24 items (Xiphophorus couchianus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RCBTB1	Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (531 aa)
	rpa2	Replication protein A2. (278 aa)
	Rev3l	DNA_pol_B domain-containing protein. (389 aa)
	ENSXCOP00000002001	REV3 like, DNA directed polymerase zeta catalytic subunit. (2197 aa)
	LOC114138536	BTB domain-containing protein. (531 aa)
	Mad2l2	Mitotic arrest deficient 2 like 2. (200 aa)
	ENSXCOP00000003814	Methionine sulfoxide reductase B1b. (403 aa)
	Rpa3	Replication protein A3. (120 aa)
	LOC114138068	Ribosomal protein S27a. (156 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	Rfc4	Replication factor C (activator 1) 4. (325 aa)
	LOC114133261	Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
	ENSXCOP00000013093	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (554 aa)
	Rfc3	Replication factor C (activator 1) 3. (333 aa)
	ENSXCOP00000013308	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (589 aa)
	ENSXCOP00000018217	RFC1 domain-containing protein. (149 aa)
	ENSXCOP00000018218	BRCT domain-containing protein. (450 aa)
	rfc2	Replication factor C (activator 1) 2. (357 aa)
	Polk	Polymerase (DNA directed) kappa. (366 aa)
	LOC114149001	Ubiquitin-like domain-containing protein. (77 aa)
	ENSXCOP00000024658	ATPase family AAA domain containing 5a. (1287 aa)
	ENSXCOP00000025145	REV1 DNA directed polymerase. (813 aa)
	ENSXCOP00000027383	KxDL motif containing 1. (193 aa)

Your Current Organism:

Xiphophorus couchianus

NCBI taxonomy Id: 32473
Other names: Limia couchiana, Monterrey platyfish, X. couchianus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSXCOP00000002001	ENSXCOP00000003814	ENSXCOP00000002001	ENSXCOP00000003814	REV3 like, DNA directed polymerase zeta catalytic subunit.	Methionine sulfoxide reductase B1b.	0.621
ENSXCOP00000002001	ENSXCOP00000013093	ENSXCOP00000002001	ENSXCOP00000013093	REV3 like, DNA directed polymerase zeta catalytic subunit.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.638
ENSXCOP00000002001	ENSXCOP00000013308	ENSXCOP00000002001	ENSXCOP00000013308	REV3 like, DNA directed polymerase zeta catalytic subunit.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.638
ENSXCOP00000002001	ENSXCOP00000018217	ENSXCOP00000002001	ENSXCOP00000018217	REV3 like, DNA directed polymerase zeta catalytic subunit.	RFC1 domain-containing protein.	0.672
ENSXCOP00000002001	ENSXCOP00000018218	ENSXCOP00000002001	ENSXCOP00000018218	REV3 like, DNA directed polymerase zeta catalytic subunit.	BRCT domain-containing protein.	0.672
ENSXCOP00000002001	ENSXCOP00000024658	ENSXCOP00000002001	ENSXCOP00000024658	REV3 like, DNA directed polymerase zeta catalytic subunit.	ATPase family AAA domain containing 5a.	0.665
ENSXCOP00000002001	ENSXCOP00000025145	ENSXCOP00000002001	ENSXCOP00000025145	REV3 like, DNA directed polymerase zeta catalytic subunit.	REV1 DNA directed polymerase.	0.969
ENSXCOP00000002001	LOC114149001	ENSXCOP00000002001	ENSXCOP00000023106	REV3 like, DNA directed polymerase zeta catalytic subunit.	Ubiquitin-like domain-containing protein.	0.532
ENSXCOP00000002001	Mad2l2	ENSXCOP00000002001	ENSXCOP00000003563	REV3 like, DNA directed polymerase zeta catalytic subunit.	Mitotic arrest deficient 2 like 2.	0.970
ENSXCOP00000002001	Polk	ENSXCOP00000002001	ENSXCOP00000022457	REV3 like, DNA directed polymerase zeta catalytic subunit.	Polymerase (DNA directed) kappa.	0.906
ENSXCOP00000002001	Rev3l	ENSXCOP00000002001	ENSXCOP00000001600	REV3 like, DNA directed polymerase zeta catalytic subunit.	DNA_pol_B domain-containing protein.	0.944
ENSXCOP00000002001	Rfc3	ENSXCOP00000002001	ENSXCOP00000013300	REV3 like, DNA directed polymerase zeta catalytic subunit.	Replication factor C (activator 1) 3.	0.757
ENSXCOP00000002001	Rfc4	ENSXCOP00000002001	ENSXCOP00000007624	REV3 like, DNA directed polymerase zeta catalytic subunit.	Replication factor C (activator 1) 4.	0.757
ENSXCOP00000002001	Rpa3	ENSXCOP00000002001	ENSXCOP00000003918	REV3 like, DNA directed polymerase zeta catalytic subunit.	Replication protein A3.	0.647
ENSXCOP00000002001	pcna	ENSXCOP00000002001	ENSXCOP00000006594	REV3 like, DNA directed polymerase zeta catalytic subunit.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.953
ENSXCOP00000002001	rfc2	ENSXCOP00000002001	ENSXCOP00000022248	REV3 like, DNA directed polymerase zeta catalytic subunit.	Replication factor C (activator 1) 2.	0.757
ENSXCOP00000002001	rpa2	ENSXCOP00000002001	ENSXCOP00000000909	REV3 like, DNA directed polymerase zeta catalytic subunit.	Replication protein A2.	0.613
ENSXCOP00000002001	uba52	ENSXCOP00000002001	ENSXCOP00000007438	REV3 like, DNA directed polymerase zeta catalytic subunit.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.532
ENSXCOP00000003814	ENSXCOP00000002001	ENSXCOP00000003814	ENSXCOP00000002001	Methionine sulfoxide reductase B1b.	REV3 like, DNA directed polymerase zeta catalytic subunit.	0.621
ENSXCOP00000003814	ENSXCOP00000018217	ENSXCOP00000003814	ENSXCOP00000018217	Methionine sulfoxide reductase B1b.	RFC1 domain-containing protein.	0.672