42 items (Xiphophorus couchianus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSXCOP00000024891	UBA domain-containing protein. (130 aa)
	ENSXCOP00000000034	Tyrosine-protein phosphatase domain-containing protein. (231 aa)
	Hck	Tyrosine-protein kinase. (518 aa)
	Grb2	Growth factor receptor-bound protein 2b. (210 aa)
	ENSXCOP00000001764	Rap guanine nucleotide exchange factor (GEF) 1b. (1048 aa)
	jak3	Tyrosine-protein kinase. (1104 aa)
	LOC114138068	Ribosomal protein S27a. (156 aa)
	CRK	CRK proto-oncogene, adaptor protein. (315 aa)
	ENSXCOP00000006076	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (939 aa)
	LOC114149322	Tyrosine-protein kinase. (1124 aa)
	Pik3cb	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1079 aa)
	crkl	V-crk avian sarcoma virus CT10 oncogene homolog-like. (299 aa)
	ENSXCOP00000007305	Tyrosine-protein kinase. (546 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	Inpp5d	SH2 domain-containing protein. (47 aa)
	ENSXCOP00000008237	Uncharacterized protein. (408 aa)
	ENSXCOP00000008498	GRB2-associated binding protein 2. (661 aa)
	ENSXCOP00000009300	Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (662 aa)
	LOC114141391	Uncharacterized protein. (461 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
	Blk	Tyrosine-protein kinase. (404 aa)
	ENSXCOP00000010067	Uncharacterized protein. (509 aa)
	Cblc	Cbl proto-oncogene C, E3 ubiquitin protein ligase. (507 aa)
	ENSXCOP00000010846	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (944 aa)
	ENSXCOP00000010848	PI3K-ABD domain-containing protein; Belongs to the PI3/PI4-kinase family. (128 aa)
	ENSXCOP00000010958	Tyrosine-protein kinase. (1075 aa)
	Syk	Spleen tyrosine kinase. (271 aa)
	ENSXCOP00000012274	Uncharacterized protein. (100 aa)
	ENSXCOP00000012623	Tyrosine-protein kinase. (1119 aa)
	YES1	Tyrosine-protein kinase. (548 aa)
	ENSXCOP00000016600	Uncharacterized protein. (453 aa)
	ENSXCOP00000016904	Cbl proto-oncogene, E3 ubiquitin protein ligase. (903 aa)
	ENSXCOP00000018652	Tyrosine-protein kinase. (482 aa)
	ENSXCOP00000021141	Inositol polyphosphate phosphatase-like 1b. (1132 aa)
	ENSXCOP00000021901	Tyrosine-protein kinase. (543 aa)
	LOC114149001	Ubiquitin-like domain-containing protein. (77 aa)
	ENSXCOP00000023527	SH2 domain-containing protein. (67 aa)
	Pik3r1	Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (521 aa)
	ENSXCOP00000023963	Uncharacterized protein. (677 aa)
	CBL	Uncharacterized protein. (479 aa)
	Ptpn6	Protein tyrosine phosphatase non-receptor type 6. (549 aa)
	ENSXCOP00000026173	SHC (Src homology 2 domain containing) transforming protein 1. (459 aa)

Your Current Organism:

Xiphophorus couchianus

NCBI taxonomy Id: 32473
Other names: Limia couchiana, Monterrey platyfish, X. couchianus

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Blk	CBL	ENSXCOP00000009930	ENSXCOP00000024893	Tyrosine-protein kinase.	Uncharacterized protein.	0.477
Blk	CRK	ENSXCOP00000009930	ENSXCOP00000005850	Tyrosine-protein kinase.	CRK proto-oncogene, adaptor protein.	0.451
Blk	Cblc	ENSXCOP00000009930	ENSXCOP00000010328	Tyrosine-protein kinase.	Cbl proto-oncogene C, E3 ubiquitin protein ligase.	0.477
Blk	ENSXCOP00000000034	ENSXCOP00000009930	ENSXCOP00000000034	Tyrosine-protein kinase.	Tyrosine-protein phosphatase domain-containing protein.	0.423
Blk	ENSXCOP00000007305	ENSXCOP00000009930	ENSXCOP00000007305	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.424
Blk	ENSXCOP00000012274	ENSXCOP00000009930	ENSXCOP00000012274	Tyrosine-protein kinase.	Uncharacterized protein.	0.423
Blk	ENSXCOP00000016904	ENSXCOP00000009930	ENSXCOP00000016904	Tyrosine-protein kinase.	Cbl proto-oncogene, E3 ubiquitin protein ligase.	0.477
Blk	ENSXCOP00000018652	ENSXCOP00000009930	ENSXCOP00000018652	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.427
Blk	ENSXCOP00000021141	ENSXCOP00000009930	ENSXCOP00000021141	Tyrosine-protein kinase.	Inositol polyphosphate phosphatase-like 1b.	0.474
Blk	ENSXCOP00000023527	ENSXCOP00000009930	ENSXCOP00000023527	Tyrosine-protein kinase.	SH2 domain-containing protein.	0.423
Blk	ENSXCOP00000023963	ENSXCOP00000009930	ENSXCOP00000023963	Tyrosine-protein kinase.	Uncharacterized protein.	0.417
Blk	ENSXCOP00000024891	ENSXCOP00000009930	ENSXCOP00000024891	Tyrosine-protein kinase.	UBA domain-containing protein.	0.477
Blk	ENSXCOP00000026173	ENSXCOP00000009930	ENSXCOP00000026173	Tyrosine-protein kinase.	SHC (Src homology 2 domain containing) transforming protein 1.	0.496
Blk	Grb2	ENSXCOP00000009930	ENSXCOP00000000623	Tyrosine-protein kinase.	Growth factor receptor-bound protein 2b.	0.583
Blk	Inpp5d	ENSXCOP00000009930	ENSXCOP00000007821	Tyrosine-protein kinase.	SH2 domain-containing protein.	0.474
Blk	Ptpn6	ENSXCOP00000009930	ENSXCOP00000025781	Tyrosine-protein kinase.	Protein tyrosine phosphatase non-receptor type 6.	0.423
Blk	Syk	ENSXCOP00000009930	ENSXCOP00000011054	Tyrosine-protein kinase.	Spleen tyrosine kinase.	0.553
Blk	crkl	ENSXCOP00000009930	ENSXCOP00000006931	Tyrosine-protein kinase.	V-crk avian sarcoma virus CT10 oncogene homolog-like.	0.451
CBL	Blk	ENSXCOP00000024893	ENSXCOP00000009930	Uncharacterized protein.	Tyrosine-protein kinase.	0.477
CBL	CRK	ENSXCOP00000024893	ENSXCOP00000005850	Uncharacterized protein.	CRK proto-oncogene, adaptor protein.	0.786