107 items (Xiphophorus couchianus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC114136304	Nerve growth factor b (beta polypeptide); Belongs to the NGF-beta family. (194 aa)
	ENSXCOP00000021170	MCF.2 cell line derived transforming sequence a. (779 aa)
	Arhgef37	Rho guanine nucleotide exchange factor (GEF) 37. (773 aa)
	ENSXCOP00000020222	Uncharacterized protein. (678 aa)
	ENSXCOP00000019857	GSAP-16 domain-containing protein. (165 aa)
	Lingo2	Leucine rich repeat and Ig domain containing 2a. (617 aa)
	ENSXCOP00000019536	PR domain containing 4. (861 aa)
	ENSXCOP00000019479	Sequestosome 1. (283 aa)
	ENSXCOP00000018865	DH domain-containing protein. (277 aa)
	ENSXCOP00000018734	Intersectin 1 (SH3 domain protein). (800 aa)
	ENSXCOP00000018733	Uncharacterized protein. (433 aa)
	ENSXCOP00000018691	Rho guanine nucleotide exchange factor (GEF) 10-like a. (885 aa)
	Nfkbia	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (323 aa)
	traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (570 aa)
	Bcl2l11	Uncharacterized protein. (209 aa)
	ENSXCOP00000017544	T cell lymphoma invasion and metastasis 2a. (1442 aa)
	ENSXCOP00000016983	Rho guanine nucleotide exchange factor (GEF) 17. (426 aa)
	ENSXCOP00000016900	Rho guanine nucleotide exchange factor (GEF) 12a. (1148 aa)
	ENSXCOP00000015789	T cell lymphoma invasion and metastasis 1a. (1248 aa)
	ARHGEF26	Rho guanine nucleotide exchange factor 26. (822 aa)
	ENSXCOP00000015228	Uncharacterized protein. (200 aa)
	ENSXCOP00000014986	Rho guanine nucleotide exchange factor (GEF) 38. (674 aa)
	FGD3	FYVE, RhoGEF and PH domain containing 3. (671 aa)
	ENSXCOP00000014492	DH domain-containing protein. (368 aa)
	ENSXCOP00000014293	Son of sevenless homolog 1 (Drosophila). (435 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (615 aa)
	ENSXCOP00000014258	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (417 aa)
	ENSXCOP00000013790	DH domain-containing protein. (286 aa)
	ENSXCOP00000013536	Si:ch1073-396h14.1. (630 aa)
	Myd88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (306 aa)
	ENSXCOP00000013177	MCF.2 cell line derived transforming sequence-like 2. (707 aa)
	RTN1	Reticulon. (400 aa)
	ENSXCOP00000012312	Ras protein-specific guanine nucleotide-releasing factor 2b. (1180 aa)
	ENSXCOP00000011840	Uncharacterized protein. (66 aa)
	LOC114158792	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (301 aa)
	mag	Myelin associated glycoprotein. (630 aa)
	ENSXCOP00000010074	Rho guanine nucleotide exchange factor (GEF) 3, like. (489 aa)
	ENSXCOP00000010012	TGc domain-containing protein. (604 aa)
	FGD4	FYVE, RhoGEF and PH domain containing 4. (690 aa)
	ENSXCOP00000009735	Receptor-interacting serine-threonine kinase 2. (575 aa)
	ENSXCOP00000009015	MCF.2 cell line derived transforming sequence b. (787 aa)
	Arhgef11	DH domain-containing protein. (284 aa)
	ENSXCOP00000008847	PDZ domain-containing protein. (477 aa)
	ENSXCOP00000008547	Uncharacterized protein. (536 aa)
	ENSXCOP00000007945	Uncharacterized protein. (454 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	ENSXCOP00000007168	SH3 domain-containing protein. (118 aa)
	Tiam1	PH domain-containing protein. (613 aa)
	Omg	Oligodendrocyte myelin glycoprotein b. (373 aa)
	ENSXCOP00000006947	Vav 2 guanine nucleotide exchange factor. (770 aa)
	ENSXCOP00000006491	BCL2 associated agonist of cell death b. (149 aa)
