STRINGSTRING
ankrd11 ankrd11 Taf10 Taf10 ENSXCOP00000004324 ENSXCOP00000004324 Nuak2 Nuak2 LOC114138068 LOC114138068 ENSXCOP00000004885 ENSXCOP00000004885 Tp53rk Tp53rk ENSXCOP00000005714 ENSXCOP00000005714 Noc2l Noc2l prkab1 prkab1 Rbbp8 Rbbp8 ENSXCOP00000006635 ENSXCOP00000006635 Tbpl1 Tbpl1 Pin1 Pin1 ENSXCOP00000007167 ENSXCOP00000007167 uba52 uba52 ENSXCOP00000007607 ENSXCOP00000007607 Rfc4 Rfc4 ENSXCOP00000008228 ENSXCOP00000008228 ENSXCOP00000008718 ENSXCOP00000008718 ENSXCOP00000008869 ENSXCOP00000008869 Taf6 Taf6 ENSXCOP00000010095 ENSXCOP00000010095 mapkapk5 mapkapk5 ENSXCOP00000010396 ENSXCOP00000010396 LOC114142755 LOC114142755 Stk11 Stk11 PRKAB2 PRKAB2 Taf12 Taf12 prkaa2 prkaa2 ENSXCOP00000011653 ENSXCOP00000011653 taf13 taf13 ENSXCOP00000000335 ENSXCOP00000000335 ENSXCOP00000000841 ENSXCOP00000000841 rpa2 rpa2 ENSXCOP00000000977 ENSXCOP00000000977 ENSXCOP00000001319 ENSXCOP00000001319 LOC114155887 LOC114155887 Tp53 Tp53 Tdrd3 Tdrd3 LOC114142078 LOC114142078 ENSXCOP00000012709 ENSXCOP00000012709 prkaa1 prkaa1 ENSXCOP00000013093 ENSXCOP00000013093 Rfc3 Rfc3 ENSXCOP00000013308 ENSXCOP00000013308 Ccna1 Ccna1 ENSXCOP00000013719 ENSXCOP00000013719 ENSXCOP00000013991 ENSXCOP00000013991 Taf5l Taf5l TAF4 TAF4 ENSXCOP00000015339 ENSXCOP00000015339 ENSXCOP00000015358 ENSXCOP00000015358 ENSXCOP00000015401 ENSXCOP00000015401 ENSXCOP00000015521 ENSXCOP00000015521 Dna2 Dna2 Tbp Tbp Topbp1 Topbp1 Taf5 Taf5 ENSXCOP00000016575 ENSXCOP00000016575 ENSXCOP00000016807 ENSXCOP00000016807 Mre11 Mre11 Dyrk2 Dyrk2 ENSXCOP00000017161 ENSXCOP00000017161 rhno1 rhno1 ENSXCOP00000018459 ENSXCOP00000018459 Exo1 Exo1 ENSXCOP00000018850 ENSXCOP00000018850 ENSXCOP00000018891 ENSXCOP00000018891 ENSXCOP00000019083 ENSXCOP00000019083 Cdk5r2 Cdk5r2 ENSXCOP00000019638 ENSXCOP00000019638 ENSXCOP00000019641 ENSXCOP00000019641 ccna2 ccna2 ENSXCOP00000020027 ENSXCOP00000020027 ENSXCOP00000020549 ENSXCOP00000020549 ENSXCOP00000021451 ENSXCOP00000021451 ENSXCOP00000021707 ENSXCOP00000021707 ENSXCOP00000021847 ENSXCOP00000021847 ENSXCOP00000022045 ENSXCOP00000022045 rmi2 rmi2 ENSXCOP00000022118 ENSXCOP00000022118 rfc2 rfc2 ENSXCOP00000022273 ENSXCOP00000022273 ENSXCOP00000022277 ENSXCOP00000022277 ENSXCOP00000022771 ENSXCOP00000022771 ENSXCOP00000022870 ENSXCOP00000022870 LOC114149001 LOC114149001 ENSXCOP00000023176 ENSXCOP00000023176 ENSXCOP00000023265 ENSXCOP00000023265 ENSXCOP00000023756 ENSXCOP00000023756 ENSXCOP00000024552 ENSXCOP00000024552 ENSXCOP00000024620 ENSXCOP00000024620 ENSXCOP00000024680 ENSXCOP00000024680 ENSXCOP00000024706 ENSXCOP00000024706 CDK2 CDK2 ENSXCOP00000026157 ENSXCOP00000026157 ENSXCOP00000026229 ENSXCOP00000026229 ENSXCOP00000026234 ENSXCOP00000026234 Prkag1 Prkag1 ENSXCOP00000026597 ENSXCOP00000026597 Blm Blm ENSXCOP00000027131 ENSXCOP00000027131 ENSXCOP00000027383 ENSXCOP00000027383 CSNK2A2 CSNK2A2 ENSXCOP00000027706 ENSXCOP00000027706 Taf3 Taf3 ENSXCOP00000002465 ENSXCOP00000002465 ENSXCOP00000002516 ENSXCOP00000002516 Rad9a Rad9a ENSXCOP00000002822 ENSXCOP00000002822 ENSXCOP00000003115 ENSXCOP00000003115 Rad1 Rad1 ENSXCOP00000003227 ENSXCOP00000003227 HUS1 HUS1 ENSXCOP00000003814 ENSXCOP00000003814 Rpa3 Rpa3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ankrd11Ankyrin repeat domain 11. (2824 aa)
Taf10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (136 aa)
ENSXCOP00000004324Uncharacterized protein. (156 aa)
Nuak2NUAK family, SNF1-like kinase, 2. (564 aa)
LOC114138068Ribosomal protein S27a. (156 aa)
ENSXCOP00000004885Protein kinase domain-containing protein. (209 aa)
Tp53rkTP53 regulating kinase. (214 aa)
