(61 nodes) Negative regulation of cell-cell adhesion network (Xiphophorus couchianus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Nf2	Neurofibromin 2a (merlin). (599 aa)
	Abl2	Tyrosine-protein kinase. (1177 aa)
	LOC114154825	SCY domain-containing protein. (95 aa)
	CD9	Tetraspanin. (223 aa)
	ENSXCOP00000016743	Uncharacterized protein. (266 aa)
	ENSXCOP00000016780	Bone morphogenetic protein 16. (423 aa)
	ENSXCOP00000016993	Core-binding factor subunit beta. (76 aa)
	Cbfb	Core-binding factor subunit beta. (174 aa)
	ENSXCOP00000017395	Galectin. (270 aa)
	Pawr	PRKC, apoptosis, WT1, regulator. (235 aa)
	ENSXCOP00000019099	CCAAT enhancer binding protein beta. (286 aa)
	ENSXCOP00000021252	C1q and TNF related 6b. (238 aa)
	ENSXCOP00000021448	Mitotic arrest deficient 1 like 1. (313 aa)
	ENSXCOP00000022610	Uncharacterized protein. (103 aa)
	Mbp	Myelin basic protein b. (98 aa)
	ENSXCOP00000023215	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (196 aa)
	LOC114149689	C2H2-type domain-containing protein. (588 aa)
	Rgcc	Regulator of cell cycle. (102 aa)
	Vtcn1	V-set domain containing T cell activation inhibitor 1. (233 aa)
	ENSXCOP00000024537	Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (402 aa)
	Lrrc32	Leucine rich repeat containing 32. (626 aa)
	ENSXCOP00000025671	Fibrinogen C-terminal domain-containing protein. (194 aa)
	ENSXCOP00000025796	Uncharacterized protein. (454 aa)
	LOC114146526	Si:dkeyp-66d1.7. (293 aa)
	ENSXCOP00000026707	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (627 aa)
	Ripor2	RHO family interacting cell polarization regulator 2. (1099 aa)
	LOC114159921	Tetraspanin. (233 aa)
	ENSXCOP00000016328	IRF tryptophan pentad repeat domain-containing protein. (256 aa)
	ENSXCOP00000004433	V-set immunoregulatory receptor. (274 aa)
	tbx21	T-box transcription factor 21. (610 aa)
	Nexmif	Neurite extension and migration factor b. (1267 aa)
	arg2	Arginase. (346 aa)
	Serpine2	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family. (401 aa)
	ENSXCOP00000006127	Si:ch211-203k16.3. (343 aa)
	ENSXCOP00000006404	YTH N(6)-methyladenosine RNA binding protein 2. (588 aa)
	ENSXCOP00000006466	Ring finger and CCCH-type domains 2. (1007 aa)
	ENSXCOP00000006537	Uncharacterized protein. (414 aa)
	ENSXCOP00000006938	Uncharacterized protein. (246 aa)
	ENSXCOP00000007881	Si:dkey-40g16.6. (236 aa)
	ENSXCOP00000007914	Amino_oxidase domain-containing protein. (245 aa)
	LOC114157171	Uncharacterized protein. (282 aa)
	ENSXCOP00000009128	Suppressor of cytokine signaling 6a. (459 aa)
	ENSXCOP00000009532	Uncharacterized protein. (409 aa)
	ENSXCOP00000009599	Glomulin, FKBP associated protein a. (579 aa)
	ENSXCOP00000011260	SH2B adaptor protein 3. (307 aa)
	ENSXCOP00000011871	Zinc finger CCCH-type containing 12A. (547 aa)
	ENSXCOP00000012034	Uncharacterized protein. (513 aa)
	znf703	Zinc finger protein 703. (579 aa)
	ENSXCOP00000012951	Neurofibromin 2b (merlin). (567 aa)
	ENSXCOP00000012982	Transforming growth factor beta; Belongs to the TGF-beta family. (389 aa)
	ENSXCOP00000003877	Si:dkey-23c22.7. (212 aa)
	Abl1	Protein kinase domain-containing protein. (223 aa)
	ENSXCOP00000002563	Uncharacterized protein. (285 aa)
	Rc3h1	Ring finger and CCCH-type domains 1b. (1062 aa)
	ENSXCOP00000002560	MARVEL domain-containing protein. (292 aa)
	ENSXCOP00000002179	Membrane-associated ring finger (C3HC4) 7. (690 aa)
	ENSXCOP00000001032	Tumor necrosis factor receptor superfamily, member 21. (609 aa)
	Bmp4	Bone morphogenetic protein 4. (387 aa)
	ENSXCOP00000000330	RIPOR family member 3. (781 aa)
	ENSXCOP00000000010	Itchy E3 ubiquitin protein ligase b. (714 aa)
	ENSXCOP00000004271	Arginase. (342 aa)