	LOC114140283	Leucine rich repeat and Ig domain containing 4b. (604 aa)
	Aatf	Apoptosis antagonizing transcription factor. (539 aa)
	Arhgef16	Rho guanine nucleotide exchange factor (GEF) 16. (717 aa)
	Sos2	Son of sevenless homolog 2 (Drosophila). (1142 aa)
	LOC114138068	Ribosomal protein S27a. (156 aa)
	ENSXCOP00000003751	Neuroepithelial cell transforming 1. (501 aa)
	ENSXCOP00000003108	Rho/rac guanine nucleotide exchange factor (GEF) 18b. (850 aa)
	ENSXCOP00000002969	ADAM metallopeptidase domain 17a. (725 aa)
	ENSXCOP00000002575	Rho guanine nucleotide exchange factor (GEF) 39. (328 aa)
	Trio	DH domain-containing protein. (806 aa)
	ENSXCOP00000002539	Trio Rho guanine nucleotide exchange factor a. (1068 aa)
	ENSXCOP00000002395	annotation not available (228 aa)
	ENSXCOP00000002242	DH domain-containing protein. (216 aa)
	ENSXCOP00000002237	SH3 domain-containing protein. (131 aa)
	ENSXCOP00000002136	Inhibitor of nuclear factor kappa B kinase subunit beta. (708 aa)
	ENSXCOP00000000707	Nerve growth factor receptor b. (407 aa)
	ENSXCOP00000000624	Rho guanine nucleotide exchange factor (GEF) 19. (910 aa)
	LOC114143579	APH1B gamma secretase subunit. (258 aa)
	ENSXCOP00000000023	PDZ domain-containing protein. (228 aa)
	ENSXCOP00000027960	Leucine rich repeat and Ig domain containing 1a. (620 aa)
	VAV3	Vav guanine nucleotide exchange factor 3. (868 aa)
	ENSXCOP00000027913	Uncharacterized protein. (559 aa)
	ARHGEF2	Rho/rac guanine nucleotide exchange factor (GEF) 2. (831 aa)
	ENSXCOP00000027383	KxDL motif containing 1. (193 aa)
	ENSXCOP00000027303	DH domain-containing protein. (707 aa)
	ENSXCOP00000027171	Rho guanine nucleotide exchange factor (GEF) 7b. (520 aa)
	LOC114156394	Ig-like domain-containing protein. (609 aa)
	ENSXCOP00000026370	ADAM metallopeptidase domain 17b. (490 aa)
	Adam17	Pep_M12B_propep domain-containing protein. (221 aa)
	ENSXCOP00000026351	Rho guanine nucleotide exchange factor (GEF) 25b. (511 aa)
	NCSTN	Nicastrin. (647 aa)
	ENSXCOP00000025928	Uncharacterized protein. (413 aa)
	Casp2	Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (454 aa)
	Arhgef1	DH domain-containing protein. (265 aa)
	ENSXCOP00000025402	Uncharacterized protein. (276 aa)
	ENSXCOP00000025391	Calponin-homology (CH) domain-containing protein. (152 aa)
	ARHGEF7	Rho guanine nucleotide exchange factor 7. (405 aa)
	ENSXCOP00000025136	Rho guanine nucleotide exchange factor (GEF) 7a. (402 aa)
	ENSXCOP00000025124	Mcf.2 cell line derived transforming sequence-like b. (943 aa)
	ENSXCOP00000025077	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (565 aa)
	ENSXCOP00000025033	Uncharacterized protein. (1211 aa)
	Sestd1	SEC14 and spectrin domains 1. (722 aa)
	LOC114160019	Rho GDP dissociation inhibitor (GDI) alpha. (205 aa)
	ENSXCOP00000023520	Ras protein-specific guanine nucleotide-releasing factor 2a. (1209 aa)
	ENSXCOP00000023449	Nerve growth factor receptor a (TNFR superfamily, member 16). (287 aa)
	ARHGEF3	Rho guanine nucleotide exchange factor 3. (339 aa)
	ENSXCOP00000023320	Uncharacterized protein. (499 aa)
	LOC114149001	Ubiquitin-like domain-containing protein. (77 aa)
	ENSXCOP00000022507	Kalirin RhoGEF kinase a. (1592 aa)
	ENSXCOP00000022327	Kalirin RhoGEF kinase b. (454 aa)
	ENSXCOP00000022323	Uncharacterized protein. (302 aa)
	ENSXCOP00000022319	CRAL-TRIO domain-containing protein. (152 aa)
