abl1	CRK	ENSXCOP00000003743	ENSXCOP00000005850	Protein kinase domain-containing protein.	CRK proto-oncogene, adaptor protein.	0.970
Abl1	ENSXCOP00000001260	ENSXCOP00000003743	ENSXCOP00000001260	Protein kinase domain-containing protein.	Uncharacterized protein.	0.416
Abl1	ENSXCOP00000011492	ENSXCOP00000003743	ENSXCOP00000011492	Protein kinase domain-containing protein.	Uncharacterized protein.	0.414
Abl1	ENSXCOP00000011828	ENSXCOP00000003743	ENSXCOP00000011828	Protein kinase domain-containing protein.	Ras homolog gene family, member Gd.	0.414
Abl1	ENSXCOP00000024803	ENSXCOP00000003743	ENSXCOP00000024803	Protein kinase domain-containing protein.	Ras homolog family member Gb.	0.414
Abl1	crkl	ENSXCOP00000003743	ENSXCOP00000006931	Protein kinase domain-containing protein.	V-crk avian sarcoma virus CT10 oncogene homolog-like.	0.970
Abl2	Abl1	ENSXCOP00000014316	ENSXCOP00000003743	Tyrosine-protein kinase.	Protein kinase domain-containing protein.	0.912
Abl2	CRK	ENSXCOP00000014316	ENSXCOP00000005850	Tyrosine-protein kinase.	CRK proto-oncogene, adaptor protein.	0.970
Abl2	ENSXCOP00000001260	ENSXCOP00000014316	ENSXCOP00000001260	Tyrosine-protein kinase.	Uncharacterized protein.	0.416
Abl2	ENSXCOP00000011492	ENSXCOP00000014316	ENSXCOP00000011492	Tyrosine-protein kinase.	Uncharacterized protein.	0.414
Abl2	ENSXCOP00000011828	ENSXCOP00000014316	ENSXCOP00000011828	Tyrosine-protein kinase.	Ras homolog gene family, member Gd.	0.414
Abl2	ENSXCOP00000024803	ENSXCOP00000014316	ENSXCOP00000024803	Tyrosine-protein kinase.	Ras homolog family member Gb.	0.414
Abl2	crkl	ENSXCOP00000014316	ENSXCOP00000006931	Tyrosine-protein kinase.	V-crk avian sarcoma virus CT10 oncogene homolog-like.	0.970
CRK	Abl1	ENSXCOP00000005850	ENSXCOP00000003743	CRK proto-oncogene, adaptor protein.	Protein kinase domain-containing protein.	0.970
CRK	Abl2	ENSXCOP00000005850	ENSXCOP00000014316	CRK proto-oncogene, adaptor protein.	Tyrosine-protein kinase.	0.970
CRK	DOCK2	ENSXCOP00000005850	ENSXCOP00000002935	CRK proto-oncogene, adaptor protein.	Dedicator of cytokinesis 2; Belongs to the DOCK family.	0.781
CRK	Dock5	ENSXCOP00000005850	ENSXCOP00000020377	CRK proto-oncogene, adaptor protein.	Dedicator of cytokinesis 5; Belongs to the DOCK family.	0.781
CRK	ENSXCOP00000000336	ENSXCOP00000005850	ENSXCOP00000000336	CRK proto-oncogene, adaptor protein.	Uncharacterized protein; Belongs to the DOCK family.	0.778
CRK	ENSXCOP00000001260	ENSXCOP00000005850	ENSXCOP00000001260	CRK proto-oncogene, adaptor protein.	Uncharacterized protein.	0.401