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| | Gen1 | Chromo_2 domain-containing protein. (637 aa) |
| | ENSXCOP00000022273 | ANK_REP_REGION domain-containing protein. (400 aa) |
| | rfc2 | Replication factor C (activator 1) 2. (357 aa) |
| | rmi2 | RecQ mediated genome instability 2. (146 aa) |
| | Rad51c | RAD51 paralog C. (361 aa) |
| | Helq | Abraxas 1, BRCA1 A complex subunit. (377 aa) |
| | ENSXCOP00000021451 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (675 aa) |
| | Pold2 | Polymerase (DNA directed), delta 2, regulatory subunit. (471 aa) |
| | ENSXCOP00000020142 | Uncharacterized protein. (588 aa) |
| | ube2v2 | Ubiquitin-conjugating enzyme E2 variant 2. (180 aa) |
| | LOC114146450 | Histone H2B; Belongs to the histone H2B family. (116 aa) |
| | ccna2 | Cyclin A2; Belongs to the cyclin family. (432 aa) |
| | ENSXCOP00000019422 | EF-hand domain-containing protein. (1130 aa) |
| | ENSXCOP00000019170 | Sirtuin 7. (421 aa) |
| | ENSXCOP00000019083 | Exonuclease 3'-5' domain containing 2. (583 aa) |
| | ENSXCOP00000018891 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2484 aa) |
| | ENSXCOP00000018850 | Uncharacterized protein. (106 aa) |
| | LOC114134311 | Small ubiquitin-related modifier. (94 aa) |
| | Exo1 | Exonuclease 1. (692 aa) |
| | LOC114161189 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (155 aa) |
| | rhno1 | Si:ch73-352p4.5. (297 aa) |
| | Rad51ap1 | RAD51 associated protein 1. (293 aa) |
| | ENSXCOP00000018218 | BRCT domain-containing protein. (450 aa) |
| | ENSXCOP00000018217 | RFC1 domain-containing protein. (149 aa) |
| | ENSXCOP00000017691 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (101 aa) |
| | ENSXCOP00000017667 | annotation not available (93 aa) |
| | ENSXCOP00000017612 | Histone H2B; Belongs to the histone H2B family. (111 aa) |
| | LOC114145030 | Small ubiquitin-related modifier. (96 aa) |
| | ENSXCOP00000017338 | Histone H2B; Belongs to the histone H2B family. (134 aa) |
| | ENSXCOP00000017337 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa) |
| | Mre11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (664 aa) |
| | ENSXCOP00000016765 | Ring finger protein 168. (353 aa) |
| | Topbp1 | DNA topoisomerase II binding protein 1. (1484 aa) |
| | Dna2 | Uncharacterized protein. (1054 aa) |
| | ENSXCOP00000015627 | Histone H2B; Belongs to the histone H2B family. (151 aa) |
| | HIST1H4J | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (96 aa) |
| | ENSXCOP00000015465 | Histone H2B; Belongs to the histone H2B family. (124 aa) |
| | Pold4 | Uncharacterized protein. (72 aa) |
| | ENSXCOP00000014852 | BRISC and BRCA1 A complex member 2. (358 aa) |
| | Pole4 | Polymerase (DNA-directed), epsilon 4, accessory subunit. (145 aa) |
| | ppp4c | Serine/threonine-protein phosphatase. (311 aa) |
| | ENSXCOP00000013329 | MUS81 structure-specific endonuclease subunit. (538 aa) |
| | Ccna1 | Cyclin A1; Belongs to the cyclin family. (397 aa) |
| | ENSXCOP00000013308 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (589 aa) |
| | Rfc3 | Replication factor C (activator 1) 3. (333 aa) |
| | ENSXCOP00000013093 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (554 aa) |
| | Ppp4r2 | Protein phosphatase 4, regulatory subunit 2b. (406 aa) |
| | ENSXCOP00000011797 | BRISC and BRCA1 A complex member 1. (313 aa) |
| | ENSXCOP00000011653 | Uncharacterized protein. (168 aa) |
| | sirt6 | Sirtuin 6. (351 aa) |
| | rad51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (338 aa) |
| | ENSXCOP00000009556 | Histone H2B; Belongs to the histone H2B family. (112 aa) |
| | ENSXCOP00000008860 | BRCA1/BRCA2-containing complex, subunit 3. (258 aa) |
| | ENSXCOP00000008859 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (101 aa) |
| | Mus81 | Uncharacterized protein. (66 aa) |