	ENSXCOP00000022052	FYVE, RhoGEF and PH domain containing 1. (767 aa)
	ENSXCOP00000022015	Interleukin-1 receptor-associated kinase 1. (639 aa)
	ENSXCOP00000021701	Uncharacterized protein. (3061 aa)
	Arhgef6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6. (745 aa)

Your Current Organism:

Xiphophorus couchianus

NCBI taxonomy Id: 32473
Other names: Limia couchiana, Monterrey platyfish, X. couchianus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGEF2	ENSXCOP00000018733	ENSXCOP00000027834	ENSXCOP00000018733	Rho/rac guanine nucleotide exchange factor (GEF) 2.	Uncharacterized protein.	0.459
ARHGEF2	ENSXCOP00000018734	ENSXCOP00000027834	ENSXCOP00000018734	Rho/rac guanine nucleotide exchange factor (GEF) 2.	Intersectin 1 (SH3 domain protein).	0.459
ARHGEF2	ENSXCOP00000027303	ENSXCOP00000027834	ENSXCOP00000027303	Rho/rac guanine nucleotide exchange factor (GEF) 2.	DH domain-containing protein.	0.460
ARHGEF2	LOC114138068	ENSXCOP00000027834	ENSXCOP00000004814	Rho/rac guanine nucleotide exchange factor (GEF) 2.	Ribosomal protein S27a.	0.407
ARHGEF7	ENSXCOP00000018733	ENSXCOP00000025139	ENSXCOP00000018733	Rho guanine nucleotide exchange factor 7.	Uncharacterized protein.	0.538
ARHGEF7	ENSXCOP00000018734	ENSXCOP00000025139	ENSXCOP00000018734	Rho guanine nucleotide exchange factor 7.	Intersectin 1 (SH3 domain protein).	0.538
ARHGEF7	ENSXCOP00000025136	ENSXCOP00000025139	ENSXCOP00000025136	Rho guanine nucleotide exchange factor 7.	Rho guanine nucleotide exchange factor (GEF) 7a.	0.891
ARHGEF7	ENSXCOP00000027303	ENSXCOP00000025139	ENSXCOP00000027303	Rho guanine nucleotide exchange factor 7.	DH domain-containing protein.	0.423
Aatf	LOC114138068	ENSXCOP00000005496	ENSXCOP00000004814	Apoptosis antagonizing transcription factor.	Ribosomal protein S27a.	0.554
Adam17	ENSXCOP00000002969	ENSXCOP00000026366	ENSXCOP00000002969	Pep_M12B_propep domain-containing protein.	ADAM metallopeptidase domain 17a.	0.901
Adam17	ENSXCOP00000023449	ENSXCOP00000026366	ENSXCOP00000023449	Pep_M12B_propep domain-containing protein.	Nerve growth factor receptor a (TNFR superfamily, member 16).	0.542
Adam17	ENSXCOP00000026370	ENSXCOP00000026366	ENSXCOP00000026370	Pep_M12B_propep domain-containing protein.	ADAM metallopeptidase domain 17b.	0.673
Arhgef1	Arhgef11	ENSXCOP00000025597	ENSXCOP00000008851	DH domain-containing protein.	DH domain-containing protein.	0.903
Arhgef1	Arhgef6	ENSXCOP00000025597	ENSXCOP00000021491	DH domain-containing protein.	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6.	0.934
Arhgef1	ENSXCOP00000016983	ENSXCOP00000025597	ENSXCOP00000016983	DH domain-containing protein.	Rho guanine nucleotide exchange factor (GEF) 17.	0.449
Arhgef1	ENSXCOP00000018733	ENSXCOP00000025597	ENSXCOP00000018733	DH domain-containing protein.	Uncharacterized protein.	0.463
Arhgef1	ENSXCOP00000018734	ENSXCOP00000025597	ENSXCOP00000018734	DH domain-containing protein.	Intersectin 1 (SH3 domain protein).	0.463
Arhgef1	ENSXCOP00000027171	ENSXCOP00000025597	ENSXCOP00000027171	DH domain-containing protein.	Rho guanine nucleotide exchange factor (GEF) 7b.	0.934
Arhgef1	ENSXCOP00000027303	ENSXCOP00000025597	ENSXCOP00000027303	DH domain-containing protein.	DH domain-containing protein.	0.460
Arhgef11	Arhgef1	ENSXCOP00000008851	ENSXCOP00000025597	DH domain-containing protein.	DH domain-containing protein.	0.903