STRINGSTRING
ENSXCOP00000022149 ENSXCOP00000022149 rpa2 rpa2 LOC114138536 LOC114138536 Cul4a Cul4a Dtl Dtl ENSXCOP00000003814 ENSXCOP00000003814 Rpa3 Rpa3 LOC114138068 LOC114138068 ENSXCOP00000004968 ENSXCOP00000004968 pcna pcna uba52 uba52 Rfc4 Rfc4 LOC114133261 LOC114133261 ENSXCOP00000008359 ENSXCOP00000008359 ENSXCOP00000010388 ENSXCOP00000010388 ENSXCOP00000013093 ENSXCOP00000013093 Rfc3 Rfc3 ENSXCOP00000013308 ENSXCOP00000013308 ENSXCOP00000014165 ENSXCOP00000014165 Pole4 Pole4 Pold4 Pold4 Wdr48 Wdr48 ENSXCOP00000018217 ENSXCOP00000018217 ENSXCOP00000018218 ENSXCOP00000018218 Ddb1 Ddb1 rbx1 rbx1 Pold2 Pold2 rfc2 rfc2 Pole Pole LOC114149001 LOC114149001 Pold1 Pold1 ENSXCOP00000024658 ENSXCOP00000024658 RCBTB1 RCBTB1 ENSXCOP00000026621 ENSXCOP00000026621 ENSXCOP00000026801 ENSXCOP00000026801 ENSXCOP00000027383 ENSXCOP00000027383
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSXCOP00000022149Cullin 4B; Belongs to the cullin family. (831 aa)
rpa2Replication protein A2. (278 aa)
LOC114138536BTB domain-containing protein. (531 aa)
Cul4aCullin 4A; Belongs to the cullin family. (753 aa)
DtlDenticleless E3 ubiquitin protein ligase homolog (Drosophila). (735 aa)
ENSXCOP00000003814Methionine sulfoxide reductase B1b. (403 aa)
Rpa3Replication protein A3. (120 aa)
LOC114138068Ribosomal protein S27a. (156 aa)
ENSXCOP00000004968DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (523 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
Rfc4Replication factor C (activator 1) 4. (325 aa)
LOC114133261Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
ENSXCOP00000008359Ubiquitin carboxyl-terminal hydrolase. (779 aa)
ENSXCOP00000010388WD_REPEATS_REGION domain-containing protein. (138 aa)
ENSXCOP00000013093Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (554 aa)
Rfc3Replication factor C (activator 1) 3. (333 aa)
ENSXCOP00000013308Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (589 aa)
ENSXCOP00000014165SCY domain-containing protein. (122 aa)
Pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (145 aa)
Pold4Uncharacterized protein. (72 aa)
Wdr48WD repeat domain 48b. (519 aa)
ENSXCOP00000018217RFC1 domain-containing protein. (149 aa)
ENSXCOP00000018218BRCT domain-containing protein. (450 aa)
Ddb1Damage-specific DNA binding protein 1. (981 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (149 aa)
Pold2Polymerase (DNA directed), delta 2, regulatory subunit. (471 aa)
rfc2Replication factor C (activator 1) 2. (357 aa)
PoleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2225 aa)
LOC114149001Ubiquitin-like domain-containing protein. (77 aa)
Pold1DNA polymerase. (1089 aa)
ENSXCOP00000024658ATPase family AAA domain containing 5a. (1287 aa)
RCBTB1Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (531 aa)
ENSXCOP00000026621Polymerase (DNA-directed), delta 3, accessory subunit. (412 aa)
ENSXCOP00000026801RAD18 E3 ubiquitin protein ligase. (374 aa)
ENSXCOP00000027383KxDL motif containing 1. (193 aa)
Your Current Organism:
Xiphophorus couchianus
NCBI taxonomy Id: 32473
Other names: Limia couchiana, Monterrey platyfish, X. couchianus
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