Your Current Organism:

Xiphophorus couchianus

NCBI taxonomy Id: 32473
Other names: Limia couchiana, Monterrey platyfish, X. couchianus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Abl1	Abl2	ENSXCOP00000003743	ENSXCOP00000014316	Protein kinase domain-containing protein.	Tyrosine-protein kinase.	0.912
Abl1	Cbfb	ENSXCOP00000003743	ENSXCOP00000016995	Protein kinase domain-containing protein.	Core-binding factor subunit beta.	0.461
Abl1	ENSXCOP00000016993	ENSXCOP00000003743	ENSXCOP00000016993	Protein kinase domain-containing protein.	Core-binding factor subunit beta.	0.461
Abl2	Abl1	ENSXCOP00000014316	ENSXCOP00000003743	Tyrosine-protein kinase.	Protein kinase domain-containing protein.	0.912
Abl2	Cbfb	ENSXCOP00000014316	ENSXCOP00000016995	Tyrosine-protein kinase.	Core-binding factor subunit beta.	0.461
Abl2	ENSXCOP00000016993	ENSXCOP00000014316	ENSXCOP00000016993	Tyrosine-protein kinase.	Core-binding factor subunit beta.	0.461
Cbfb	Abl1	ENSXCOP00000016995	ENSXCOP00000003743	Core-binding factor subunit beta.	Protein kinase domain-containing protein.	0.461
Cbfb	Abl2	ENSXCOP00000016995	ENSXCOP00000014316	Core-binding factor subunit beta.	Tyrosine-protein kinase.	0.461
Cbfb	ENSXCOP00000019099	ENSXCOP00000016995	ENSXCOP00000019099	Core-binding factor subunit beta.	CCAAT enhancer binding protein beta.	0.575
ENSXCOP00000004271	arg2	ENSXCOP00000004271	ENSXCOP00000005640	Arginase.	Arginase.	0.902
ENSXCOP00000006466	Rc3h1	ENSXCOP00000006466	ENSXCOP00000002562	Ring finger and CCCH-type domains 2.	Ring finger and CCCH-type domains 1b.	0.646
ENSXCOP00000006537	ENSXCOP00000012982	ENSXCOP00000006537	ENSXCOP00000012982	Uncharacterized protein.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.418
ENSXCOP00000006537	ENSXCOP00000017395	ENSXCOP00000006537	ENSXCOP00000017395	Uncharacterized protein.	Galectin.	0.516
ENSXCOP00000006537	ENSXCOP00000025796	ENSXCOP00000006537	ENSXCOP00000025796	Uncharacterized protein.	Uncharacterized protein.	0.654
ENSXCOP00000007881	ENSXCOP00000007914	ENSXCOP00000007881	ENSXCOP00000007914	Si:dkey-40g16.6.	Amino_oxidase domain-containing protein.	0.754
ENSXCOP00000007914	ENSXCOP00000007881	ENSXCOP00000007914	ENSXCOP00000007881	Amino_oxidase domain-containing protein.	Si:dkey-40g16.6.	0.754
ENSXCOP00000009599	ENSXCOP00000026707	ENSXCOP00000009599	ENSXCOP00000026707	Glomulin, FKBP associated protein a.	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.	0.810
ENSXCOP00000011871	Rc3h1	ENSXCOP00000011871	ENSXCOP00000002562	Zinc finger CCCH-type containing 12A.	Ring finger and CCCH-type domains 1b.	0.534
ENSXCOP00000012034	ENSXCOP00000012982	ENSXCOP00000012034	ENSXCOP00000012982	Uncharacterized protein.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.870
ENSXCOP00000012951	Nf2	ENSXCOP00000012951	ENSXCOP00000013258	Neurofibromin 2b (merlin).	Neurofibromin 2a (merlin).	0.901