STRINGSTRING
Mtor Mtor ENSXCOP00000000335 ENSXCOP00000000335 LOC114161603 LOC114161603 Tp53 Tp53 Pdpk1 Pdpk1 Mlst8 Mlst8 LOC114138068 LOC114138068 Ppp2ca Ppp2ca ENSXCOP00000005738 ENSXCOP00000005738 ENSXCOP00000005938 ENSXCOP00000005938 SGK1 SGK1 uba52 uba52 ppp2r1b ppp2r1b ENSXCOP00000010985 ENSXCOP00000010985 ENSXCOP00000011364 ENSXCOP00000011364 LOC114138792 LOC114138792 Ccna1 Ccna1 Akt1 Akt1 ENSXCOP00000015358 ENSXCOP00000015358 ENSXCOP00000016575 ENSXCOP00000016575 ENSXCOP00000016598 ENSXCOP00000016598 ENSXCOP00000017452 ENSXCOP00000017452 ENSXCOP00000017651 ENSXCOP00000017651 ENSXCOP00000017654 ENSXCOP00000017654 ENSXCOP00000017812 ENSXCOP00000017812 Cdk1 Cdk1 ccna2 ccna2 ENSXCOP00000020744 ENSXCOP00000020744 ENSXCOP00000021325 ENSXCOP00000021325 ENSXCOP00000021870 ENSXCOP00000021870 ENSXCOP00000022210 ENSXCOP00000022210 ENSXCOP00000022211 ENSXCOP00000022211 LOC114149001 LOC114149001 ENSXCOP00000023454 ENSXCOP00000023454 usp7 usp7 ENSXCOP00000024680 ENSXCOP00000024680 CDK2 CDK2 ENSXCOP00000025238 ENSXCOP00000025238 ENSXCOP00000025345 ENSXCOP00000025345 ENSXCOP00000027383 ENSXCOP00000027383
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MtorMechanistic target of rapamycin kinase. (922 aa)
ENSXCOP00000000335ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2879 aa)
LOC114161603Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
Tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (332 aa)
Pdpk13-phosphoinositide dependent protein kinase 1b. (538 aa)
Mlst8MTOR associated protein, LST8 homolog (S. cerevisiae). (349 aa)
LOC114138068Ribosomal protein S27a. (156 aa)
Ppp2caSerine/threonine-protein phosphatase. (221 aa)
ENSXCOP00000005738Ring finger protein 34b. (363 aa)
ENSXCOP00000005938PR domain containing 1a, with ZNF domain. (664 aa)
SGK1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (420 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
ppp2r1bProtein phosphatase 2, regulatory subunit A, beta b. (589 aa)
ENSXCOP00000010985V-akt murine thymoma viral oncogene homolog 3b; Belongs to the protein kinase superfamily. (498 aa)
ENSXCOP00000011364Cyclin G1; Belongs to the cyclin family. (278 aa)
LOC114138792Serine/threonine-protein phosphatase. (309 aa)
Ccna1Cyclin A1; Belongs to the cyclin family. (397 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (442 aa)
ENSXCOP00000015358MDM2 proto-oncogene; Belongs to the MDM2/MDM4 family. (454 aa)
ENSXCOP00000016575Checkpoint kinase 2. (499 aa)
ENSXCOP00000016598Serine/threonine-protein phosphatase. (300 aa)
ENSXCOP00000017452Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase. (330 aa)
ENSXCOP00000017651V-akt murine thymoma viral oncogene homolog 3a. (162 aa)
ENSXCOP00000017654Protein kinase domain-containing protein. (75 aa)
ENSXCOP00000017812Uncharacterized protein. (113 aa)
Cdk1Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (224 aa)
ccna2Cyclin A2; Belongs to the cyclin family. (432 aa)
ENSXCOP00000020744Ring finger protein 34a. (190 aa)
ENSXCOP00000021325Thioredoxin domain containing 11. (853 aa)
ENSXCOP00000021870MAPK associated protein 1. (489 aa)
ENSXCOP00000022210Uncharacterized protein. (75 aa)
ENSXCOP00000022211Uncharacterized protein. (100 aa)
LOC114149001Ubiquitin-like domain-containing protein. (77 aa)
ENSXCOP00000023454Uncharacterized protein. (101 aa)
usp7Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1104 aa)
ENSXCOP00000024680MDM4 regulator of p53; Belongs to the MDM2/MDM4 family. (456 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (264 aa)
ENSXCOP00000025238Ubiquitin carboxyl-terminal hydrolase. (398 aa)
ENSXCOP00000025345PR domain containing 1b, with ZNF domain. (761 aa)
ENSXCOP00000027383KxDL motif containing 1. (193 aa)
Your Current Organism:
Xiphophorus couchianus
NCBI taxonomy Id: 32473
Other names: Limia couchiana, Monterrey platyfish, X. couchianus
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