ENSXCOP00000005714Tumor protein p53 inducible nuclear protein 1. (222 aa)
Noc2lNOC2-like nucleolar associated transcriptional repressor. (729 aa)
prkab1Protein kinase, AMP-activated, beta 1 non-catalytic subunit, a. (269 aa)
Rbbp8SAE2 domain-containing protein. (75 aa)
ENSXCOP00000006635RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (627 aa)
Tbpl1TBP-like 1. (182 aa)
Pin1WW domain-containing protein. (132 aa)
ENSXCOP00000007167Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4; Belongs to the protein kinase superfamily. (485 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
ENSXCOP00000007607RAD50 homolog, double strand break repair protein. (1233 aa)
Rfc4Replication factor C (activator 1) 4. (325 aa)
ENSXCOP00000008228Uncharacterized protein. (1176 aa)
ENSXCOP00000008718Transcription initiation factor TFIID subunit. (1822 aa)
ENSXCOP00000008869SPT16 homolog, facilitates chromatin remodeling subunit. (974 aa)
Taf6TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (652 aa)
ENSXCOP00000010095Homeodomain interacting protein kinase 2. (1155 aa)
mapkapk5MAPK activated protein kinase 5. (471 aa)
ENSXCOP00000010396Protein kinase, AMP-activated, beta 1 non-catalytic subunit, b. (107 aa)
LOC114142755Uncharacterized protein. (182 aa)
Stk11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (436 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (269 aa)
Taf12TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (178 aa)
prkaa2Non-specific serine/threonine protein kinase. (557 aa)
ENSXCOP00000011653Uncharacterized protein. (168 aa)
taf13TATA-box binding protein associated factor 13. (125 aa)
ENSXCOP00000000335ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2879 aa)
ENSXCOP00000000841Uncharacterized protein. (313 aa)
rpa2Replication protein A2. (278 aa)
ENSXCOP00000000977Aurora kinase B; Belongs to the protein kinase superfamily. (301 aa)
ENSXCOP00000001319Zgc:86598; Belongs to the protein kinase superfamily. (336 aa)
LOC114155887Cyclin-dependent kinase 5 activator. (323 aa)
Tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (332 aa)
Tdrd3Tudor domain containing 3. (798 aa)
LOC114142078Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
ENSXCOP00000012709Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily. (299 aa)
prkaa1Non-specific serine/threonine protein kinase. (564 aa)
ENSXCOP00000013093Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (554 aa)
Rfc3Replication factor C (activator 1) 3. (333 aa)
ENSXCOP00000013308Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (589 aa)
Ccna1Cyclin A1; Belongs to the cyclin family. (397 aa)
ENSXCOP00000013719Protein kinase domain-containing protein. (303 aa)
ENSXCOP00000013991Cyclin-dependent kinase 5 activator. (308 aa)
Taf5lTAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor. (606 aa)
TAF4TATA-box binding protein associated factor 4. (607 aa)
ENSXCOP00000015339Mitogen-activated protein kinase. (353 aa)
ENSXCOP00000015358MDM2 proto-oncogene; Belongs to the MDM2/MDM4 family. (454 aa)
ENSXCOP00000015401TATA box binding protein like 2. (156 aa)
ENSXCOP00000015521Homeodomain interacting protein kinase 3b. (1172 aa)
Dna2Uncharacterized protein. (1054 aa)
TbpTATA box binding protein. (304 aa)
Topbp1DNA topoisomerase II binding protein 1. (1484 aa)
Taf5TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (782 aa)
ENSXCOP00000016575Checkpoint kinase 2. (499 aa)
ENSXCOP00000016807TAFH domain-containing protein. (912 aa)
Mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (664 aa)
Dyrk2Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2. (607 aa)
ENSXCOP00000017161TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (204 aa)