| | ENSXCOP00000008228 | Uncharacterized protein. (1176 aa) |
| | LOC114133261 | Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa) |
| | Rfc4 | Replication factor C (activator 1) 4. (325 aa) |
| | ENSXCOP00000007607 | RAD50 homolog, double strand break repair protein. (1233 aa) |
| | uba52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa) |
| | ENSXCOP00000007270 | Reverse transcriptase domain-containing protein. (269 aa) |
| | ENSXCOP00000007078 | Uncharacterized protein. (1182 aa) |
| | ENSXCOP00000006663 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (94 aa) |
| | HIST1H2BA | Histone H2B; Belongs to the histone H2B family. (115 aa) |
| | ENSXCOP00000022277 | BRCT domain-containing protein. (149 aa) |
| | Polk | Polymerase (DNA directed) kappa. (366 aa) |
| | Pole | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2225 aa) |
| | LOC114149001 | Ubiquitin-like domain-containing protein. (77 aa) |
| | ENSXCOP00000023176 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (411 aa) |
| | LOC114159801 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa) |
| | Pold1 | DNA polymerase. (1089 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (264 aa) |
| | Rad51d | RAD51 paralog D. (337 aa) |
| | RCBTB1 | Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (531 aa) |
| | ENSXCOP00000026229 | Uncharacterized protein. (236 aa) |
| | ENSXCOP00000026234 | FHA domain-containing protein. (99 aa) |
| | ENSXCOP00000026597 | RecQ helicase-like 4. (795 aa) |
| | ENSXCOP00000026621 | Polymerase (DNA-directed), delta 3, accessory subunit. (412 aa) |
| | Blm | BLM RecQ like helicase. (1379 aa) |
| | Rad52 | Uncharacterized protein. (163 aa) |
| | ENSXCOP00000027383 | KxDL motif containing 1. (193 aa) |
| | Ube2n | Ubiquitin-conjugating enzyme E2Na; Belongs to the ubiquitin-conjugating enzyme family. (173 aa) |
| | LOC114138068 | Ribosomal protein S27a. (156 aa) |
| | SLX1 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (266 aa) |
| | ankrd11 | Ankyrin repeat domain 11. (2824 aa) |
| | ENSXCOP00000004072 | Essential meiotic structure-specific endonuclease 1. (362 aa) |
| | Rpa3 | Replication protein A3. (120 aa) |
| | ENSXCOP00000003814 | Methionine sulfoxide reductase B1b. (403 aa) |
| | Abl1 | Protein kinase domain-containing protein. (223 aa) |
| | Xrcc2 | RECA_2 domain-containing protein. (304 aa) |
| | ube2i | Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa) |
| | HUS1 | Checkpoint protein; Belongs to the HUS1 family. (277 aa) |
| | Rad1 | RAD1 homolog (S. pombe). (202 aa) |
| | ENSXCOP00000003115 | Uncharacterized protein. (90 aa) |
| | RNF8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (467 aa) |
| | Rad9a | Cell cycle checkpoint control protein; Belongs to the rad9 family. (396 aa) |
| | Tipin | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (319 aa) |
| | Tdrd3 | Tudor domain containing 3. (798 aa) |
| | LOC114138536 | BTB domain-containing protein. (531 aa) |
| | Xrcc3 | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (362 aa) |
| | rpa2 | Replication protein A2. (278 aa) |
| | ENSXCOP00000000492 | Histone H2B; Belongs to the histone H2B family. (147 aa) |
| | Polh | Polymerase (DNA directed), eta. (696 aa) |
| | ENSXCOP00000000335 | ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2879 aa) |
| | sumo2 | Small ubiquitin-related modifier. (95 aa) |
| | ENSXCOP00000004968 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (523 aa) |
| | ENSXCOP00000005616 | Uncharacterized protein. (217 aa) |
| | ENSXCOP00000005688 | PWWP domain-containing protein. (226 aa) |
| | Nsd2 | Nuclear receptor binding SET domain protein 2. (522 aa) |
| | Rbbp8 | SAE2 domain-containing protein. (75 aa) |
| | pcna | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa) |
| | ENSXCOP00000006635 | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (627 aa) |