rhno1Si:ch73-352p4.5. (297 aa)
ENSXCOP00000018459Aurora kinase A; Belongs to the protein kinase superfamily. (393 aa)
Exo1Exonuclease 1. (692 aa)
ENSXCOP00000018850Uncharacterized protein. (106 aa)
ENSXCOP00000018891ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2484 aa)
ENSXCOP00000019083Exonuclease 3'-5' domain containing 2. (583 aa)
Cdk5r2Cyclin-dependent kinase 5, regulatory subunit 2b (p39). (296 aa)
ENSXCOP00000019638Uncharacterized protein. (161 aa)
ENSXCOP00000019641Protein kinase, AMP-activated, gamma 2 non-catalytic subunit b. (321 aa)
ccna2Cyclin A2; Belongs to the cyclin family. (432 aa)
ENSXCOP00000020027Cyclin-dependent kinase 5. (267 aa)
ENSXCOP00000020549Homeodomain interacting protein kinase 1a. (1079 aa)
ENSXCOP00000021451DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (675 aa)
ENSXCOP00000021707TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (335 aa)
ENSXCOP00000021847TAFH domain-containing protein. (843 aa)
ENSXCOP00000022045Uncharacterized protein. (483 aa)
rmi2RecQ mediated genome instability 2. (146 aa)
ENSXCOP00000022118Uncharacterized protein. (249 aa)
rfc2Replication factor C (activator 1) 2. (357 aa)
ENSXCOP00000022273ANK_REP_REGION domain-containing protein. (400 aa)
ENSXCOP00000022277BRCT domain-containing protein. (149 aa)
ENSXCOP00000022771TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (1135 aa)
ENSXCOP00000022870Protein kinase, AMP-activated, gamma 3b non-catalytic subunit. (336 aa)
LOC114149001Ubiquitin-like domain-containing protein. (77 aa)
ENSXCOP00000023176Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (411 aa)
ENSXCOP00000023265TAFH domain-containing protein. (565 aa)
ENSXCOP00000023756Si:ch211-160o17.4. (1127 aa)
ENSXCOP00000024552TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (232 aa)
ENSXCOP00000024620Mitogen-activated protein kinase 14b. (103 aa)
ENSXCOP00000024680MDM4 regulator of p53; Belongs to the MDM2/MDM4 family. (456 aa)
ENSXCOP00000024706Dual specificity tyrosine phosphorylation regulated kinase 3. (590 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (264 aa)
ENSXCOP00000026157Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (149 aa)
ENSXCOP00000026229Uncharacterized protein. (236 aa)
ENSXCOP00000026234FHA domain-containing protein. (99 aa)
Prkag1Protein kinase, AMP-activated, gamma 1 non-catalytic subunit. (299 aa)
ENSXCOP00000026597RecQ helicase-like 4. (795 aa)
BlmBLM RecQ like helicase. (1379 aa)
ENSXCOP00000027131Protein kinase, AMP-activated, gamma 3a non-catalytic subunit. (339 aa)
ENSXCOP00000027383KxDL motif containing 1. (193 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (299 aa)
ENSXCOP00000027706Protein kinase domain-containing protein. (1170 aa)
Taf3TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto. (934 aa)
ENSXCOP00000002465Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (342 aa)
ENSXCOP00000002516TPX2 microtubule nucleation factor. (630 aa)
Rad9aCell cycle checkpoint control protein; Belongs to the rad9 family. (396 aa)
ENSXCOP00000002822FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (594 aa)
ENSXCOP00000003115Uncharacterized protein. (90 aa)
Rad1RAD1 homolog (S. pombe). (202 aa)
ENSXCOP00000003227Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (332 aa)
HUS1Checkpoint protein; Belongs to the HUS1 family. (277 aa)
ENSXCOP00000003814Methionine sulfoxide reductase B1b. (403 aa)
Rpa3Replication protein A3. (120 aa)
Your Current Organism:
Xiphophorus couchianus
NCBI taxonomy Id: 32473
Other names: Limia couchiana, Monterrey platyfish, X. couchianus
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